Feature Channels: Pharmaceuticals

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Scientists at Fred Hutchinson Cancer Research Center identified a tiny protein in scorpion venom that rapidly accumulates in joint cartilage. Then they linked these mini-proteins with steroids to reverse inflammation in rats with arthritis. The researchers found that the drugs concentrated in the joints, potentially avoiding the body-wide toxicities and infection risks caused by nontargeted steroid treatment.

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Coriell Life Sciences, a trusted bioinformatics company, was proud to accept the Excellence Award in the Cost Containment category at the Pharmacy Benefit Management Institute’s (PBMI) 25th Annual National Conference in Orlando, FL.

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Value in Health, the official journal of ISPOR—the professional society for health economics and outcomes research, announced today the publication of new research showing that insurer approval rates for PCSK9i prescriptions remain low.

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A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.

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With drug resistance a major challenge in the fight against cancer, a discovery by University of California, Irvine biologists could offer new approaches to overcoming the obstacle. Their research reveals that a mechanism enabling the diseased cells to scavenge dead cell debris for nourishment holds a pivotal role.

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A potential drug target has been identified in a newly mapped protein of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19). The structure was solved by a team including the University of Chicago (U of C), the U.S. Department of Energy’s (DOE) Argonne National Laboratory, Northwestern University Feinberg School of Medicine and the University of California, Riverside School of Medicine (UCR).

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Researchers at Washington University School of Medicine in St. Louis have identified a way to make radiation therapy for colorectal cancer more effective by inhibiting a protein found in cancer cells in the gut.

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The number of treatments for rare diseases affecting children has increased, a new study suggests. But federal incentives intended to encourage drug development for rare conditions are being used more often to expand the use of existing drugs rather than for creating new ones.

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The net cost of prescription drugs – meaning sticker price minus manufacturer discounts – rose over three times faster than the rate of inflation over the course of a decade, according to a study published today in JAMA. It’s the first to report trends in all brand name net drug costs in the U.S.

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The National Comprehensive Cancer Network (NCCN) Oncology Research Program (ORP) today announced three research projects selected to receive funding to improve healthcare provider performance and/or healthcare quality, focusing on enhancing patient care and outcomes for people with NSCLC.

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Doctors face a difficult decision when they must choose a drug combination that will benefit the person sitting before them in an exam room. Statistics can’t show how any one person will respond to a reatment.works in people. Dr. Sarah Adams is using a $1.2M to find better ways to predict which women will benefit from her drug combination, now in clinical trials.

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ISPOR—The Professional Society for Health Economics and Outcomes Research (HEOR) announced a new webinar on its ISPOR 2020 Top 10 HEOR Trends report. The free webinar will be held Thursday, March 26, 2020 at 11:00AM EDT and is available for both members and nonmembers.

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A group of University of Alberta researchers who have discovered why the drug remdesivir is effective in treating the coronaviruses that cause Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS) expect it might also be effective for treating patients infected with the new COVID-19 strain.

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The emergence and rapid increase in cases of coronavirus disease 2019 (COVID-19), a respiratory illness caused by a novel coronavirus, pose complex challenges to the global public health, research and medical communities, write federal scientists from NIH's National Institute of Allergy and Infectious Diseases (NIAID) and from the Centers for Disease Control and Prevention (CDC).

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Chronic pain, a disabling health condition that affects 50 million to 116 million Americans, is often treated with opioids, despite little evidence of long-term benefit and risks of addiction and overdose. Do patients know their options beyond opioids? Are doctors telling them?

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An announcement that the Harrington Discovery Institute at University Hospitals is accepting letters of intent for the 2021 Harrington Scholar-Innovator Award. The award offers inventive physician-scientists resources and expertise to advance their discoveries into medicines.