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Dozens of Genes Associated with Autism in New Research

Two major genetic studies of autism, led in part by UC San Francisco scientists and involving more than 50 laboratories worldwide, have newly implicated dozens of genes in the disorder. The research shows that rare mutations in these genes affect communication networks in the brain and compromise fundamental biological mechanisms that govern whether, when, and how genes are activated overall.

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Changes in Scores of Genes Contribute to Autism Risk

Newfound Genetic Differences Provide Many Hints at Causes

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Education

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Autism After High School: Making the Transition

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The National Institute of Mental Health has awarded a grant to University of Kentucky College of Education Professor Lisa Ruble and a team of co-investigators to find ways to help reduce or eliminate the disconnect from needed services that often occurs when students with autism complete school.

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Mount Sinai a Lead Site in NIH-Funded Rare Diseases Consortium Studying Autism and Intellectual Disability

10-institution study seeks to pilot new treatment approaches

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UW-Milwaukee Researcher Adds to Evidence Linking Autism to Air Pollutants

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Study by Amy Kalkbrenner and colleagues shows that pollution's impact on autism rates in North Carolina is similar to results of previous pollution autism studies in California.

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Chemical Derived from Broccoli Sprouts Shows Promise in Treating Autism

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Results of a small clinical trial suggest that a chemical derived from broccoli sprouts — and best known for claims that it can help prevent certain cancers — may ease classic behavioral symptoms in those with autism spectrum disorders.

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Study Finds Link Between Neural Stem Cell Overgrowth and Autism-Like Behavior in Mice

A UCLA study shows how, in pregnant mice, inflammation, a first line defense of the immune system, can trigger an excessive division of neural stem cells that can cause “overgrowth” in the offspring’s brain, and, ultimately, autistic behavior.

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Science

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Mouse Version of an Autism Spectrum Disorder Improves When Diet Includes a Synthetic Oil

When young mice with the rodent equivalent of a rare autism spectrum disorder, called Rett syndrome, were fed a diet supplemented with the synthetic oil triheptanoin, they lived longer than mice on regular diets. Importantly, their physical and behavioral symptoms were also less severe after being on the diet.

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Social and Behavioral Sciences

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CHOP Introduces CAR Autism Roadmap™ to Help Families Navigate Autism Spectrum Disorder

The Children’s Hospital of Philadelphia's Autism Roadmap is a comprehensive, one-stop web site to help families navigate accurate, up-to-date information about autism spectrum disorder (ASD). The web site provides families customized information based on what they need- whether their child has just been diagnosed, or they’ve hit an obstacle and are looking for new ideas and resources.

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Parent Coaching Early Intervention Program Benefits Young Children with Autism

A parent coaching intervention brings meaningful benefits for preschool-aged children with autism-spectrum disorders (ASD), according to a clinical trial in the October Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

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