Researchers have found that a synthetic version of hypericin, a compound naturally found in St. John’s wort, may be a promising treatment for patients with recurrent malignant brain tumors. Their findings were published online on March 31, 2011 in the journal Cancer.
University of Utah School of Medicine researchers have found compelling evidence that Parkinson’s disease is associated with an increased risk of prostate cancer and melanoma, and that this increased cancer risk also extends to close and distant relatives of individuals with Parkinson’s disease .
University of Utah cardiologist Roger Freedman will collect heart rate and blood oxygen information about Apa Sherpa during the climber's 21st ascent of Mt. Everest.
Surgeons at University of Utah Hospital have performed the hospital’s first implant of a new-generation left ventricular assist device (LVAD) using the HeartWare HVAD.
To help adult survivors of childhood cancer manage the unique long-term consequences of their treatment, Huntsman Cancer Institute (HCI) at the University of Utah has created the Pediatric Cancer Late Effects Clinic.
Researchers at the University of Utah’s Comprehensive Arrhythmia and Research Management (CARMA) Center have found that delayed-enhancement magnetic resonance imaging (DE-MRI) holds promise for predicting the risks of strokes, the third leading cause of death in the U.S.
The vast majority of parents who tested positive for a genetic mutation that increases the risk of melanoma (the most serious form of skin cancer) support genetic testing of their children or grandchildren.
Researchers at the Huntsman Cancer Institute have discovered a trigger mechansim that monitors whether a cells nucleus has the proper structure for cell division,
University of Utah (U of U) medical researchers have uncovered a wiring diagram that shows how the brain pays attention to visual, cognitive, sensory, and motor cues. The research provides a critical foundation for the study of abnormalities in attention that can be seen in many brain disorders such as autism, schizophrenia, and attention deficit disorder.
Just seven months after University of Utah geneticists took part in a landmark study that sequenced for the first time the genome of an entire Utah family, U of U researchers have taken part in another historic study that is the first large-scale genome sequencing project – 179 people representing three continents – and 60 Utahns played a major role in this study, too.
University of Utah (U of U) medical researchers have made an important step in diagnosing autism through using MRI, an advance that eventually could help health care providers identify the problem much earlier in children and lead to improved treatment and outcomes for those with the disorder.
University of Utah Health Care has achieved the No. 1 ranking in University HealthSystem Consortium’s 2010 Quality and Accountability Study.
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have discovered that a protein, zyxin, is necessary for the maintenance and repair of the cell’s cytoskeleton, or internal framework, which serves as the muscle and bone of the cell.
Researchers at Huntsman Cancer Institute at the University of Utah demonstrate in a study featured today in Cell the mechanism by which mutation of the APC gene affects a cellular process known as DNA methylation.
The risk for suicide increases by nearly one-third at elevations of 6,500 feet or higher, neuroscientists from the University of Utah report in a new study.
Following up a 2007 proof-of-concept study, a University of Utah biochemist and colleagues have developed a promising new anti-HIV drug candidate, PIE12-trimer, that prevents HIV from attacking human cells.
Severe trauma to the head and spine resulting from all-terrain vehicle (ATV) accidents are increasing dramatically, with an estimated cost of $3.24 billion, according to research released today from the University of Utah Department of Neurosurgery.
Using an experimental mouse model for malaria, an international group of scientists has discovered that adding antioxidant therapy to traditional antimalarial treatment may prevent long-lasting cognitive impairment in cerebral malaria.
In the ongoing effort to understand the growing prevalence of autism spectrum disorders (ASDs) nationwide, the University of Utah has received a $2.4 million, four-year grant to estimate the number of Utah 8-year-olds with ASDs.
With the generous support of Families of Spinal Muscular Atrophy, researchers in the University of Utah Department of Neurology are making significant headway in the fight against the disease. Once very poorly understood, SMA is now considered one of the genetic conditions closest to finding an effective treatment.
An international consortium of researchers from more than 70 universities, including the University of Utah, has reported that a study of nearly 2,300 people supports the growing consensus that autism is caused in part by rare genetic changes called copy number variants (CNVs).
In a surprising discovery that someday may lead to new treatments for many inflammatory diseases, University of Utah scientists found that a hormone involved in iron metabolism can save mice from deadly acute inflammation.
A Nobel Prize-winning University of Utah geneticist discovered that bone marrow transplants cure mutant mice who pull out their hair compulsively. The study provides the first cause-and-effect link between immune system cells and mental illness, and points toward eventual new psychiatric treatments.
Dr. Marcos Daccarett, an assistant professor at the University of Utah School of Medicine, won the Young Investigator Award at the Heart Rhythm Society’s (HRS) annual scientific sessions in Denver, May 12-15.
A multi-institution team led by a University of Utah (U of U) USTAR researcher has found that the brain gene STX1A plays a significant role in the level of intelligence displayed by patients with Williams Syndrome (WS).
University of Utah Hospital is the second center in the country to implant a patient with a Utah-made Ventricular Assist Device (VAD).
Unique cooperation between four Utah heart centers makes UTAH Cardiac Program one of the country's most successful transplant programs.
Utah children and adolescents suffering from psychiatric conditions have one thing in common – the excellent care they receive from physicians who are graduates of the University of Utah Department of Psychiatry’s Child and Adolescent Training Program. The program, the only one of its kind in the Intermountain West, will mark its 50th anniversary this month with events to honor the founders and current leaders of the program, as well as a special presentation by a nationally recognized leader in training child and adolescent psychiatrists.
How do fruit flies get high cholesterol and become obese? The same way as people do – by eating a diet that’s too rich in fats.
An international coalition of physicians and scientists, led by Huntsman Cancer Institute (HCI) at the University of Utah, has proposed guidelines for the first time concerning genetic testing for melanoma patients.
A pioneering model that a University of Utah cardiologist proposes as a cause of heart disease is the kind of creative thinking the National Institutes of Health (NIH) likes to see—and reward with one of its most prestigious honors, a $2.5 million 2009 Pioneer Award.
Researchers at the University of Utah and Columbia University have reported that a type of virus known to cause leukemia and sarcomas in animals has been found for the first time in malignant human prostate cancer cells.
Researchers at Huntsman Cancer Institute (HCI) at the University of Utah have shed new light on Ewing’s sarcoma, an often deadly bone cancer that typically afflicts children and young adults. Their research shows that patients with poor outcomes have tumors with high levels of a protein known as GSTM4, which may suppress the effects of chemotherapy. The research is published online today in the journal Oncogene.
A specific genetic region that has been increasingly identified as the strongest genetic link to psoriasis has an even more significant role in the chronic skin disease than has been suspected.
The University of Utah College of Pharmacy, joined by friends, supporters, members of The ALSAM Foundation, and Mr. and Mrs. L.S. Skaggs, broke ground Tuesday, Aug. 11, 2009, on a $69-million research facility to be known as the L.S. Skaggs Pharmacy Institute.
University of Utah researchers and their colleagues have identified the gene that is mutated in a hereditary form of a rare neuroendocrine tumor called paraganglioma (PGL). The gene, called hSDH5, is required for activation of an enzyme complex that plays a critical role in the chemical reactions that take place within cells to convert biochemical energy into usable energy.
Disturbed calcium signaling may play a critical role in brain cell degeneration
Hundreds of dignitaries, employees, donors, and community members attended the ribbon cutting for the University of Utah Hospital $200 million expansion on Thursday, July 16, 2009.
University of Utah Health Care today celebrated the opening of the first integrated electrophysiology (EP) MRI laboratory in North America. Located in the University of Utah Hospital, the lab will accelerate the work of University physicians and researchers in diagnosing and treating atrial fibrillation (AF).
Children who are firstborn or breech or whose mothers are 35 or older when giving birth are at significantly greater risk for developing an autism spectrum disorder, University of Utah School of Medicine researchers have reported in a new study with Utah children.
A team of researchers from the University of Utah, Salt Lake city-based Q therapeutics Inc., and The John Hopkins University School of Medicine is collaborating on a stem cell therapy to fight amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.
University of Utah researchers have found that delayed-enhancement magnetic resonance imaging (DE-MRI) holds promise for predicting treatment outcomes and measuring disease progression for patients with atrial fibrillation (AF), a little known heart rhythm disorder that affects more than 3.5 million Americans and causes more than 66,000 deaths a year. Their latest study on a novel application of this technology for AF appears in the April 7 issue of the journal Circulation.
In this week's open-access journal PLoS Biology, research teams at the University of Utah John A. Moran Eye Center and the University of Colorado at Boulder report technical advances that have reduced the time it takes to process high-speed "color" ultrastructure mapping of brain regions down to a few months.
When locked in mortal combat with infection, some mature white blood cells literally cast a DNA net"”called a neutrophil extracellular trap (NET)"”that captures and kills bacteria invading the human body. But the ability to form this "death" NET is missing in the white blood cells of newborn infants, born either at term or prematurely.
Twenty years after first being assessed in a long-term autism study, 41 Utahns with the disorder had a higher social outcome than those in similar studies, University of Utah psychiatry researchers have reported in the journal Autism Research online.
University of Utah nursing students, faculty, and administrators gathered today to say a temporary goodbye to their college's 40-year-old building. The faculty and staff of the nationally ranked college are moving out of the building for 18 months while it undergoes a $23 million renovation to update teaching facilities and provide more space to train nurses.
Researchers at the University of Utah are enrolling people in a new clinical trial that uses a patient's own stem cells to treat ischemic and non-ischemic heart failure.
The mysterious process that orchestrates cells to move in unison to form human and animal embryos, heal wounds, and even spread cancer depends on interaction between two well-known genetic signaling pathways, two University of Utah medical school researchers have discovered.
Researchers at Huntsman Cancer Institute (HCI) believe they may be one step closer to understanding how certain forms of colon cancer develop. The results of a study involving siblings who have been diagnosed with colon cancer are published in the Nov. 1, 2008 issue of Cancer Research.
University of Utah researchers have developed a magnetic resonance imaging (MRI)-based method for detecting and quantifying injury to the wall of the heart's left atrium in patients who have undergone a procedure to treat atrial fibrillation. The results of the study are published in the Oct. 7, 2008, issue of the Journal of the American College of Cardiology.
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