This story starts with a young graduate student in San Diego and leads all the way to Sierra Leone, to a unique hospital where Lassa fever victims arrive by the thousands every year.
Assistant Professor Seth Tomchik of the Florida campus of The Scripps Research Institute (TSRI) has received $2 million in funding from the National Institutes of Health’s National Institute of Neurological Disorders and Stroke (NINDS). The new five-year grant funding will support the study of neurofibromatosis type I, an inherited disorder that results from genetic mutations affecting a protein called neurofibromin (Nf1).
The Scripps Research Institute (TSRI), one of the world's largest, private, non-profit research organizations, today announced the appointment of Joel S. Marcus to its Board of Directors.
Scientists at The Scripps Research Institute (TSRI) have given new superpowers to a lifesaving antibiotic called vancomycin, an advance that could eliminate the threat of antibiotic-resistant infections for years to come.
With mosquito season looming in the Northern Hemisphere, doctors and researchers are poised to take on a new round of Zika virus infections. Now a new study by a large group of international researchers led by scientists at The Scripps Research Institute (TSRI) explains how Zika virus entered the United States via Florida in 2016—and how it might re-enter the country this year.
Clostridium botulinum is the bacterium that causes the neurointoxication, which produces one of the most potent toxins on earth and is classified as a potential bioterrorism threat. While no cure exists—and botulism treatment options are limited—a serendipitous discovery by scientists at The Scripps Research Institute (TSRI) may provide a new therapy that can stop the neurotoxin even in its more severe, advanced stages of action.
In their quest to replicate themselves, viruses have gotten awfully good at tricking human cells into pumping out viral proteins. That’s why scientists have been working to use viruses as forces for good: to deliver useful genes to human cells and help patients who lack important proteins or enzymes.
A team of researchers led by Associate Professor Vijay Reddy at The Scripps Research Institute (TSRI) has now uncovered the structural details that make one virus a better tool for future therapies than its closely related “cousin.”
Three chemists from The Scripps Research Institute (TSRI)—Dale Boger, Jin-Quan Yu and Phil Baran—have received awards from the Royal Society of Chemistry (RSC), a renowned professional organization for chemists based in the United Kingdom, with more than 54,000 members worldwide.
Despite intense research, there’s been much confusion regarding the exact role of a protein in a critical cancer-linked pathway. On one hand, the protein is described as a cell proliferation inhibitor, on the other, a cell proliferation activator, a duality that has caused a great deal of scientific head scratching. Now scientists from the Florida campus of The Scripps Research Institute (TSRI) have solved the conundrum, uncovering the regulatory machinery underlying the function of a protein, called angiomotin.
Scientists at The Scripps Research Institute (TSRI) in La Jolla have revealed new clues to the wiring of the brain. A team led by Associate Professor Anton Maximov found that neurons in brain regions that store memory can form networks in the absence of synaptic activity.
Chemists at The Scripps Research Institute (TSRI) have discovered a new method that greatly simplifies, and in many cases enables for the first time, the making of a vast range of organic molecules.
Chemists at The Scripps Research Institute (TSRI) have developed a broad and strikingly easy method for synthesizing a class of molecules that have demonstrated value as pharmaceuticals.
A new study led by scientists at The Scripps Research Institute (TSRI) could help researchers develop personalized treatments for alcoholism and alcohol use disorder.
Professor Michael Farzan, co-chair of the Department of Immunology and Microbiology on the Florida campus of The Scripps Research Institute (TSRI) has received $4.8 million in funding through a 2017 Avant-Garde Award for HIV/AIDS research from the National Institutes of Health’s National Institute on Drug Abuse (NIDA). The new funding will support a five-year project, led by Farzan, to bring a potential HIV vaccine closer to human clinical trials.
Scientists at The Scripps Research Institute (TSRI) have found a way to tether HIV-fighting antibodies to immune cells, creating a cell population resistant to the virus.
The Scripps Research Institute (TSRI), one of the world's largest, private, non-profit research organizations, today announced the appointment of Ronald W. Burkle to its Board of Directors—adding another world-renowned business leader and philanthropist to its newly restructured board.