Liver fibrosis linked to reduced cognitive ability, brain volume
Yale School of Medicine
Collaborative work by teams at the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University (UPF), University of California, Irvine (UCI), and the Institute for Research in Biomedicine (IRB Barcelona) has shown that interplay between circadian clocks in liver and skeletal muscle controls glucose metabolism.
Researchers with UC San Diego School of Medicine identified a potential new drug that improved liver fibrosis in patients with NASH by 27%.
A genetic marker discovered by UT Southwestern Medical Center researchers could help physicians predict which patients with hepatocellular carcinoma are most likely to develop resistance to the drug lenvatinib. The finding, published in the journal Gastroenterology, may lead to alternative treatments for the most common form of liver cancer.
Los investigadores de Mayo Clinic identificaron un amplio rango de sustancias químicas ambientales en la bilis humana de pacientes con colangitis esclerosante primaria, una enfermedad hepática crónica y poco común que afecta los conductos biliares. El estudio, que se publicó en Exposome, representa una nueva frontera de investigación en el Centro de Medicina Personalizada en Mayo Clinic que explora el exposoma, la medida en que el ambiente contribuye a las enfermedades y la salud.
Pesquisadores da Mayo Clinic identificaram uma ampla variedade de substâncias químicas presentes no ambiente na bile humana em pacientes com colangite esclerosante primária, uma doença hepática crônica rara nos dutos biliares. O estudo, publicado na revista Exposome, representa uma nova frente de pesquisa do Centro de Medicina Individualizada da Mayo Clinic que estuda o expossoma (a medida dos fatores ambientais que contribuem para a saúde e o aparecimento de doenças).
مدينة روتشستر، ولاية مينيسوتا — استطاع الباحثون في مايو كلينك تحديد عدد من الكيماويات البيئية في العصارة الصفاروية للمرضى المصابين بالْتِهابُ الأَقْنِيَةِ الصَّفْراوِيَّةِ المُصَلِّب الأوَّلي وهو مرض كبدي مزمن نادر يصيب القنوات الصفراوية. يمثل البحث المنشور حول الإكسبوزوم فتحًا جديدًا في مجال البحث العلمي، أنجزه مركز مايو كلينك للطب الفردي. يحاول هذا البحث فهم خبايا الإكسبوزوم، وهو قياس مدى تأثير العوامل البيئية على الصحة والإصابة بالأمراض.
Dozens of children die each year in the U.S. while waiting for a new liver. A new analysis suggests that greater use of partial liver transplants — either from a living donor or by splitting a deceased donor’s liver for two recipients — could save many of these young lives.
Mayo Clinic researchers have identified a diverse range of environmental chemicals in human bile in patients with primary sclerosing cholangitis, a rare, chronic liver disease of the bile ducts. The study, published in Exposome, represents a new frontier of research at Mayo Clinic's Center for Individualized Medicine that explores the exposome, the measure of environmental contributors to disease and health.
The percent of metabolic associated fatty liver disease (MAFLD), the leading global cause of liver disease, is increasing in U.S. adults, according to a study presented Friday at ENDO 2023, the Endocrine Society’s annual meeting in Chicago, Ill.
Researchers at the Icahn School of Medicine at Mount Sinai have uncovered a trio of immune cells within tumor niches that are associated with immunotherapy response in hepatocellular carcinoma (HCC). HCC is the primary type of liver cancer and one of the most deadly cancers worldwide.
Physicians at Cedars-Sinai Cancer are using a unique chemotherapy delivery system that offers hope to colorectal cancer patients whose disease has spread and who now have inoperable liver tumors. Cedars-Sinai is one of the few centers in the area to offer the therapy, called hepatic artery infusion (HAI) pump chemotherapy.
Rohit Loomba, MD, has been named chief of the Division of Gastroenterology and Hepatology at University of California San Diego School of Medicine. His new role is effective June 1, 2023.
As more families consider bariatric surgery a viable option to treat their child’s obesity, it is important to stay up-to-date on the latest research on weight loss. You can find the latest research on bariatric surgery and other weight loss options in the Weight Loss channel on Newswise, where journalists can find story ideas on this trending topic.
The research group of Professor Kamimura in Niigata University have applied the novel, liver lobe-specific hydrodynamic delivery procedure to primates (baboons) for the first time.
Colorectal cancer is on the rise among younger adults. According to the American Cancer Society, the proportion of cases among people under 55 increased from 11% in 1995 to 20% in 2019, and it is now the leading cause of cancer-related deaths for men younger than 50.
The June issue of The American Journal of Gastroenterology includes a new joint society guideline on pharmacological management of chronic idiopathic constipation and consumption of kiwifruit to relieve constipation.
A tiny population of T-cells could serve as a much-needed biomarker—and a potential therapeutic target—for pediatric acute liver failure, according to new research from Children’s Hospital Los Angeles.
A roundup of the latest medical discoveries and faculty news at Cedars-Sinai in May 2023.