Immunotherapy of multi-drug resistant hematologic malignancies with IL-2-activated intentionally mismatched lymphocytes
PreprintsShimon Slavin
Shimon Slavin
Maria Castaneda, Liandra Rodriguez, Jihyun Oh, Hanna Suh, Jiyong Lee
Mehmet Ali Karaca, Derya Dilek Kancagi, Ugur Ozbek, Ercument Ovali, Ozgul Gok
Menghai Zhu, Chong Lian, Gang Chen, Peng Zou, Beng Gang Qin
Yara Hussein, Utkarsh Tripathi, Ashwani Choudhary, Ritu Nayak, David Peles, Idan Rosh, Jose Djamus, Ronen Spiegel, Tali Garin-Shkolnik, Shani Stern
Oier Pastor-Alonso, Irene Dura, Sara Bernardo-Castro, Emilio Varea, Teresa Muro-Garcia, Soraya Martin-Suarez, Juan Manuel Encinas-Perez, Jose Ramon Pineda
Researchers at Cornell University have come up with a reliable, skin-tight computing system that’s easy to attach and detach, and can be used for a variety of purposes – from health monitoring to fashion.
You can't expect a pharmaceutical scientist to switch labs to the facilities available in a television studio and expect the same research output.
Glioblastomas are lethal malignancies that possess a rapidly evolving microenvironment containing necrotic/hypoxic areas, aberrant microvasculature, and glioblastoma stem cells (GSCs) that promote tumor growth, recurrence, and treatment resistance. C
The reciprocal regulation between mesenchymal stem/stromal cells(MSCs)and immune responses is complex and critical for designing cell therapies. Wang et al. discuss the characteristics and functions of MSCs under different pathophysiological cond
Zheng et al. provide a transcriptomic landscape of hematopoietic stem and progenitor cells and microenvironment in human fetal bone marrow and spleen. They uncover the precise timepoint at which hematopoietic stem cells (HSCs) seed fetal bone marrow
Su et al. performed single-nucleus RNA-sequencing analysis to map diversity, molecular properties, disease relevance, and age-dependent dynamics of glial subpopulations in the human hippocampus across the postnatal lifespan. The resulting glial refe
Collecting ducts in the kidney control the balance of water and electrolytes, as well as pH of the urine to maintain body homeostasis. Shi et al.1 recently reported in Nature Biotechnology a protocol to generate functional collecting duct cells from
A recent study1 demonstrates how hematopoietic stem cells (HSCs) contribute minimally to blood and immune cell production during development and only become active postnatally. The work also reveals how Mecom expression can be used to distinguish rar
Vikas Nanda has spent more than two decades studying the intricacies of proteins, the highly complex substances present in all living organisms.
Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumours in 3D models. The University of Bristol-led advance, published in Biofabrication, would allow clinicians to treat the models, known as spheroids, with chemotherapy drugs and radiation to help them understand an individual patient’s resistance to therapies.
Valeria Scagliotti, Maria Lillina Vignola, Thea L Willis, Mark Howard, Eugenia Marinelli, Carles Gaston-Massuet, Cynthia Lilian Andoniadou, Marika Charalambous
Anita E M Kneppers, Marine Theret, Sabrina Ben Larbi, Linda Gsaier, Audrey Saugues, Carole Dabadie, Arnaud Ferry, Kei Sakamoto, Rémi Mounier
Leading culture collection networks in the EU and the U.S. announced today the signing of a Memorandum of Understanding to enhance their cooperation to promote microbial resources and innovation in biotechnology.
Canadian chemists specializing in nanotechnology draw inspiration from nature to create molecular transporters that optimize the release of therapeutic drugs.
Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.
Microalgae play an important role in the Earth’s climate, converting carbon dioxide into solid carbon. This research sought new ways to study these microalgae and their associated bacterial communities across time and space. The researchers created a new co-culture method called a “porous microplate” that passes nutrients and molecules associated with metabolism between culture cells while blocking physical contact between algae in adjacent wells.
A new gene editing technique developed by University of Oregon researchers compresses what previously would have been years of work into just a few days, making new kinds of research possible in animal models.
Qianqi Zhu, Miaoying Tan, Chengniu Wang, Yufei Chen, Chenfei Wang, Junqi Zhang, Yijun Gu, Yuqi Guo, Jianpeng Han, Lei Li, Rongrong Jiang, Xudong Fan, Huimin Xie, Liang Wang,
Alexandra Chrysanthou, Minerva Bosch-Fortea, Julien Gautrot
Vaishali Yadav, Papri Das, RamKrishna Mishra, Richa Arya
Pedro Silva Couto, Sam A. Molina, Denis O’Sullivan, Liam O'Neill, Alexander M. Lyness, Qasim Rafiq
Julie Necarsulmer, Jeremy Simon, Baggio Evangelista, YouJun Chen, Xu Tian, Sara Nafees, Ariana Marquez Gonzalez, Ping Wang, Deepa Ajit, Viktoriya Nikolova, Kathryn Harper, Jennifer Ezzell, Adriana Beltran, Sheryl Moy,
Shahan Mamoor
Shahan Mamoor
Shahan Mamoor
Shahan Mamoor
Shahan Mamoor
Shahan Mamoor
Yuka Sakata, Keren Cheng, Michinori Mayama, Yasunari Seita, Andrea J Detlefsen, Clementina A Mesaros, Trevor M Penning, Kyosuke Shishikura, Wenli Yang, Richard J Auchus, Jerome F Strauss, Kotaro Sasaki
Shahan Mamoor
Shahan Mamoor
Shahan Mamoor
Shahan Mamoor
Sang Hwa Kim, Kye D Nichols, Eric N Anderson, Yining Liu, Nandini Ramesh, Weiyan Jia, Connor J Kuerbis, Mark Scalf, Lloyd M. Smith, Udai Bhan Pandey, Randal S Tibbetts
Cancer immunotherapies, such as immune checkpoint inhibition therapy, have been attracting attention in recent years as new methods for treating cancer.
Researchers found a much faster way to screen soil bacteria as potential biostimulants and bio-pesticides.
Shahan Mamoor
Shahan Mamoor
Shahan Mamoor
Shahan Mamoor
Shahan Mamoor
Shahan Mamoor
Richard C Chang, Erika M. Joloya, Zhuorui Li, Bassem M Shoucri, Toshi Shioda, Bruce Blumberg