Three international teams of scientists, led by researchers at the University of California San Diego, University of Michigan and Stanford University, have published a trio of papers describing in unprecedented detail the structure and workings of G protein-coupled receptors (GPCRs), a large family of human proteins that are the target of one-third to one-half of modern drugs.
UC San Diego Health System is proud to receive the 2011 UHC Quality Leadership Award. This national award is given to academic medical centers that demonstrate excellence in delivering high-quality care as measured by the UHC Quality & Accountability Study, which has been conducted by the consortium annually since 2005.
For the first time ever, a surgical team led by Alan Hemming, MD, has successfully performed a domino transplant using a liver with a rare genetic disorder called methylmalonic acidemia (MMA).
Scientists at the University of California, San Diego School of Medicine have uncovered a previously unknown fail-safe (compensatory) pathway that potentially protects the brain and other organs from genetic and environmental threats. The discovery could provide new ways to diminish the negative consequences of genetic mutations and environmental toxins that cause neurological diseases and other maladies.
Over the last year, UC San Diego Health System managed to significantly decrease average door-to-balloon time, beating national guidelines by over a third, and improving care of patients with the most severe type of heart attack, known as STEMI (ST-segment-elevation myocardial infarction).
UC San Diego Health System has received the prestigious Stage 7 Award from HIMSS Analytics, a nationwide-system used to track electronic medical records (EMR) progress at hospitals and health systems. The hospital will be recognized at the annual HIMMS conference in February 2012 in Las Vegas.
In a paper published today in the journal Scientific Reports, a pair of researchers at the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences report that inhibiting the ability of immune cells to use fatty acids as fuel measurably slows disease progression in a mouse model of multiple sclerosis (MS).
A study by researchers at the Stein Institute for Research on Aging at the University of California, San Diego finds that successful aging and positive quality of life indicators correlate with sexual satisfaction in older women.
Patients in Nevada seeking care for liver disease may now access the university-level expertise of UC San Diego Health System’s Center for Hepatobiliary Disease and Abdominal Transplantation. Led by Robert Gish, MD, world-renowned hepatologist, patients may benefit by having access to a full spectrum of liver care, from diagnostics and testing to novel therapies and clinical trials not found anywhere else in the state.
Inflammatory bowel disease (IBD), which affects more than 1 million patients in North America, results from an uncontrolled immune response triggered by environmental factors, such as bacteria, in people genetically predisposed to the disorder. Researchers led by Jesús Rivera-Nieves, MD, of the Inflammatory Bowel Disease Center, Division of Gastroenterology at the UC San Diego School of Medicine, have discovered that expression of a newly identified human cytokine protects mice from colitis.
Hookah use among California youth ages 18 to 24 is rising rapidly according to a study conducted by researchers at University of California, San Diego School of Medicine. The study appears in the “First Look” online version of American Journal of Public Health.
For the first time in the western United States, a surgical team lead by Elisabeth McLemore, MD, has used a novel operating platform to perform the scarless removal of rectal tumors. Called Trans-Anal Minimally Invasive Surgery (TAMIS), the technique allows surgeons to excise large polyps and masses that cannot be completely removed during a routine colonoscopy.
UC San Diego Health System is one of only 167 hospitals nationwide to receive the American College of Cardiology Foundation’s NCDR ACTION Registry–GWTG (Get with the Guidelines) Gold Performance Achievement Award for 2011.
UC San Diego Health System has been recognized as having 83 Top Doctors in more than 30 specialties by U.S. News & World Report. Based on a peer nomination process, UC San Diego Health System’s results represent the majority of San Diego physicians recognized by their colleagues locally and nationally as being a top doctor and worthy referral.
UC San Diego Sulpizio Cardiovascular Center (SCVC) will officially open its doors to the public on Monday, August 8 after the California Department of Public Health (CDPH) certified the SCVC for patient care. The region’s first cardiovascular center is now accessible to the tens of thousands of Californians who are at risk for or suffer from heart disease and stroke.
In an innovative collaboration designed to speed the process of drug discovery, Pfizer, Inc. and the University of California, San Diego Health Sciences announced today that UC San Diego has joined the ranks of other top-tier life science research institutions across the country as part of Pfizer’s Centers for Therapeutic Innovation (CTI).
Researchers at the University of California, San Diego School of Medicine have shed new light on how surgery impacts both chronic kidney disease and bone health, particularly in women. For the first time, their findings point to the importance of pursuing kidney-sparing surgery in an effort to preserve kidney function and to reduce the risk of bone fractures later in life.
A study of data compiled by researchers in the Department of Pediatrics at the University of California, San Diego, appearing this week in the new journal, Childhood Obesity, showed that convenience resulted in lunchtime meals that accounted for between 36 and 51 percent of a child’s daily caloric needs. In addition, 35 to 39 percent of calories came from fat and the meals provided more than 50 percent of the recommended total daily sodium intake for most children– and as high as 100 percent of sodium levels recommended for pre-schoolers.
For the sixth consecutive year, UC San Diego Health System was named one of the nation’s “Most Wired” by Hospitals and Health Networks, a publication of the American Hospital Association.
A team of researchers from the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center will be participating in a cooperative agreement initiative, funded by the National Cancer Institute (NCI) of the National Institutes of Health, with four other major cancer centers.
A substantial number of people with eating disorders, such as anorexia nervosa have a chronic course. They are severely underweight and have a high likelihood of dying from malnutrition. No treatment has been found that helps people who are chronically ill. Now, a new study sheds light on the reason that some people have poor outcome.
Scientists at the University of California, San Diego School of Medicine have received a major 7-year, $18 million grant to begin translating emerging discoveries in the field of glycosciences into new discoveries and therapies related to heart, lung and blood diseases.
UC San Diego Health System ranks #1 among San Diego’s adult hospitals and among “America’s Best Hospitals” according to U.S. News & World Report’s “2011 - 2012 Best Hospitals” issue online today at www.usnews.com/besthospitals and available on newsstands August 30.
Multi-center study utilized a novel combined technique to treat cancer patients by bathing the brain in chemotherapy and relieving pressure from spinal fluid build-up (hydrocephalus).
In the first study to consider the impact of gender on patient outcomes in major gastrointestinal surgeries, researchers at UC San Diego Health System have found that women are more likely to survive after the procedure than men. The pattern is even more pronounced when comparing women before menopause with men of the same age.
In a novel imaging study of sleeping toddlers, scientists at the University of California, San Diego Autism Center of Excellence report that a diminished ability of a young brain’s hemispheres to “sync” with one another could be a powerful, new biological marker of autism, one that might enable an autism diagnosis at a very young age.
An international team of scientists led by researchers at the University of California, San Diego School of Medicine have used induced pluripotent stem cells (iPSCs) derived from patients with amyotrophic lateral sclerosis (ALS) to reveal for the first time how reduced levels of a specific protein may play a central role in causing at least one inherited form of the disease.
San Diego is one of the top 10 sunniest cities in the United States. Even when “June Gloom” clouds our skies, the sun is still very powerful. With that in mind, experts with UC San Diego Moores Cancer Center are helping raise awareness of the dangers of melanoma, the most serious type of skin cancer.
According to the California Teratogen Information Service (CTIS) Pregnancy Health Information Line, more studies are needed to evaluate men and the potential effect of illnesses, medications and lifestyle habits on fertility and pregnancy. For couples suffering fertility problems, the issue is linked to the potential father approximately 50 percent of the time. In close to a quarter of these cases, a specific cause is unknown.
Scientists at the University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have uncovered how the body’s immune system launches its survival response to the notorious and deadly bacterium anthrax. The findings, reported online today and published in the June 22 issue of the journal Immunity, describe key emergency signals the body sends out when challenged by a life-threatening infection.
How do you function when chronic pain is a part of your daily life? The UC San Diego Center for Mindfulness (UCSD CFM) at UC San Diego Health System offers a novel program to help people who are dealing with chronic pain “train their brains” to lessen their experience of discomfort and, in some cases, eliminate it.
As part of a multicenter clinical trial, surgical oncologists at UC San Diego Moores Cancer Center are comparing the effectiveness of standard chemotherapy to a tri-modality approach to halt advanced colon cancers.
Researchers at the University of California, San Diego, the Medical University of South Carolina and American Life Science Pharmaceuticals of San Diego have demonstrated that oral administration of a cysteine protease inhibitor, E64d, not only reduces the build-up of β-amyloid in the brains of animal models for Alzheimer’s disease, but also results in a substantial improvement in memory deficit.
Internationally-recognized cancer surgeon, Christopher Kane, MD, professor of surgery and chief, division of urology, has been named the inaugural holder of the C. Lowell and JoEllen Parsons Endowed Chair in Urology. The $2.5 million endowed faculty chair will enable Kane to recruit world-class talent and to support novel research and cancer treatment and prevention programs at UC San Diego Health System.
In space, the old movie slogan declares, “no one can hear you scream.” On the other hand, you might look like it, with puffy face, swollen eyes and distended neck veins. This is what happens when, screaming or not, bodily fluids shift in the absence of gravity. They surge inward and headward, elevating pressures inside the skull – and the risk of long-term vision impairment caused by engorged blood vessels impinging upon optic nerves.
While most people have a great deal of difficulty in dieting and losing weight, particularly if a diet extends over many months or years, individuals with anorexia nervosa can literally diet themselves to death. In fact, this disorder has a very high death rate from starvation. A new study, now online in the journal International Journal of Eating Disorders, sheds light on why these symptoms occur in anorexia nervosa.
While children of all ethnicities can contract Kawasaki disease, a study led by researchers at the Kawasaki Disease Research Center at the University of California, San Diego and Rady Children’s Hospital-San Diego finds that Filipino children with KD are at a higher risk for inflammation of the blood vessels of the heart than those of other Asian and non-Asian backgrounds.
A new study examining 18 years of data from the California state tobacco quitline found that African American smokers used the counseling service at significantly higher rates than Caucasian smokers. The finding is reported in the most recent issue of the American Journal of Health Promotion.
UCSD Experts: 80 Percent of women experience ‘baby blues’ shortly after giving birth.
An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, have developed a new method for discerning the functions of previously uncharacterized genes and placing them in interactive, functional networks that reveal how gene products interact to bring about cellular events.
A novel strategy developed by autism researchers at the University of California, San Diego School of Medicine, called “The One-Year Well-Baby Check Up Approach,” shows promise as a simple way for physicians to detect cases of Autism Syndrome Disorder (ASD), language or developmental delays in babies at an early age.
Tips and programs offered by UC San Diego Health System for families experiencing the neonatal intensive care unit (NICU) environment.
Researchers at the UCSD School of Medicine, the Gladstone Institutes in San Francisco and colleagues report a game-changing advance in stem cell science: the creation of long-term, self-renewing, primitive neural precursor cells from human embryonic stem cells (hESCs) that can be directed to become many types of neuron without increased risk of tumor formation.
Researchers at the University of California, San Diego School of Medicine, the National Institutes of Health (NIH) and the Mayo Clinic have published promising results of a clinical study using an experimental anti-fibrotic and anti-inflammatory drug called pirfenidone to treat patients with diabetic nephropathy.
The California Teratogen Information Service (CTIS) Pregnancy Health Information Line, a state-wide non-profit organization based at the University of California, San Diego with affiliates across North America, will join in the effort to raise awareness of meningitis prevention by helping to launch a new study that will assess safety of the meningitis vaccine in pregnancy.
Citing his on-going development of an immune-mediated gene therapy for intractable B cell leukemia, the Alliance for Cancer Gene Therapy (ACGT) has awarded Thomas J. Kipps, MD, PhD, professor of medicine in the University of California, San Diego School of Medicine and deputy director of research operations at the UC San Diego Moores Cancer Center, its 2010 Investigator Award in Clinical Translation of Cell and Gene Therapy.
Jean Yin Jen Wang, PhD, professor of medicine and biology in the University of California, San Diego School of Medicine, was elected today with 211 other distinguished scientists, scholars, writers, artists, business and civic leaders to the American Academy of Arts and Sciences.
Researchers at the University of California, San Diego School of Medicine say antibodies to a non-human sugar molecule commonly found in people may be useful as a future biomarker for predicting cancer risk, for diagnosing cancer cases early and, in sufficient concentration, used as a treatment for suppressing tumor growth.
The University of California, San Diego School of Medicine is among 27 research institutions selected across North America to be a part of the Cancer Immunotherapy Trials Network (CITN), funded by the National Cancer Institute (NCI). The CITN will establish a network of top academic immunologists to conduct multicenter research on agents that boost patients’ own immune systems to fight their cancer.
An electronic, cloud-based approach to sharing radiology files with other medical institutions is expediting the care of UC San Diego Health System trauma patients.
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