Filters close
Released: 24-Mar-2022 7:00 AM EDT
Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
Journal of Clinical Medicine

… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%), and periprocedural AF was not associated with higher risk of stroke. Risk of stroke after TAVR can be affected by various factors, including antithrombotic regimens …

Released: 22-Mar-2022 9:00 AM EDT
Immunological barriers to haematopoietic stem cell gene therapy
Nature Reviews Immunology

… Recent clinical successes for gene therapies involving autologous HSC transplantation (HSCT) demonstrate the potential of genetic engineering in this stem cell type for curing disease. With recent advances in CRISPR gene-editing …

Released: 22-Mar-2022 9:00 AM EDT
TAVR or SAVR? What can we learn from a pooled meta-analysis of reconstructed time to event data?
European Journal of Cardio-Thoracic Surgery

… of death of any cause or stroke, all-cause mortality, stroke and rehospitalization with a focus on … cause or stroke, the analysis of the HR trend over time shows the superiority of TAVR over … Again, the HR trend over time shows a survival …

Released: 21-Mar-2022 6:00 AM EDT
Cerebral Protection in TAVR—Can We Do Without? A Real-World All-Comer Intention-to-Treat Study—Impact on Stroke Rate, Length of Hospital Stay, and Twelve-Month Mortality
Journal of Personalized Medicine

… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

Released: 21-Mar-2022 6:00 AM EDT
Successful transfemoral-transcatheter aortic valve replacement in high-risk patients with a grade 4 atheroma in the ascending aorta: cerebral protection with a filter device
General Thoracic and Cardiovascular Surgery

… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

Released: 21-Mar-2022 6:00 AM EDT
The Heart Brain Team and Patient-Centered Management of Ischemic Stroke
Journal of the American College of Cardiology

… What is the role of routine cerebral embolic protection (CEP) with TAVR? Do all TAVR strokes occur because of intraprocedural catheter manipulations (Figure 7)? Are there neurological sequalae to the use of the CEP themselves? Can CEP be …

Released: 21-Mar-2022 6:00 AM EDT
Delivery of Stem Cell Secretome for Therapeutic Applications
ACS Applied Bio Materials

Delivery of Stem Cell Secretome for Therapeutic Applications F Li, J Zhang, K Yi, H Wang, H Wei, HF Chan, Y Tao… - ACS Applied Bio Materials, 2022 … delivery of stem cell secretome deserve more attention. In this review, we first discuss approaches for the production and characterization of stem cell secretome and their optimization strategies. Moreover, the up-to-date studies to improve the … [HTML] Cancer Stem Cell Markers for Urinary Carcinoma P Xia, DH Liu, ZJ Xu, F Ren - Stem Cells International, 2022 … Cancer stem cell (CSC) refers to cancer cells with stem cell properties, that is, they have the ability of “self-renewal” and “differentiation.” … In this review, cancer stem cell surface markers and functional markers in urinary system were summarized …

Released: 21-Mar-2022 6:00 AM EDT
Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
Journal of Clinical Medicine

… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%), and periprocedural AF was not associated with higher risk of stroke. Risk of stroke after TAVR can be affected by various factors, including antithrombotic regimens …

Released: 17-Mar-2022 12:05 PM EDT
Conspiracists Push Baseless Story of US-Backed Bioweapons in Ukraine
Newswise

Certain media outlets and social media posts are making the claim that the United States has established several biolabs in Ukraine, inferring that they contain dangerous bioweapons. We find this claim to be false. The U.S. does not fund bioweapons research in Ukraine. It has only supported preventative public health measures to contain infectious diseases, and prevention of bioweapon proliferation.

Released: 17-Mar-2022 7:00 AM EDT
CRT-700.12 TAVR Vascular Access Closure Using the Tri-Suture Technique
Journal of the American College of Cardiology: Cardiovascular Interventions

… remain high when compared to other TAVR related complications. We assessed outcomes in consecutive patients treated with TAVR using a novel Tri-… Non disabling stroke was observed in 1 patient. Median discharge was 1 day post TAVI …

Released: 17-Mar-2022 7:00 AM EDT
Cerebral Protection in TAVR—Can We Do Without? A Real-World All-Comer Intention-to-Treat Study—Impact on Stroke Rate, Length of Hospital Stay, and Twelve-Month Mortality
Journal of Personalized Medicine

… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

Released: 17-Mar-2022 7:00 AM EDT
Use of Direct Oral Anticoagulant and Outcomes in Patients With Atrial Fibrillation after Transcatheter Aortic Valve Replacement: Insights From the STS/ACC TVT Registry
Journal of the American Heart Association

… and use of OAC in patients with TAVR and AF, we excluded all patients with a prior mechanical valve, prior stroke within 1 year, in‐… In an analysis from a large clinical data registry of US patients with AF undergoing TAVR, we found that the 1‐year …

Released: 17-Mar-2022 7:00 AM EDT
Cerebral Embolic Protection and Stroke-Related Mortality Following Transcatheter Aortic Valve Replacement
Journal of the American College of Cardiology: Cardiovascular Interventions

… Therefore, we sought to assess the association between CEP and stroke-related mortality following TAVR using a large-scale US … mortality risk of stroke following TAVR. This result needs cautious interpretation because the sample size of stroke …

Released: 17-Mar-2022 7:00 AM EDT
Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
Journal of Clinical Medicine

… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%), and periprocedural AF was not associated with higher risk of stroke. Risk of stroke after TAVR can be affected by various factors, including antithrombotic regimens …

Released: 16-Mar-2022 7:05 AM EDT
Successful transfemoral-transcatheter aortic valve replacement in high-risk patients with a grade 4 atheroma in the ascending aorta: cerebral protection with a filter device
General Thoracic and Cardiovascular Surgery

… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

Released: 16-Mar-2022 7:05 AM EDT
Characterization of Cerebral Embolic Capture Using the SENTINEL Device During Transcatheter Aortic Valve Implantation in Low to IntermediateRisk Patients: The SENTINEL-LIR Study
Circulation: Cardiovascular Interventions

… Post-TAVR stroke causes acute and long-term morbidity and mortality. The stroke rate 30 days after TAVR was reported as 3.4% in low-risk … TAVR may reduce the incidence of ischemic stroke and in-hospital mortality.However, the effectiveness of …

Released: 16-Mar-2022 7:05 AM EDT
Cerebral Protection in TAVR—Can We Do Without? A Real-World All-Comer Intention-to-Treat Study—Impact on Stroke Rate, Length of Hospital Stay, and Twelve …
Journal of Personalized Medicine

… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

Released: 16-Mar-2022 7:05 AM EDT
Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
Journal of Clinical Medicine

… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%), and periprocedural AF was not associated with higher risk of stroke. Risk of stroke after TAVR can be affected by various factors, including antithrombotic regimens …

Released: 15-Mar-2022 9:00 AM EDT
ATP citrate lyase controls hematopoietic stem cell fate and supports bone marrow regeneration
The EMBO Journal

… protein C receptor (EPCRhigh) were enriched within the stem cell fraction at the expense of more proliferative EPCRLow HSCs. These … stem cell function. We herein attempted to elucidate the mechanisms by which HSCs convert the effects of …

Released: 15-Mar-2022 9:00 AM EDT
Safety of Transcatheter Aortic Valve Replacement in Patients with Aortic Aneurysm: A Propensity-Matched Analysis
Cardiology and Therapy

… Reports show that > 95% of endovascular TAVR in the US is via transfemoral access, so our population are mostly patients undergoing … in non-TAVR populations [28]. Our study shows that the procedure-related stroke rate was not …

Released: 15-Mar-2022 9:00 AM EDT
NK cell content does not seem to influence engraftment in ex vivo T cell depleted haploidentical stem cell transplantation
Stem Cell Reports

NK cell content does not seem to influence engraftment in ex vivo T cell depleted haploidentical stem cell tra … usefulness of NK cellderived IFNg inhibition to favor engraftment in allogeneic hematopoietic stem cell transplantation (HSCT) …

Released: 15-Mar-2022 9:00 AM EDT
Characterization of Cerebral Embolic Capture Using the SENTINEL Device During Transcatheter Aortic Valve Implantation in Low to IntermediateRisk Patients: The SENTINEL-LIR Study
Circulation: Cardiovascular Interventions

… Post-TAVR stroke causes acute and long-term morbidity and mortality. The stroke rate 30 days after TAVR was reported as 3.4% in low-risk … TAVR may reduce the incidence of ischemic stroke and in-hospital mortality.However, the effectiveness of …

Released: 15-Mar-2022 9:00 AM EDT
Mesenchymal stem cell treatment for COVID-19
eBioMedicine

… In addition, MSCs derived from different donors and tissues lead to individual heterogeneity, which complicates the progress of consistent and standardized stem cell production. Therefore, it is necessary to screen qualified MSCs to avoid uncertain effects. …

Released: 11-Mar-2022 8:05 AM EST
When it comes to masks, the claim that they do nothing is entirely false
Newswise

Political commentator and radio host Clay Travis expressed his disdain for the federal mask mandates for travel on commercial airlines. We rate the claim that "masks do nothing" as false. It has been proven that masks have helped prevent the spread of SARS-COV-2, the virus that causes COVID-19.

     
Released: 10-Mar-2022 6:00 AM EST
Successful transfemoral-transcatheter aortic valve replacement in high-risk patients with a grade 4 atheroma in the ascending aorta: cerebral protection with a filter device
General Thoracic and Cardiovascular Surgery

… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

Released: 9-Mar-2022 10:50 AM EST
Successful transfemoral-transcatheter aortic valve replacement in high-risk patients with a grade 4 atheroma in the ascending aorta: cerebral protection with a filter device
General Thoracic and Cardiovascular Surgery

… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

Released: 9-Mar-2022 10:50 AM EST
Adult stem cell niches for tissue homeostasis
Journal of Cellular Physiology

… stem cell niches, whose repairing ability is not able to overcome severe damage (heart or nervous tissue). The purpose of this review is to … the main characteristics of stem cell niches in these different tissues, highlighting the various components …

Released: 8-Mar-2022 6:00 AM EST
2-Year Outcomes After Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients
Journal of the American College of Cardiology

… primary endpoint of death or disabling stroke were 4.3% in the TAVR group and 6.3% in the … between years 1 and 2 as it relates to early TAVR benefits seen in death or disabling stroke. … used Bayesian statistical inference to predict that TAVR …

Released: 8-Mar-2022 6:00 AM EST
Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
Journal of Clinical Medicine

… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%), and periprocedural AF was not associated with higher risk of stroke. Risk of stroke after TAVR can be affected by various factors, including antithrombotic regimens …

Released: 8-Mar-2022 6:00 AM EST
Successful transfemoral-transcatheter aortic valve replacement in high-risk patients with a grade 4 atheroma in the ascending aorta: cerebral protection with a filter device
General Thoracic and Cardiovascular Surgery

… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

Released: 8-Mar-2022 6:00 AM EST
Cerebral Protection in TAVR—Can We Do Without? A Real-World All-Comer Intention-to-Treat Study—Impact on Stroke Rate, Length of Hospital Stay, and Twelve-Month Mortality
Journal of Personalized Medicine

… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

Released: 4-Mar-2022 9:40 AM EST
Schumer's claim that only one percent of the oil imported to the U.S. is from Russia is not correct
Newswise

During a press conference, a reporter asked Senate Majority Leader Sen. Chuck Schumer (D-NY, “What do you make of Senator Manchin’s proposal to have more domestic oil production?” Schumer answered, "the U.S. is a major oil producer; we only get one percent of any imports from Russia.” We find this claim to be mostly false. Although it fluctuates month to month, about 8% of the oil imported to the U.S. is from Russia.

     
Released: 4-Mar-2022 7:00 AM EST
Successful transfemoral-transcatheter aortic valve replacement in high-risk patients with a grade 4 atheroma in the ascending aorta: cerebral protection with a filter device
General Thoracic and Cardiovascular Surgery

… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

Released: 4-Mar-2022 7:00 AM EST
Cerebral Protection in TAVR—Can We Do Without? A Real-World All-Comer Intention-to-Treat Study—Impact on Stroke Rate, Length of Hospital Stay, and Twelve-Month Mortality
Journal of Personalized Medicine

… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

Released: 3-Mar-2022 6:00 AM EST
Use of Direct Oral Anticoagulant and Outcomes in Patients With Atrial Fibrillation after Transcatheter Aortic Valve Replacement: Insights From the STS/ACC TVT Registry
Journal of the American Heart Association

… and use of OAC in patients with TAVR and AF, we excluded all patients with a prior mechanical valve, prior stroke within 1 year, in‐… In an analysis from a large clinical data registry of US patients with AF undergoing TAVR, we found that the 1‐year …

Released: 3-Mar-2022 6:00 AM EST
Non‐vitamin K oral anticoagulants versus vitamin K antagonists in post transcatheter aortic valve replacement patients with clinical indication for oral anticoagulation: A meta‐analysis
Clinical Investigations

… Our meta‐analysis suggests that in post‐TAVR patients requiring OAC therapy, all‐cause mortality, stroke or systemic embolism, and major and/or life‐threatening bleeding are similar between the NOAC and VKA groups. The NOACs may be considered as …

Released: 3-Mar-2022 6:00 AM EST
Successful transfemoral-transcatheter aortic valve replacement in high-risk patients with a grade 4 atheroma in the ascending aorta: cerebral protection with a filter device
General Thoracic and Cardiovascular Surgery

… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

Released: 3-Mar-2022 6:00 AM EST
Cerebral Protection in TAVR—Can We Do Without? A Real-World All-Comer Intention-to-Treat Study—Impact on Stroke Rate, Length of Hospital Stay, and Twelve-Month Mortality
Journal of Personalized Medicine

… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

Released: 2-Mar-2022 8:00 AM EST
Cerebral Protection in TAVR—Can We Do Without? A Real-World All-Comer Intention-to-Treat Study—Impact on Stroke Rate, Length of Hospital Stay, and Twelve-Month Mortality
Journal of Personalized Medicine

… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

Released: 2-Mar-2022 8:00 AM EST
Operational tolerance after hematopoietic stem cell transplantation is characterized by distinct transcriptional, phenotypic, and metabolic signatures
Science Translational Medicine

… The mechanisms underlying operational tolerance after hematopoietic stem cell transplantation in humans are poorly understood. We studied two independent cohorts of patients who underwent allogeneic hematopoietic stem cell …

Released: 2-Mar-2022 8:00 AM EST
The Bumpy Road to Stem Cell Therapies: Rational Design of Surface Topographies to Dictate Stem Cell Mechanotransduction and Fate
ACS Applied Materials & Interfaces

… It then describes our current understanding of the biological mechanisms that govern the stem cell response to surface topographies and highlights specific impacts on stem cell fate. Finally, we consider the translational implications and …

Released: 2-Mar-2022 8:00 AM EST
Successful transfemoral-transcatheter aortic valve replacement in high-risk patients with a grade 4 atheroma in the ascending aorta: cerebral protection with a filter device
General Thoracic and Cardiovascular Surgery

… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …



close
0.25658