Daniel Herranz Benito, PharmD, PhD, resident researcher at Rutgers Cancer Institute of New Jersey, has received a five-year, $600,000 award from the Leukemia and Lymphoma Society (LLS) to support ongoing research efforts in T-cell acute lymphoblastic leukemia (T-ALL).
A small group of brain cells linked in a circuit is responsible for setting off whole-brain seizures in a rare form of epilepsy affected by blood sugar levels, a study led by UT Southwestern researchers suggests. The finding, published in Science Translational Medicine, could lead to new treatments for other metabolic disorders in the brain, the authors said.
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. Current advances include a promising targeted therapy combination for patients with relapsed/refractory acute myeloid leukemia (AML), a link between the gut microbiome and therapy-related neutropenic fever, a novel therapeutic target for immunotherapy-related colitis, a telementoring model for training providers on cervical cancer prevention in limited-resource areas, a new understanding of the prognostic value of RUNX1 mutations in AML, and insights into the effects of opioid use on the pain sensitivity pathway.
The National Institutes of Health has awarded Albert Einstein College of Medicine a five-year, $6.6 million grant to lead a New York-based consortium of medical schools to train young scientists in kidney, urology, and hematology research.
Researchers from the University of Missouri School of Medicine have discovered how obstructive sleep apnea (OSA) changes the profiles of immune cells in the blood, leading to a unique cellular signature that can accurately detect obstructive sleep apnea in children.
The recovery of Jesus Torres, a patient at Loyola Medicine with acute myeloid leukemia, highlights the importance of access to innovative, experimental treatments for blood cancers for all communities. As a world-class research institute, Loyola Medicine provides unique, life-saving therapies through its participation in clinical trials, such as a phase 3 clinical trial that uses umbilical cord blood transplantation to treat patients with acute myeloid leukemia.
Scientists from Oxford University and the University of Birmingham have made the first bone marrow ‘organoids’ that capture the key features of human bone marrow.
Did you ever think of jellyfish or a salamander as fluorescent? That is actually the case. Both animals have proteins in their bodies that enables them to light up.
Hosted by Chulalongkorn University the APRU APEC University Leaders' Forum 2022 is the first post-pandemic in-person APEC meeting held to foster high-level dialogue between CEOs, policy leaders, university presidents, and top researchers. This event begins Nov 15 at 9 PM EST.
The advent of cell phones, the internet, and various messaging platforms has allowed for faster and broader communication worldwide.
Scientists have used a proteomics approach to identify a three-protein signature in the blood that can improve detection of isolated impaired glucose tolerance, a form of prediabetes.
In a study of pregnant women in the United States, Cedars-Sinai investigators found that a specific imbalance of two placental proteins could predict which women were at risk of developing a severe form of preeclampsia, a life-threatening blood pressure disorder.
Here are some of the latest articles that have been added to the Arthritis channel on Newswise.
De acuerdo a un nuevo análisis dirigido por investigadores de Cedars-Sinai y llevado a cabo en tres grandes sistemas de salud, el control y manejo de la hipertensión empeoraron durante los primeros meses de la pandemia de COVID-19.
Pioneering research into the chronic inflammation often seen in certain blood cancers has identified a promising treatment approach for myelofibrosis, a potentially deadly bone marrow cancer.
New research presented this week at ACR Convergence 2022, the American College of Rheumatology’s annual meeting, found that adult RA patients starting opioids had twice the risk of venous thromboembolism (VTE) compared to patients starting nonsteroidal anti-inflammatory drugs (NSAIDs).
New research presented this week at ACR Convergence 2022, the American College of Rheumatology’s annual meeting, demonstrated an association between age of diagnosis and clinical characteristics and treatments in Anti-neutrophil cytoplasmic antibody-associated vasculitis patients.
Researchers have discovered the vital role of a hormone, that develops in men during puberty, in providing an early prediction of whether they could develop certain diseases in later life.
estoring blood flow to the legs, whether through bypass surgery or a less invasive artery-opening procedure with a stent, reduced pain and improved quality of life for people with peripheral artery disease (PAD), according to preliminary, late-breaking research presented today at the American Heart Association’s Scientific Sessions 2022.
A former fellow at the UNM Comprehensive Cancer Center, Dr. Shashank Cingam comes back to New Mexico to Treat blood cancers.
Multicentric Castleman disease (MCD) comprises a heterogenous group of rare disorders that exhibit generalized symptoms such as swelling of lymph nodes, anemia, fever, and fatigue.
Mount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the blood cancer multiple myeloma who try an immunotherapy known as CAR-T only to find their cancer coming back afterwards.
The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts.
A targeted therapy for children with high-risk Hodgkin lymphoma significantly reduced relapse rates, a large multicenter clinical trial conducted by the Children’s Oncology Group shows. The study results have been reported in the New England Journal of Medicine.
The Flow Cytometry Core at Sanford Burnham Prebys is getting a new piece of state-of-the-art research equipment, thanks to a grant from the National Institutes of Health.
Adults with hypertension saw a small, but consequential, rise in their blood pressure levels during the first eight months of the COVID-19 pandemic, while the number of times they had their blood pressure measured dropped significantly, according to a study supported by the National Institutes of Health.
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Memorial Sloan Kettering Cancer Center (MSK) announced today that the U.S. Food and Drug Administration (FDA) has approved the oral MEK inhibitor drug cobimetinib (Cotellic®) for the treatment of adult patients with the family of blood diseases known as histiocytic neoplasms (HN). These diseases include Erdheim-Chester disease, Rosai-Dorfman disease, and Langerhans cell histiocytosis. Cobimetinib is an oral inhibitor of MEK1 and MEK2, currently approved to treat melanoma.
Hypertension control and management worsened during the early months of the COVID-19 pandemic, according to a new analysis conducted at three large health systems, led by Cedars-Sinai investigators.
罗切斯特 ， 明尼苏达州 - 六十 前 ， ， 血液 骨髓 移植 只 种 尝试 救治血癌 试验性 疗法 ， 经过 年 发展 ， ， 如今 已然 种 重要 抗癌 手段。 当前 ， 医疗 医疗 医疗
Nas seis décadas em que o transplante de sangue e medula tem sido usado para tratar pacientes com câncer no sangue, esse tratamento experimental tornou-se uma ferramenta vital de combate ao câncer. A Mayo Clinic, em Rochester, Minnesota, está celebrando a marca de 10 mil transplantes sanguíneos e de medula usados para o tratamento de cânceres sanguíneos e de doenças relacionadas.
مدينة روتشستر، ولاية مينيسوتا. - على مدار الستة عقود الماضية منذ بداية استخدام عمليات زراعة الدم والنخاع لعلاج المرضى المصابين بسرطان الدم، أصبح هذا العلاج التجريبي أداة حيوية لمكافحة السرطان. تحتفل مايو كلينك في مدينة روتشستر بولاية مينيسوتا بإجراء 10,000 عملية زراعة دم ونخاع لعلاج سرطانات الدم والاضطرابات ذات الصلة.
En las seis décadas posteriores a que se comience a utilizar el trasplante de médula para tratar a pacientes con distintos tipos de cáncer de la sangre, este tratamiento, que en un principio fue experimental, se ha vuelto una herramienta vital para la lucha contra el cáncer. Mayo Clinic de Rochester (Minnesota) celebra el trasplante de sangre y médula ósea número 10 000 utilizado en el tratamiento de distintos tipos de cáncer de la sangre y trastornos relacionados.
The destruction of red blood cells, or mechanical hemolysis, is an inevitable complication of interventional devices, so scientists want to gain a better understanding of the phenomenon. In Physics of Fluids, researchers develop a red blood cell destruction model based on simulations of dissipative particle dynamics within a high shear flow. The team discovered that acceleration during shearing is a major factor in red blood cell destruction, beyond exposure time and shear stress. They recommend adding a flow buffer structure to the structural design of ventricular assist devices to reduce part of the hemolysis caused by shear acceleration.
A large-scale comparison of direct oral anticoagulants (blood thinners), commonly prescribed for irregular heartbeats, has identified the drug with the lowest risk of bleeding, in a new study led by UCL researchers.
A Roundup of the Latest Medical Discoveries and Faculty News at Cedars-Sinai
RUDN doctors have found genetic factors that increase the risk of recurrent vascular stenosis after stent placement. The data obtained will help to adjust the treatment and choose an individual approach for patients with coronary heart disease.
Physicists at McMaster University have identified a natural delivery system which can safely carry potent antibiotics throughout the body to selectively attack and kill bacteria by using red blood cells as a vehicle.
Researchers at Linköping University have identified in mice the cells in the blood vessels of the brain that are necessary for a fever reaction.
A global study of over 28,000 people has provided the strongest evidence to date that lowering blood pressure in later life can cut the risk of dementia.
Researchers at the Chan Zuckerberg Biohub (CZ Biohub), the Chan Zuckerberg Initiative (CZI), and UC San Francisco (UCSF) have developed a new diagnostic method that applies machine learning to advanced genomics data from both microbe and host – to identify and predict sepsis cases.
Approximately 500 healthy volunteers with no history of cancer are being sought to contribute blood cells that may be used in the development of cancer clinical trials.
The new study showed apixaban is superior to rivaroxaban against stroke or systemic embolism in patients with atrial fibrillation and valvular heart disease
Currently, the U.S. leads western nations in infant mortality and cardiac birth defects are a leading cause. New research harnesses the power of AI to detect dangerous cardiac abnormalities prenatally. Resulting medical protocols implemented at birth in those at-risk could go a long way toward saving lives.
Patients who have surgery to repair bone fractures typically receive a type of injectable blood thinner, low-molecular-weight heparin, to prevent life-threatening blood clots, but a new clinical trial found that over-the-counter aspirin is just as effective.
For the approximately 8.5 million people in the U.S. living with peripheral artery disease (PAD – pronounced P-A-D), which is narrowed or clogged arteries in the legs, treatment decisions and criteria for success should be led by their symptoms and self-reported quality of life, according to a new American Heart Association scientific statement published today in the Association’s flagship, peer-reviewed journal Circulation.
In 2015, published findings from the landmark Systolic Blood Pressure Intervention Trial (SPRINT) showed that intensive blood pressure management reduced cardiovascular disease and lowered the risk of death. In 2019, results of the SPRINT MIND trial showed that lowering blood pressure also reduced the risk of mild cognitive impairment in older adults. Now, researchers from Wake Forest University School of Medicine have shown that while intensive blood pressure control was beneficial to SPRINT participants’ health during the trial, the benefits for cardiovascular mortality went away after approximately two years when protocols for blood pressure management were no longer being followed.
St. Jude Children’s Research Hospital scientists found the cellular response to low oxygen also increases fetal hemoglobin expression in adults, which could lead to novel treatments for some common genetic anemias.
Predicting the rupture of aneurysms is crucial for medical prevention and treatment. As aspect ratio and size ratio increase and an aneurysm expands, the stress applied against the aneurysm walls and the time blood spends within it increase. This leads the probability of rupture to rise. In Physics of Fluids, researchers develop a patient-specific mathematical model to examine what aneurysm parameters influence rupture risk prior to surgery. Computed tomography scans are fed into the model, which reconstructs the geometry and blood flow of the aneurysm. It then uses equations to describe the fluid flow, generating information about the blood vessel walls and blood flow patterns.
In the six decades since blood and marrow transplantation was used to treat patients with blood cancers, this once experimental treatment has become a vital cancer-fighting tool. Mayo Clinic in Rochester, Minnesota, is celebrating the 10,000th blood and marrow transplant used in the treatment of blood cancers and related disorders.
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