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Researchers at Mount Sinai School of Medicine in New York have found that sorafenib (Nexavar) helps patients with advanced liver cancer live about 44 percent longer compared with patients who did not receive the anti-cancer drug. The findings, published in the New England Journal of Medicine, is a significant advance in the management of liver cancer, which is the third cause of cancer death globally, often resulting in death within a year of diagnosis.

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Kevin G. Dunsky, MD, joins The Mount Sinai Medical Center as Director of Cardiovascular Institute Practice Development. He will also serve as the Associate Director of Quality Assurance for Mount Sinai Heart and Associate Professor of Medicine at Mount Sinai School of Medicine.

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Robert S. Klein, MD a HIV/AIDS expert has joined the faculty at Mount Sinai School of Medicine as Professor of Medicine and member of the Epidemiology, Biostatistics and Disease Prevention Institute. Dr. Klein will be Director of Clinical Research of Infectious Disease in the Division of Infectious Disease at Mount Sinai. He will develop his own research program while mentoring junior clinical investigators within the Division of Infectious Disease.

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The Mount Sinai Medical Center has opened the doors of its new Center for Advanced Medicine (CAM) at 5-17 East 102nd Street, between Madison and Fifth Avenues. The totally renovated 150,000 square foot building now houses ambulatory and neighborhood health care programs in one convenient location. It also provides enhanced quality of care through greater interaction between primary care physicians and specialists.

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Mount Sinai researchers have discovered that polyphenolics derived from red grape seeds may be useful agents to prevent or treat Alzheimer's disease (AD). The new study entitled, "Grape derived polyphenolics prevent Aβ oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease," was published in The Journal of Neuroscience. This new study explored the possibility of developing "˜wine mimetic pills' that would replace the recommended beneficial glass of red wine a day for AD prevention.

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Mount Sinai researchers may have unlocked the key to better understanding the effect addictive drugs have on the human brain. Researchers have just published the new breakthrough study, "Design Logic of a Cannabinoid Receptor Signaling Network that Triggers Neurite Outgrowth," in the latest issue of Science on May 16th, 2008.

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Mount Sinai School of Medicine researchers presented a new study to evaluate the impact of a tracking and feedback registry on breast cancer surgery patients. Presented at the American Association of Cancer Research Annual Meeting in San Diego, the study shows that a tracking system is key to improving rates of medical oncology consultation, reducing rates of adjuvant treatment underuse, and eliminating racial disparity in treatment.

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A new groundbreaking study published in Nature Medicine has implications for the future of transplantation and stem cell therapies as a treatment for Parkinson's disease. The study also provides a critical clue into the nature of Parkinson's disease itself. Researchers at Mount Sinai School of Medicine and Rush University Medical Center have discovered that dopamine cells that have been transplanted into the brain of patients with Parkinson disease develop pathologic changes characteristic of Parkinson's disease (Lewy bodies) and do not appear to function normally (reduced staining for dopamine transporter).

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A group of doctors and nurses from The Mount Sinai Medical Center recently traveled to Liberia to provide urgently needed medical care to the community. The team, led by Mount Sinai colorectal surgeon Jeffrey S. Freed, included sixteen physicians, seven medical students and three photographers who documented the trip.

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Mount Sinai researchers have identified a new receptor complex in the brain that responds to several types of antipsychotic drugs used to treat schizophrenia and also reacts to hallucinogenic drugs such as LSD.

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Mount Sinai researchers have discovered that the release of blood stem cells from bone marrow is regulated by the brain through the cyclical human biological clock, via adrenergic signals transmitted by the sympathetic nervous system. These new findings point out that the harvest of stem cells for transplantation may be improved by timing it at the peak of their release.

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Researchers in the Department of Medicine and Department of Neurosciences at Mount Sinai School of Medicine have discovered that chronic pain can be successfully treated with novel targeted gene therapy. In an effort to find a more effective treatment for chronic pain, researchers at Mount Sinai developed a gene therapy technique that simulates the pain-killing effect of opiate drugs. In the new study, researchers suggest that gene therapy for pain might in the future become a treatment alternative for patients with severe chronic pain.

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Two brothers from Savannah, Georgia diagnosed with prostate cancer surgery flew to The Mount Sinai Medical Center in New York to have lifesaving surgery on the same day this week. Dr. David B. Samadi, M.D., Chief of Robotics and Minimally Invasive Surgery in the Department of Urology at Mount Sinai successfully performed the robotic prostate cancer surgeries on the siblings one after another on Monday, January 14th, 2008.

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Mount Sinai Cardiac Experts Available for Heart Month Interviews

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A new study suggests that children who typically receive an operation to insert ear tubes because of ear infections or fluid in the ear may not need it, according to clinical practice guidelines.

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The National Football League and NFL Players Association's newly created NFL Player Joint Replacement Benefit Plan has selected The Mount Sinai Medical Center among only two hospitals in New York City and just fourteen across the entire country to assist eligible retired players in need of joint replacement surgery, it was announced today.

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Men experiencing erectile dysfunction, also known as ED, and urinary incontinence following treatment for prostate cancer, need not suffer alone and in silence. If oral medications fail, men and their partners need to know that there are other highly effective alternatives. That is the important message urologists on the staff of the Deane Prostate Health and Research Center, are hoping to communicate at a free community education seminar.

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"Put down cigarettes, pick up a hobby." "Exercise your brain, take a brisk walk." "Take control of your calories, eat less." These are a few of the new messages that will be popping up on lamp posts throughout the Upper East and West Sides and the Greater Harlem community of Manhattan as part of a new campaign"” Prescriptions for Healthy Living"” just launched by The Mount Sinai Medical Center.

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Full-time physicians spend an average of one full day a week providing services for patients that are not reimbursed by Medicare, according to a new study conducted by Jeffrey Farber, MD, Assistant Professor of Geriatrics at The Mount Sinai Medical Center, and published today in the journal Annals of Internal Medicine.

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Steven J. Burakoff, MD, one of the nation's leading cancer specialists, has been named Director of The Mount Sinai Medical Center's Cancer Institute, one of 12 new institutes focused on translational medicine. Dr. Burakoff's appointment will become effective on December 1.

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At The Society for Neuroscience annual meeting, Dr. Giulio Maria Pasinetti, M.D., Ph.D., Professor of Psychiatry and Neuroscience, Geriatrics and Adult Development and Director of the Center of Excellence for Research in Complementary and Alternative Medicine in Alzheimer's disease at Mount Sinai presented the following new breakthrough research findings for Alzheimer's disease and other brain disorders.

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A new study has identified commonly prescribed drugs for the treatment of hypertension may be capable of preventing Alzheimer's disease and cognitive deterioration.

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A Mount Sinai Medical Center study has found that lower frequency deep brain stimulation in young patients with primary torsion dystonia is as effective as higher frequency stimulation, which has been commonly used.

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The Mount Sinai Medical Center and New York City's Administration for Children's Services (ACS) have received a $2.4 million federal grant to establish the ACS-Mount Sinai Children's Trauma Institute.

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Mount Sinai School of Medicine has just received a major grant from the National Center for Complementary and Alternative Medicine (NCCAM), a component of the National Institutes of Health (NIH) and lead Federal agency for research on complementary and alternative medicine.

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Making statin treatment available without a prescription could help the fight against heart disease, says Valentin Fuster, MD, PhD, Director of Mount Sinai Heart and Director of the Zena and Michael A. Wiener Cardiovascular Institute and the Marie-Josée and Henry R. Kravis Center for Cardiovascular Health at The Mount Sinai Medical Center.

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Mount Sinai is pleased to announce that after a lengthy and thorough national search, Dr. Kishore Iyer and Dr. Juan del Rio Martin have been promoted to the Surgical Directors of Pediatric and Adult Liver Transplantation. Over the last 6 months, Dr. Iyer and Dr. del Rio Martin have shown the institution that they have the skills and temperament to lead these programs to even higher levels of achievement.

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How did a 250-year-old Jewish hospital located in the heart of Berlin, Germany, manage to survive during the Nazi regime? The answer to that question lies in a new traveling exhibit that is coming to The Mount Sinai Medical Center on October 1-19. To date, Mount Sinai is the only site in the United States to host this unique historical retrospective.

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The Mount Sinai Medical Center's Head and Neck Cancer Center is teaming up with ENT and Allergy Associates, LLP to help fight cancer. The clinical alliance between Mount Sinai and ENT and Allergy Associates, the largest ear, nose and throat, allergy and audiology practice in the tri-state area, together will provide patients with a full spectrum of high quality care, cancer screening and advanced surgical options for patients diagnosed with cancer and other serious ENT conditions.

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Researchers in the Department of Neuroscience at Mount Sinai School of Medicine have identified taste receptors in the human intestines. The taste receptor T1R3 and the taste G protein gustducin are critical to sweet taste in the tongue. Research now shows these two sweet-sensing proteins are also expressed in specialized taste cells of the gut where they sense glucose within the intestine.

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The Centers for Disease Control and Prevention (CDC) has designated the Mount Sinai School of Medicine in New York City as its newest Injury Control Research Center (ICRC). The new center will conduct research on persons with traumatic brain injuries in order to better understand the consequences of their injury and to help enhance the quality of their lives.

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A meta-analysis of four randomized Phase III placebo-controlled trials confirms that the injectable drug Efalizumab, a humanized therapeutic antibody designed to selectively and reversibly block the activation, reactivation and trafficking of T-cells that lead to the development of psoriasis, had an acceptable safety and efficacy profile in the treatment of psoriasis in heavy patients, researchers at Mount Sinai School of Medicine announced today.

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A 32-year-old mother of two small children, who was recently diagnosed with metastatic stomach cancer, underwent surgery using Hyperthermic Intraperitoneal Chemotherapy at The Mount Sinai Medical Center. The surgery, which took place on Thursday, July 26th is a breakthrough in cancer treatment at Mount Sinai, giving a heated form of chemotherapy to the patients during surgery directly into the abdomen while in the operating room.

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Cyclical, long-term estrogen injections protected brain cells from age-related deterioration, according to a new study conducted at Mount Sinai School of Medicine. The study suggests that age is a factor in estrogen treatment and sheds light on the intricate relationship between mind, age, and hormones.

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Results from an international multi-center Phase II clinical trial suggest that extracorporeal photopheresis (ECP) may be effective in treating patients with clinically active (OR symptomatic) Crohn's disease who cannot tolerate or are refractory to immunosuppressants and/or anti-TNF agents.

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The Mount Sinai Medical Center is the only hospital in New York City using the Novalis Shaped Beam Surgery System on spinal cancer. Novalis is the most advanced Stereotactic Radiosurgery(SRS) technology available to treat cancer tumors in the spine.

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Leading scientists from prestigious institutions around the world will convene in New York to report on the remarkable progress of their cancer research projects. Their findings will be highlighted at this press conference.

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The American Cancer Society and the National Palliative Care Research Center (NPCRC) are awarding $1.5 million in research grants to researchers at ten institutions for studies aimed at reducing suffering for seriously ill patients and their family caregivers. The studies will be conducted over the next two years.

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How your food is cooked may be as important to your health as the food itself. Researchers now know more about a new class of toxins that might soon become as important a risk factor for heart disease and metabolic disorders as trans fats.

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David B. Samadi, MD, one of the nation's leading urologic oncologists specializing in robotics and minimally invasive surgery for prostate cancer, has been named Chief of the Division of Robotics and Minimally Invasive Surgery in the Department of Urology at Mount Sinai.

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Mount Sinai School of Medicine has been named to the first-ever President's Higher Education Community Service Honor Roll, an honor that recognizes students, faculty, and staff for building a culture of service and civic engagement. Mount Sinai was one of ten schools around the country"”and the only medical school"”to be recognized as a Community Service Finalist for Excellence in General Community Service.

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A new imaging technology may hold the key to not only stopping heart attacks in their tracks but also preventing them for ever occurring. For the first time, researchers at Mount Sinai School of Medicine have shown the use multi-detector computed tomography (CT) imaging along with a novel contrast agent know as N1177 can detect dangerous, high-risk plaque which cause heart attack and stroke.

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Philanthropic gift brings Mount Sinai Medical Center to the forefront of personalized medicine, an emerging field using information about a person's genetic make-up to customize strategies for the detection, treatment, and prevention of disease, by establishing the Bronfman Institute for Personalized Medicine.

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A team lead by researchers at Mount Sinai School of Medicine, are the first to study outcomes in high cardiovascular risk patients with osteoarthritis. The researchers compared combination treatments of low-dose aspirin with the drugs ibuprofen, naproxen and the cox-2 inhibitor lumiracoxib. They have found that high cardiovascular risk patients taking ibuprofen and aspirin combined are nine times more likely suffer a heart attack.

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John H. Morrison, PhD, Dean of Basic Sciences and the Graduate School of Biological Sciences of the Mount Sinai School of Medicine, has received a MERIT Award) from the National Institute on Aging (NIA), a division of the National Institutes of Health (NIH). A MERIT (Method to Extend Research in Time) Award is grant support from the NIH that honors a longstanding and distinguished record in scientific research and achievement.

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The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today that Mount Sinai School of Medicine is a new Center of Excellence for Influenza Research and Surveillance. NIAID is awarding $23 million per year for seven years to establish six Centers of Excellence for Influenza Research and Surveillance around the country.

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Kenneth L. Davis, MD, President and Chief Executive Officer of The Mount Sinai Medical Center, today announced the appointment of Dennis S. Charney, M.D., Dean of Mount Sinai School of Medicine and Executive Vice President for Academic Affairs of The Mount Sinai Medical Center. Dr. Davis had served as Dean of the School since 2003.

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Mario Garcia, MD, a national expert in cardiac imaging, has been named Director of Non-Invasive Cardiology at Mount Sinai Heart.

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Dr. Martignetti receives award from Prostate Cancer Foundation for work focusing on therapeutic role of siRNA in metastatic prostate cancer.

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Researchers at Mount Sinai School of Medicine have just developed an advanced imaging technique to capture the movement of the microdomains of leukocytes or white blood cells.