Identification of the Metaphyseal Skeletal Stem Cell
PreprintsGuan Yang, Qi He, Xiaoxiao Guo, Rong-Yu Li, Jingting Lin, Wanyu Tao, Wenjia Liu, Huisang Lin, Mingchuan Tang, Shilai Xing, Yini Qi, Yanli Peng, Lei Dong, Jing-Dong J Han, Bin
Guan Yang, Qi He, Xiaoxiao Guo, Rong-Yu Li, Jingting Lin, Wanyu Tao, Wenjia Liu, Huisang Lin, Mingchuan Tang, Shilai Xing, Yini Qi, Yanli Peng, Lei Dong, Jing-Dong J Han, Bin
Iwo Kucinski, Joana Campos, Melania Barile, Francesco Severi, Natacha Bohin, Pedro N Moreira, Lewis Allen, Hannah Lawson, Myriam L R Haltalli, Sarah J Kinston, Dónal O'Carroll, Kamil R Kranc, Berthold Göttgens
The latest research and expert commentary on pain management.
A new University of California, Irvine-led study reveals how mechanical forces and tissue mechanics influence the morphology of the developing brain, and establishes a direct link in neural stem cells between Piezo1, a mechanically-activated ion channel, and intracellular cholesterol levels during neural development.
Dorota Piekna-Przybylska, Daxiang Na, Jingyuan Zhang, Cameron Baker, John Ashton, Patricia White
Sophie Domingues, Annabelle Darle, Yolande Masson, Manoubia Saidani, Emilie Lagoutte, Ana Bejanariu, Julien Coutier, Raif Eren Ayata, Marielle Bouschbacher, Marc Peschanski, Lemaitre Gilles, Christine Baldeschi
Xiangling Meng, David Yao, Kevin W Kelley, Noah Reis, Mayuri V Thete, Shravanti Kulkarni, Michael C Bassik, Sergiu P Pasca
Rachel Jacques, Bo Zhou, Emilie Marhuenda, Jon Gorecki, Anirban Das, Thomas Iskratsch, Steffi Krause
Changlong Jin, Yanqin Ju, Shouliang Zhao, Han Xie
Suyang Zhang, Yile Huang, Feng Yang, Liangqiang He, Yuying Li, Yi Ching Esther Wan, Yingzhe Ding, Kui Ming Chan, Ting Xie, Hao Sun, Huating Wang
Luca Pinton, Moustafa Khedr, Valentina M. Lionello, Shilpita Sarcar, Sara M. Maffioletti, Sumitava Dastidar, Elisa Negroni, Sungwoo Choi, Noreen Khokhar, Anne Bigot, John R. Counsell, Andreia Sofia Bernardo, Peter S. Zammit, Francesco Saverio Tedesco
Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier. This combined stem cell and gene therapy can potentially protect diseased motor neurons in the spinal cord of patients with amyotrophic lateral sclerosis, a fatal neurological disorder known as ALS or Lou Gehrig's disease.
Fei Yang, Jingtao Pang, Guolong Liu, Yang Yang, Shenguang Qin, Ying Zhang, Yongrong Lai, Dan Liang, Yuxuan Wu
Zaoqu Liu, Siyuan Weng, Qin Dang, Hui Xu, Yuqing Ren, Chunguang Guo, Zhe Xing, Zhenqiang Sun, Xinwei Han
Jodie Hay, Anuradha Tarafdar, Ailsa Holroyd, Hothri A Moka, Karen M Dunn, Alzahra Alshayeb, Bryony H Lloyd, Jennifer Cassels, Natasha Malik, Ashfia F Khan, IengFong Sou, Jamie Lees, Hassan Nb Almuhanna, Nagesh Kalakonda,
Mathieu Amand, Philipp Adams, Rafaela Schober, Gilles Iserentant, Jean-Yves Servais, Michel Moutschen, Carole Seguin-Devaux
Yuki Sato, Mugiho Shigematsu, Maria Shibata-Kanno, Sho Maejima, Chie Tamura, Hirotaka Sakamoto
Andrew J. Stout, Miriam L. Rittenberg, Michelle Shub, Michael K. Saad, Addison B. Mirliani, David L. Kaplan
James W McNamara, Ben L Parker, Holly K Voges, Neda Rahmani R Mehdiabadi, Francesca Bolk, Dylan D Chung, Natalie Charitakis, Jeff Molendijk, Sean Lal, Mirana Ramialison, Kathy Karavendzas, Hayley L Pointer, Petros Syrris, Luis R Lope
Marko Marjanovic, Ana-Matea Mikecin Drazic, Marija Mioc, Filip Klicek, Mislav Novokmet, Gordan Lauc, Marijeta Kralj
Xiaofei Li, Zaneta Andrusivova, Paulo Czarnewski, Christoffer Mattsson Langseth, Alma Andersson, Yang Liu, Daniel Gyllborg, Emelie Braun, Ludvig Larsson, Lijuan Hu, Zhanna Alekseenko, Hower Lee, Christophe Avenel, Helena Kopp Kallner
Yiming Chao, Yang Xiang, Jiashun Xiao, Shihui Zhang, Weizhong Zheng, Xiaomeng Wan, Zhuoxuan Li, Mingze Gao, Gefei Wang, Zhilin Chen, Mo Ebrahimkhani, Can Yang, Angela Ruohao Wu, Pentao Liu,
Arshad Ahmed Padhiar, Xiaohong Yang, Zhu Li, Jinqi Liao, İlyas Ali, Wei Shu, Arif Ali Chishti, Liangge He, Gulzar Alam, Abdullah Faqeer, Yan Zhou, Shuai Zhang, Ting Wang, Tao Liu,
Mitochondria are remarkable shape-shifting organelles that have long been understood as the powerhouses inside our cells.
Naoki Takahashi, Nobuo Ogita, Toshiya Koike, Kohei Nishimura, Soichi Inagaki, Masaaki Umeda
Hung-Chang Chen, Nico Mueller, Katherine Stott, Eilidh Rivers, Chrysa Kapeni, Carolin M Sauer, Flavio Beke, Stephen Walsh, Nicola Ashman, Louise M O'Brien, Amir Rafati Fard, Arman Godsinia, Fadwa Joud, Olivier Giger,
Haiyan Hu, Xiangrong Song, Lin Zhao, Lanyue Hu, Chu Xu, Yanjuan Lin, Manying Zhou, Xiaolan Lian, Lina Zhang
Travis J Cherelli, Nicole Grieshaber, Cody Appa, Scott S Grieshaber
Anthony M Kyriakopoulos, Peter A Mccullough, Greg Nigh, Stephanie Seneff
Stephanie M Kronstadt, Divya B Patel, Louis J Born, Daniel Levy, Max J Lerman, Bhushan Mahadik, Shannon T McLoughlin, Arafat Fasuyi, Lauren Fowlkes, Lauren Hoorens van Heyningen, Amaya Aranda, Sanaz Nourmohammadi Abadchi, Kai-Hua Chang,
Hui Qi, Enpu Shen, Beibei Li, Zhiwen Wu, Yongsheng Jie, Rui Zheng, Xiong Shu, Lei Chen, Danping Liu, Cheng'ai Wu
Jiahn Choi, Michele Houston, Ruixuan Wang, Kenny Ye, Wenge Li, Xusheng Zhang, Derek M Huffman, Leonard H Augenlicht
Juliet Shen, Chai Foong Lai, Anamaria Balic, Pierfrancesco Pagella, Martin E. Schwab, Thimios Mitsiadis
Peixiang Zhang, Joseph J Munier, Laurent Vergnes, Carrie B Wiese, Jenny C Link, Fahim Abbasi, Emilio Ronquillo, Antonio Munoz, Yu-Lin Kuang, Meng Liu, Gabriela Sanchez, Akinyemi Oni-Orisan, Carlos Iribarren, Michael J. McPhaul,
Scott Atwell, Dominik J. E. Waibel, Sayedali Shetab Boushehri, Carsten Marr, Matthias Meier
A trio of studies in this issue of Cell Stem Cell catalogs the anatomical and functional relationship of intestinal lymphatics with epithelial stem cells, defining an important niche role for the lymphatic endothelium.
The Act on the Safety of Regenerative Medicine regulates cell-based interventions in Japan. Recent revisions to the law require disclosure of explanatory and consent materials for interventions seeking approval. In this Forum, we present an updated a
Xie and colleagues propose a regulatory mechanism of hepatic bile acid metabolism in colitis pathogenesis. They find that the hepatic CYP8B1-cholic acid metabolic axis impairs Lgr5+ intestinal stem cell renewal by repressing PPARα, thus exacerbating
Fu and colleagues profiled a stem cell-derived microfluidic amniotic sac embryoid (μPASE) using single-cell RNA sequencing. Molecular maps of lineage diversifications from the pluripotent human epiblast toward the amniotic ectoderm, primitive streak
We describe hPSC-derived models of FHF, aSHF, and pSHF development spanning the mesoderm, progenitor, and cardiomyocyte stages. Comparison between the hPSC-derived and the corresponding mouse populations revealed conserved developmental trajectories
In this issue of Cell Stem Cell, Pham et al. report that naive human pluripotent stem cells can be differentiated into extraembryonic mesoderm cells (EXMCs). EXMCs are maintained for up to 70 days, resemble human and monkey extraembryonic mesoderm,
Muscle stem cells (MuSCs) exhibit different metabolic profiles depending on their activity, however the mechanisms by which mitochondria affect MuSC fate has been understudied. In this issue of Cell Stem Cell, Hong et al. (2022) and Baker et al. (2
In this issue of Cell Stem Cell, Yang et al. devise a protocol for induction and differentiation of human heart-field precursors, drawing on inspiration from in vivo development. Intricate computational analyses uncovered conserved factors governin
The latest research on plants brought to you by Newswise.
Jari Koistinaho, Marja Koskuvi, Elina Pörsti, Ying Chieh Wu, Kalevi Trontti, Amanda McQuade, Ilkka Ojansuu, Tyrone Cannon, Jouko Lönnqvist, Sebastian Therman, Jaana Suvisaari, Jaakko Kaprio, Mathew Blurton-Jones, Iiris Hovatta,
Anna Shirazyan, Haeyoung Park, Ariell M Joiner, Justine Ra, Melissa S Kim, Archana Kumari, Nicole E Franks, Tien Peng, Robert M Bradley, Charlotte M Mistretta, Andrzej A Dlugosz, Benjamin L Allen
Lin-Yi Zhang, Yi-Ying Xiong, Ming-Yan Liao, Xiao Qing, Xiao-Qiong Tang, Luo Xiao-Hua, Hong-Bin Zhang, Wang Li, Liu Lin
Zhenwei Zhu, Jingyu Li, Jingxian Liu, Yuan He, Yan Xue, Xiangchan Hong, Zeying Jiang, Dangu Luo, Pei Guo, Kaitai Yao, Lin Chen
Beatriz Parejo-Alonso, Alba Royo-Garcia, Pilar Espiau-Romera, Sarah Courtois, Alvaro Curiel-Garcia, Sladjana Zagorac, Isabel Villaoslada, Kenneth P. Olive, Christopher Heeschen, Patricia Sancho