Child abuse prevention experts from the University of North Carolina at Chapel Hill Injury Prevention Research Center and School of Medicine and Duke University Medical Center will undertake a $7 million statewide shaken baby prevention project.
People given a biological and genetics-based explanation for the causes of anorexia nervosa were less likely to blame people with anorexia for their illness than those given a sociocultural explanation, a University of North Carolina at Chapel Hill study found.
A hormone secreted by cells throughout the body and known to play a role in cardiovascular disease and other cell functions is also critical for proper formation of the lymphatic system in mice, according to research from the University of North Carolina at Chapel Hill School of Medicine.
A protein called CIB1 discovered by researchers at the University of North Carolina at Chapel Hill School of Medicine appears to play a major role in controlling new blood vessel growth, offering a target for drug treatments to help the body repair itself after injury and control unwanted blood vessel growth.
For patients with rheumatoid arthritis, combining one well-known, lower-cost synthetic drug with one of six biologic medications often works best to reduce joint swelling or tenderness, according to a new report by researchers at the RTI International-University of North Carolina at Chapel Hill Evidence-based Practice Center.
People older than 60 with high blood pressure are less likely than other groups of patients to receive advice from their doctors about lifestyle modifications that can help lower their blood pressure, a study by UNC researchers concludes.
Even though effective drug cocktails have improved the outlook for many patients with HIV, disease progression, including the time from AIDS onset to death, varies widely from patient to patient. Now, a study led by the University of North Carolina at Chapel Hill School of Medicine provides new evidence that psychological factors play a role in disease progression.
Scientists at the University of North Carolina at Chapel Hill have identified a gene crucial to the final step of the formation of a functional sperm cell.
In pregnant women at high risk for preterm birth, a single injection of corticosteroids has been shown to reduce the baby's chances of having serious lung problems after birth. A new study shows that repeat courses of corticosteroids are linked to an increased rate of cerebral palsy among children of these mothers.
Pregnancy may open a window of vulnerability for developing binge eating disorder, especially for women from lower socio-economic situations, according to a study from the University of North Carolina at Chapel Hill researchers and colleagues in Norway.
Scientists at the University of North Carolina at Chapel Hill School of Medicine have shown that a protein called neurexin is required for nerve cell connections to form and function correctly.
A study from the UNC Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill, the Vanderbilt-Ingram Comprehensive Cancer Center and the Sarah Canon Cancer Center in Nashville have identified an unusually high rate of allergic reaction in cancer patients living in the middle South who received a common drug used for treating their cancer.
Scientists at the University of North Carolina at Chapel Hill School of Medicine and Harvard Medical School have found that a mutated tumor suppressor gene, LKB1, may result in lung tumors that are more aggressive and more likely to spread throughout the body.
A collaborative study by scientists at the University of North Carolina at Chapel Hill and The Jackson Laboratory in Bar Harbor, Maine, has found that the genetic variation in the most widely used strains of laboratory mice is vastly greater than previously thought, their pedigrees not as previously assumed.
A specific genetic variation may be tied to an increased risk for severe premenstrual depression, scientists at the University of North Carolina at Chapel Hill and the National Institute of Mental Health have found.
The same genetic defect that causes a rare respiratory disease may also lead to some types of congenital heart disease, according to a study from the University of North Carolina at Chapel Hill School of Medicine.
Early life sun exposure, from birth to 20 years old, may specifically increase the risk of melanomas with BRAF gene mutations.
Taking folic acid supplements does not reduce the risk of developing precancerous tumors in the colon and may even increase the risk, a new study has found.
Scientists with the Lineberger Comprehensive Cancer Center at the University of North Carolina at Chapel Hill have for the first time implicated a growth-promoting cellular protein as one trigger of the inevitable recurrence of advanced prostate cancer in men who are undergoing drug treatment to shut down their sex hormones, or androgens.
A study led by scientists from the University of North Carolina at Chapel Hill may have identified a molecular mechanism involved in the development of schizophrenia.
Women with a recent diagnosis of cancer in one breast should have MRI screening of the opposite breast, concludes a multi-center study involving University of North Carolina at Chapel Hill researchers.
New research from the University of North Carolina at Chapel Hill School of Medicine has identified two proteins that may help protect against skin cancer.
Decreasing the rates of prostate cancer among black men may require improving access to routine health care, rather than increased education about the disease, a study from the University of North Carolina at Chapel Hill School of Medicine suggests.
Industry-funded studies of breast cancer therapies are more likely to report positive results than non-pharmaceutical funded studies, researchers from the University of North Carolina at Chapel Hill and the Dana Farber Cancer Institute have found. In addition, significant differences exist in the design and nature of clinical trials supported by the pharmaceutical industry compared to trials without industry involvement.
The regions of the brain that control vision and other sensory information grow dramatically in the first few months following birth, while the area that controls abstract thought experiences very little growth during the same period, University of North Carolina at Chapel Hill researchers have found.
The resurgence and spread in China of syphilis, an infection eliminated there from 1960 to 1980, represents a rapidly increasing epidemic calling for urgent intervention, according to authors of a new report documenting rising infection rates.
New laboratory research suggests that lithium and other drugs that inhibit a particular enzyme, GSK-3 beta, should be used with caution in treating Alzheimer's disease because too high a dose can impair, rather than enhance, neuronal function.
People with low levels of LDL cholesterol are more likely to have Parkinson's disease than people with high LDL levels, according to University of North Carolina at Chapel Hill researchers.
A gene discovered by researchers at the University of North Carolina at Chapel Hill School of Medicine has been associated with two forms of pancreatic cancer, according to a study by an international group of researchers.
Scientists now understand how an important protein converts chemical energy to mechanical force, thus powering the process of cell division, thanks to a new structural model by University of North Carolina at Chapel Hill researchers.
An international professional society has issued a patient's bill of rights for the treatment of eating disorders, conditions that affect an estimated 30 million Americans, most of them young women.
A new study has identified three subtypes of non-small-cell lung cancer tumors, a finding that may provide valuable clinical information about patient survival in early- or late-stage disease, how likely the cancer is to spread and whether the tumor will prove resistant to chemotherapy.
A protein known to play a role in blood clotting and other cell functions is also critical for proper sperm formation in mice, according to researchers from the University of North Carolina at Chapel Hill School of Medicine.
New research from the University of North Carolina at Chapel Hill ties low levels of a hormone secreted by the uterus and embryos to problems with pregnancy and fetal development. The findings also suggest that the hormone, adrenomedullin, plays a key role in maternal susceptibility to preeclampsia, a serious pregnancy complication that occurs in the third trimester.
Three separate studies confirm a gene that suppresses tumor cell growth also plays a key role in aging. Teams from the medical schools at the University of North Carolina at Chapel Hill, University of Michigan and Harvard University observed similar results in pancreatic islet cells and brain and blood stem cells.
Researchers at the University of North Carolina at Chapel Hill may have found a safer, more effective way to treat the life-threatening autoimmune skin disease pemphigus vulgaris without turning off the immune system.
An article reporting results from a pivotal clinical trial that helped gain U.S. Food and Drug Administration approval for the first treatment for Hunter disease has been published online by the journal Genetics in Medicine.
The cellular system that degrades faulty proteins created by the cystic fibrosis gene has been identified by University of North Carolina at Chapel Hill scientists. Turning off the degradation system allows some proteins to regain their proper shape, offering a new avenue for treatments aimed at curing the disease.
A new study from the University of North Carolina at Chapel Hill shows that different gene expression profiles that appear to be predictive for breast cancer outcomes agree, despite limited overlap in their gene lists.
Younger, premenopausal, African American women, when they get breast cancer, are more than twice as likely as older women, black or white, to get an aggressive breast cancer subtype, a study from the University of North Carolina at Chapel Hill has found.
African Americans, compared to Caucasians, have lower response rates to standard chemotherapy for advanced colon cancer but have significantly fewer severe side effects from the treatment. Genetic differences in metabolism may play a role.
Results of a multi-center clinical study of a drug currently approved for treatment of kidney cancer indicate that it may also be effective for people with recurrent and advanced lung cancer.
New research from the University of North Carolina at Chapel Hill has identified and established the substance in grapefruit juice that causes potentially dangerous interactions with certain medications.
Study shows that immunizing swine with a purified hemoglobin receptor protected the animals from a challenge infection, even after multiple attempts at infection.
For the second time in less than a year, University of North Carolina at Chapel Hill scientists have purified a novel protein and have shown it can alter gene activity by reversing a molecular modification previously thought permanent. Findings have implications for prostate cancer.
Two of four disinfectants recommended by the government for cleaning eye exam equipment are ineffective at inactivating adenovirus type 8, which is a common cause of epidemic keratoconjunctivitis (pink eye) outbreaks in eye clinics.
The first of several research studies in an international collaboration now is under way and is aimed at gaining new knowledge into the biology of HIV infection during its earliest days, before the immune system has produced antibodies to the virus.
The use of growth hormone therapy has been linked in some people to an increased risk of colon polyps. New research points to gene loss as possible factor.
Research describes how cells recover from heat, cold and other stressful conditions. The findings could have implications for the development of new therapies for cardiovascular and neurodegenerative diseases.
Taking aspirin to prevent coronary heart disease is beneficial and cost-effective for a wider range of men than is often recognized, a study from the University of North Carolina at Chapel Hill has found.
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