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A multidisciplinary research team at Stony Brook University has received a five-year $3.8 million grant from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, to develop new drugs for pain, inflammation, and potentially drug addiction. The drug development strategy is based on their discovery of intracellular transporters known as FABPs (fatty acid binding proteins) for a neurotransmitter in the body that regulates pain and stress.

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Cancer drugs work because they’re toxic, but that’s also why they afflict healthy cells, producing side effects that can compromise their efficacy. Nobuhide Ueki thinks he may have found a way to get the drugs to selectively target only the cancer cells, and his team’s patent-pending research is the subject of a paper entitled “Selective cancer targeting with prodrugs activated by histone deacetylases and a tumour-associated protease,” to be published on November 5 in Nature Communications.

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In the wake of Sandy, the Oklahoma tornadoes, ubiquitous wildfires and other natural disasters, the National Science Foundation (NSF) recently awarded 12 new grants totaling $32 million through its Interdisciplinary Research in Hazards and Disasters solicitation. The effort, part of NSF's Science, Engineering and Education for Sustainability (SEES) investment, will enable scientists to study ways of predicting and responding to hurricanes, tornadoes, floods, earthquakes, tsunamis, and wildfires.

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Stony Brook University’s (SBU) Center for Inclusive Education (CIE) in the Graduate School and the U.S. Department of Energy’s Brookhaven National Laboratory (BNL) have received a $1.4 million grant from the National Science Foundation to increase the competitiveness of underrepresented minority (URM) PhD students and postdoctoral trainees who are US citizens advancing into STEM careers. This Alliance for Graduate Education and the Professoriate- Transformation (AGEP-T) initiative is called FRAME (Frontiers of Research and Academic Models of Excellence). In the three-year grant period, the project will train 30 graduate students and 12 postdoctoral fellows by providing comprehensive professional preparation that will permit FRAME fellows to compete for and succeed in faculty positions at top research intensive institutions.

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A study on the mechanisms of how plants respond and adapt to elevated levels of carbon dioxide (C02) and higher temperatures has opened a new perspective in climate research. Lead researcher Qiong A. Liu (Alison) of theDepartment of Biochemistry and Cell Biology at Stony Brook University found that elevatedC02 and higher temperatures affect the aspect of gene expression in plants that control flowering time and cell proliferation.

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New research published in Nature and led by Amy Balanoff, a Research Instructor in the Department of Anatomical Sciences, Stony Brook University School of Medicine, provides evidence that dinosaurs evolved the brainpower necessary for flight well before they actually took to the air as birds. “Evolutionary origins of the avian brain” takes a comprehensive look at the so-called “bird brain.” Contrary to the cliché, the term describes a relatively enlarged brain that has the capacity required for flight and was present in one of the earliest known birds, Archaeopteryx.

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Research conducted in six bays of Long Island, NY, and led by scientists from the School of Marine and Atmospheric Sciences at Stony Brook University (SBU) showed that local populations of winter flounder are inbred, which is a situation that is not usually considered in marine fisheries management.

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If your local pond, lake, or watering hole is looking bright green this summer, chances are it has blue-green algae and it may be dangerous to you or your pets. A newly published study has used a novel approach to better understand why these algae form blooms and what makes them toxic.

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Today at the European Physical Society meeting in Stockholm, the international T2K collaboration announced definitive observation of muon neutrino to electron neutrino transformation. In 2011, the collaboration announced the first indication of this process, a new type of neutrino oscillation, then; now with 3.5 times more data this transformation is firmly established. The probability that random statistical fluctuations alone would produce the observed excess of electron neutrinos is less than one in a trillion. Equivalently the new results exclude such possibility at 7.5 sigma level of significance. This T2K observation is the first of its kind in that an explicit appearance of a unique flavor of neutrino at a detection point is unequivocally observed from a different flavor of neutrino at its production point.

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Rapid tooth replacement by sauropods, the largest dinosaurs in the fossil record, likely contributed to their evolutionary success, according to a research paper by Stony Brook University paleontologist Michael D’Emic, PhD, and colleagues. Published in PLOS ONE, the study also hypothesizes that differences in tooth replacement rates among the giant herbivores likely meant their diets varied, an important factor that allowed multiple species to share the same ecosystems for several million years.

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U.S. Department of State Sponsors Agreement for U.S.-China Collaboration to Create Alternative Energy Solutions

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Based on the analysis of 3-D landmark data from skull surfaces of Homo floresiensis, scientists provide compelling support for the hypothesis that Homo floresiensis was a distinct Homo species.

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Locally, changes in coastal ocean temperatures may be much more extreme than global averages imply. New research published in the June 18 edition of Public Library of Science (PLoS ONE) entitled “Decadal Changes in the World's Coastal Latitudinal Temperature Gradients,” is highlighting some of the distinct regional implications associated with global climate-change.

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Hauser will blog updates from Lindau, Germany June 30 – July 5.

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Presence of new ocean inlet in Great South Bay may help keep brown tide in check.

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A PET study led by a Stony Brook University Professor indicates that overeating and weight gain contributing to onset of diabetes could be related to a deficit in reward circuits in the brain.

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On June 7, an international team of scientists, artists and educators will launch an expedition to study the global marine debris crisis from one of the most breathtaking places on the planet: southwest Alaska. The Gyre project is a collaboration between the Anchorage Museum and Alaska SeaLife Center, in partnership with several national and Alaska-based organizations.

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In 2012, Nicholas Fisher a distinguished professor in the School of Marine and Atmospheric Sciences (SoMAS) at Stony Brook University and postdoctoral scholar Zosia Baumann, working with a colleague at Stanford University’s Hopkins Marine Station, reported that they had detected radioactivity in Pacific bluefin tuna swimming off the California coast. The source of the radioactivity was Japan’s Fukushima Dai-ichi powerplants, which were damaged by the strong earthquake and subsequent tsunami on 11 March 2011 and released large quantities of radioactivity into the Pacific Ocean. The news prompted widespread media interest and speculation as to the possible risks to seafood consumers posed by the levels of radioactivity found in the tuna.

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For Journalists only: To help kick off the voting on April 30, join Alan Alda in a Worldwide Assembly at noon EST to discuss the Flame Challenge finalists. Ten schools from around the world have been selected to talk live with Mr. Alda about this year's question, "What is time?"

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Increase in gold nanoparticles can accelerate aging and wrinkling, slow wound healing, cause onset of diabetes.

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Stony Brook alum and graduate student publish findings that identify surprising similarities between genetic and computer codes in the April 9 issue of PNAS.

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New York Mayor Bloomberg, New York State Energy Czar Kauffman, U.S. Acting Energy Undersecretary Sandalow, U.S. Undersecretary for Homeland Security Gerstein, Among Keynote Speakers.

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Stony Brook University received a total of $3 million in donations to enhance course offerings in Greek language and culture, with the immediate goal of creating curricula leading to a baccalaureate degree and graduate program. The gift, which includes $1.25 million gift from George Tsunis, $500,000 from members of the Long Island and New York Hellenic Community, and matching funds from the Simons Foundation, will establish the George and Olga Tsunis Center in Hellenic Studies and The James and Eleni Tsunis Chair in Hellenic Studies at Stony Brook University, in honor of Tsunis’ parents.

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Six months after Hurricane Sandy devastated the Eastern Seaboard and its energy grids, hundreds of the nation’s foremost experts from academia and industry, as well as a number of prominent elected officials and government policy makers, will convene for Advanced Energy 2013 April 30 to May 1 in New York City.

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State-of-the-art device to assist the elderly and disabled with sitting, standing and walking

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Contemporary scholarship has conceptualized modern fame as an open system in which people continually move in and out of celebrity status. However, according to new research, “Only 15 Minutes? The Social Stratification of Fame in Printed Media,” published in the April issue of the American Sociological Review, researchers led by Arnout van de Rijt, Assistant Professor of Sociology at Stony Brook University, reveal that most fame isn’t fleeting after all.

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The possible link between genetics and the development of autism will be the topic of the 17th Annual Swartz Foundation Mind/Brain Lecture at Stony Brook University on Monday, April 1, 2013 at 4:30 pm on the Main Stage of the Staller Center for the Arts. Guest lecturer Michael Wigler, Professor of Genetics at Cold Spring Harbor Laboratory and a trailblazer in the field of biomedical research, will present his findings on the connection.

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Award given to promising young faculty members in the beginning stages of their careers.

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The Research Your Future Career Symposium is sponsored by the American Society for Biochemistry and Molecular Biology (ASBMB) and is open to graduate students and postdocs at the participating institutions.

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Growing up in a poverty-stricken village in South Africa, Lesego Andrew Goba, 27, never imagined that his journey to the United States and eight years at Stony Brook University — which began in 2005 with an athletic scholarship — would be life-altering. A former Stony Brook Seawolves Men’s Basketball star, the 6-foot-9-inch, 245-pound Goba hopes to reach new heights, not on the basketball court but at Stony Brook University Hospital, where he recently secured a full-time nursing position in the Comprehensive Psychiatric Emergency Program (CPEP).

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Stony Brook University has long been known for providing opportunities for talented, high achieving students who want a quality, affordable, public higher education experience and the better future that goes with it. Now, a multitude of friends and former students have given to the University in historic fashion – helping to raise a staggering $200 million in 12 months.

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World-renowned primatologist Patricia Wright co-authors a study that will be published online in the February 28 issue of Behavioral Ecology.

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Stony Brook University’s 2013 "Stars of Stony Brook" Gala will honor one of its own this year, actor-director-writer-educator and six-time Emmy and Golden Globe Award winner Alan Alda, on Wednesday, April 24 at Pier Sixty at Chelsea Piers in New York City.

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A novel way to image the brain’s glymphatic pathway may provide the basis for a new strategy to evaluate Alzheimer's disease susceptibility, according to a research paper published in The Journal of Clinical Investigation.

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As the nations of the world prepare to vote on measures to restrict international trade in endangered sharks in early March, a team of researchers has found that one of these species – the oceanic whitetip shark – regularly crosses international boundaries.

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Scientists build new tree of life for placentals using ‘phylophenomics,’ visualize common ancestor.

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Poliomyelitis, in short polio, is a crippling, potentially fatal and highly contagious illness caused by poliovirus with no cure.

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Minerals found in the subsurface of Mars, a zone of more than three miles below ground, make for the strongest evidence yet that the red planet may have supported life, according to research “Groundwater activity on Mars and implications for a deep biosphere,” published in Nature Geoscience on January 20, 2013.

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The use of a new brain tumor-targeting contrast agent that differentiates between normal and cancer cells in conjunction with a high-powered microscopy system could potentially lead to a method of more precise neurosurgery for brain tumors, according to research paper published as a cover story in the December issue of Translational Oncology. Developed by researchers in the Department of Biomedical Engineering (BME) at Stony Brook University, the contrast agent adheres to a molecular marker of medulloblastoma, a form of brain cancer, and can be seen by the optical microscope system, also developed by the research team.

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An international team led by Xiang-Feng Zhou and Artem R. Oganov, PhD, theoretical crystallographers in the Department of Geosciences and Department of Physics and Astronomy at Stony Brook University, have established the structure of one of the most important high-energy-density materials, magnesium borohydride or Mg(BH4)2. Their findings, “First-Principles Determination of the Structure of Magnesium Borohydride,” have been published in the December 13 edition of Physical Review Letters.

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Assanis, Citovsky, Eanes, Ginzburg, Sprouse, Sternglanz, Kenneth Takeuchi, Jin Wang, Stanislaus Wong to be honored for contributions to science and engineering.

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Fifty years after scientists first posed a question about protein folding, the search for answers has led to the creation of a full-fledged field of research that led to major advances in supercomputers, new materials and drug discovery, and shaped our understanding of the basic processes of life, including so-called "protein-folding diseases" such as Alzheimer's, Parkinson's and type II diabetes.

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In the first-ever experiment of its kind, researchers have demonstrated that clean energy hydrogen can be produced from water splitting by using very small metal particles that are exposed to sunlight. In the article, “Outstanding activity of sub-nm Au clusters for photocatalytic hydrogen production,” published in the journal Applied Catalysis B: Environmental, Alexander Orlov, PhD, an Assistant Professor of Materials Science & Engineering at Stony Brook University, and his colleagues from Stony Brook and Brookhaven National Laboratory, found that the use of gold particles smaller than one nanometer resulted in greater hydrogen production than other co-catalysts tested.

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Stony Brook University unveiled its latest engineering feat, a 1.5 billion pixel Reality Deck, at a demonstration held at the University’s Center of Excellence in Wireless and Information Technology (CEWIT) on November 15. The Reality Deck, a 416 screen super-high resolution virtual reality four-walled surround-view theater, is the largest resolution immersive display ever built driven by a graphic supercomputer. Its purpose and primary design principle is to enable scientists, engineers and physicians to tackle modern-age problems that require the visualization of vast amounts of data.

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Harvester could save millions of dollars in energy costs while cutting CO2 emissions.

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Researchers and faculty will demonstrate, for the first time, the capabilities of Stony Brook’s newest engineering feat, a one-of-a-kind 416-screen immersive visualization facility that rivals the performance of modern supercomputers.

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Artem R. Oganov, PhD, finds novel compounds in search for the keys to the paradox of missing xenon in Earth’s atmosphere; findings may pave the way for new advances in the theory of chemical bonding.

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Newborn neurons in the adult hippocampus are critical for memory retrieval, according to a study by Stony Brook University researchers to be published in the November 11 advanced online edition of Nature Neuroscience.

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Most species loss in Bahamas and Greater Antilles explained by loss of land area.