Feature Channels: Stem Cells

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Released: 18-Oct-2022 12:00 PM EDT
Ostrich Eggshell – Hydroxyapatite Composite as a Safe Scaffold with Osteoinductive Properties
Preprints

Farideh Alahgahi, Esmail Fattahi, Mohsen Saeidi, Mir Mahmoud Mortazavi

Released: 17-Oct-2022 12:00 PM EDT
MicroRNAs 7/17/155 As A Potential Breast Tumor Stemness miRNA Cluster: Detection of Breast Cancer Grade Specific miRNA-mRNA Interaction Network Inspiration from Mammary Gland Development
Preprints

Saeed Khodayari, Hamid Khodayari, Haniyeh Jallali, Elnaz Saeedi, Ali Faryabi, Meghdad Yeganeh, Ahad Mohammadnejad, Amirnader Emami Razavi, Mohammad Dashtkoohi, Farimah Hadjilooei, Reza Shirkoohi, Ramesh Omranipour, Karim Nayernia, Habibollah Mahmoodzadeh

Released: 17-Oct-2022 12:00 PM EDT
Development of a highly sensitive immunoassay to measure ataxin2 as a target engagement marker in Spinocerebellar Ataxia Type 2
Preprints

Jessica Bux, Nesli Ece Sen, Isa-Maria Klink, Stefan Hauser, Ludger Schöls, Georg Auburger, Olaf Horst Riess, Jeannette Hübener-Schmid

Released: 17-Oct-2022 12:00 PM EDT
Human organoid model of PCH2a recapitulates brain region-specific pathology
Preprints

Theresa Kagermeier, Stefan Hauser, Kseniia Sarieva, Lucia Laugwitz, Samuel Groeschel, Wibke Janzarik, Zeynep Yentuer, Katharina Becker, Ludger Schoels, Ingeborg Kraegeloh-Mann, Simone Mayer

Released: 17-Oct-2022 12:00 PM EDT
Leak current, even with gigaohm seals, can cause misinterpretation of stem cell-derived cardiomyocyte action potential recordings
Preprints

Alexander Phillip Clark, Michael Clerx, Siyu Wei, Chon Lok Lei, Teun de Boer, Gary R Mirams, David J Christini, Trine Krogh-Madsen

Released: 17-Oct-2022 12:00 PM EDT
Mitochondrial complex I controls blood brain barrier permeability
Preprints

Gavin M Davis, Estelle Juere, Jerrard M Hayes, Gavin P Davey

Released: 17-Oct-2022 12:00 PM EDT
Type 2 Inflammation Drives an Airway Basal Stem Cell Program Through Insulin Receptor Substrate Signaling
Preprints

Xin Wang, Nils Hallen, Minkyu Lee, Sachin Samuchiwal, Qihua Ye, Kathleen Buchheit, Alice Maxfield, Rachel Roditi, Regan Bergmark, Neil Bhattacharyya, Tessa Ryan, Deb Gakpo, Soumya Raychaudhuri, Dan Dwyer,

Released: 17-Oct-2022 12:00 PM EDT
Single-cell Landscape Analysis of the Circulating Human B Cell Pool under Selective Pressure of Allogeneic Stem Cell Transplantation
Preprints

Jonathan C Poe, Jiyuan Fang, Dadong Zhang, Marissa R Lee, Rachel A DiCioccio, Hsuan Su, Xiaodi Qin, Jennifer Zhang, Jonathan Visentin, Sonali J Bracken, Vincent T Ho, Kathy S Wang, Jeremy J Rose, Steven Z Pavletic,

Released: 17-Oct-2022 12:00 PM EDT
Poly(ε-caprolactone)-based nanofibrous scaffold incorporated with decellularized bone extracellular matrix as a potential strategy for bone regeneration
Preprints

Ming Zhang, Quan Zhou, Qiangsheng Dong, Jue Zhang, Xin Zhou, Hao Huang, Junchen Bao, Hongjian Shan, Furong Sun, Liangliang Li

Released: 14-Oct-2022 12:00 PM EDT
Predictive nonlinear modeling of malignant myelopoiesis and tyrosine kinase inhibitor therapy
Preprints

Jonathan Dennis Rodriguez, Abdon Iniguez, Nilamani Jena, Prasanthi Tata, Joan Liu, Arthur D Lander, John Lowengrub, Richard Van Etten

Released: 14-Oct-2022 12:00 PM EDT
A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals
Preprints

Jorge Lazaro, Maria Costanzo, Marina Sanaki-Matsumiya, Charles Girardot, Masafumi Hayashi, Katsuhiko Hayashi, Sebastian Diecke, Thomas B Hildebrandt, Giovanna Lazzari, Jun Wu, Stoyan G Petkov, Rudiger Behr, Vikas Trivedi, Mitsuhiro M

Released: 14-Oct-2022 12:00 PM EDT
Machine-guided cell-fate engineering
Preprints

Evan M Appleton, Jenhan Tao, Gregory J Fonseca, Songlei Liu, Christopher H Glass, George M Church

Released: 14-Oct-2022 12:00 PM EDT
An integrated cell barcoding and computational analysis pipeline for scalable analysis of differentiation at single-cell resolution
Preprints

Sophie Shen, Tessa Werner, Yuliangzi Sun, Woo Jun Shim, Samuel Lukowski, Stacey Andersen, Han Sheng Chiu, Di Xia, Xiaoli Chen, Duy Pham, Zezhuo Su, Joseph E Powell, Patrick P. L. Tam, Mikael Boden,

Released: 14-Oct-2022 12:00 PM EDT
Gamma Irradiation Processing on 3D PCL Devices - A Preliminary Biocompatibility Assessment
Preprints

Fernando Guedes, Mariana V. Branquinho, Sara Biscaia, Rui D. Alvites, Ana C. Sousa, Bruna Lopes, Patrícia Sousa, Alexandra Rêma, Irina Amorim, Fátima Faria, Tatiana M. Patrício, António Bugalho, Nuno Alves, Ana C. Maurício

Released: 13-Oct-2022 12:00 PM EDT
Surgical efficacy and quality of wide resection of the pelvic peritoneum in patients with epithelial ovarian cancer
Preprints

Akiho Nishimura, Takeshi Motohara, Jun Morinaga, Yutaka Iwagoi, Mayuko Yamamoto, Munekage Yamaguchi, Yo Miyahara, Hironori Tashiro, Hidetaka Katabuchi

Released: 13-Oct-2022 12:00 PM EDT
HDAC8-mediated inhibition of EP300 drives a neural crest-like transcriptional state that increases melanoma brain metastasis
Preprints

Michael F Emmons, Richard L Bennett, Alberto Riva, Chao Zhang, Robert Macaulay, Daphne Dupere-Richer, Bin Fang, Edward Seto, John Koomen, Jiannong Li, Ann Chen, Peter Forsyth, Jonathan Licht, Keiran S.M. Smalley

Released: 13-Oct-2022 12:00 PM EDT
Use of high-plex data reveals novel insights into the tumour microenvironment of clear cell renal cell carcinoma
Preprints

Raffaele De Filippis, Georg Wolflein, In Hwa Um, Peter D Caie, Sarah Warren, Andrew White, Elizabeth Suen, Emily To, Ognjen Arandjelovic, David J Harrison

Released: 13-Oct-2022 12:00 PM EDT
Concurrent temporal patterning of neural stem cells in the fly visual system
Preprints

Urfa Arain, Ishrat Maliha Islam, Priscilla Valentino, Ted Erclik

Released: 13-Oct-2022 12:00 PM EDT
Advanced physiological maturation of iPSC-derived human cardiomyocytes using an algorithm-directed optimization of defined media components
Preprints

Neal I. Callaghan, Lauren J. Durland, Wenliang Chen, Uros Kuzmanov, Maria Zena Miranda, Zahra Mirzaei, Ronald G. Ireland, Erika Yan Wang, Karl Wagner, Michelle M. Kim, Julie Audet, Paul Santerre, Anthony O. Gramolini, Filio Billia,

Released: 12-Oct-2022 12:00 PM EDT
Treatment of herpes zoster with brivudin in immunocompromised children
Preprints

Clara Vogel, Laura Wetzel, Peter Wutzler, Bernd Gruhn

Released: 12-Oct-2022 12:00 PM EDT
An Anti-EpCAM Monoclonal Antibody (EpMab-37-mG2a-f) Exerts Antitumor Activity against Breast Cancer in Mouse Xenograft Model
Preprints

Teizo Asano, Hiroyuki Suzuki, Guanjie Li, Tomokazu Ohishi, Manabu Kawada, Takeo Yoshikawa, Tomohiro Tanaka, Mika K. Kaneko, Yukinari Kato

Released: 12-Oct-2022 12:00 PM EDT
Temporal Evolution and Differential Patterns of Cellular Reconstitution after Therapy for Childhood Cancers
Preprints

Gina Hofmann, Jakob Zierk, Bettina Sobik, Zofia Wotschofsky, Stephanie Sembill, Manuela Krumbholz, Markus Metzler, Axel Karow

Released: 12-Oct-2022 12:00 PM EDT
Trophoblast stem-cell-derived exosomes alleviate cardiotoxicity of Doxorubicin via improving Mfn2-mediated mitochondrial fusion
Preprints

Junfeng Duan, Xiaoli Liu, Song Shen, Xi Tan, Yi Wang, Lian Wang, Lina Kang, Kun Wang, Zhonghai Wei, Yu Qi, Lei Hu, Biao Xu, Rong Gu

Released: 12-Oct-2022 12:00 PM EDT
Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs
Preprints

Dulce Lima Cunha, Jonathan Eintracht, Philippa Harding, Jo Huiqing Zhou, Mariya Moosajee

Newswise:Video Embedded second-patient-to-receive-a-first-of-its-kind-surgery
VIDEO
Released: 11-Oct-2022 12:05 PM EDT
Second patient to receive a first-of-its-kind surgery
UC Davis Health (Defunct)

Michelle and Jeff were excited to build their new family together, but when she received the distressing news that her developing baby was diagnosed with spina bifida, she looked for the best treatment. She was referred to the world’s first stem cell clinical trial.

Released: 11-Oct-2022 12:00 PM EDT
Robust Advanced Modeling and Scheduling System (RAMS): From Space Exploration to Real-World Biomanufacturing
Preprints

Michael Saint-Guillain, Isabelle Sansdrap, Michaël Brion, Eric Pauly

Released: 10-Oct-2022 12:00 PM EDT
The MYC-YBX1 Circuit in Maintaining Stem-like Vincristine-Resistant Cells in Rhabdomyosarcoma
Preprints

Madeline Fritzke, Kenian Chen, Weiliang Tang, Spencer Stinson, Misa Ito, Lin Xu, Eleanor Chen

Released: 10-Oct-2022 12:00 PM EDT
Human endometrium derived induced pluripotent stem cells are amenable to directed erythroid differentiation
Preprints

Hyun Kyung Kim, Si Hyun Cho, Young Sik Choi, Byung Seok Lee, Sinyoung Kim, Joo Hyun Park

Released: 10-Oct-2022 12:00 PM EDT
Aβ42 treatment of the brain side reduced the level of flotillin from endothelial cells on the blood side via FGF-2 signaling in a blood-brain barrier model
Preprints

Tomohisa Nakamura, Tadahiro Hashita, Yuxin Chen, Yuan Gao, Yan Sun, Sadequl Islam, Hiroyuki Sato, Yasuyuki Shibuya, Kun Zou, Tamihide Matsunaga, Makoto Michikawa

Released: 10-Oct-2022 12:00 PM EDT
PRAMEL7/CUL2 axis regulates NuRD stability to establish ground-state pluripotency in embryonic stem cells
Preprints

Meneka Rupasinghe, Cristiana Bersaglieri, Deena M. Leslie Pedrioli, Patrick G.A. Pedrioli, Michael O. Hottiger, Paolo Cinelli, Raffaella Santoro

Released: 10-Oct-2022 12:00 PM EDT
The neuroprotective effects of dental pulp stem cells and erythropoietin in mice hippocampus after ischemia-reperfusion
Preprints

Shahram Mohammad Poor, Amir Johari Moghadam, Ameneh Rezayof, Rana Mehdizade, Mohammad Barbarestani, Rafieh Alizadeh, Naser Abbasi, Majid Katebi, Mansoureh Soleimani

Released: 10-Oct-2022 12:00 PM EDT
Matrix Protein Tenascin-C Promotes Kidney Fibrosis via STAT3 activation in Response to Tubular Injury
Preprints

Chuanming Hao, Qionghong Xie, Min Zhang, Xiaoyi Mao, Mingyue Xu, Shaojun Liu, Da Shang, Yunyu Xu, Ruiying Chen, Yi Guan, Xinzhong Huang, Roy Zent, Ambra Pozzi

Released: 10-Oct-2022 12:00 PM EDT
The Viral Load of Human Cytomegalovirus Infection in Children Following Hematopoietic Stem Cell Transplant by Chip Digital PCR
Preprints

Wen-Jun Wang, Miao Feng, Feng- He, Juan Song, Qin-Qin Song, Dong Xia, Rong Liu, Hai-Lan Yao, Jun Han

Released: 10-Oct-2022 12:00 PM EDT
A cell size threshold triggers commitment to stomatal fate in Arabidopsis
Preprints

Yan Gong, Renee Dale, Hannah F Fung, Gabriel O Amador, Margot Smit, Dominique Bergmann

Released: 10-Oct-2022 12:00 PM EDT
UTX inhibition suppresses proliferation and promotes apoptosis in patient-derived glioblastoma stem cells by modulating periostin expression
Preprints

Yan Luan, Yingfei Liu, Jingwen Xue, Ke Wang, Kaige Ma, Haixia Lu, Xinlin Chen, Yong Liu, Zhichao Zhang

Released: 9-Oct-2022 12:00 PM EDT
2,4-Di-tert-butylphenol Induces Adipogenesis in Human Mesenchymal Stem Cells by Activating Retinoid X Receptors
Preprints

Xiao-Min Ren, Richard C Chang, Yikai Huang, Angélica Amorim Amato, Coralie Carivenc, Marina Grimaldi, Angela Y Kuo, Patrick Balaguer, William Bourguet, Bruce Blumberg



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