Johns Hopkins Medicine researchers report that a program designed to enhance self-care and lead to more seamless management of chronic obstructive pulmonary disease (COPD) in adults successfully reduced rates of emergency room visits and hospitalization, and the burdensome symptoms and limitations caused by the condition.
For the past 17 years, most scientists around the globe have been using the nucleic acid sequence, or genome, an assembly of DNA information, from primarily a single individual as a kind of “baseline” reference and human species representation for comparing genetic variety among groups of people.
It’s a common scenario in many emergency rooms: A man with a long history of homelessness and schizophrenia reports hallucinations and thoughts of suicide. Should the medical team admit him for hospitalization or treat him with antipsychotic drugs and release him from the ER? Lessons learned from this experience are the focus of the first article in a series of case studies that begins Nov. 15 in the New England Journal of Medicine.
A new study designed to reach hospitalized patients at risk shows that a “real-time” educational conversation, video or leaflet can lower the missed dose rates of drugs that can prevent potentially lethal blood clots in their veins.
Dry Eye Syndrome Slows Reading Rate, Study Suggests 11/15/2018 AddThis Sharing Buttons Share to Facebook Share to TwitterShare to EmailShare to PrintShare to More Slow reading rate and significantly disrupt day to day tasks that require visual concentration for long periods of time . Johns Hopkins researchers report that chronic dry eye, a condition in which natural tears fail to adequately lubricate the eyes, can slow reading rate and significantly disrupt day to day tasks that require visual concentration for long periods of time. Credit: iStock Johns Hopkins researchers report that chronic dry eye, a condition in which natural tears fail to adequately lubricate the eyes, can slow reading rate and significantly disrupt day to day tasks that require visual concentration for long periods of time.
In a new $5.5 million center that spans engineering and cardiology specialties at Johns Hopkins, experts aim to improve the diagnosis and treatment of heart rhythm disorders that affect millions of people by leveraging innovations in cardiac imaging, computer simulations and data science.
Zebrafish eye injected with retinoblastoma tumor cells (green) form a mass in areas close to the injection site. A few of these tumor cells move outside the eye. Credit: Johns Hopkins Medicine By comparing genetic sequences in the eye tumors of children whose cancers spread with tumors that didn’t spread, Johns Hopkins Medicine researchers report new evidence that a domino effect in cells is responsible for the cancer spreading. Their experiments suggest that blocking part of the chain of events — which they successfully accomplished in zebra fish and human cells — stops the growth and spread of the eye tumor cells.
Experimenting with lab-grown brain cancer cells, Johns Hopkins Medicine researchers have added to evidence that a shortage of specific tiny molecules that silence certain genes is linked to the development and growth of pediatric brain tumors known as low-grade gliomas.
The 2018 American Heart Association Scientific Sessions
2018 Cholesterol Guidelines for Heart Health Announced 11/10/2018 AddThis Sharing Buttons Share to Facebook Share to TwitterShare to EmailShare to PrintShare to More . A working group composed of two Johns Hopkins Medicine physicians and their American Heart Association colleagues has released updated clinician guidelines on managing cholesterol as a way to minimize risk for heart attack, stroke and death.
Scientists at Johns Hopkins Medicine say they have identified what may be an ancient light-sensing mechanism in modern mouse retinal cells.
Experimenting with mice, Johns Hopkins Medicine researchers have added to evidence that a hormone best known for helping regulate hunger and body weight might also ease breathing problems experienced during sleep more effectively when given through the nose.
In experiments performed in mice, Johns Hopkins researchers report they have identified the cascade of cell death events leading to the physical and intellectual degeneration associated with Parkinson's disease.
Johns Hopkins Medicine’s “A Woman’s Journey” — Baltimore is an annual women’s health program that features 32 seminars highlighting medical issues that impact women. Topics range from the microbiome to the rise in lung cancer among women who have never smoked to the health benefits of eating chocolate.
A new Johns Hopkins study of more than 75,000 teenagers and children who suffered a firearm-related injury between 2006 and 2014 pinpoints the financial burden of gunshot wounds and highlights the increasing incidence of injury in certain age groups.
The HPV Vaccine: Why Parents Really Choose to Refuse 10/24/2018 AddThis Sharing Buttons Share to FacebookShare to TwitterShare to EmailShare to PrintShare to More Study results suggest safety concerns top the list, and that physicians need to step up their patient education and vaccine recommendations Researchers explain the reasons for why parents chose not to get their child vaccinated with the HPV vaccine Credit: Johns Hopkins Medicine Click the image above to view the video. A new study of survey data finds that only a minority of parents choose not to immunize their children against the sexually transmitted human papillomavirus (HPV) due to concerns that vaccination would encourage or support youth sexual activity, a reason frequently cited by doctors as a barrier to advocating for this vaccine. Instead, the results show, parental concerns that steer young people away from vaccination tend to focus on safety worries, lack of necessity, knowledge about HPV and absence o
The 2018 American College of Rheumatology/American Rheumatology Health Professionals Annual Meeting.
Fighting the Flu: With the Return of Influenza Season, Now is the Best Time to Protect Yourself 10/17/2018 AddThis Sharing Buttons Share to FacebookShare to TwitterShare to EmailShare to PrintShare to More An interview with Lisa Maragakis and Aaron Milstone about the flu. Credit: Johns Hopkins Medicine With the start of the flu season, cases have surfaced in regions around the country, and Johns Hopkins Medicine experts expect to see that number continue to grow through the winter. Doctors recommend that everyone 6 months and older get the flu vaccine each year to prevent the virus or reduce the seriousness if you do get sick.
In a report of the phase II ADvance clinical trial, Johns Hopkins researchers report that people diagnosed under age 65—those with early-onset Alzheimer’s disease—didn’t benefit from deep brain stimulation. Their findings appeared in the July issue of the Journal of Alzheimer’s Disease.
Johns Hopkins students will be presenting posters of their engineering projects designed to fill needs in clinical care
In studies of mouse cells, Johns Hopkins researchers have found that low levels of cellular copper appear to make fat cells fatter by altering how cells process their main metabolic fuels, such as fat and sugar.
Allen Kachalia, M.D., J.D., will become the senior vice president of patient safety and quality for Johns Hopkins Medicine and director of the Armstrong Institute for Patient Safety and Quality, effective Dec. 1.
The National Institutes of Health (NIH) has selected the Johns Hopkins University School of Medicine, Baylor College of Medicine and The University of Texas Health Science Center at Houston to lead one of three “genome centers” for its All of Us Research Program.
Researchers at the Johns Hopkins Kimmel Cancer Center received a $3.1 million grant to study the resistance of limited stage small cell lung cancer to a combination of chemotherapy and radiotherapy (chemoradiation).
The annual American College of Emergency Physicians (ACEP) Scientific Assembly will bring together more than 8,000 emergency medicine physicians, including those from Johns Hopkins Medicine. Johns Hopkins Medicine’s Department of Emergency Medicine faculty will present research findings on a variety of topics.
Fixing or replacing faulty genes has emerged as a key to unlocking cures for numerous devastating diseases. But if the new, engineered genes can’t find their way into the patient’s genomic sequence, they won’t help.
Researchers at Johns Hopkins report that a novel analysis of more than a thousand patients adds to evidence that hospitalization, critical illness and major infection may diminish brain structures that are most commonly affected by Alzheimer’s disease.
In an evaluation of the safety and abuse research on the drug in hallucinogenic mushrooms, Johns Hopkins researchers suggest that if it clears phase III clinical trials, psilocybin should be re-categorized from a schedule I drug—one with no known medical potential—to a schedule IV drug such as prescription sleep aids, but with tighter control.
Driver genes in different metastases from the same patient are remarkably similar, providing optimism for the success of future targeted therapies, according to a published study by Science.
In what Johns Hopkins Medicine researchers call an unusually comprehensive analysis of nationwide data, they conclude that the rate of lawnmower injuries persists at close to 6,400 a year, most of them requiring surgery and hospitalization, and costing an average of $37,000 per patient.
By studying the genome of a kind of octopus not known for its friendliness toward its peers, then testing its behavioral reaction to a popular mood-altering drug called MDMA or “ecstasy,” scientists say they have found preliminary evidence of an evolutionary link between the social behaviors of the sea creature and humans, species separated by 500 million years on the evolutionary tree.
Study at Johns Hopkins Hospital Leads To Changes in Reporting Patient Safety Concerns 09/20/2018 AddThis Sharing Buttons Share to FacebookShare to TwitterShare to EmailShare to PrintShare to More Credit: iStock In a case study published online last week in Academic Medicine, an international team of researchers led by the University of Cambridge and Johns Hopkins Medicine looked at what prevented employees from raising concerns.
$20 million will fund four academic centers to launch the National Career Development Consortium for Excellence in Glycosciences Training
In a new analysis of data submitted to Maryland’s state trauma registry from 2005 to 2017, Johns Hopkins Medicine researchers found that gunshot victims are approximately five times more likely to require blood transfusions, they require 10 times more blood units and are 14 times more likely to die than people seriously injured by motor vehicles, non-gun assaults, falls or stabs.
In a proof of concept study, scientists at Johns Hopkins report they have successfully performed 3D personalized virtual simulations of the heart to accurately identify where cardiac specialists should electrically destroy cardiac tissue to stop potentially fatal irregular and rapid heartbeats in patients with scarring in the heart. The retrospective analysis of 21 patients and prospective study of five patients with ventricular tachycardia, the researchers say, demonstrate that 3D simulation-guided procedures are worthy of expanded clinical trials.
Researchers view cells for hearing in 3D using virtual reality
Immune reactions are usually a good thing--the body's way of eliminating harmful bacteria and other pathogens.
Johns Hopkins Medicine researchers say new experiments using magnetic pulse brain stimulation on people with moderate to severe restless legs syndrome (RLS) have added to evidence that the condition is due to excitability and hyperarousal in the part of the brain's motor cortex responsible for leg movement.
New guidelines released by the U.S. Preventive Services Task Force will give women over 30 years old options about screening for cervical cancer.
Johns Hopkins University School of Medicine leaders plan to invest $100 million over the next five years to hire new faculty and support programs aimed at unraveling the mysteries of biology. Such “basic” science discoveries underpin virtually every major medical breakthrough, say the leaders, and they have appointed structural biologist James Berger, Ph.D., to direct the Johns Hopkins institute dedicated to this effort.
Researchers in the Department of Physical Medicine and Rehabilitation at Johns Hopkins Medicine report that a computerized study of 36 healthy adult volunteers asked to repeat the same movement over and over became significantly faster when asked to repeat that movement on demand—a result that occurred not because they anticipated the movement, but because of an as yet unknown mechanism that prepared their brains to replicate the same action.
A Johns Hopkins expert panel of health care providers and patients have announced what is, to their knowledge, the nation’s first set of operation-specific opioid prescribing guidelines. The guidelines are based on the premise that opioid prescribing limits should be based on the operation performed rather than a blanket approach. The ranges offered for each of 20 common operations generally call for reductions from the current rates of opioid prescription, and the researchers say that patients themselves favor using less of the drugs than physicians often prescribe.
Johns Hopkins Medicine researchers say a study designed to see if reducing the amount of anesthesia reduces the risk of postoperative delirium in older patients surprisingly found that lighter sedation failed to do so in severely ill people undergoing hip fracture repair.
In a new study, Johns Hopkins researchers found that fewer than half of interviewed caregivers for Baltimore preschool children with asthma were prepared to administer medication for routine management or emergency response to a child's chronic condition.
In the age of Big Data, cancer researchers are discovering new ways to monitor the effectiveness of immunotherapy treatments.
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