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The ideal treatment for any autoimmune disease such as multiple sclerosis (MS) would preserve the immune system’s ability to protect the body. In July, a team of researchers published a study in The Journal of Neuroinflammation reporting progress toward this goal. After ‘knocking out’ a transcription factor called Oct1, investigators saw a significant reduction in symptoms in mice with MS-like disease. More importantly, the mice preserved most of their ability to clear viral infections.

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Today, Sigma Chi International Fraternity announced a new $20-million pledge to Huntsman Cancer Foundation (HCF), dedicated to and used for women’s cancer research, treatment and wellness at Huntsman Cancer Institute (HCI). The announcement came during the fraternity’s biennial Grand Chapter conference in Salt Lake City. This pledge follows an $11 million pledge made in 2015, the largest to date in the history of men’s fraternities.

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Researchers at University of Utah Health explored the long-term psychological impact of food restrictions on normal eating patterns in patients.

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University of Utah Health researchers explored the need for continued substance abuse counseling and access to naloxone prescriptions and mental health care in the year following childbirth.

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Researchers explore familial relationships using unique Utah resources to develop high-risk profiles with the hope of identifying those at greater risk for atrial fibrillation.

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In the face of escalating teen suicides, Utah launched an app. No one knew just how much change it would bring.

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Using cryo-EM, researchers capture how Cdc48, harvested directly from yeast cells, unfolds proteins.

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Research findings opens opportunities to offer opportunities to develop new treatments to tackle metabolic diseases, like diabetes.

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A new study links the benefits of comprehensive oral care to the physical and emotional recovery of patients seeking treatment for substance use disorder.

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An app that allows parents and doctors to monitor a child’s asthma has a big impact on managing the disease. When families monitored symptoms with eAsthma Tracker and adjusted care accordingly, children had better asthma control and made fewer visits to the emergency department. Using the app also meant that children missed fewer days of school and parents took fewer days off work, improving quality of life.

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Postpartum women who have previously or currently struggle with substance abuse are at greater risk of overdosing.

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The results of a joint study between University of Utah Health and Intermountain Healthcare show inducing labor one week early costs the same as waiting for spontaneous labor.

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By the time Tyler turned 10, he lost his ability to walk, see, and hear, but the cause remained a mystery. His family eventually turned to University of Utah Health, where scientists searched Tyler’s DNA for clues to his condition. What they discovered led to a life-changing treatment.

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Researchers at University of Utah Health found pairing music with one of four pain medications offered a promising complementary strategy to treat pain.

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When treating patients, doctors sometimes overlook how their decisions impact a world they never see: a patient’s home life. In the case of some serious infections in children, oral antimicrobial drugs are just as good at treating these ailments at home as the standard, intravenous medications. But according to new research led by investigators at University of Utah Health, by-mouth medications excel in the important measure of preserving parents’ quality of life.

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Researchers at University of Utah Health have developed a new approach that targets the misfunctioning immune cells while leaving normal immune cells in place.

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A multi-institutional, international team of researchers has developed a method that identifies individuals recently infected with Vibrio cholerae O1. The results of the study are available online in the February 20 issue of the journal Science Translational Medicine.

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Researchers at University of Utah Health detailed the function of cone snail insulins, bringing them one step closer to developing a faster-acting insulin to treat diabetes.

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Researchers at University of Utah Health and University of Washington found an FDA-approved cancer drug--paclitaxel--offers protection to mice after experiencing mild traumatic brain injuries.

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Researchers at the University of Utah Health conducted the first population-based study of suicidality in individuals with ASD in the United States. The 20-year retrospective study found that for individuals with autism, particularly females, the risk of suicide has increased through time compared to their non-autistic peers.

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Researchers at University of Utah Health conducted a state-by-state analysis to understand the geographic disparities for patients diagnosed with melanoma. The results of their study suggest that lower survival is associated with more practicing physicians in a region and higher population of Caucasians.

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Researchers identified three new sites in the genome that appear to be associated with Polycystic Ovary Syndrome.

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Researchers use a data set of more than 100,000 individuals to identify genetic regions intolerant to change that may underlie developmental disorders.

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Air quality has been associated with numerous adverse health outcomes from asthma to pre-term birth. Researchers at University of Utah Health found women living along the Wasatch Front — the most populous region in the state of Utah — had a higher risk (16 percent) of miscarriage following short-term exposure to elevated air pollution.

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Up to 80 percent of those surveyed have lied to their doctor about information that could impact their health, including accurately describing their diet and how often they exercised. When survey participants explained their reasoning for doing so, they said that they wanted to avoid being judged and didn’t want to be lectured about how bad certain behaviors were. The research was led by scientists at University of Utah Health and Middlesex Community College.

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Suicide is the 10th leading cause of death in the United States, claiming more than 44,000 people in the country every year, similar to the number of deaths caused by the opioid epidemic. Previous studies show that suicide tracks in families independent of the effects from a shared environment. Researchers at the University of Utah Health are using resources unique to the state to identify underlying genetic factors that may increase the risk for suicide.

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In 2017, the American College of Cardiology and the American Heart Association released new blood pressure guidelines, lowering hypertension threshold to 130/80 mm Hg from the previous 140/90 mm Hg. A new study predicts that achieving and maintaining the 2017 guideline blood pressure goals could prevent more than 3 million cardiovascular disease events over ten years.

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For decades, scientists have examined how regions of the brain communicate to understand autism. Researchers at University of Utah Health believe the symptoms of autism may result from sustained connections between regions of the brain.

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Gone are the days of heavy science textbooks with over-used examples and hard-to-grasp lessons. The Genetic Science Learning Center (GSLC) at the University of Utah is bringing science education into the 21st century with an online, interactive and multimedia curriculum that teaches up-to-date concepts in evolution and genetics to high school students.

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Researchers at University of Utah Health found that ADHD patients had an increased risk of developing Parkinson’s and Parkinson-like diseases than individuals with no ADHD history.

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Researchers at University of Utah Health examined the diabetes community’s online Twitter conversation to understand their thoughts concerning open source artificial pancreas (OpenAPS) technology.

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Scientists at University of Utah Health report for the first time that a protein, called Staufen1, accumulates in cells of patients suffering from degenerative ataxia or amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.

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Researchers at University of Utah Health have developed high-tech tools to uncover the genetic cause of the most difficult to diagnose cases.

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Inducing labor in healthy women at 39 weeks into their pregnancy reduces the need for cesarean section and is at least as safe for mother and baby as waiting for spontaneous labor. Choosing to induce could also reduce the risk that mothers will develop preeclampsia and that newborns will need respiratory support after delivery, according to a study publishing in the New England Journal of Medicine on August 8.

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Researchers at University of Utah Health developed a proof-of-concept technology using nanoparticles that could offer a new approach for oral medications.

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By analyzing thousands of flies, scientists at University of Utah Health found that variation in a background gene, called Baldspot, can make a difference in severity of the disease.

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The Second Annual University of Utah Translational Hypertension Symposium assembles national experts in hypertension treatment and research. This year's meeting will focus on implementation strategies for the 2017 American College of Cardiology/American Heart Association guidelines, the future of hypertension research, and a mentored workshop for early-stage investigators.

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During 325 observations, researchers at the University of Utah and University of Michigan identified 283 protocol violations, which could increase the risk of self-contamination of health care personnel and transmission of antibiotic-resistant organisms to patients.

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The researchers examined 17 years of transplantation records and found no significant change in the recipients’ chance of survival when the organ donation came from victims of drug intoxication. The study publishes online on May 17 in the New England Journal of Medicine.

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Researchers at the University of Utah Health are looking to the salience network of the brain to develop music-based treatments to help alleviate anxiety in patients with dementia. Their research will appear in the April online issue of The Journal of Prevention of Alzheimer's Disease.

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An interdisciplinary team of scientists at University of Utah Health are using animals' unique traits to pinpoint regions of the human genome that might affect health. The results of this project are available in the March 6 issue of the journal Cell Reports.