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Medicine

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Human Eye, Chickens, Daylight vision, Retina, Eye Sight, Fovea, High Acuity Spot, Stem Cell, Connie Cepko, HMS, Harvard Medical School, Susana da Silva, Vitamin A, Retinoic Acid

Bird’s Eye Perspective

Chickens may illuminate how humans developed sharp daylight vision

Medicine

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Alzheimber's Disease, Beth Israel Deaconess Medical Center, Neuroscience

Anti-Epilepsy Drug Restores Normal Brain Activity in Mild Alzheimer’s Disease

In a recent feasibility study, BIDMC tested an anti-epileptic drug for its potential impact on the brain activity of patients with mild Alzheimer’s disease. The team documented changes in patients’ EEGs that suggest the drug could have a beneficial effect.

Medicine

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Anti-obesity Hormone, Leptin, Hormone Leptin, Protein, Obesity, Cell Metabolism, HMS, Harvard Medical School, Jeffrey Flier, Eleftheria Maratos-Flier, Starvation, Metabolism, obesity gene, Biology, Body Weight

Does the Emperor Have Clothes?

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Decades after the discovery of anti-obesity hormone, scant evidence that leptin keeps lean people lean, scientists caution

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Dry eye disease

David A. Sullivan, M.S., PH.D., FARVO, Receives the American Optometric Association’s Dr. Donald R. Korb Award for Excellence

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David A. Sullivan, M.S., Ph.D., FARVO, Senior Scientist at Schepens Eye Research Institute of Massachusetts Eye and Ear and Associate Professor of Ophthalmology at Harvard Medical School is the recipient of the 2017 Dr. Donald R. Korb Award for Excellence, the highest honor given by the Contact Lens and Cornea Section of the American Optometric Association (AOA).

Medicine

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Alzheimer's Disease, Microglia, Genetics, Immune Cell

A Single Microglial Protein Controls Suite of Alzheimer’s Risk Genes

The discovery hints that microglia, rather than neurons, may control much of a person’s genetic susceptibility to Alzheimer’s disease.

Medicine

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Lasik, Myopia, Nearsightedness

Mass. Eye and Ear Specialists Perform First SMILE Procedures to Correct Nearsightedness

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Ophthalmologists at Massachusetts Eye and Ear are now offering a new type of minimally-invasive laser vision correction, the ReLEx® SMILE procedure.

Medicine

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Alzheimer's Disease, Amyloid, Amyloid Beta

More Support for Amyloid Hypothesis in Alzheimer's: Protective APP Mutation Lowers Aβ in Blood

A new study shows that people with a protective Aβ mutation have less of the peptide in their blood all through their lives, likely explaining why they do not get Alzheimer's. It suggests ways to prevent the disease in the vast majority of people who don’t have the mutation.

Science

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Developmental Biology And Molecular Biology, Whitehead Institute, Terry Orr-Weaver, Embryo Development, mRNA translation

Elegant Switch Controls Translation in Transition From Egg to Embryo

The transition from an egg to a developing embryo is one of life’s most remarkable transformations. Now Whitehead Institute researchers have used fruit flies to decipher how one aspect—control of the translation of messenger RNAs (mRNAs) into proteins—shifts as the egg becomes an the embryo. This type of switch could tell scientists more about how human cells work and embryos develop.

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Scientists Reveal a Key Link Between Brain Circuits Governing Hunger and Cravings

By developing a new approach to imaging and manipulating particular groups of neurons in the mouse brain, scientists at Beth Israel Deaconess Medical Center (BIDMC) have identified a pathway by which neurons governing feelings of hunger influence distant neurons involved in the decision of whether or not to react to food-related cues. Their findings could open the door to targeted therapies that dampen food cue-evoked cravings in people with obesity. The research was published online today in the journal Nature.

Medicine

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Lloyd Paul Aiello, M.D., Ph.D., Receives the 2017 JDRF Excellence in Clinical Research Award for Type 1 Diabetes Research

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The award recognizes Aiello's research to determine the underlying biochemistry and molecular mechanisms of diabetic retinopathies, then develop and test novel therapeutic interventions through rigorous translational and clinical trial research.







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