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Released: 14-May-2020 6:25 PM EDT
Sculptor designs, builds ‘interactive contraptions’ from everyday materials to simulate human connections
University of Alabama at Birmingham

Even in isolation, Stacey Holloway can hold a hand, receive a swift kiss on the cheek or give a high-five. She can offer a nose rub, just like the ones she shares with her mother. She just does them all alone — that is, if you don’t count the kinetic, prosthetic models she created to help.

Released: 14-May-2020 4:45 PM EDT
Precision medicine guides choice of better drug therapy in severe heart disease
University of Alabama at Birmingham

Is personalized medicine cost-effective? Researchers have answered that question for one medical treatment, genotype-guided antiplatelet therapy for acute coronary syndrome patients with PCI. Their study uses pharmacogenomics and economic analysis of real-world clinical data.

Released: 14-May-2020 2:10 PM EDT
Surplus antioxidants are pathogenic for hearts and skeletal muscle
University of Alabama at Birmingham

Oxidative stress can be pathological. Now researchers report that the other end of the redox spectrum, reductive stress, is also pathological. Reductive stress causes pathological heart enlargement and diastolic dysfunction in a mouse model.

Released: 12-May-2020 6:50 AM EDT
Keeping your eyes healthy during the coronavirus pandemic
University of Alabama at Birmingham

Experts from UAB’s School of Optometry and UAB Callahan Eye Hospital and Clinics provide guidance for keeping your eyes safe during the coronavirus pandemic.

Released: 11-May-2020 3:45 PM EDT
How high school seniors can navigate uncertainty during the coronavirus pandemic
University of Alabama at Birmingham

Angela Stowe, Ph.D., has advice for students leaving high school, and those about to start college, on bringing closure to their K-12 experience and preparing to move forward with their lives.For high school seniors bound for college, the COVID-19 pandemic struck at a pivotal time in life — as they finish one chapter and prepare to start a new one.

Released: 8-May-2020 3:55 PM EDT
Individualized mosaics of microbial strains transfer from the maternal to the infant gut
University of Alabama at Birmingham

A microbiome “fingerprint” method shows that an individualized mosaic of microbial strains is transmitted to the infant gut microbiome from a mother giving vaginal birth. The study analyzed existing metagenomic databases of fecal samples from mother-infant pairs and used a germfree mouse model.

Released: 7-May-2020 2:25 PM EDT
Smartphone-based automated contact tracing: Is it possible to balance privacy, accuracy and security?
University of Alabama at Birmingham

UAB professor, Nitesh Saxena, Ph.D., explains the context of contact tracing and how it will help the impact of the novel coronavirus pandemic.

Released: 6-May-2020 11:55 AM EDT
Grant will fund pilot program to expand opioid use disorder treatment in Alabama
University of Alabama at Birmingham

UAB is launching a pilot program aimed at getting more opioid users into treatment, using telemedicine in three rural counties and emploing the Alabama One Health Record®, a statewide health information exchange, to track outcomes in these patients.

Released: 4-May-2020 4:55 PM EDT
UAB biotechnology aids hunt for novel COVID-19 DNA vaccine
University of Alabama at Birmingham

The Earle A. Chiles Research Institute is using the protein purification technology from TriAltus Bioscience to purify the spike protein of the COVID-19 virus. The protein will be used to measure the effectiveness of a new DNA vaccine, intended to evoke an immune response against the spike protein.

Released: 1-May-2020 4:25 PM EDT
Gender identity plays a role in the amount of pain experienced by individuals with chronic pain
University of Alabama at Birmingham

Gender identity and genetic sex are distinctly variable when it comes to pain tolerance, according to a study published in the Journal of Pain Research.

Released: 30-Apr-2020 1:05 PM EDT
In one of America’s rare undergraduate immunology programs, students are ‘preparing for the next pandemic’
University of Alabama at Birmingham

UAB's Undergraduate Immunology Program, one of a handful of immunology majors available in the United States, gives students real lab experience with more than 100 faculty pursuing cutting-edge research.The entire planet, more or less, is fixated on the greatest pandemic in modern memory. Claire Elliott is already preparing for the next one.

   
Released: 27-Apr-2020 4:15 PM EDT
Coronavirus may damage kidneys, impact dialysis supplies
University of Alabama at Birmingham

. Ashita Tolwani, a nephrologist at the University of Alabama at Birmingham, explains how COVID-19 is impacting patients and putting a strain on the availability of dialysis supplies..

Released: 24-Apr-2020 12:05 PM EDT
Working behind the scenes: UAB pathologists play key role in fighting coronavirus pandemic
University of Alabama at Birmingham

Testing has been a major cause for concern worldwide ever since the pandemic began, but clinicians and researchers with UAB’s Department of Pathology have been working around the clock to make testing available for as many people as possible, making sure accurate results are available in a timely manner.

Released: 23-Apr-2020 3:05 PM EDT
Search for drugs effective against COVID-19 includes UAB and Southern Research
University of Alabama at Birmingham

The University of Alabama at Birmingham will join an international effort coordinated by Scripps Research to test drugs for COVID-19. The work centers around ReFRAME, a vast collection of drugs developed for other diseases that are already known to be safe for humans.

Released: 17-Apr-2020 11:35 AM EDT
In one of America’s rare undergraduate immunology programs, students are ‘preparing for the next pandemic’
University of Alabama at Birmingham

There are only a handful of immunology majors offered at U.S. universities. A report last October by UAB researchers made the case for expanding these programs. Now faculty and students are seeing an explosion of interest.

   
Released: 15-Apr-2020 3:55 PM EDT
New boron material of high hardness created by plasma chemical vapor deposition
University of Alabama at Birmingham

Researchers used microwave-plasma chemical vapor deposition to create thin crystal films of a novel boron-rich boron-carbide material that has 37 percent the hardness of cubic diamond and acts as an insulator. The new material’s properties were predicted from first-principles analysis.

Released: 14-Apr-2020 4:00 PM EDT
Making the Most of Your Groceries During the Coronavirus Pandemic
University of Alabama at Birmingham

Tara Harman, RDN, has tips on how to stretch your groceries while saving money.

Released: 7-Apr-2020 4:10 PM EDT
UAB among first in the U.S. to offer clinical trial for the treatment of patients with severe COVID-19 using nitric oxide
University of Alabama at Birmingham

iNO has been used for the treatment of failing lungs, but it was also found to have antiviral properties against coronaviruses.The University of Alabama at Birmingham has been selected to begin enrolling patients in an international study assessing the use of inhaled nitric oxide (iNO) to improve outcomes for COVID-19 patients with severely damaged lungs.

Released: 3-Apr-2020 3:20 PM EDT
A direct protein-to-protein binding couples cell survival to cell proliferation
University of Alabama at Birmingham

The regulators of apoptosis watch over cell replication and the decision to enter the cell cycle. Researchers now show a direct link between the protein MCL1 — a member of the BCL2 protein family known as the gatekeepers of apoptosis — and the cell-cycle checkpoint protein P18.

Released: 30-Mar-2020 9:00 AM EDT
UAB will test a COVID-19 vaccine candidate created by Altimmune Inc.
University of Alabama at Birmingham

The University of Alabama at Birmingham is launching a collaboration with the biopharmaceutical company Altimmune, Inc. for preclinical testing of a potential vaccine to prevent COVID-19 disease



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