University of Utah neuroscientists report that when a region of the brain called the lateral habenula is chronically inactivated in rats, they repeatedly drink to excess and are less able to learn from the experience. The study, published online in PLOS ONE on April 2, has implications for understanding behaviors that drive alcohol addiction.
About 6 percent of colorectal cancers are diagnosed within three to five years after the patient receive a clean colonoscopy report, according to researchers from Huntsman Cancer Institute (HCI) at the University of Utah.
Compared to 10 years ago, sequencing the human genome has plummeted in cost by 1 million-fold and can be completed in a fraction of the time. Yet there are still barriers preventing DNA sequence information from routinely being incorporated into patient care. The USTAR Center for Genetic Discovery is partnering with California based Omicia, Inc. to make patient genome analysis as routine as a blood test.
University of Utah Health Care neurosurgeon, Meic Schmidt, MD, MBA, has been recognized as one of the world’s top five experts in spine tumor treatment, according to a recent ranking by Expertscape.
Study with mice shows moderate exercise can activate Nrf2, leading to stem cell regeneration.
March 17 stop in Utah is part of national lecture series organized by non-profit group CURE to raise awareness about epilepsy.
Newly released statistics show that more patients are turning to the University of Utah for liver transplant services. While the U.’s liver transplant program is one of the youngest in the region, it has established itself as among the most successful. In 2013, the University of Utah performed the most liver transplants in the state, with 35 patients undergoing life-saving procedures at the U.
Researchers report two breakthroughs in understanding pancreatic cancer: the development of the first mouse model that simulates a precursor lesion called intraductal papillary mucinous neoplasia (IPMN), and the identification of an enzyme, Brg1, that appears to help cause the formation of IPMN lesions while also suppressing another precursor lesion.
A national poll from Utah’s Huntsman Cancer Institute shows 34 percent of respondents would not seek genetic testing to predict likelihood of developing a hereditary cancer. The poll shows 35 percent of respondents would be extremely or very likely to seek aggressive prophylactic or preventive treatment.
The project’s first initiative revolves around studying the brains of people who have returned from serving missions on behalf of the Church of Jesus Christ of Latter-day Saints.
A University of Utah-led study for treatment of patients with atrial fibrillation (A-fib) provides strong clinical evidence for the use of 3-D MRI to individualize disease management and improve outcomes.
Researchers from Huntsman Cancer Institute (HCI) at the University of Utah discovered a cellular mechanism that drives the spread of breast cancer to other parts of the body (metastasis), as well as a therapy which blocks that mechanism.
Cells with a mutation in the gene called K-Ras—found in close to 30 percent of all cancers , but mostly those with worst prognosis, such as pancreatic cancer, colon cancer, and lung cancer—subvert the normal mechanisms of cell death.
University of Utah researchers have discovered a naturally occurring genetic variation in mice that predisposes carriers toward developing severe, inflammatory arthritis.
When people understand privacy safeguards, they approve of tissues being used for population-based research without their consent, innovative study finds.
Three University of Utah faculty members whose research has resulted in major disease-related discoveries, patents, inventions, and startup companies have been named fellows of the National Academy of Inventors (NAI).
New technique by Dr. Amit Patel uses a minimally invasive technique where he goes backwards through a patient’s main cardiac vein, or coronary sinus, and inserts a catheter. He then inflates a balloon in order to block blood flow out of the heart so that a very high dose of gene therapy can be infused directly into the heart. The unique gene therapy doesn’t involve viruses and is pure human DNA infused into patients. The DNA, called SDF-1, is a naturally occurring substance in the body that becomes a homing signal for a patient’s body to use its own stem cells to go to the site of an injury.
For the past 10 years, U.S. clinicians have been performing unnecessary Pap tests for cervical cancer screening in certain groups of women, according to a researcher from Huntsman Cancer Institute (HCI) at the University of Utah.
The recent identification of brown fat stem cells in adult humans may lead to new treatments for heart and endocrine disorders, according to a new University of Utah study published in the journal Stem Cells.
Isoforms of PDE3A enzyme might make targets for drugs that prevent SDC while still helping the heart pump blood
David Classen, M.D., Ph.D., an associate professor of medicine and consultant of infectious diseases at the University of Utah School of Medicine, will be honored in December for a lifetime of achievement related to improving patient safety.
June L. Round, Ph.D., has been named one of the nation's "most innovative young scientists and engineers" in the 2013 Packard Fellowships in Science and Engineering program.
Previous studies have identified links between women’s prepregnancy body mass index (BMI) and pregnancy weight gain to an increased risk for the development of autism spectrum disorders (ASD) in children. But in the new study from University of Utah, researchers build on prior research by identifying an association between autism spectrum disorder risk and prenatal weight gain, after accounting for important related factors such as a woman’s prepregnancy BMI.
For people with a family history of adenomas (colon polyps that lead to colon cancer), up to 10 percent of colorectal cancers could be missed when current national screening guidelines are followed.
The goal of the Sojourn Awards is to promote innovations by inspiring health care workers and to invest in their futures. Holli Martinez will be recognized along with recipients from Idaho, Oregon and Washington who have worked to advance the access, quality and understanding of palliative care.
University of Utah researchers have found that deficiency of an antioxidant response protein called nuclear erythroid-2 like factor-2 (Nrf2) delays or prevents hypertrophic cardiomyopathy.
University of Utah Center for Clinical and Translational Science has been selected to receive a $20.4 million grant from the National Institutes of Health. The grant will allow the Center to provide support for all aspects of translational research over the next five years.
CureSearch for Children’s Cancer this week awarded researchers at Huntsman Cancer Institute at the University of Utah a $1.73 million grant to test a novel targeted treatment for Ewing sarcoma that hopefully will disrupt the cancer’s growth and spread.
Adam Frost, M.D., Ph.D., a professor of biochemistry, and Ryan O’Connell, Ph.D., an assistant professor of pathology, were selected to receive the NIH Director's New Innovator Award from a competitive, national field of researchers.
Craig H. Neilsen exemplified the extraordinary success and quality of life one can achieve after experiencing a life-changing spinal cord injury (SCI).
The University of Utah on Friday, Aug. 23, 2013, broke ground on the $36.4 million Ray and Tye Noorda Oral Health Education Building, which when completed in December 2014 will house the University’s new School of Dentistry.
Chapman, a noted scholar and researcher, will lead the University of Utah's Department of Biomedical Informatics as the school’s new chair effective Sept. 1.
University of Utah and George E. Wahlen Department of Veterans Affairs Medical Center researchers have developed a mathematical model to help answer critical questions and guide the response to an anthrax exposure.
Newly released research findings from University of Utah neuroscientists assert that there is no evidence within brain imaging that indicates some people are right-brained or left-brained. For years in popular culture, the terms left-brained and right-brained have come to refer to personality types, with an assumption that some people use the right side of their brain more, while some use the left side more. Following a two-year study, University of Utah researchers have debunked that myth through identifying specific networks in the left and right brain that process lateralized functions.
Children born with non-chromosomal birth defects have a twofold higher risk of cancer before age 15, compared to children born without birth defects.
When a child is diagnosed with cancer, one of the first questions the parents ask is “Will my other children get cancer?” A new study from Huntsman Cancer Institute (HCI) at the University of Utah suggests the answer to that question depends on whether a family history of cancer exists.
The study, formally titled, “Optimal Germinal Center B Cell Activation and T-Dependent Antibody Responses Require Expression of the Mouse Complement Receptor Cr1” used a mouse model system to examine receptors on a select set of cells that centralize antigens in sites of high immune activity, which are substances that cause a person’s immune system to produce antibodies. Among their discoveries was a finding that cells that are central to organizing the centers for B cells (which are antibody-producing cells) express a receptor called Cr1 when undergoing processes to make antibodies.
Citing his groundbreaking contributions to understanding the evolving role of platelets, the American Society of Hematology (ASH) has awarded University of Utah professor of medicine Andrew S. Weyrich, Ph.D., the 2013 Dameshek Prize.
When U.S. physicians prescribe antibiotics, more than 60 percent of the time they choose some of the strongest types of antibiotics, referred to as “broad spectrum,” which are capable of killing multiple kinds of bacteria, University of Utah researchers show in a new study.
Electroconvulsive therapy (ECT) has long been considered the most effective treatment of medication-resistant depression. But millions of people don’t take advantage of it because of the side effects and misperception of the therapy.
University of Utah professor and chair of neurosurgery, William T. Couldwell, M.D., Ph.D., has been named the 2013-2014 president of the American Association of Neurological Surgeons (AANS).
An internationally regarded researcher and highly honored dental educator, Rena N. D’Souza, D.D.S., M.S., Ph.D., has been selected as the first permanent dean of the University of Utah’s School of Dentistry. She assumes her new role on Aug.1, 2013.
The University of Utah today announced that Patricia G. Morton, R.N., Ph.D. — a nationally known expert in nursing education, critical care and cardiovascular nursing —will lead its College of Nursing as dean.
University of Utah researchers discovered that over the past 10 years children received more solid organ transplants and fewer children died waiting for a life-saving transplant.
Research conducted by the Pelvic Floor Disorders Network, an initiative funded by the National Institutes of Health, has revealed that the long-term success rates of a surgery to treat pelvic organ prolapse are lower than expected.
The Patient-Centered Outcomes Research Institute (PCORI) has approved a $1.9 million research award to the University of Utah to study asthma in children and how better monitoring of the disease could improve health.
While the genes provided by the father arrive at fertilization pre-programmed to the state needed by the embryo, the genes provided by the mother are in a different state and must be reprogrammed to match.
A gene mutation associated with a rare sleep disorder surprisingly also contributes to debilitating migraines, a new discovery that could change the treatment of migraines by allowing development of drugs specifically designed to treat the chronic headaches.
Researchers from Huntsman Cancer Institute (HCI) at the University of Utah have developed a novel and powerful technique to identify the targets for a group of enzymes called RNA cytosine methyltransferases (RMTs) in human RNA.
James Chen-tson Fang, M.D., has been named chief of cardiovascular medicine at the University of Utah School of Medicine and director of the cardiovascular service line at University of Utah Health Care.
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