In Brazil, a group of researchers has reported the largest outbreak to date of COVID-associated candidemia caused by the same drug-resistant strain of Candida parapsilosis, a fungus that invades the bloodstream and can lead to death.
Mechanisms involved in the rapid, severe progression of fibrosis in the lung tissues of COVID-19 patients, a potentially fatal complication of the virus that damages and scars the lungs, have been uncovered by researchers led by UTHealth Houston.
With a new $3 million-plus grant from the National Institutes of Health (NIH), Case Western Reserve University researchers are examining the next level of treatment for Candida auris (C.auris), a multidrug-resistant yeast that causes serious infection and, in some cases, death.
With COVID-19 and flu cases rising, and RSV (respiratory syncytial virus) affecting many young children, experts are bracing for a “tripledemic” of respiratory viruses this holiday season.
COVID-19 has had a lasting global health impact that continues to challenge the health care system.
West Nile, Zika, dengue and malaria are all diseases spread by bites from infected mosquitoes.
The Pfizer-BioNTech COVID-19 vaccine limits transmission, hospitalization, and death from COVID-19 even among patients infected by variants of the virus, but the effectiveness of antibodies it generates diminishes as patients get older, according to a study by UT Southwestern researchers.
Groundbreaking research by Argonne National Laboratory finds new method to quickly identify COVID-19 virus variants. Their work wins the Gordon Bell Special Prize.
A study of more than 1,000 health care workers was unable to establish whether medical masks are significantly less effective at preventing COVID-19 infection than N95 respirators in hospital settings. The findings varied across countries, which were studied during different times in the pandemic, and uncertainty in the estimates of effect limit definitiveness of findings. The study is published in Annals of Internal Medicine.
An observational study of COVID-19 standard of care (SOC) measures found improvements in recovery and mortality over time in adults hospitalized with COVID-19 and investigated changes in SOC that may explain these improvements. The study is published in Annals of Internal Medicine.
A brief research report found that despite 20.8 percent fewer COVID-19 deaths occurring in the second year of the COVID-19 pandemic, 7.4 percent more years of life were lost due to a shift in COVID-19 mortality to relatively younger people. The report is published in Annals of Internal Medicine.
An award-winning scheme that saw community pharmacists support patients to understand the benefits of being jabbed against Covid-19 and overcome initial hesitancy proved hugely successful, new research by an expert from Kingston University has shown.
Once considered a potentially static field of medicine, the discipline of studying infectious diseases has proven to be dynamic as emerging and reemerging infectious diseases present continuous challenges, Anthony S. Fauci, M.D., writes in a perspective in The New England Journal of Medicine.
A new WWARN meta-analysis commissioned by the World Health Organization (WHO) which informed a change to its treatment guidelines* has been published in The Lancet.
In an intensive look at the effects of the virus causing COVID-19 on patients’ microbiome – the collection of microorganisms that live in and on the human body – Rutgers scientists found that acute infection disrupts a healthy balance between good and bad microbes in the gut, especially with antibiotic treatment.
Researchers working with Sbarro Health Research Organization (SHRO) have published a paper examining the possible links between neurological involvement and respiratory damage due to COVID-19.
Researchers of the University of Bristol-led study, published in Science Advances today [23 November], say their findings could lead to the development of a pan-coronavirus treatment to defeat all coronaviruses.
Researchers at the University of São Paulo (USP) in Brazil have found that severe COVID-19 is associated with an imbalance in an important immune system signaling pathway.
Research by psychologists from the School of Psychology at Swansea University found that people’s fear of COVID-19 has led to worsened mental health.
The COVID-19 pandemic has led to an explosion of clinical research resulting in the development of a variety of vaccines and treatments, although the efficacy of some remains controversial.
Researchers show that great bustards in Spain prefer to eat two plant species with compounds active in vitro against protozoa, nematodes, and fungi: corn poppies and purple viper’s bugloss. Males, who spend much time and energy on sexual displays during the mating season, have a stronger preference for these plants than females, and more so during the mating season than at other times of the year. The authors thus consider great bustards as prime candidates for non-human animals that self-medicate, but stress that more research is needed to definitively prove this.
Three currently circulating omicron subvariants of SARS-CoV-2 – including two that currently make up almost 50% of reported COVID-19 infections in the U.S. – are better at evading vaccine- and infection-generated neutralizing antibodies than earlier versions of omicron, new research suggests.
Individuals previously infected with SARS-CoV-2, the virus that causes COVID-19, still benefit from vaccination, gaining 60% to 94% protection against reinfection, depending on the variant. A new study led by Katrine Finderup Nielsen at Statens Serum Institut, Denmark, reports these findings November 22nd in the open access journal PLOS Medicine.
A new study released today in Nature Communications from the Department of Biology, University of Oxford has found the first direct evidence of antibiotic resistant bacteria migrating from a patient’s gut microbiome to the lungs.
Alcohol-based disinfectants are effective against enveloped viruses.
Reporting a positive or negative test result just became easier through a new website from the National Institutes of Health. MakeMyTestCount.org, developed through NIH’s Rapid Acceleration of Diagnostics (RADx®) Tech program, allows users to anonymously report the results of any brand of at-home COVID-19 test.
Though antiretroviral therapy has made HIV a manageable disease, people living with HIV often suffer from chronic inflammation. This can put them at an increased risk of developing comorbidities such as cardiovascular disease and neurocognitive dysfunction, impacting the longevity and quality of their lives.
When an epidemic strikes, more than just infections spread. As cases mount, information about the disease, how to spot it, and how to prevent it propagates rapidly among people in affected areas as well.
UC Davis Health infectious diseases expert George Thompson warns of the rising threat and apparent spread of disease-causing fungi outside their traditional hot spots. Fungal lung infections are commonly misdiagnosed, leading to delays in treatment and increase in antimicrobial resistance in the community.
Tick bites transmit Lyme disease. But even knowing where these ticks live doesn’t necessarily mean you can predict the disease in humans.
An international team of scientists investigating transmission of a deadly drug resistant bacteria that rivals MRSA, has found that whilst the bugs are found in livestock, pets and the wider environment, they are rarely transmitted to humans through this route.
In a paper recently published in Malaria Journal, global health researchers, Daniel Parker, PhD, assistant professor, and Guiyun Yan, PhD, professor, both from the UCI Program in Public Health, analyzed the movement ecology of humans in two places of heightened importance for Ethiopia’s malaria control and elimination strategies: Gambella and Benishangul-Gumuz (on the international border with Sudan and South Sudan).
Given the anticipated increase in COVID-19 and influenza cases this fall and winter, America’s healthcare professional organizations are coming together to remind the public of the importance of vaccinations and early treatment.
Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.
Scientists discuss what may come next as SARS-CoV-2 evolves and why COVID-19 won’t be our last pandemic
Irvine, Calif., Nov. 17, 2022 – Researchers at the University of California, Irvine have discovered that the safe operation of a negative pressure room – a space in a hospital or biological research laboratory designed to protect outside areas from exposure to deadly pathogens – can be disrupted by an attacker armed with little more than a smartphone.
Two studies published by The BMJ today provide up to date evidence on the effectiveness of both currently licensed and possible covid-19 treatments under everyday (‘real world’) conditions, helping to shed more light on whether these drugs can prevent people from becoming seriously ill.
Epidemiologists at the University of Illinois Chicago (UIC) developed and implemented a novel, student-driven, contact-tracing program that reduced COVID-19 exposures and infections on the campus during the 2020-2021 school year.
Researchers at Karolinska Institutet in Sweden have shown that patients with acute COVID-19 infection have increased levels of the cytokine IL-26 in their blood.
COVID-19 reactivated viruses that had become latent in cells following previous infections, particularly in people with chronic fatigue syndrome, also known as ME/CFS.
With what some are calling a “tripledemic” of COVID-19, the influenza virus and respiratory syncytial virus, or RSV, soaring in many parts of the country, the holiday season will come with some tough decisions again this year.
COVID-19 reactivated viruses that had become latent in cells following previous infections, particularly in people with chronic fatigue syndrome, also known as ME/CFS.
Cambridge scientists have used synthetic biology to create artificial enzymes programmed to target the genetic code of SARS-CoV-2 and destroy the virus, an approach that could be used to develop a new generation of antiviral drugs.
Preserving and restoring natural habitats could prevent pathogens that originate in wildlife from spilling over into domesticated animals and humans, according to two new companion studies.
The 2022 "Highly Cited Researchers" list from Clarivate includes several La Jolla Institute for Immunology (LJI) scientists well versed in lay friendly communication. These experts are ready to share exciting new research with media and podcast outlets. Contact [email protected] to set up an interview and make arrangements for high quality audio capture.
Some people believe that public health measures against COVID-19, including masking and social distancing, have resulted in children getting more sick now because of a weakened immune system. Experts disagree about whether “immunity debt” is a real phenomenon or convenient pseudoscience.
mRNA vaccines for COVID-19 generate adverse reactions such as fever and fatigue which are considered normal and are transient in nature.
Although the coronavirus known as SARS-CoV-2 does not infect nerve cells, it can cause damage to the nervous system.
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