Feature Channels: Biotech

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Released: 4-Nov-2022 12:00 PM EDT
Cell-attribute aware community detection improves differential abundance testing from single-cell RNA-Seq data
 Preprints

Alok Maity, Andrew Teschendorff

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Released: 4-Nov-2022 12:00 PM EDT
Integrated analysis of ovarian cancer stem cells-associated lncRNA-miRNA-mRNA network via microarray and Gene Expression Omnibus database
 Preprints

Zheng Li, Ying Li, Jinling Bai, Zhijiao Wang, Yingying Zhou

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Released: 4-Nov-2022 12:00 PM EDT
Assessment of the potential of cold plasma-pretreated beta-tricalcium phosphate in combination with periodontal ligament stem cells to enhance bone regeneration in vivo
 Preprints

M Miletić, N Puač, N Škoro, B Brković, M Andrić, Bb Prokić, V Danilović, S Milutinović-Smiljanić, O Mitrović-Ajtić, S Mojsilović

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Released: 4-Nov-2022 12:00 PM EDT
Evaluating the efficacy of human dental pulp stem cells and scaffold combination for bone regeneration in animal models: A systematic review and meta-analysis
 Preprints

Amin Namjoynik, Asiful Islam, Mohammad Islam

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Released: 4-Nov-2022 12:00 PM EDT
Glycolytic metabolism and differentiation remodeling of hematopoietic stem cells in lung cancer
 Preprints

Ziqi Guo, Shiming Pu, Liu Yang, Yaping Liu, Xin Li, Hongxia Zhao, Zuping Zhou, Cheng Yang

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Newswise: New Startup Develops Potential Cure for Type 1 Diabetes
Released: 3-Nov-2022 5:20 PM EDT
New Startup Develops Potential Cure for Type 1 Diabetes
 Georgia Institute of Technology

Insulin injections to treat Type 1 diabetes could become a thing of the past, but finding the cure faces many challenges. Although transplanting insulin-producing cells represents a promising approach, this cell therapy requires immunosuppression to prevent rejection. Georgia Tech researchers have developed a new biomaterial called iTOL-100 that could cure Type 1 diabetes by inducing immune acceptance of curative transplanted cells without immunosuppression.

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Released: 3-Nov-2022 12:00 PM EDT
HB-EGF and zinc activate EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures
 Preprints

Oier Pastor-Alonso, Irene Dura, Sara Bernardo-Castro, Emilio Varea, Teresa Muro-Garcia, Soraya Martin-Suarez, Juan Manuel Encinas-Perez, Jose Ramon Pineda

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Released: 3-Nov-2022 12:00 PM EDT
Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-causing mutations
 Preprints

Yara Hussein, Utkarsh Tripathi, Ashwani Choudhary, Ritu Nayak, David Peles, Idan Rosh, Jose Djamus, Ronen Spiegel, Tali Garin-Shkolnik, Shani Stern

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Released: 3-Nov-2022 12:00 PM EDT
N6-methyladenosine-mediated changes in SOCS3 expression regulate skeletal muscle stem cell senescence
 Preprints

Menghai Zhu, Chong Lian, Gang Chen, Peng Zou, Beng Gang Qin

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Released: 3-Nov-2022 12:00 PM EDT
Preparation of Cell-Loaded Microbeads as Stable and Injectable Delivery Platforms for Tissue Engineering
 Preprints

Mehmet Ali Karaca, Derya Dilek Kancagi, Ugur Ozbek, Ercument Ovali, Ozgul Gok

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Released: 3-Nov-2022 12:00 PM EDT
A FOXC2 inhibitor, MC-1-F2, as a therapeutic candidate for targeting EMT in castration-resistant prostate cancer
 Preprints

Maria Castaneda, Liandra Rodriguez, Jihyun Oh, Hanna Suh, Jiyong Lee

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Released: 3-Nov-2022 12:00 PM EDT
Immunotherapy of multi-drug resistant hematologic malignancies with IL-2-activated intentionally mismatched lymphocytes
 Preprints

Shimon Slavin

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Released: 3-Nov-2022 12:00 PM EDT
Gene expression profiles in mesenchymal stromal cells from bone marrow, adipose tissue and lung tissue of COPD patients and controls
 Preprints

Dennis Kruk, Anna Yeung, Alen Faiz, Nick H.T. Ten Hacken, Wim Timens, Toin H. Kuppevelt, Willeke Daamen, Danique Hof, Martin C. Harmsen, Mauricio Rojas, Irene H. Heijink

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Released: 3-Nov-2022 12:00 PM EDT
Oxygen-sensitive TERT Promoter Methylation Regulates Telomerase Activity
 Preprints

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Released: 3-Nov-2022 11:05 AM EDT
New ‘smart tattoos’ tackle tech challenges of on-skin computing
 Cornell University

Researchers at Cornell University have come up with a reliable, skin-tight computing system that’s easy to attach and detach, and can be used for a variety of purposes – from health monitoring to fashion.
Newswise: Artificial Intelligence Makes Enzyme Engineering Easy
Released: 3-Nov-2022 10:25 AM EDT
Artificial Intelligence Makes Enzyme Engineering Easy
 Osaka University

You can't expect a pharmaceutical scientist to switch labs to the facilities available in a television studio and expect the same research output.

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Released: 3-Nov-2022 5:00 AM EDT
Glioblastoma Stem Cell HISTArionics
 Cell Stem Cell

Glioblastomas are lethal malignancies that possess a rapidly evolving microenvironment containing necrotic/hypoxic areas, aberrant microvasculature, and glioblastoma stem cells (GSCs) that promote tumor growth, recurrence, and treatment resistance. C

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Released: 3-Nov-2022 5:00 AM EDT
Reciprocal Regulation of Mesenchymal Stem Cells and Immune Responses
 Cell Stem Cell

The reciprocal regulation between mesenchymal stem/stromal cells（MSCs）and immune responses is complex and critical for designing cell therapies. Wang et al. discuss the characteristics and functions of MSCs under different pathophysiological cond

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Released: 3-Nov-2022 5:00 AM EDT
Uncovering the Emergence of HSCs in the Human Fetal Bone Marrow by Single-Cell RNA-Seq Analysis
 Cell Stem Cell

Zheng et al. provide a transcriptomic landscape of hematopoietic stem and progenitor cells and microenvironment in human fetal bone marrow and spleen. They uncover the precise timepoint at which hematopoietic stem cells (HSCs) seed fetal bone marrow

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Released: 3-Nov-2022 5:00 AM EDT
A Single-Cell Transcriptome Atlas of Glial Diversity in the Human Hippocampus Across the Postnatal Lifespan
 Cell Stem Cell

Su et al. performed single-nucleus RNA-sequencing analysis to map diversity, molecular properties, disease relevance, and age-dependent dynamics of glial subpopulations in the human hippocampus across the postnatal lifespan. The resulting glial refe

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