Margaux Mustian and Laura Hickman say they pursued a career in transplant surgery in part due to the teaching and training they received from longtime UAB transplant surgeon Mark Deierhoi.
Hengbin Wang and colleagues describe a key role for a protein called RSF1 in silencing genes. Besides the molecular biology details, the researchers also showed that disruption of RSF1 expression in the embryos of African clawed frogs caused severe developmental defects in the tadpoles.
For 21 years, the National Science Foundation has supported summer undergraduate research at UAB. The 10 students at UAB this summer came from schools as far-flung as San Diego State and Brigham Young universities and the University of Florida.
Biomedical engineering researchers will attack two banes of cardiovascular disease — heart failure after heart attacks and the scourge of resistant high blood pressure — with $4.8 million in National Institutes of Health grants that begin this fall.
Alexa Wade’s passion for research started with a strawberry. Michael Vivian’s started while watching “Star Trek” episodes with his dad. Cameron LaFayette’s began in eighth grade from the movie “Gifted Hands,” the saga of Detroit-born neurosurgeon Ben Carson.
Alex City, Alabama, dentist George Hardy will star in the premiere of the short film “Texas Cotton” this week at the Birmingham Sidewalk Film Festival. Hardy has become an icon among cult-movie enthusiasts for his turn in “Troll 2” and the subsequent documentary “Best Worst Movie.” While “Troll 2” has been universally panned, Hardy embraces the film as “one of the best things that’s ever happened to me.”
A screening program conducted by University of Alabama at Birmingham Callahan Eye Hospital ophthalmologists is helping cut negative outcomes from ROP in infants by half.
An intracellular metabolite of glutamine regulates cellular differentiation programs by changing the DNA-binding patterns of a transcription factor and by altering genome interactions. Genome context near the binding sites affects whether the binding turns on or turns off gene programs.
Undergraduate summer research fellowships let students pursue their passions. Daniel Craven used a BioBots three-dimensional bioprinter to make small polymer scaffolds that can hold cells for tissue engineering. The scaffolds, less than half an inch thick, are biocompatible and biodegradable.
Researchers have created a small molecule that prevents or impedes tooth cavities in a preclinical model. The inhibitor blocks the function of a key virulence enzyme in an oral bacterium, a molecular sabotage that is akin to throwing a monkey wrench into machinery to jam the gears.
• Birmingham committed to the “90:90:90” principle, whereby 90 percent of people living with HIV will know their HIV status, 90 percent of those who know their status will be engaged with clinical care and on anti-HIV therapy, and 90 percent of those on treatment will achieve full viral suppression
• Paris Declaration confirms 13th city to commit to being a Fast-Track City in the effort to end the spread of HIV/AIDS
• HIV/AIDS research powerhouse, UAB stands behind commitment of city to end the spread of the disease
Men and older stroke patients in the southeastern United States, known as the stroke belt, were less likely to receive statins, stroke-preventing medication, than were women and younger patients.
The REasons for Geographic and Racial Differences in Stroke Study found there is not a difference between races’ receiving statins.
Trends in statin prescriptions differ across the United States.
UAB School of Education experts provide some tips to parents on how to ease the back-to-school transition for children with special needs and emotional and behavioral disorders.
For 21 years, the National Science Foundation has supported summer undergraduate research at UAB. The 10 students at UAB this summer came from schools as far-flung as San Diego State and Brigham Young, and as different in size as Oakwood University and the 52,000-student University of Florida.
A brain penetrant drug — a small-molecule mimetic of BDNF, or brain derived neurotrophic factor — is able to improve brain performance in Rett syndrome mice — specifically synaptic plasticity in the hippocampus and object location memory. The hippocampus is involved in learning and memory.
Pediatric neurosurgeons, oncologists and molecular imaging physicians continue to work toward better diagnoses, treatments and cures for childhood cancer.
A collaborative team of neuro-oncology surgeon/scientists has discovered a previously unidentified molecular mechanism that maintains glioma stem cells, and they have tested it as a potential therapeutic target in glioblastoma, using a small molecule inhibitor they designed and synthesized.
A UAB physician will co-chair a steering committee of global cystic fibrosis experts and clinical trial investigators to support the design, conduct and execution of the triple combination pivotal study program.
Even if you’ve previously rejected vaccinating your children or have neglected to do so, physicians say it’s not too late to protect them against many preventable diseases.
University of Alabama at Birmingham director of the Regions Institute for Financial Education Stephanie Yates, Ph.D., provides insight into how parents can use budgeting to plan and save on back-to-school items this fall.
A UAB obstetric surgeon will lend her skills to African women by treating obstetric fistula, a common complication of childbirth in the developing world that causes incontinence.
The UAB study could help inform future health care management during early life and the development of interventions aimed at improving quality of life for older individuals.
A new method improves the high-yield, -purity and -activity purification of complex proteins by 10- to 500-fold, with crucial advantages for researchers and the pharmaceutical industry as potentially the most efficient and universal tool for high-throughput studies of significant biological systems.
Researchers have developed micro-cubes that can sponge up a hydrophobic anti-cancer drug and deliver it to cancer cells. Tissue culture tests show these tiny, porous cubes, loaded with the hydrophobic drug, are more potent against liver cancer cells and less harmful to normal liver cells.
A new study shows that teens communicating on mobile phones with friends show stronger signs of technology addiction than when communicating with parents.