A report by the first Lancet Commission on Dementia Prevention and Care identifies powerful tools to prevent dementia and touts the benefits of nonmedical interventions for people with dementia.
A new study led by researchers at Washington University School of Medicine in St. Louis suggests that measures of amyloid beta in the blood have the potential to help identify people with altered levels of amyloid in their brains or cerebrospinal fluid. Currently, the only way to detect amyloid beta in the brain is via PET scanning or a spinal tap.
Emergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at Rush University Medical Center. The results of their study suggest that hospitalization may be a more of a major risk factor for long-term cognitive decline in older adults than previously recognized.
Three new gene variants, found in a genome wide association study of Alzheimer’s disease (AD), point to the brain’s immune cells in the onset of the disorder. These genes encode three proteins that are found in microglia, cells that are part of the brain’s injury response system.
Researchers have found cell receptors abnormally overexpressed in post-mortem brains of those with Parkinson’s and Alzheimer’s diseases, and that they can be inhibited in animal models to clear toxic protein buildup, reduce brain inflammation, and improve cognitive performance.
Depending on what generation you belong to, the term “improvisational dance” may conjure up images of beatniks grooving to the beat of bongos in a darkened coffeehouse or the black-clad Dieter gyrating to techno pop in a Sprockets sketch on “Saturday Night Live”.
Anyone can learn whether they carry mutations known to cause Alzheimer’s, frontotemporal dementia, and other fatal neurodegenerative diseases.
Research from Washington University School of Medicine in St. Louis, Radboud University Medical Centre in the Netherlands, and Stanford University shows that disrupting just one night of sleep in healthy, middle-aged adults causes an increase in a brain protein associated with Alzheimer’s disease. Further, a week of poor sleep leads to an increase in another brain protein that has been linked to brain damage in Alzheimer’s and other neurological diseases.
Poor sleep may be a sign that people who are otherwise healthy may be more at risk of developing Alzheimer’s disease later in life than people who do not have sleep problems, according to a study published in the July 5, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers have found a link between sleep disturbances and biological markers for Alzheimer’s disease found in the spinal fluid.
New research by scientists at the MRC Laboratory of Molecular Biology in the United Kingdom and Indiana University School of Medicine gives the most detailed view yet of tau protein structures found in Alzheimer’s disease.
Saint Louis University researchers have received a $443,636 grant from the National Institute on Aging to investigate the relationship between the diabetes drug Metformin and dementia risk.
While often used interchangeably, dementia and Alzheimer’s disease are not the same.
The connection between slowed walking speed and declining mental acuity appears to arise in the right hippocampus, a finger-shaped region buried deep in the brain at ear-level, according to a 14-year study conducted by scientists at the University of Pittsburgh Graduate School of Public Health.
Faculty, staff and graduate students are taking on one of society’s most vexing health challenges: how to prevent or slow the onset of dementia through changes in diet and exercise. And what sets the Lifestyle Interventions Group apart is its inclusion of disciplines beyond the typical confines of brain science.
Patients can engage with the Ambient Activity Technology device any time to view family photos, hear their favorite music, and play games.
Mount Sinai researchers find this network central to Alzheimer’s disease susceptibility
In a recent feasibility study, BIDMC tested an anti-epileptic drug for its potential impact on the brain activity of patients with mild Alzheimer’s disease. The team documented changes in patients’ EEGs that suggest the drug could have a beneficial effect.
Going for a walk outside, reading, listening to music—these and other enjoyable activities can reduce blood pressure for elderly caregivers of spouses with Alzheimer’s disease, suggests a study in Psychosomatic Medicine: Journal of Biobehavioral Medicine, the official journal of the American Psychosomatic Society. The journal is published by Wolters Kluwer.
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