What: Conference: "Cellular and Molecular Physiology of Sodium-Calcium Exchange."

Why: The sodium-calcium (Na+/Ca2+) exchanger controls the concentration of calcium (Ca2+) ions inside cells. Ca2+ ions activate numerous physiological processes, including heart and artery contractions, neurotransmitter release, and cell division. Thus, the Na+/Ca2+ exchanger plays a central role in regulating the function of heart, brain, and circulatory systems.

The role of the Na+/Ca2+ exchanger as a contributor to human disease and its potential as a therapeutic target are only now beginning to emerge. Discussions among a gathering of international and inter-disciplinary experts will reveal how recent investigations, blending molecular biology, biochemistry, biophysics and physiology, have provided exciting answers, fueled novel themes, and provoked further questions in this intriguing field.

Proceedings from this conference will be published by the New York Academy of Science as one of their series of Annals. Volumes based on each of the prior sodium-calcium exchange meetings (1987, 1991 and 1995) have been highly cited and valuable resources.

Who: The American Physiological Society (APS). The APS was founded in 1887 to foster basic and applied science, much of it relating to human health. The Bethesda, MD-based Society has more than 10,000 members and publishes 3,800 articles in its 14 peer-reviewed journals each year.

When: October 10-14, 2001

Where: Banff, Alberta, Canada

For further information contact Donna Krupa at 703.527.7357 or at [email protected]. Or log on to http://www.the-APS.org/meetings.htm for more information about the conference.