The patient-centered medical home (PCMH) is a concept at the heart of many health care reform models that aim to both improve the quality of care and reduce wasteful spending. But a new analysis of federally qualified health centers finds that clinics with higher scores as medical homes also had higher per-patient operating costs.
Researchers from the University of Chicago Medicine argue that parents should be critical stakeholders in the expansion of newborn screening to include lysosomal storage diseases (LSDs).
The University of Chicago Medicine and Silver Cross Hospital's $21.6 million outpatient cancer treatment center in New Lenox will open its doors to patients on Monday, June 25, 2012.
A poll of 150 resident physicians found more than half of had worked with flu-like symptoms at least once in the last year. Nearly 10% believed they’d transmitted an illness to a patient and 20% believed other residents had passed an illness to a patient.
Certain saturated fats that are common in the modern Western diet can initiate a chain of events leading to complex immune disorders in those with a genetic predisposition. This study provides the first plausible mechanism showing step-by-step how Western-style diets contribute to the rapid and ongoing increase in the incidence of inflammatory bowel disease.
The common ancestor of all jawed vertebrates on Earth resembled a shark, according to a new analysis of the braincase of a 290-million-year-old fossil fish that has long puzzled paleontologists.
The University of Chicago Medicine has received an A grade in hospital safety in The Leapfrog Group’s survey of more than 2,600 U.S. hospitals.
Survivors of childhood cancers are at an increased risk of another battle with cancer later in life, according to new research published online June 5 by the Annals of Internal Medicine. In the largest study to date of risk for gastrointestinal (GI) cancers among people first diagnosed with cancer before the age of 21, researchers found that childhood cancer survivors develop these malignancies at a rate nearly five times that of the general population.
The University of Chicago Medicine contributed 21.4 percent of total operating expenses, or $237.1 million, in community benefits to promote health and well-being on the South Side and beyond.
A large pad of abdominal fat cells provides nutrients that promote the spread and growth of ovarian cancer, the fifth leading cause of cancer deaths in women. This fatty tissue, extraordinarily rich in energy-dense lipids, serves as a rich fuel source, enabling cancer cells to multiply rapidly.
A drug treatment has been proven to prevent lesions from cerebral cavernous malformation — a brain blood vessel abnormality that can cause bleeding, epilepsy and stroke — for the first time in a new study. Fasudil shows potential as a valuable new tool in addressing a clinical problem that is currently treatable only with complex surgery.
Young genes that appeared since the primates split from other mammal species are expressed in unique structures of the developing human brain, a new analysis finds. The correlation suggests that scientists studying the evolution of the human brain should look to genes considered recent by evolutionary standards and early stages of brain development.
Chicago will be home to a new $13.75 million project that will apply data mining methods to better understand the genetic and environmental factors behind neuropsychiatric disorders.
A regulatory bias against taking oral anti-cancer medications with food places patients at risk for an overdose and forces them to flush away costly medicines, argues an authority on cancer-drug dosing. It could be safer, more effective and cost-efficient if the cancer drugs that are better absorbed with food were studied and, when appropriate, prescribed to be taken with food.
A new model of obsessive-compulsive disorder (OCD) that mirrors both symptoms of the disease and the timing of its treatment in humans has been created by University of Chicago researchers, according to a new study.
The delivery system for an important class of proteins in the cell membrane can be fully replicated with a mere three components, according to a new study published in Nature.
Pegloticase can produce significant and sustained clinical improvements in many patients with chronic gout that is resistant to conventional therapies. In two clinical trials, pegloticase rapidly lowered high levels of uric acid, the biochemical abnormality in gout. Forty percent of patients had complete resolution of at least one of the painful swollen joint nodules that are a hallmark of severe gout.
The perceived role of God in illness and recovery is a primary influence upon the health care beliefs and behaviors of American Muslims, a first-of-its-kind study has discovered.
Unusually high clustering of last names within Italian academic institutions and disciplines indicates widespread nepotism in the country’s schools, according to a new computational analysis.
A new national collaboration of asthma genetics researchers has revealed a novel gene associated with the disease in African-Americans, and study confirmed the significance of four gene associations reported by a European asthma genetics study.
A GWAS found two genetic variations that predict which patients with Hodgkin's lymphoma are likely to develop radiation-induced second cancers years after treatment. This could help physicians reduce the risks for susceptible patients. Younger patients and those who receive more radiation are most at risk.
Hospitalized patients who had conversations about religion and spirituality with the healthcare team were the most satisfied with their overall care. However, 20 percent of patients who would have valued these discussions say their desires went unmet.
Genetic instructions for developing limbs and digits were present in primitive fish millions of years before their descendants first crawled on to land, University of Chicago researchers have discovered. The result suggests that the recipe for limb development is conserved in species separated by 400 million years of evolution.
A study of more than 1,000 patients with colon cancer that had spread to distant sites found that one in eight was treated with at least one drug regimen that was not recommended. Those patients were exposed to significant risk without proven benefits, at an estimated cost—just for the drugs—of more than $2 million.
The first study of the social and ethical issues associated with a novel treatment for ulcerative colitis has found that most potential patients are eager for what is now called "fecal microbiota transplantation" to become available, although many have concerns about donor selection, screening, and methods of delivery.
Cutting back on sleep drastically reduces a healthy young man's testosterone levels, with a host of negative health effects.
A new comparison of proteins shared across species finds that complex organisms, including humans, have accumulated structural weaknesses that may have actually launched the long journey from microbe to man. The study, published in Nature, suggests that the random introduction of errors into proteins, rather than traditional natural selection, may have boosted the evolution of biological complexity.
Arsenic exposure and smoking each elevate the risk of disease. But when combined together, the danger of dying from cardiovascular disease is magnified, a new study finds.
University of Chicago evolutionary biologist Neil Shubin has been elected a Member of the National Academy of Sciences and honored with a prestigious national teaching award.
The effects of nicotine upon brain regions involved in addiction mirror those of cocaine, according to new neuroscience research. A single 15-minute exposure to nicotine caused a long-term increase in the excitability of neurons involved in reward, according to a University of Chicago study published in The Journal of Neuroscience.
In the largest study of it kind to establish a link between sleep and diabetes, researchers found that people with diabetes who sleep poorly have higher insulin resistance, and a harder time controlling the disease.
In modern ecology, the removal or addition of a predator to an ecosystem can produce dramatic changes in the population of prey species. For the first time, scientists have observed the same dynamics in the fossil record, thanks to a mass extinction that decimated ocean life 360 million years ago.
A new study of older diabetes patients has found that well-controlled blood sugar levels were associated with a lower risk of major complications but the very lowest blood sugar levels were associated with a small but significant increased risk of death.
For some people, alcohol is a social lubricant. For others, it's an unpleasant downer. New research shows that a person's response to alcohol can predict their future drinking behavior, including their frequency of binge drinking and the risk of developing an alcohol-use disorder.
The mystery of biodiversity – how thousands of similar species can co-exist in a single ecosystem – might best be understood as the result of a massive rock-paper-scissors tournament, a new study has revealed.
At its annual cancer symposium, the Society of Surgical Oncology will present the 43rd annual James Ewing Layman's Award to Kimberly T. Duchossois of Barrington Hills, Ill., for her deep commitment and long-term efforts to improve the quality of cancer treatment and help cancer patients get information they need to make wise decisions about their care.
The most popular model used by geneticists for the last 35 years to detect the footprints of human evolution may overlook more common subtle changes, a new international study finds.
Many women who survive breast and gynecologic cancers want medical help for their sexual issues, but most do not get it.
Blocking a factor that can activate the human immune response against intestinal bacteria or certain foods could prevent the development of celiac disease.
Sharon O'Keefe, a nationally recognized authority on hospital operations, health care quality, patient satisfaction and employee engagement, has been named President of the University of Chicago Medical Center, effective February 23, 2011.
Male splendid fairy-wrens, a sexually promiscuous small bird native to Australia, are known to sing a special song each time they hear the call of one of their predators, the butcherbirds. New research from the University of Chicago finds that this seemingly dangerous behavior actually serves as a call to potential mates – a flirtation using fear.
A SCUBA expedition in Australia and New Zealand to find the rare embryos of an unusual shark cousin enabled American and British researchers to confirm new developmental similarities between fish and mammals. The study confirms that organisms separated by hundreds of millions of years of evolution share similar genetic programs for body formation.
Although the 2009 H1N1 influenza pandemic infected an estimated 60 million people and hospitalized more than 250,000 in the United States, it also brought one significant benefit—clues about how to make a vaccine that could protect against multiple strains of influenza.
New genes that have evolved in species as little as one million years ago – a virtual blink in evolutionary history – can be just as essential for life as ancient genes, startling new research has discovered. The University of Chicago study challenges evolutionary biology assumptions about the importance of new genes in development.
The performance of a brain-machine interface designed to help paralyzed subjects move objects with their thoughts is improved with the addition of a robotic arm providing sensory feedback, a new study from the University of Chicago finds.
A two-day conference at the University of Chicago Medical Center is designed to offer surgeons a peek at the profession's future. It focuses on new molecular and mechanical solutions to three age-old problems: preventing the breakdown of anastomoses, improving tissue healing after surgery and developing new tools to test and sharpen surgical skills.
Black, Asian, and Native American children are more likely than white and Hispanic children to die after being treated for neuroblastoma, according to new research on the pediatric cancer. The study is the largest ever to look at racial disparities in risk and survival for the most common solid cancer found in young children.
Cutting back on sleep reduces the benefits of dieting. When dieters got a full night's sleep, half of the weight they lost was fat. When they cut back on their sleep, only one-fourth of their weight loss came from fat. Sleep-deprived dieters also produced higher levels of ghrelin, a hormone that triggers hunger and reduces energy expenditure.
First randomized clinical trial to compare treatments; patient's mother: "It works." An anorexia nervosa treatment strategy that promotes parental involvement in restoring an adolescent to healthy weight and eating habits is more effective than traditional individual-based anorexia nervosa therapy, according to new research.
Greater numbers of depression, anxiety, oppositional defiant disorder, and conduct disorder symptoms at ages 4 to 6 among children with ADHD robustly predicted risk for depression during adolescence.
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