The $50,000 MacLean Center Prize in Clinical Ethics and Health Outcomes, the largest in clinical medical ethics, was awarded this year to Emory University's William Foege, MD, MPH.
In a new study published in Nature, scientists from the University of Chicago show how a common RNA modification plays an important role in the process of learning and memory formation.
ACCSIS-Chicago—led by University of Chicago cancer specialists Karen Kim, MD, MS, and Blase Polite, MD, MPP—has been awarded nearly $6 million over five years to test novel ways to improve CRC screening and follow-up among groups that have not been screened.
New research by scientists from the University of Chicago shows that just one gene controls whether a certain species of butterfly has white or yellow spots on its wings.
Nearly 120 million prescriptions for a thyroid medicine called levothyroxine are filled each year, but many patients with hypothyroidism never get the benefit. A new study pinpoints a consistent inherited mutation that prevents the only current treatment from doing its job.
A new study comparing DNA and RNA data from Nigerian breast cancer patients to patients in a United States database found that aggressive molecular features were far more prevalent in tumors from women of African ancestry than women of European ancestry. Those differences could explain disparities in breast cancer mortality for black women across the African Diaspora and hasten a shift to precisely targeted therapies.
A team of researchers at the University of Chicago has received a $3.4 million grant from the National Institutes of Health. The funding will help the team develop robotic arms patients can control with their minds that receive sensory feedback from attached prosthetic hands.
Researchers have identified an independent prognostic factor, cancer/testis antigen 45, that is associated with extended disease-free survival for women with advanced ovarian cancer. Patients with high levels of CT45 in their tumors lived more than seven times as long as patients who lacked sufficient CT45.
A study in Nature Biomedical Engineering shows that skin stem cells, modified via CRISPR and transplanted back to donor mice, can protect addicted mice from cocaine-seeking and overdose.
Getting magnetic resonance imaging (MRI) scans twice a year instead of one annual mammogram is far more effective at detecting early breast cancers in young women with a high-risk genetic profile than mammograms alone, according to a research team based at the University of Chicago Medicine and the University of Washington, Seattle.
The majority of partnered, home-dwelling people in the U.S. with dementia are sexually active, according to a University of Chicago Medicine study out this week in the Journal of the American Geriatrics Society.
The University of Chicago Medicine and Almoosa Specialist Hospital, a private hospital in the Al-Ahsa region of Saudi Arabia offering comprehensive medical care, have signed a collaboration agreement.
Ovarian cancer cells that interact with cancer-associated fibroblasts can mobilize glycogen as an energy source, leading to proliferation, invasion and metastasis. Blocking glycogen mobilization in cancer cells might reduce tumor spread.
Interactions between radiation therapy and the immune system can improve cancer treatment. The cellular carnage caused by radiation attracts scavengers, such as dendritic cells, that present cancer cell fragments to T cells. This study suggests novel ways to improve treatment by using radiation to boost immunotherapy.
According to a new study, about one in five children regularly use prescription medications, and nearly one in 12 of those children are at risk for experiencing a harmful drug- drug interaction.
The University of Chicago Medicine and Humana Inc. have entered into a value-based agreement designed to offer a coordinated, patient-centered experience to help Humana Medicare Advantage members achieve their best health.
A study that enrolled more than 2,000 Nigerian women found that disparities in breast cancer mortality disproportionately impact women of African ancestry. Nigerian women with mutations in breast cancer genes have higher risks than women in the U.S. with mutations in the same genes. Inherited breast cancer plays a bigger role in Nigeria.
A new point-of-care test for the parasite Toxoplasma gondii can be performed with a drop of the mother’s blood. The test meets the WHO’s criteria. It is sensitive, specific, quick, easy to perform, and inexpensive.
LIF6, a dead gene that came back to life, prevents cancer by killing cells with DNA damage.
As part of a project titled Engaging Muslim Activists for Research on Community Health (E-MARCH) -- led by Aasim Padela, MD, associate professor of medicine and Director of Initiative on Islam and Medicine at the University of Chicago -- UMMA Clinic of Los Angeles, California, hosted fourteen Muslim community leaders to discuss Muslim health disparities and community-based health research.
Prescriptions for diabetes medications increased in the first two years after states expanded eligibility for Medicaid as part of the Affordable Care Act, compared to states that didn’t expand Medicaid, according to a new analysis by researchers from UChicago and USC.
The University of Chicago Medicine has received another three-year accreditation from the Commission on Cancer, a voluntary program administered by the American College of Surgeons.
Chicago’s only hospital-based medical flight program began flying a more advanced helicopter this month, an Airbus EC145.
Designation from the National Cancer Institute denotes the highest level of scientific excellence.
The University of Chicago Medicine and the WNBA Chicago Sky officially broke the Guinness World Record for the largest basketball lesson, which took place during this year’s inaugural #ChicagoFit Health and Fitness Festival.
A drug used to treat altitude sickness may help patients with glioblastoma, according to a study published July 4, 2018, in the journal Science Translational Medicine.
More than one-third of women who go to a Catholic hospital for reproductive care aren’t aware they’re seeking obstetrical and gynecological care at a facility that may have limited health care options due to its religious affiliation.
The University of Chicago Medicine has awarded seven capacity-building grants to support community-based violence prevention, intervention, and recovery efforts on Chicago's South Side.
The American Society of Clinical Oncology has chosen Ralph Weichselbaum, Chair of Radiation and Cellular Oncology, Co-Director of the Ludwig Center for Metastasis Research at Univ. of Chicago, to receive the 2018 Karnofsky Award and present the Karnofsky Lecture, a high point of the meeting, on Sat., June 2.
UChicago Medicine cared for 274 adult trauma patients during its first four weeks as a Level 1 trauma center, an average of more than nine patients a day.
The controversial Severe Sepsis and Septic Shock Early Management Bundle study adds weight to the belief that early lactate measurements can make a big difference. This follow-up study found a two percent increase in mortality for each hour of delay in patients with an abnormal lactate value.
Patients who need frequent hospitalization account for a disproportionate amount of health care spending. In 2012, the University of Chicago Medicine began enrolling patients in a clinical trial designed to reduce frequent stays. Hospitalization rates for these patients were 15 to 22 percent lower. They also reported a better experience.
A new study by researchers from the University of Chicago Medicine shows that bacterial signals are crucial to the development of a precursor condition to leukemia, which can be induced by disrupting the intestinal barrier or by introducing a bacterial infection.
The University of Chicago Medicine has signed on to be among seven leading hospitals in the United States to provide specialized medical treatment to patients from the United Arab Emirates.
Using molecular determinants combined with clinical data, UChicago physicians confirm their oligometastasis hypothesis in colorectal cancers with limited spread of disease to the liver.
A letter in the May 3, 2018, NEJM updates reports on the risks of exposure during pregnancy to a supplement, diethylstilbestrol (DES), that is linked to a rare cancer. DES-exposed patients with clear-cell adenocarcinoma had “increased mortality across their life span.”
The University of Chicago Medicine received the prestigious Magnet Recognition Program designation from the American Nurses Credentialing Center for excellence in nursing and patient care.
The University of Chicago Medicine earned its 13th consecutive “A” in hospital safety from The Leapfrog Group.
A protein that plays an important role in embryonic development and nervous system wiring in humans appears to have been borrowed from bacteria. In a new study, scientists from the UChicago and Stanford describe the three-dimensional structure of proteins called teneurins for the first time.
A new study by researchers from the University of Chicago Medicine, based on a 6-month clinical trial, finds that use of a CGM is cost-effective for adult patients with type 1 diabetes when compared to daily use of test strips.
A new study—one of a few to concentrate on microbes in the upper gastrointestinal tract—shows how the typical calorie-dense western diet can induce expansion of microbes that promote the digestion and absorption of high-fat foods. Over time, the steady presence of these microbes can lead to over-nutrition and obesity.
Researchers at the University of Chicago have developed a genetic screening tool that identified two key factors that allow the influenza virus to infect human lung cells. The technique uses new gene editing tools to create a library of modified cells, each missing a different gene, allowing scientists to see which changes impact their response to flu. This in turn could identify potential targets for antiviral drugs.
The Illinois Department of Public Health has approved the University of Chicago Medicine to be a Level 1 adult trauma center, clearing the final regulatory hurdle for the academic health system to launch the critical service on May 1.
In the April 5, 2018 issue of the journal Cell, researchers push for greater emphasis on the neglected viral-surface influenza protein neuraminidase. For decades, flu vaccines have concentrated on hemagglutinin. The authors maintain that a focus on neuraminidase could lower infection rates and lessen severity.
American clinicians rated white patients as significantly more likely to improve and more likely to adhere to recommended treatments than black patients, and to be more personally responsible for their health than black patients.
By taking a high-cost drug with a low-fat meal—instead of on an empty stomach, as prescribed—prostate cancer patients could decrease their daily dose, prevent digestive issues and cut costs by 75 percent.
University of Chicago researchers have begun to unravel the role of RNA epigenetics and chromatin structure in regulation of 5-azacytidine (5-AZA), a well-known DNA hypomethylating agent in MDS and AML. The finding may lead to novel strategies, as well as guidance from clinical biomarkers.
UChicago's Biological Sciences Division moved up one notch to No. 13 — with the paleontology program retaining its top rating and the ecology & evolution program placing 8th — in U.S. News & World Report's survey of the best biological sciences doctoral programs. Meanwhile, the Pritzker School of Medicine placed No. 18 among top medical schools for research.
Fish, mice and likely all modern-day vertebrates share genetic elements first used to develop the unpaired dorsal fin in ancient fish. They later copied these elements to produce paired appendages, like pelvic and pectoral fins, arms and legs.
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