Results of an eight-year national clinical trial show that combining chemotherapy and radiation treatment at the same time offers patients with advanced cancer of the larynx, or voice box, better hope of preserving their voice.
Johns Hopkins today announced the introduction of the Palm OS(tm) version of its digital Guide to Antibiotics and Infectious Disease -- the ABX Guide -- designed to give physicians free and up-to-the-minute information on antibiotics and their proper use. The ABX Guide offers information on more than 190 drugs and more than 140 diseases treated by both specialists and primary care physicians.
David Satcher, M.D., Ph.D., United States Surgeon General, is the commencement speaker for Johns Hopkins University School of Medicine May 24, 2001.
Research initiated by Johns Hopkins has found that a mouse bone marrow stem cell is capable of developing into the specialized cells lining intestines, lung and skin. This study provides some of the first clear evidence that a transplanted bone marrow stem cell can not only reconstitute bone marrow, but also may play a role in healing these other tissues and organs as well.
News Tips from Hopkins at the APS-SPR 2001 Conference April 27 - May 1, Baltimore Convention Center
The following news tips are based on upcoming presentations at two pediatric medical meetings in Baltimore.
A team of researchers from the Johns Hopkins Children's Center and four other medical centers have found that the antidepressant drug fluvoxamine significantly lowers anxiety without major side effects in most children who take it.
John Phillips Dorst, M.D. director of pediatric radiology at Johns Hopkins for more than two decades, died of complications from a brain tumor on April 17 at Brightwood Genesis Eldercare in Lutherville, Md.
After a half-century of looking at everything from Accutane to zinc, dermatologists still can't prove which acne treatments and drugs work best, a team at Johns Hopkins Children's Center finds after combing the scientific literature.
Unexplained weight loss, exhaustion, a weak grip, slow walking speed and low energy -- the hallmarks of frailty -- are most likely to strike women, African Americans, the less educated and the poor, according to a nationwide study of more than 5,000 older adults.
A research team led by a Johns Hopkins Children's Center scientist has found the strongest evidence yet that a virus may contribute to some cases of schizophrenia.
Winners of the Johns Hopkins Young Investigators' awards cite different reasons for becoming scientists, but have in common a knack for elegant research, a keen discipline to see it through and an unusual ability to communicate what they're doing.
Johns Hopkins today launched a rigorously peer-reviewed database and a point of care decision-support system designed to give office and hospital-based physicians free and up-to-the-minute information on antibiotics and their proper use.
Daniel N. Sauder, M.D., an internationally acclaimed dermatologist, has been appointed the new director of dermatology at Johns Hopkins, effective July 1. Sauder succeeds dermatologist Grant Anhalt, M.D., who served as interim director.
Researchers at Johns Hopkins announce that a novel method of modifying an allergen, such as ragweed, by attaching a synthetic piece of DNA to it, is showing promise in initial clinical trials. The finding may lead to a more effective vaccine for treating allergic diseases such as hay-fever or asthma.
John Hopkins researchers have developed the first color-coded tracking system to see how receptors on the surface of a living cell transmit signals to the cell's interior and regulate a wide range of biological processes. The technology should significantly speed up the search for drugs needed to treat heart disease, cancer, asthma and other ailments. (Science, 3-23-01)
Scientists discovered the gene for Huntington's disease in 1993, but in all that time, they couldn't explain how the gene leads to the death of a small patch of nerve cells in a key part of the brain. (Science, 3-01)
American hospitals with a shortage of "intensivists" to treat patients in their intensive care units could benefit from having such experts monitor their patients offsite via computer, Johns Hopkins researchers have found. (Critical Care Medicine)
A new Johns Hopkins Children's Center study reveals that caring for a chronically ill child can be a positive experience for many mothers and families. (Ambulatory Pediatrics, 3-01)
The following news tips from Johns Hopkins are based on abstracts or posters to be presented at the American College of Cardiology's 50th Scientific Sessions, held March 18-21 in Orlando, Fla.
Johns Hopkins researchers report that a portable device that's "a cross between a pager and your own mother" can, within half a year, lead to a significant drop in the amount of virus HIV patients carry in their blood or spinal fluid.
Scientists at Johns Hopkins and Tsukuba University in Japan have confirmed the existence of a long-suspected natural system the body uses to block the cancer-causing effects of toxic chemicals in food and the environment. (PNAS)
A new study by Johns Hopkins Children's Center neurologists suggests that baclofen, a drug long thought to be effective in reducing the vocal and motor tics associated with Tourette syndrome, improves a patient's overall sense of well-being but does not significantly reduce tics. (Neurology, 3-01)
A Johns Hopkins neurologist, inspired by the plight of a young patient, has established a nationwide consortium of Centers of Excellence for research and treatment of the often-paralytic neurological disease transverse myelitis (TM).
Researchers have developed the first genetic profile for Crohn's disease and ulcerative colitis, two types of inflammatory bowel diseases. (Human Molecular Genetics, 3-01)
Even though aspirin's pain-killing capacity was well known to Hippocrates in the fifth century B.C., exactly what it does remains somewhat of a mystery. Now, Johns Hopkins researchers have shown that aspirin inhibits interleukin-4, a protein involved in allergic reactions and inflammation. (Blood, 3-01)
Pediatric kidney specialists are 60 percent more likely than their peers who treat adults to recommend peritoneal dialysis over hemodialysis, report Johns Hopkins Children's Center researchers. (JAMA, 2-01)
Scientists at Johns Hopkins have shown that a specific enzyme in the brain is essential for nerve cells to form a hallmark of Alzheimer's disease -- the so-called amyloid plaques that collect and surround brain cells. (Nature Neuroscience, 3-01)
Researchers at the Johns Hopkins Children's Center and Children's Hospital Medical Center of Cincinnati have discovered a genetic defect associated with lung disease in infants and adults. (NEJM, 2-01)
Drinking alcohol and bicycling don't mix well, say Johns Hopkins researchers, whose study of 466 Maryland bicyclists found that a third of fatally injured riders had elevated blood alcohol levels at the time of their accident. (JAMA, 2-21-01)
Working with Baltimore churches, homeless shelters and food kitchens, Johns Hopkins researchers have proven that community-based testing programs are powerfully effective in reaching people at high risk for HIV. Their report was prepared for this week's 8th Annual Conference on Retroviruses and Opportunistic Infections.
People who live in fear of their peanut allergy, anxiously avoiding numerous products and worrying that accidental exposure could cause a severe or even fatal reaction, may be cheered to learn that they may outgrow it, according to a study by Johns Hopkins researchers. (J. of Allergy and Clinical Immunology, 2-01)
The Johns Hopkins team that first unearthed two chromosomes as the site of genes for asthma and allergic disease has moved closer to identifying those genes with the help of a unique Barbados island population. (Genomics)
A lab test for the human papilloma virus (HPV) combined with a visual inspection of the cervix could identify pre-cancerous lesions and vastly reduce the number of false positives among women at high risk for cervical cancer in developing countries. (International Journal of Gynecology & Obstetrics, 1-01)
With a $58.5 million gift from an anonymous donor, The Johns Hopkins University School of Medicine is launching an Institute for Cell Engineering, fostering research that not long ago would have been marked as science fiction.
President Clinton has appointed Johns Hopkins Children's Center psychiatrist James Harris, M.D., to the Health and Human Services Committee on Mental Retardation. Harris was sworn in to the position Jan. 12 for a two-year term.
Scientists at Johns Hopkins, New York University and Mount Sinai School of Medicine in New York have found a way to block the action of specific enzymes with a pivotal role in triggering cancers, hardening of the arteries and certain autoimmune diseases. (Nature Structural Biology, 1-01)
A common type of dwarfism may not be principally caused by a defect in the human growth hormone gene, as previously thought, but rather by a gene that controls the hormone's release into the bloodstream, according to scientists at the Johns Hopkins Children's Center and School of Medicine. (J. of Clinical Endocrinology & Metabolism, 1-01)
A scientific study of aviation crashes in the United States concludes that "pilot error" is a decreasing cause of crashes involving major airlines. (Aviation, Space, and Environmental Medicine, 1-01)
Deepening the mystery of autism's origins, a Johns Hopkins Children's Center study has failed to link the typical autistic child's fixation on spinning objects and constant whirling around to long-suspected damage to the brain's control center for movement, balance and equilibrium. (Journal of Autism and Developmental Disorders, 12-00)
Fludrocortisone, a drug prescribed to treat low blood pressure, has little or no effect on symptoms of chronic fatigue syndrome in adults when it is used as the only form of treatment, according to a joint study by the Johns Hopkins Children's Center and the National Institute of Allergy and Infectious Diseases (NIAID). (JAMA 1-01)
Hopkins researchers say early tests of a pancreatic cancer vaccine show it is safe and successful in reaching immune system cells. (J. of Clinical Oncology, 1-01)
The scientists at Johns Hopkins have now "engineered" human pluripotent stem cells (hPSCs) to form a new type of cell that not only holds the potential to develop into different tissues but also overcomes great drawbacks that have limited the use of hPSCs for disease therapy.
Mouse allergen, in the form of mouse urine or dander, is widely distributed in the inner city and may be a significant contributing factor to the childhood asthma epidemic in urban areas, according to two studies by Johns Hopkins researchers. (Journal of Allergy and Clinical Immunology, 12-00)
The Johns Hopkins University School of Medicine announced the formation of the Institute for Basic Biomedical Sciences. Uniting eight departments, several hundred scientists and initiating a $125 million funding campaign.
An operation developed at Johns Hopkins to halt blinding retinal damage from age-related macular degeneration improved vision in nearly half of the first 100 patients treated, according to a recent report in the American Journal of Ophthalmology.
Definity Health (formerly HealtheCare), which this fall launched a new consumer-driven health benefit, announced today that it has signed an agreement with Johns Hopkins University and Health System that will provide Definity Health members access to the academic center's extensive consumer health and wellness resources.
Scientists at Johns Hopkins have developed a gene therapy that, within a week, quells abnormal rhythms in pig hearts, the animal hearts most similar to human. It's believed to be the first use of gene therapy for cardiac arrhythmias, the researchers say, and one with "a strong possibility" of transfer to human heart disease. (Nature Medicine, 12-00)
A large nationwide study concludes that a drug called etanercept dramatically slows or even stops the progress of rheumatoid arthritis at the earliest stages of the disease, helping nearly three-quarters of those taking it. Etanercept also shows fewer side effects than the current best medicine. (NEJM)
Doctor, heal thyself? That seems the motto among a group of physicians surveyed by Johns Hopkins researchers: More than a third said they were unlikely to see a doctor on a regular basis. (Archives of Internal Medicine, 11-27-00)
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