Feature Channels: Vaccines

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Researchers at Rutgers Cancer Institute of New Jersey, Rutgers New Jersey Medical School (NJMS) and the Center for Theoretical Biological Physics (CTBP) at Rice University in Houston, Texas, have demonstrated that a technology with favorable biological attributes known as phage display could be a viable platform for the development of new vaccines to protect against COVID-19.

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A metabolic control pathway that regulates T follicular helper cells offers targets for drugs to stimulate the adaptive immune response.

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A new international study has found that the key properties of the spikes of SARS-CoV-2 virus which causes COVID-19 are consistent with those of several laboratory-developed protein spikes, designed to mimic the infectious virus.

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People who receive mRNA COVID-19 vaccines are up to 91 percent less likely to develop the disease than those who are unvaccinated, according to a new nationwide study of eight sites, including Salt Lake City. For those few vaccinated people who do still get an infection, or “breakthrough” cases, the study suggests that vaccines reduce the severity of COVID-19 symptoms and shorten its duration.

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Health experts have a new message for seniors, who they once cautioned to stay home and protect themselves against COVID-19: "As long as you are vaccinated, you can go out!" said Sonja Rosen, MD, chief of Geriatric Medicine at Cedars-Sinai.

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A new study out of UChicago found that while 43 states (out of 51, including all 50 states and Washington, D.C.) created a committee to develop a vaccine distribution plan, only 20 plans mentioned using a health equity committee to assist with plan development.

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Researchers have found that viral vaccines grown in eggs, such as the H1N1 flu vaccine, produce an antibody response against a sugar molecule found in eggs, which could have implications for the effectiveness of these vaccines.

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Researchers at La Jolla Institute for Immunology (LJI) have found that T cells from people who have recovered from COVID-19 or received the Moderna or Pfizer-BioNTech vaccines are still able to recognize several concerning SARS-CoV-2 variants.

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Researchers at UC San Diego Health have launched a pair of clinical trials to study the immune response of COVID-19 vaccinated transplant recipients of bone marrow and solid organs, such as the heart, lung, liver and kidney.

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UC San Diego Health is now offering a verifiable digital vaccine record to its patients who have or will receive a COVID-19 vaccine. These secure online records, otherwise known as a SMART health card, can be accessed directly from the MyUCSDChart patient portal.

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Patients with mild Covid-19 infections experience a significantly increased longer lasting reduced sense of taste and smell.

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Mayo Clinic researchers are taking a close look at rare cases of inflammation of the heart muscle, or myocarditis, in young men who developed symptoms shortly after receiving the second dose of the Moderna or Pfizer messenger RNA (mRNA) COVID-19 vaccines. Several recent studies suggest that health care professionals should watch for hypersensitivity myocarditis as a rare adverse reaction to being vaccinated for COVID-19. However, researchers stress that this awareness should not diminish overall confidence in vaccination during the current pandemic.

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A new grant will help Iowa State University researchers figure out how the microbiome, or all the microorganisms that live inside and on human systems, affects immunity and the effectiveness of vaccines. Not everyone responds to vaccines in identical ways, and the researchers will search for ways humans can adjust their microbiomes to optimize vaccine response.

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A new study from researchers at Washington University School of Medicine in St. Louis, published June 28 in the journal Nature, has found evidence that the immune response to Pfizer's mRNA vaccine against COVID-19 is both strong and potentially long-lasting.

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Patients with a type of blood cancer called multiple myeloma had a widely variable response to COVID-19 vaccines—in some cases, no detectable response—pointing to the need for antibody testing and precautions for these patients after vaccination, according to a study published in Cancer Cell in June.

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A new Covid-19 vaccine dashboard for the state of Georgia shows vaccination rates among white residents are higher than those of Black residents in all large metro counties, as well as in around 70% of all Georgia counties.

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Vanderbilt University Medical Center (VUMC) is enrolling volunteers ages 12-69 to take part in an NIH funded study to assess reactions to the Pfizer and Moderna COVID-19 vaccines in highly allergic individuals.

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UNC-Chapel Hill scientists investigated blood samples from children enrolled in a dengue vaccine trial to identify the specific kinds of antibody responses that correlate with protection against dengue virus disease.

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The virus that causes COVID-19 normally gets inside cells by attaching to a protein called ACE2. Researchers at Washington University School of Medicine in St. Louis have found that a single mutation confers the ability to enter cells through another route, which may threaten the effectiveness of COVID-19 vaccines and therapeutics designed to block the standard route of entry.