Heart failure patients with preserved ejection fraction (HFpEF) — where the heart becomes stiff and cannot relax or fill properly — did not have increased exercise tolerance after taking isosorbide mononitrate, compared to a placebo.
A lack of vitamin D can result in weak bones. Recent studies also show that vitamin D deficiency is linked to more serious health risks such as coronary artery disease, heart attacks, and strokes.
A new study of generally healthy men who used testosterone replacement therapy to normalize testosterone levels has found that taking supplemental testosterone does not increase their risk of experiencing a heart attack or stroke.
Jackson T. Wright Jr., MD, PhD, and researchers from University Hospitals Case Medical Center presented new results from the Systolic Blood Pressure Intervention Trial (SPRINT) showing that in patients at high risk for cardiovascular events, targeting a systolic blood pressure of less than 120 mm Hg resulted in lower rates of fatal and non-fatal major events or death compared to targeting systolic blood pressure to the usually recommended target of less than 140 mm Hg.
ISPOR 18th Annual European Congress Issue Panel 2 explored the issue of, “Possible Increased Synergy Between Health Technology Assessment (HTA) and Regulatory Agencies: Opportunity or Challenge for Medical Devices?.”
A team of researchers from the Cardiothoracic Surgical Trials Network (CTSN) found that recipients of a mitral valve replacement for Ischemic mitral regurgitation (IMR) experienced a lower rate of heart failure and fewer cardiovascular-related hospital readmissions in the two years following surgery.
A long-acting enzyme that rapidly and safely metabolizes cocaine in the blood stream is currently being investigated in animal models as a possible treatment for cocaine overdose. This research is being presented Oct. 29 at the 2015 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, the world’s largest pharmaceutical sciences meeting in Orlando, Fla. Oct. 25–29.
ISPOR 18th Annual European Congress Issue Panel 1 explored, “What Is the Role of Economic Evaluation in Pricing and Reimbursement of Medicines: A Comparison Between England, Germany, and France.”
ISPOR's 18th Annual European Congress first plenary session — Strategy in Motion: The Current and Future Lifecycle Approach to Decision Making on Health Technologies — was held this morning at the MiCo – Milano Congressi in Milan, Italy.
The blood-brain barrier has been non-invasively opened in a patient for the first time. A team at Sunnybrook Health Sciences Centre in Toronto used focused ultrasound to enable temporary and targeted opening of the blood-brain barrier (BBB), allowing the more effective delivery of chemotherapy into a patient’s malignant brain tumor.
Bryan Martin, DO, Columbus, Ohio, was installed as president of the American College of Allergy, Asthma and Immunology (ACAAI) at the ACAAI Annual Scientific Meeting in San Antonio on Nov. 9. Stephen A. Tilles, MD, Seattle WA, was elected ACAAI president-elect.
Researchers at Hospital for Special Surgery have identified multiple clinical and biologic markers that correlate with adverse pregnancies, including, most recently, the activation of complement, a series of proteins that protect us from invading microbes.
Findings from a new study conducted by researchers from Hospital for Special Surgery suggest that lower socioeconomic status at the community level significantly increases the risk of pain and poor function following a knee replacement.
Chronic Kidney Disease (CKD), which afflicts more than 26 million Americans, is a condition in which individuals experience a slow loss of kidney function over time. At the American Heart Association Scientific Sessions 2015, researchers from the Perelman School of Medicine at the University of Pennsylvania will present findings from their analysis of the Chronic Renal Insufficiently Cohort (CRIC) study to evaluate risk markers for adverse cardiac events in patients with CKD.
People with heart problems often have diabetes, which puts them at greater risk for heart attacks, heart failure and stroke. Now, a new study has found that ensuring heart attack patients are promptly diagnosed and treated for diabetes makes a significant difference in improving their cardiac outcomes.
In an attempt to correct defects in the energy generation that contributes to poor pump function among heart failure patients, researchers examined whether the diabetes drug liraglutide, could improve the condition of patients with advanced heart failure. Despite improvements in blood sugar control, the therapy did not improve the clinical stability or pumping action of the heart in patients with advanced heart failure. Kenneth B. Margulies, MD, a professor of Medicine and research director for Heart Failure and Transplantation in the Perelman School of Medicine at the University of Pennsylvania, presented data from the Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT) study at the American Heart Association Scientific Sessions 2015.
People with heart disease face an increased risk of a serious heart attack during poor air quality days, according to a major new study presented today (Sunday, Nov. 8) at the American Heart Association Scientific Session in Orlando.
Using a video to train family members of patients at risk for cardiac arrest in CPR may be just as effective as using the traditional hands-on method with a manikin, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The findings suggest simplified and more cost-effective approaches may be useful for disseminating CPR education to families of at-risk patients and the general public. The results are being presented during the American Heart Association Scientific Sessions 2015.
Researchers have found that the recurrence of atrial fibrillation increases in patients who are overweight and decreases when patients are able to lose weight, and keep it off, following a cardiac ablation, according to two new studies.
Injecting ozone gas into the knee reduces pain and improves functioning and quality of life in people with knee osteoarthritis, according to research presented this week at the American College of Rheumatology Annual Meeting in San Francisco
Massive weight loss following bariatric (weight loss) surgery has the potential to greatly improve the quality of life for patients suffering from osteoarthritis, according to research presented this week at the American College of Rheumatology Annual Meeting in San Francisco.
People with well-controlled rheumatoid arthritis who change anti-TNF inhibitors due to non-medical reasons — such as increased copay, change of insurance, job loss, or other economic factors — are at a higher risk to develop increased symptoms and higher disease activity as well as an increased utilization of health care resource use, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Francisco.
Injections of corticosteroids in the knee joints appear to be safe, but not effective, according to the findings of a two-year clinical trial presented this week at the American College of Rheumatology Annual Meeting in San Francisco.
Mycophenolate mofitil is as effective as cyclophosphamide in treating interstitial lung disease in people with scleroderma, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Francisco.
People diagnosed with rheumatoid arthritis after the year 2000 don’t have as much of an increased risk of death as people diagnosed before 2000, according to research presented this week at the American College of Rheumatology Annual Meeting in San Francisco. This, suggests the researchers involved in the study, is likely due to better treatments that focus on eradicating inflammation – a major contributor to the increased risk of death in RA
Two studies, presented this week at the American College of Rheumatology Annual Meeting in San Francisco, show a person’s diet can significantly affect his or her chance of developing rheumatoid arthritis.
Anikinra may offer hope for rheumatology patients with the heart condition
The presence of tophi – crystal deposits of uric acid found on the surface of the joints or in the skin and cartilage – in people with gout can increase their risk of developing cardiovascular disease, according to research presented this week at the American College of Rheumatology Annual Meeting in San Francisco.
A new study, presented this week at the American College of Rheumatology Annual Meeting in San Francisco, shows certain fractures due to osteoporosis can cause premature death in people 45 and older. This is the largest study, to date, that shows a connection between these fractures and premature death.
Being overweight or obese can reduce the likelihood of achieving sustained remission of early rheumatoid arthritis, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Francisco.
A new study, presented this week at the American College of Rheumatology Annual Meeting in San Francisco, shows that treating rheumatoid arthritis patients toward a target of remission or low disease activity works immediately and leads to higher remission rates.
Cardiovascular disease deaths are declining in people who have been diagnosed with rheumatoid arthritis after the year 2000, according to research presented this week at the American College of Rheumatology Annual Meeting in San Francisco. This decline is found when compared to people diagnosed with RA in previous decades as well as when compared to people without the disease – signifying an encouraging milestone.
A diagnosis of arthritis in a baby boomer doesn’t mean that person should exit the workforce. Two studies, presented this week at the American College of Rheumatology Annual Meeting in San Francisco, show this growing group often returns to work after retirement and takes little advantage of workplace accommodations for their disease.
Resistance strength training reduces pain and increases function and treatment satisfaction in people with hand osteoarthritis, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Francisco.
A study at Hospital for Special Surgery finds that a support group addressing the psychological and educational needs of people with lupus is a valuable resource to help them cope with the disease.
A new study by a group at Hospital for Special Surgery reveals that blacks in the U.S. are at a significantly higher risk of requiring a revision than American whites, and that socioeconomic factors may play an important role in revision risk.
Excessive weight loss aided by bariatric (weight loss) surgery has been linked to improved symptoms in people with psoriasis and psoriatic arthritis, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Francisco.
Both Tai Chi and physical therapy positively impact pain, function and other symptoms of knee osteoarthritis – making Tai Chi a viable treatment alternative for people suffering with the degenerative disease, according to research presented this week at the American College of Rheumatology Annual Meeting in San Francisco.
Using a pedometer to measure the number of steps one takes in a day has been linked to lower fatigue in persons with rheumatoid arthritis, according to research presented this week at the American College of Rheumatology Annual Meeting in San Francisco.
Mechanical CPR, in which a device is used by Emergency Medical Service (EMS) providers to deliver automated chest compressions during cardiac arrest resuscitation care, is associated with an equivalent survival rate for patients experiencing cardiac arrest outside of the hospital as manual CPR, according to new findings from a team of researchers at the Perelman School of Medicine at the University of Pennsylvania. The study is the first large scale, real-world proof that mechanical CPR may be an equivalent alternative to manual CPR for treating patients experiencing extensive cardiac arrest episodes and requiring advanced life support services. The results are being presented during the American Heart Association Scientific Sessions.
The homes of urban African Americans with uncontrolled hypertension were often lacking either foods or needed appliances required for meals consistent with the Dietary Approaches to Stop Hypertension (DASH) diet. While African Americans with uncontrolled hypertension often had discussions with their physicians about diet, few discussions were related to the DASH diet. Research that uncovered these dietary concerns will be presented at ASN Kidney Week 2015 November 3–8 at the San Diego Convention Center in San Diego, CA.
African American, Native American, and Asian dialysis patients were 43% to 44% less likely than whites to use hospice before dying. Research that uncovered these disparities will be presented at ASN Kidney Week 2015 November 3–8 at the San Diego Convention Center in San Diego, CA.
Kidneys that would normally be made available for transplantation were less likely to be procured from donors over the weekend, and organs procured during the weekend were more likely to be discarded than kidneys procured on other days. The findings, which should influence future policy aimed at improving kidney transplantation rates, will be presented at ASN Kidney Week 2015 November 3–8 at the San Diego Convention Center in San Diego, CA.
Australian patients with kidney disease who require hemodialysis can travel and not miss their lifesaving dialysis treatments thanks to a new holiday dialysis program created in partnership by Kidney Health Australia and Monash Health. Results from a study of the Big Red Kidney Bus program will be presented at ASN Kidney Week 2015 November 3–8 at the San Diego Convention Center in San Diego, CA.
New research indicates that the prevalence of chronic kidney disease (CKD) in the United States has stabilized overall. Analysis of the latest NHANES data is consistent with the recent plateau in the number of new patients with end-stage renal disease. The study indicates the need for continued efforts to protect Americans’ kidney health and will be presented at ASN Kidney Week 2015 November 3–8 at the San Diego Convention Center in San Diego, CA.
The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented at ASN Kidney Week 2015 November 3–8 at the San Diego Convention Center in San Diego, CA.
For the first time, chondroitin sulfate has been more successful than celecoxib in reducing the long-term progression of knee osteoarthritis (OA), according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Francisco.
Increasing median income levels of transplant candidates’ zip codes were associated with higher rates of living donation, but African American candidates living in the wealthiest neighborhoods had only slightly higher rates than rates seen among the lowest median income areas for Caucasians. African American donors had higher rates of complications early after donation. The findings will be presented at ASN Kidney Week 2015 November 3–8 at the San Diego Convention Center in San Diego, CA.
Adults with kidney failure benefit from cadaveric kidney transplants from infants and toddlers when adult organs are unavailable. The findings will be presented at ASN Kidney Week 2015 November 3–8 at the San Diego Convention Center in San Diego, CA.
Compared with recipients of living related kidney donor transplants, recipients who purchased organs internationally were more likely to develop hepatitis C, hepatitis B, and cytomegalovirus, and they were more likely to experience acute and recurrent rejections and surgical complications. Patient and organ survival rates were also lower in “commercial” recipients. Research that uncovered these risks associated with transplant tourism will be presented at ASN Kidney Week 2015 November 3–8 at the San Diego Convention Center in San Diego, CA.
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