Hematologist John Sweetenham, M.D., has been appointed Senior Director of Clinical Affairs and Executive Medical Director at Huntsman Cancer Institute (HCI), and Professor in the Department of Medicine at the University of Utah.
The University of Utah School of Medicine has named 20 physicians and scientists as inaugural fellows in the University of Utah Academy of Medical Science Educators.
The lack of very long chain fatty acids does not cause blindness in children with the incurable eye disease known as Stargardt type 3 retinal degeneration.
Inhibition of the protein known as adenosine diphosphate ribosylation factor 6 (ARF6) reduces the spread of melanoma to the lungs in mice, according to a study published in the March 5 issue of Science Signaling online.
An estimated 300,000 U.S. patients get surgical site infections every year, and while the causes are varied, a new University of Utah study suggests that some who get an infection can blame it partly on their genes.
Geneticists led by University of Utah Nobel Prize Laureate Mario R. Capecchi, Ph.D., have engineered mice that develop clear cell sarcoma (CCS), a significant step in better understanding how this rare and deadly soft tissue cancer arises.
University of Utah (the U) researchers, in collaboration with several groups from around the country, published a paper on Monday, Jan. 14, 2013, following one of the biggest studies of its kind, that extends our understanding of genes related to autism spectrum diseases (ASDs) and advances methods for early detection and treatment.
Researchers have discovered that adding lovastatin, a widely used cholesterol-lowering drug, to traditional antimalarial treatment decreases neuroinflammation and protects against cognitive impairment in a mouse model of cerebral malaria.
As the prescribed use of buprenorphine has dramatically increased in recent years, accidental exposure of children to the drug has risen sharply, placing them at risk for serious injury, and in extremely rare cases even death.
People who reside in rural areas of Utah are less likely to follow colorectal cancer (CRC) screening recommendations than their urban counterparts, according to researchers from Huntsman Cancer Institute (HCI) at the University of Utah.
Health care consumers considering a physician at University of Utah Health Care now have an additional tool— online access to the system’s patient satisfaction scores and comments. The rankings are based on more than 40,000 patient surveys and evaluate physicians on nine questions.
Huntsman Cancer Institute (HCI) researchers Michael Deininger, M.D., Ph.D., and Thomas O’Hare, Ph.D., were part of a team that found a potent oral drug, ponatinib, effective in patients who have developed resistance to standard treatments for chronic myeloid leukemia (CML) and Philadelphia chromosome positive acute lymphoblastic lymphoma (Ph+ ALL). The New England Journal of Medicine released results of the trial today.
Discovery of a new drug with high potential to treat Ewing sarcoma, an often deadly cancer of children and young adults, and the previously unknown mechanism behind it, come hand-in-hand in a new Huntsman Cancer Institute (HCI) study.
A new discovery concerning a fundamental understanding about how DNA works will produce a “180-degree change in focus” for researchers who study how gene packaging regulates gene activity, including genes that cause cancer and other diseases.
University of Utah medical researchers have identified a way to treat inflammation while potentially minimizing a serious side effect of current medications: the increased risk for infection.
Genetic test results for Lynch syndrome often prove inconclusive, but two new studies show that two-thirds to three-fourths of genetic variants can be classified into categories that indicate the most appropriate screening and treatment guidelines.
Researchers from the University of Utah report that a cell-to-cell communication network known as the Wnt signaling pathway plays an important role in both the production and specialization of nerve cell precursors in the hypothalamus.
For the first time, a mutation in HIF2α, a specific group of genes known as transcription factors that is involved in red blood cell production and cell metabolism, has been identified in cancer tumor cells.
Using advanced computer simulations, University of Utah College of Pharmacy researchers have produced moving images of a protein complex that is an important target for anti-cancer drugs.
Poxviruses, which are responsible for smallpox and other diseases, can adapt to defeat different host antiviral defenses by quickly and temporarily producing multiple copies of a gene that helps the viruses to counter host immunity.
University of Utah Department of Medicine researchers have received $16 million from the National Institutes of Health (NIH) to set up a translational research center to study the cellular and molecular causes of blood clots.
A new study of the genetic makeup, or genome, of Ewing sarcoma, a rare cancer that strikes children, teenagers, and young adults, has produced multiple discoveries, including genetic factors related to long-term survival.
Women battling stubborn major depression may have a surprising new ally in their fight—the muscle-building dietary supplement creatine.
Researchers at the University of Utah Departments of Neurology and Human Genetics, in collaboration with researchers at Duke University Medical Center, have discovered that mutations in the ATP1A3 gene cause the disease in the majority of patients with a diagnosis of AHC.
The velvety voice of Elvis Presley still makes hearts flutter—and in a new study with people who have the rare genetic disorder Williams syndrome, one of the King’s classics is among a group of songs that helped to cast light on part of the essence of being human: the mystery of emotion and human interaction.
Research into how carbohydrates are converted into energy has led to a surprising discovery with implications for treating a perplexing and potentially fatal neuromuscular disorder and possibly even cancer and heart disease.
Scientists from the University of Utah have discovered that a mouse protein called IFITM3 contributes to defense against some types of viral infections by binding to an enzyme responsible for regulating the pH of a cell’s waste disposal system.
Mutations in a gene called XRCC2 cause increased breast cancer risk, according to a study published today in the American Journal of Human Genetics. The study looked at families that have a history of the disease but do not have mutations in the currently known breast cancer susceptibility genes.
Researchers from Huntsman Cancer Institute (HCI) at the University of Utah report they have discovered a method to identify cancer-causing rearrangements of genetic material called chromosomal translocations quickly, accurately, and inexpensively.
A team of scientists from the University of Utah and the University of California at San Francisco has discovered that the mutation of a gene encoding a ketone body transporter triggers accumulation of fat and other lipids in the livers of zebrafish.
Researchers from the University of Utah have identified a process by which the most common types of urinary tract infection-causing bacteria are able to trigger bladder cell shedding and disable immune responses.
The biologic and genetic mechanisms controlling the formation and function of the CCS are not well understood, but new research with mice shows that altered function of a gene called Tbx3 interferes with the development of the CCS and causes lethal arrhythmias.
The Huntsman Cancer Institute (HCI) at the University of Utah has been named a National Cancer Institute Center for Quantitative Imaging Excellence (CQIE).
University of Utah cardiologist Dean Y. Li, M.D., Ph.D., a groundbreaking researcher in vascular development and disease, has been named the inaugural vice dean for research and chief scientific officer at University of Utah Health Care.
A team of researchers from the University of Utah and the University of Massachusetts has identified the first gene associated with frequent herpes-related cold sores.
Researchers from Huntsman Cancer Institute (HCI) at the University of Utah have discovered a way to model human breast cancer that could lead to new tools for predicting which breast cancers will spread.
Two University of Utah researchers are teaming up with the Department of Defense to investigate the long-term affects of Traumatic Brain Injury in U.S. soldiers returning from Iraq and Afghanistan.
Academic medical centers (AMCs) must make systematic changes to improve quality of life—and thus productivity—of their faculty, according to a commentary that will appear in the Oct. 12, 2011, issue of Science Translational Medicine.
World-renowned University of Utah medical geneticist John M. Opitz, M.D., to receive 2011 William Allan Award in Human Genetics for pioneering work identifying and understanding genetic syndromes. His seminal role in phenotyping, identifying new syndromes laid the foundation for clinical genetics.
This is the third straight year a University of Utah researcher has received the prestigious honor. Brenda Bass is recognized for having made substantial discoveries involving dsRNA over the past 25 years.
In a first of its kind study, researchers have found that using two way audio-video telemedicine to deliver stroke care, also known as telestroke, appears to be cost-effective for rural hospitals that don’t have an around-the-clock neurologist, or stroke expert, on staff.
New research from the University of Utah in collaboration with the Utah Department of Health (UDOH) shows that the presence or absence of intellectual disability (ID) and autism spectrum disorders (ASD) is not related to household income.
A team of researchers from the University of Utah and Brigham Young University has developed a mouse model of focal dermal hypoplasia, a rare human birth defect that causes serious skin abnormalities and other medical problems. This animal model not only provides insight into studying the cause of focal dermal hypoplasia (FDH), but also offers a novel way to study a signaling pathway that is crucial for embryonic development.
University of Utah Health Care is the No. 1 health care system in the Salt Lake City metro area, according U.S. News & World Report’s 2011-2012 Best Hospitals rankings.
Beginning July 1, 2011, Vivian S. Lee, M.D., Ph.D., M.B.A., an accomplished MRI radiologist and scientist, will bring her considerable abilities as a physician-scientist and administrator to the University of Utah (the U) as the new senior vice president for health sciences.
Researchers working with zebrafish at Huntsman Cancer Institute (HCI) at the University of Utah have identified previously undiscovered high-risk genetic features in T-cell acute lymphocytic leukemia (T-ALL)
New findings from University of Utah School of Medicine researchers show that the retrovirus called XMRV is not present in the blood of patients who have chronic fatigue syndrome (CFS). These findings contradict a widely reported 2009 Science study that linked CFS to XMRV.
A new book by University of Utah School of Medicine faculty Robert E. Jones, M.D., FACP, FACE, and Kathleen B. Digre, M.D., take an in-depth look at diabetes and provide a practical approach for health care providers caring for women with the disease.
Researchers have found that a synthetic version of hypericin, a compound naturally found in St. John’s wort, may be a promising treatment for patients with recurrent malignant brain tumors. Their findings were published online on March 31, 2011 in the journal Cancer.
University of Utah School of Medicine researchers have found compelling evidence that Parkinson’s disease is associated with an increased risk of prostate cancer and melanoma, and that this increased cancer risk also extends to close and distant relatives of individuals with Parkinson’s disease .
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