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18-Oct-2010 3:15 PM EDT
Study Details Molecular Structure of Major Cell Signaling Pathway
University of North Carolina Health Care System

Scientists at the University of North Carolina at Chapel Hill School of Medicine have reported the exact molecular structure and mechanisms of a major cell signaling pathway that serves a broad range of functions in humans.

15-Oct-2010 8:50 AM EDT
Scientists find gene linked to alcoholism
University of North Carolina Health Care System

Researchers from the University of North Carolina at Chapel Hill School of Medicine have discovered a gene variant that may protect against alcoholism.

Released: 19-Oct-2010 10:15 AM EDT
UNC School of Medicine Establishes Two Regional Campuses
University of North Carolina Health Care System

The University of North Carolina at Chapel Hill School of Medicine today announced the expansion of its medical school to two regional campuses in Asheville and Charlotte, continuing to fulfill its mission to care for the people of North Carolina.

14-Oct-2010 11:05 AM EDT
Older Women with Normal T-Scores May Not Need Bone Mineral Density Screening for 10 Years
University of North Carolina Health Care System

A new study led by UNC's Dr. Margaret L. Gourlay finds that women aged 67 years and older with normal bone mineral density scores may not need screening again for 10 years. She presented these results on Sunday, Oct. 17, at the annual meeting of the American Society for Bone Mineral Research (ASBMR) in Toronto.

Released: 14-Oct-2010 1:05 PM EDT
Anti-Vomiting Drug Could Prevent Thousands of Hospitalizations, Save Millions of Dollars
University of North Carolina Health Care System

An economic analysis led by Canadian researchers, in collaboration with UNC's Michael J. Steiner, MD, concludes that routinely giving ondansetron to children with gastroenteritis-induced vomiting would prevent thousands of hospitalizations and save millions of dollars each year.

Released: 13-Oct-2010 11:15 AM EDT
N.C. Children’s Hospital Part of $12-Million Grant to Create First-of-its-kind Disease Registry for Inflammatory Bowel Disease
University of North Carolina Health Care System

North Carolina Children’s Hospital is one of 27 sites across the nation developing a disease registry for inflammatory bowel diseases (IBD). The research collaborative is part of a $12-million grant to Cincinnati Children’s Hospital Medical Center, enabling the creation of this first-of-its-kind registry system providing real time information on thousands of IBD cases across the country and, eventually, around the world.

6-Oct-2010 8:35 AM EDT
First Clinical Trial of Gene Therapy for Muscular Dystrophy Lends Insight Into the Disease
University of North Carolina Health Care System

A clinical trial designed to replace the genetic defect causing the most common form of muscular dystrophy has uncovered an unexpected aspect of the disease. The trial, based on therapy designed by scientists at the University of North Carolina at Chapel Hill School of Medicine, showed that some patients mount an immune response to the dystrophin protein even before they have received the gene therapy.

30-Sep-2010 11:00 AM EDT
No Sponge Left Behind
University of North Carolina Health Care System

A UNC study shows radio frequency tags may help prevent surgical sponges from being left in patients after operations.

Released: 4-Oct-2010 11:30 AM EDT
UNC Scientist Receives NIH Director’s New Innovator Award
University of North Carolina Health Care System

Ben Major, PhD, assistant professor of cell and developmental biology at the University of North Carolina at Chapel Hill, has been awarded one of 33 National Institutes of Health Director’s New Innovator Awards, one of the NIH’s most prestigious grants.

Released: 29-Sep-2010 3:00 PM EDT
UNC Awarded NIH Grant as Part of Nationwide Effort to Seek, Test, and Treat Inmates with HIV
University of North Carolina Health Care System

Investigators at the University of North Carolina at Chapel Hill comprise one of 12 scientific teams in more than a dozen states that will receive National Institutes of Health (NIH) grants to study effective ways to prevent and treat HIV/AIDS among people in the criminal justice system.

27-Sep-2010 3:00 PM EDT
Scientists Stack Up New Genes for Height
University of North Carolina Health Care System

An international team of researchers, including a number from the University of North Carolina at Chapel Hill schools of medicine and public health, have discovered hundreds of genes that influence human height. Their findings confirm that the combination of a large number of genes in any given individual, rather than a simple “tall” gene or “short” gene, helps to determine a person’s stature. It also points the way to future studies exploring how these genes combine into biological pathways to impact human growth.

Released: 29-Sep-2010 8:00 AM EDT
UNC Scientists Receive Grant to Develop Nanotechnology for Pancreatic Cancer Diagnosis and Treatment
University of North Carolina Health Care System

A team of UNC scientists has received a five-year $2,308,800 grant from the National Cancer Institute’s Cancer Nanotechnology Platform Partnerships to address the critical need for early diagnosis of and more effective treatments for pancreatic cancer.

Released: 27-Sep-2010 1:55 PM EDT
National Cancer Institute Awards $13.6 Million to UNC’s Carolina Center of Cancer Nanotechnology Excellence
University of North Carolina Health Care System

The National Cancer Institute has awarded a five-year, $13.6 million grant to the University of North Carolina at Chapel Hill’s Carolina Center of Cancer Nanotechnology Excellence (C-CCNE) based at the UNC Lineberger Comprehensive Cancer Center, for research to improve the diagnosis and treatment of cancer through applying/using advances in nanotechnology.

Released: 23-Sep-2010 2:00 PM EDT
UNC Bariatric Surgery Program Receives Two Important Distinctions
University of North Carolina Health Care System

The program has been accredited as a Level 1b facility by the Bariatric Surgery Center Network (BSCN) Accreditation Program of the American College of Surgeons (ACS). In addition, the program was named a Blue Distinction Center for Bariatric Surgery by Blue Cross Blue Shield of North Carolina.

20-Sep-2010 12:40 PM EDT
Researchers Identify Genetic Patterns That May Predict Severe Osteoarthritis
University of North Carolina Health Care System

The study, which was part of the Johnston County Osteoarthritis Project, showed patients with X-ray evidence of knee osteoarthritis who inherited a specific pattern of genetic variations in the interleukin-1 receptor antagonist (IL-1Ra) gene were almost twice as likely to progress to severe disease as other patients.

Released: 25-Aug-2010 10:15 AM EDT
UNC Hospitals receives performance achievement award from American College of Cardiology Foundation
University of North Carolina Health Care System

UNC Hospitals is one of only 26 hospitals nationwide to receive this award, which recognizes our commitment and success in implementing a higher standard of care for heart attack patients.

Released: 23-Aug-2010 9:00 AM EDT
Government Urges Universal Flu Vaccinations
University of North Carolina Health Care System

The flu kills more than 35,000 people in the United States in an average year—and most of those deaths could be prevented with a simple vaccine. After last year’s H1N1 outbreak, the government says everyone over the age of 6 months needs a flu shot this year.

16-Aug-2010 12:30 PM EDT
AIDS Virus Changes in Semen Make It Different than in Blood
University of North Carolina Health Care System

The virus that causes AIDS may undergo changes in the genital tract that make HIV-1 in semen different than what it is in the blood, according to a study led by researchers from the University of North Carolina at Chapel Hill.

Released: 19-Aug-2010 5:00 PM EDT
Genetics Underlie Formation of Body’s Back-Up Bypass Vessels
University of North Carolina Health Care System

Researchers at the University of North Carolina at Chapel Hill School of Medicine have uncovered the genetic architecture controlling the growth of the collateral circulation – the “back-up” blood vessels that can provide oxygen to starved tissues in the event of a heart attack or stroke.

17-Aug-2010 2:25 PM EDT
Consumers Need Protection from Unrealistic Claims of Home Genetic Tests
University of North Carolina Health Care System

In a perspective in the New England Journal of Medicine, UNC medical geneticist James P. Evans, MD, PhD and co-authors write that medical professionals “must ensure that rapidly evolving and multiplying genomic technologies are responsibly harnessed and that their promise is not oversold to the public.”

Released: 11-Aug-2010 9:05 AM EDT
Protecting Your Back, Neck and Arms from 'Laptop-itis'
University of North Carolina Health Care System

Purchasing a laptop computer has become a ritual for many new college students. But using a laptop often leads to posture problems, which can have serious long-term health consequences. UNC expert Dr. Kevin Carneiro explains how students can guard themselves from “laptop-itis” from orientation to final exams.

Released: 9-Aug-2010 9:10 AM EDT
Corporal Punishment of Children Remains Common Worldwide
University of North Carolina Health Care System

Three studies led by UNC researchers find that spanking and other forms of corporal punishment of children are still common in the U.S. and worldwide, despite bans in 24 countries.

Released: 4-Aug-2010 10:25 AM EDT
Eating-Disorders Expert: the 'Freshman 15' Is Only a 'Freshman Five'
University of North Carolina Health Care System

First-year college students are at risk for gaining weight and developing eating disorders. Two University of North Carolina Health Care experts weigh in on how to develop healthy eating habits on campus.

2-Aug-2010 9:15 AM EDT
Molecular Bandit Keeps Pain at Bay
University of North Carolina Health Care System

UNC researchers have identified an enzyme that blocks chronic pain by robbing a major pain pathway of a key ingredient. The enzyme could prevent lasting pain after surgery.

26-Jul-2010 4:00 PM EDT
Physician Authors Editorial on Cost-Effectiveness Study for Colon Cancer Screening
University of North Carolina Health Care System

Russell Harris, MD, MPH, professor of medicine at UNC and a member of UNC Lineberger Comprehensive Cancer Center, wrote an editorial in the Journal of the National Cancer Institute about a study concluding that CTC or “virtual” colonoscopy is not cost effective compared with colonoscopy if reimbursed at the same rate as colonoscopy.

Released: 23-Jul-2010 8:00 AM EDT
Study Questions Use of Paid Medical Expert Witnesses in Malpractice Cases
University of North Carolina Health Care System

This study suggests that the use of experts who are blinded to both the medical outcome and the litigation in malpractice cases may be a more objective way of determining whether or not the standard of care has been met.

16-Jul-2010 2:20 PM EDT
Unearthing King Tet: Key Protein Influences Stem Cell Fate
University of North Carolina Health Care System

UNC researchers reveal how a protein called Tet1 helps stem cells keep their “stemness” in a paper published in Nature.

13-Jul-2010 1:45 PM EDT
Scientists Author Editorial on International Trials for Vasculitis
University of North Carolina Health Care System

Two UNC School of Medicine faculty authored an editorial in the July 15, 2010 New England Journal of Medicine commenting on results from two clinical trials using the drug Rituximab to treat small-vessel vasculitis, a rare autoimmune disease.

Released: 14-Jul-2010 4:55 PM EDT
International AIDS Conference Features UNC Work
University of North Carolina Health Care System

New results and next steps are the focus of the year’s most important HIV/AIDS research gathering. UNC researchers present findings on antiretroviral drugs, prevention approaches and community interventions.

8-Jul-2010 4:30 PM EDT
Simple Tools Help Parents Understand a Child’s Risk of Obesity, Make Positive Changes
University of North Carolina Health Care System

According to a study performed in the North Carolina Children’s Hospital, researchers confirmed previous reports that parents of overweight or obese children do not recognize their child’s weight problem. But this time, by arming pediatricians with a “toolkit,” an easily used chart and a series of questions and suggestions, the researchers addressed several problems.

Released: 22-Jun-2010 8:00 AM EDT
Gut Bacteria Could be Key Indicator of Colon Cancer Risk
University of North Carolina Health Care System

A new study by researchers at the University of North Carolina at Chapel Hill School of Medicine suggests that a shift in the balance between the “good” bacteria and the “bad” bacteria that populate our gut could be a harbinger of colon cancer.

Released: 21-Jun-2010 10:30 AM EDT
Brain Signs of Schizophrenia Found in Babies
University of North Carolina Health Care System

UNC researchers are the first to identify brain abnormalities in children at high risk for schizophrenia shortly after birth. The finding could lead to earlier detection of schizophrenia and enable better prevention and treatment.

11-Jun-2010 12:05 PM EDT
Maternal, Infant Antiretrovirals Both Effective in Preventing HIV Transmission Through Breast Milk
University of North Carolina Health Care System

The largest study to date to examine methods to prevent HIV infection among breastfeeding infants concludes that giving antiretroviral drugs to HIV-infected breastfeeding mothers in sub-Saharan Africa or giving an HIV-fighting syrup to their babies are both effective.

11-Jun-2010 12:40 PM EDT
Study Helps Explain Why Black Patients with Lung Cancer Have Surgery Less Often than Whites
University of North Carolina Health Care System

A new study led by UNC researchers that looks at newly diagnosed lung cancer patients and follows them from diagnosis forward is one of the first to give reasons why patients don’t go to lung surgery and why surgery happens less often in blacks.

 
14-Jun-2010 3:15 PM EDT
Specific PTSD Symptoms Related to Anger and Aggressiveness Among Iraq/Afghanistan Veterans
University of North Carolina Health Care System

Focusing on certain PTSD symptoms may be key to treating anger among Iraq/Afghanistan veterans, according to a study led by University of North Carolina at Chapel Hill and Veterans Affairs researchers.

2-Jun-2010 1:35 PM EDT
Most Kidney Dialysis Patients Not Prepared for Emergency Evacuation
University of North Carolina Health Care System

A survey of kidney dialysis patients by University of North Carolina at Chapel Hill School of Medicine researchers finds that most have not taken the emergency preparedness measures that would enable them to survive a hurricane or any other disaster that disrupts power and water services.

Released: 3-Jun-2010 8:00 AM EDT
UNC and Olympus Partner to Open Advanced Imaging Center for Life Science Research
University of North Carolina Health Care System

The University of North Carolina (UNC) at Chapel Hill today opened the doors of a new facility designed to be one of the world’s most sophisticated research centers devoted to life science imaging. The new UNC-Olympus Research Imaging Center provides researchers with advanced microscopes and camera equipment, software, consultation and expertise, in an environment intended to encourage the highest levels of scientific inquiry. The center is designed to stimulate collaboration among top life science research faculty members and will be available to guest researchers as well.

Released: 12-May-2010 2:30 PM EDT
Bone Health for Men
University of North Carolina Health Care System

As men and women age into their 60s, 70s, AND 80s, their bodies gradually lose bone. This decrease in bone density puts both at risk for wrist, spine and hip fractures. While there are current bone density screening guidelines for women, guidelines do not exist for men. University of North Carolina School of Medicine bone researchers are working to change that.

Released: 12-May-2010 8:00 AM EDT
UNC's Patrick Sullivan Receives Grant for Genetics Study of Schizophrenia, Bipolar Disorder
University of North Carolina Health Care System

Patrick Sullivan, MD has received a 2010 Distinguished Investigator Award from NARSAD for a comparison of genetics in schizophrenia and bipolar disorder. His project is one of 15 selected out of 170 proposals submitted by researchers worldwide. Each project will each receive $100,000 annually in support of one year of research.

Released: 10-May-2010 7:00 PM EDT
UNC Researchers Receive $100,000 Grand Challenges Exploration Grant to Develop Male Contraceptive
University of North Carolina Health Care System

The grant will support an innovative global health research project conducted by James Tsuruta, PhD, and Paul Dayton, PhD, titled “Ultrasound as a long-term, reversible contraceptive.”

4-May-2010 12:45 PM EDT
China Needs Comprehensive Public Health Intervention to Control Syphilis Epidemic
University of North Carolina Health Care System

Despite the virtual elimination of syphilis in China in the 1950s, the sexually transmitted infection is currently at epidemic proportions in the country, and rates of infection will continue to grow unless a more comprehensive, coordinated effort of control is implemented, according to a perspective published in the May 6 issue of the New England Journal of Medicine.

Released: 5-May-2010 10:00 AM EDT
Losing, Then Finding Her Voice Becomes a Work of Art
University of North Carolina Health Care System

Margie Beth Labadie, an artist, adjunct assistant professor and coordinator of the Digital Academy at UNC-Pembroke, lost her speaking voice for several months because of a rare fungal infection but regained it after receiving treatment at the UNC Voice Center from Dr. Robert Buckmire and speech pathologist Ellen Markus.

29-Apr-2010 12:15 PM EDT
Mast Cell Tryptase Test May Aid in Diagnosis of Eosinophilic Esophagitis
University of North Carolina Health Care System

A pathology test may help doctors distinguish between two separate but overlapping esophageal disorders that require different courses of treatment, according to a study by researchers at the University of North Carolina at Chapel Hill.

29-Apr-2010 2:40 PM EDT
Brain Changes Associated with Fragile X Take Place Before Age Two
University of North Carolina Health Care System

Brain changes associated with the most common cause of mental retardation can be seen in magnetic resonance imaging (MRI) scans of children as young as one to three years old, according to a study by researchers at the University of North Carolina at Chapel Hill and Stanford University.

29-Apr-2010 11:00 AM EDT
Patients with IBS Commonly Use Narcotics
University of North Carolina Health Care System

The study found that 18 percent of IBS patients surveyed reported they were currently using narcotics. These patients reported more abdominal pain, poorer health quality, more IBS-related limitations, more hospitalizations and surgeries, and that they were more likely to use antidepressants and antacid medications.

29-Apr-2010 12:00 PM EDT
NAFLD Patients Have Increased Risk for Poor Outcomes After Liver Transplant
University of North Carolina Health Care System

Non-alcoholic fatty liver disease (NAFLD) is a bigger risk factor for liver transplant patients than obesity, high blood pressure and high cholesterol, according to a study by researchers at the University of North Carolina at Chapel Hill.

29-Apr-2010 4:00 PM EDT
Fasting May Not be Needed for Children’s Cholesterol Tests
University of North Carolina Health Care System

Physicians usually ask children to fast overnight before a cholesterol test. New research from the University of North Carolina at Chapel Hill School of Medicine shows that this may not always be necessary.

22-Apr-2010 1:50 PM EDT
Molecular Marker Could Help Spot Pancreatic Cancer Early
University of North Carolina Health Care System

Researchers at the University of North Carolina at Chapel Hill School of Medicine have identified a molecular marker of pancreatic cancer that may help spot the disease at its earliest stages, when it can be treated more successfully with surgery.

Released: 26-Apr-2010 10:25 AM EDT
Team Develops ‘Toolkit’ to Address Health Literacy Barriers
University of North Carolina Health Care System

The federal Agency for Healthcare Research and Quality (AHRQ) has released the “Health Literacy Universal Precautions Toolkit,” which was prepared for AHRQ by the University of North Carolina at Chapel Hill. The toolkit, which can be downloaded as a PDF from the AHRQ website, is designed to help primary care doctors and their staffs learn how to communicate more effectively with their patients.

24-Apr-2010 1:00 PM EDT
Researchers Find Genetic Variants Linked to Smoking Behaviors
University of North Carolina Health Care System

In a paper published in the journal Nature Genetics, a UNC team reported that three genetic regions were associated with the number of cigarettes smoked per day, one region was associated with smoking initiation and one variant was associated with smoking cessation.



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