Fewer Infections and Less Clotting Associated with Neutral Fluid Displacement Connector, Says Presentation at Oncology Meeting
Newswise — WASHINGTON, D.C. – Research on different types of IV connectors led a Johns Hopkins cancer center to pilot a “neutral pressure” IV connector, according to a scientific presentation at the annual meeting of the Oncology Nursing Society (ONS). Since the Hopkins poster was presented at the ONS meeting, The Johns Hopkins Hospital has adopted the IV connector hospital-wide.
In a four-month test, RyMed’s InVision-Plus® neutral connector reduced potentially deadly catheter-related bloodstream infections (CRBSIs) by 33.3% at the Johns Hopkins center.
Preventing CRBSIs is a major medical concern because U.S. patients suffer approximately 250,000 such infections a year. These often deadly infections have a mortality rate of 12% to 25% and cost an average of $56,000 to treat, according to the CDC.
According to the ONS presentation, a systematic literature review, conducted by the Sidney Kimmel Comprehensive Cancer Center at The Johns Hopkins Hospital, revealed that a neutral pressure IV connector can provide more protection against bloodstream infections than other connector types.
This review led the center to trial and then adopt the InVision-Plus® connector, (which RyMed calls its “zero fluid displacement” connector to distinguish it from other “neutral” connectors).
Clinicians decided this specific connector is better designed for infection prevention than other IV connectors, including others known as neutral, negative-pressure and positive-pressure. Positive-pressure connectors are already the subject of an FDA inquiry.
Researchers have identified several design elements common to positive and negative connectors that are associated with higher rates of CRBSIs. These include:
• Complicated fluid pathways with internal moving parts. The pathways have “dead spaces” that harbor bacteria, which can develop into infection-causing biofilm. The internal moving parts provide additional surfaces to which bacteria can adhere.
• Specific clamping sequences. Negative pressure connectors require one type of clamping sequence to prevent backflow of blood into the connector. Positive pressure connectors require a different sequence. If nurses accidentally perform the wrong sequence for the connector type (which is common), the resulting blood residue nurtures biofilm.
• Large priming volume, which is correlated with biofilm growth.
Hopkins researchers found RyMed’s InVision-Plus® to have a straight fluid pathway, and minimal priming volume and dead spaces as compared to other connectors. In addition, the InVision-Plus® has no moving parts in its fluid pathway and does not require a specific clamping sequence, because there is no backflow of blood into the connector’s interior.
Two additional advantages of the connector emerged in the study:
• Less clotting. The researchers documented substantially decreased use of alteplase for declotting catheters during the pilot period.
• No hub contamination. The CDC recommends that connector hubs be scrubbed with isopropyl alcohol to disinfect them. In a test under ultraviolet, the InVision-Plus® connector hub had no visible contamination, unlike the negative pressure connector then in use at the Johns Hopkins center. The InVision-Plus® has a smooth septum surface and a tight seal, which facilitate cleaning and eliminate gaps where bacteria can hide.
The poster’s authors were Marie Swisher, MSN, RN, AOCNS®, MiKaela Olsen, MS,RN, AOCNS®, and Kelly Weaver MSNc, RN. The ONS 38th Annual Congress was held April 25-28 in Washington, D.C.
For more information, access www.rymedtech.com.
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