Feature Channels: Infectious Diseases

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Advanced technologies have been used to solve a long-standing mystery about why some people develop serious illness when they are infected with the malaria parasite, while others carry the infection asymptomatically.

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As the SARS-CoV-2 virus that causes COVID-19 continues to evolve, immunologists and infectious diseases experts are eager to know whether new variants are resistant to the human antibodies that recognized initial versions of the virus.

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Adults and children with COVID-19 who have a history of malnutrition may have an increased likelihood of death and the need for mechanical ventilation, according to a study published in Scientific Reports.

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The UCLA Fielding School of Public Health's WORLD Policy Analysis Center (WORLD) released the first study to systematically analyze how common sick leave eligibility criteria in the U.S. affect access and to examine sick leave policies globally to understand whether these criteria are necessary. The research found marked racial and gender gaps in leave access in the U.S. due to restrictions targeting workers at small businesses, part-time workers, and workers at new jobs.

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In a new study, published recently in the journal Circulation Research, scientists discover how the production of protective molecules known as specialised pro-resolving mediators (SPM) is altered in patients with COVID-19.

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许多人会利用国家法定假日出门旅行或举办聚会。由于仍有许多人需要接种COVID-19疫苗以及传染性更强的Delta变种疫苗，因此健康专家建议，如果您计划旅行或召集很多人聚会，请务必谨慎。

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Researchers at Cornell have developed a way to analyze how individual immune cells react to the bacteria that cause tuberculosis. It could pave the way for new vaccine strategies and provide insights into fighting other infectious diseases.

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Although in-school transmission of COVID-19 among K-12 students is low when safeguards are in place, the risk of acquiring COVID-19 during school bus transportation is unclear.

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Durante la temporada vacacional del país, muchas personas viajan o hacen fiestas, pero como aún falta vacunar contra la COVID-19 a mucha gente y circula por allí la variante Delta más contagiosa, los expertos en salud recomiendan ser cautelosos al planificar viajes o reuniones con grupos grandes de personas.

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Feriados nacionais são eventos em que muitas pessoas viajam ou dão festas. Com muitas pessoas ainda sendo vacinadas contra a COVID-19 e com a circulação da variante Delta, que é mais contagiosa, os especialistas recomendam cuidado ao planejar uma viagem ou reunir um grande grupo de pessoas.

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SARS-CoV-2 still poses major challenges to mankind. The frequent emergence of mutant forms makes the threat posed by the virus difficult to predict.

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In a large observational study, Mayo Clinic researchers have shown that two monoclonal antibodies administered separately helped prevent hospitalization in high-risk patients who became infected with COVID-19. The study also showed more hospitalizations were observed among patients with more comorbidities. The findings appear in The Journal of Infectious Diseases.

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Natto, a fermented soybean dish often served for breakfast in Japan, originated at the turn of the last millennium but may hold an answer to a modern problem: COVID-19, according to a new study based on cell cultures.

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Researchers are the first to model COVID-19 completion versus cessation in clinical trials using machine learning algorithms and ensemble learning. They collected 4,441 COVID-19 trials from ClinicalTrials.gov to build a testbed with 693 dimensional features created to represent each clinical trial. These computational methods can predict whether a COVID-19 clinical trial will be completed or terminated, withdrawn or suspended. Stakeholders can leverage the predictions to plan resources, reduce costs, and minimize the time of the clinical study.

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With California state vaccination rates slowing, and guidelines on mask wearing and social gatherings changing, the UCLA Center for Health Policy Research (CHPR) has released new data from the 2021 California Health Interview Survey (CHIS) that sheds light on Californians’ views on getting the vaccine and following suggested safety protocols.

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Starting the COVID-19 vaccination process in July and August can prepare teens and young adults for a safe school year and protect children who can’t be vaccinated.

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Scientific evidence strongly supports that SARS-CoV-2, the virus that causes the COVID-19 disease, occurred when a virus circulating in animals transferred to humans, according to a commentary publishing in the August edition of ASA Monitor, the official news publication of the American Society of Anesthesiologists.

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Using data from 9,859 COVID-19 infections, Mayo Clinic researchers have new insights into risk factors for younger populations, some of which differ significantly from their older counterparts. People younger than 45 had a greater than threefold increased risk of severe infection if they had cancer or heart disease, or blood, neurologic or endocrine disorders, the research found. These associations were weaker in older age groups. The study was published in Mayo Clinic Proceedings.

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Researchers at Michigan Medicine have discovered another functional autoantibody in COVID-19 patients that contributes to the disease’s development and the “firestorm” of blood clots and inflammation it induces. The autoantibody makes it harder for the body to degrade neutrophil extracellular traps, the toxic webs of DNA and proteins produced by overactive immune cells at heightened levels in COVID patients.