Daytime napping is common among older adults. The longitudinal relationship between daytime napping and cognitive aging, however, is unknown.
Mayo Clinic researchers have identified a new set of molecular markers in blood plasma. This discovery could lead to the development of improved diagnostic tests for Alzheimer's disease. Alzheimer's disease is the most common form of dementia, affecting 6.2 million people in the U.S. The Mayo Clinic study, published in eBioMedicine, is the first study to focus on RNA molecules in plasma as biomarkers for Alzheimer's disease in African Americans — the population at greatest risk for developing Alzheimer's disease. This approach enabled researchers to pinpoint specific molecules in plasma that could serve as biomarkers to confirm a diagnosis of Alzheimer's disease in this population.
The Dementia Care Study (D-CARE), a nation-wide clinical trial assessing the effectiveness of different approaches to caring for people with Alzheimer’s disease and other dementias, has reached its recruitment goal by enrolling 2,176 persons living with dementia and their caregivers
Mayo Clinic researchers say senolytic drugs can boost a key protein in the body that protects older people against aspects of aging and a range of diseases. Their findings, which are published in eBioMedicine demonstrate this in mice and human studies. Senolytics developed at Mayo Clinic and given once clear the bloodstream of senescent or "zombie" cells. These cells contribute to multiple diseases and negative aspects of aging. This study shows that the removal of senescent cells significantly boosts the production of a protective protein called a-klotho.
Cognitive decline is the biggest factor in determining how long patients with Alzheimer’s disease will live after being diagnosed, according to a new study from researchers at UT Southwestern. The findings, published in the Journal of Alzheimer’s Disease, are a first step that could help health care providers provide reliable prediction and planning assistance for patients with Alzheimer’s disease and their families.
People living with neurological or psychiatric conditions may have an increased likelihood of having a second such condition in the future, and their sex influences their risk, according to new research.
The 147th Annual Meeting of the American Neurological Association (taking place in-person October 22–25, 2022 in Chicago) will explore new frontiers in neurology, including climate change and the brain, lab-grown brain structures for studying disease, and addressing disparities in neurologic care.
New Neuroscience Institute to Focus Research on Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease, and will treat patients with other neurological conditions, including epilepsy, seizures and Alzheimer’s Disease
A Johns Hopkins Medicine study of about 50 people with Alzheimer’s disease has added to evidence that damage to the inner ear system that controls balance is a major factor in patients’ well-documented higher risk of falling.
The University of Kentucky’s Sanders-Brown Center on Aging has been around for nearly half a century. In that time, they have built an international reputation for best-in-class research into a disease that kills more people every year than breast and prostate cancer combined – Alzheimer’s disease. There are several components to the ongoing research at Sanders-Brown, one is exploring ways to detect Alzheimer’s earlier in a person’s life.
Researchers have received grants from the Florida Department of Health’s Ed and Ethel Moore Foundation for Alzheimer’s Disease Research, for programs focused on the mechanism of genes involved in neurodegeneration using novel genetic models, and to develop a culturally relevant model to diagnose and manage dementia in rural underserved communities.
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As scientists around the world seek for solutions for Alzheimer’s disease, a new study reveals that two indigenous groups in the Bolivian Amazon have among the lowest rates of dementia in the world.
Researchers have discovered two types of brain cells that play a key role in dividing continuous human experience into distinct segments that can be recalled later. The discovery provides new promise as a path toward development of novel treatments for memory disorders such as dementia and Alzheimer’s disease.
People who are more physically fit are less likely to develop Alzheimer’s disease than people who are less physically fit, according to a preliminary study released today, February 27, 2022, that will be presented at the American Academy of Neurology’s 74th Annual Meeting being held in person in Seattle, April 2 to 7, 2022 and virtually, April 24 to 26, 2022.
Now that the holiday season has concluded, perhaps you’ve noticed the warning signs of Alzheimer’s disease or related dementia in aging family members. George Grossberg, M.D., the Samuel W. Fordyce professor and director of geriatric psychiatry at Saint Louis University School of Medicine, said it is during family gatherings that caregivers often notice older adults 65 and over may be slipping cognitively.
Among people with no memory or thinking problems, having a poor score on a simple memory test may be linked to biomarkers in the brain associated with Alzheimer’s disease as well as very early signs of memory impairment that precede dementia by several years, according to a study published in the February 23, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.
To help neurologists, patients and their families understand the current evidence on the use of aducanumab to treat Alzheimer’s disease, the American Academy of Neurology (AAN) has issued an evidence-in-focus article, published in the February 23, 2022, online issue of Neurology®, the medical journal of the AAN. The article also includes a discussion of the safety, costs, administration, and quality-of-life issues related to aducanumab to provide people with a more detailed understanding of the new treatment.
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