In a world grappling with the complexities of mental health conditions like anxiety, depression, and PTSD, new research from Boston University neuroscientist Dr. Steve Ramirez and collaborators offers a unique perspective.
New research shows that languages make the same spatial distinctions using words like ‘this’ or ‘that’ based on whether they can reach the object they are talking about.
Cardionomic, Inc., a Minneapolis medical device company, is pleased to announce the completion of enrollment in both their STIM-ADHF and STOP-ADHF pilot studies.
At night in the Cerrado, Brazil’s savanna and second-largest biome, larvae of the click beetle Pyrearinus termitilluminans, which live in termite mounds, display green lanterns to capture prey attracted by the bright light.
Respiratory syncytial virus (RSV) vaccines recently approved for people 60 and older would dramatically reduce the disease’s significant burden of illness and death in the United States if they were widely adopted like annual influenza vaccines, a new study has found.
This paper provides an overview of how Artificial General Intelligence (AGI) can transform radiation oncology to elevate the standard of patient care, with the key insight being AGI's ability to exploit multimodal clinical data at scale.
Findings from a pioneering study in The American Journal of Pathology, published by Elsevier, reveal that administration of the neuropeptide α-melanocyte–stimulating hormone (α-MSH) promotes corneal healing and restores normal eye function to an otherwise degenerating and diseased cornea by providing protection against cell death and promoting cell regeneration.
Central features of human evolution may stop our species from resolving global environmental problems like climate change, says a new study led by the University of Maine.
Women from low socio-economic backgrounds consider themselves to be less talented than all other groups – even if they show the same performance levels.
Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel “genetic priority score” (GPS) that will integrate various types of human genetic data into a single easy-to-interpret score. The findings were described in the January 3 online issue of Nature Genetics [DOI: 10.1038/s41588-023-01609-2].
Studies have shown that drugs have an increased likelihood of success in clinical trials when the genes they target have been demonstrated to have genetic support. The new tool integrates multiple lines of genetic evidence to prioritize these drug targets.
Monoacylglycerols (MAGs) and diacylglycerols (DAGs) are nonionic molecules found in minor amounts in oils and fats, exhibiting hydrophilic and hydrophobic properties.
Palm Springs Downtown Park is an inviting 1.5-acre urban oasis for residents and visitors to Palm Springs, a design-forward desert destination nestled along the base of the San Jacinto Mountains along the southwestern boundary of the Coachella Valley in California’s Sonoran Desert of the USA.
Just as healthy organs are vital to our well-being, healthy organelles are vital to the proper functioning of the cell. These subcellular structures carry out specific jobs within the cell, for example, mitochondria power the cell and lysosomes keep the cell tidy.
In a study published online in Eco-Environment & Health on 13 October 2023, researchers from Zhejiang Shuren University and China Agricultural University have delved into these interactions, aiming to provide insights into the mechanisms and implications of plastic pollution on soil health and antibiotic resistance.
حدد الباحثون والمتعاونون في مايو كلينك بروتينًا تفرزه الخلايا المناعية والذي قد يقوم بدورٍ رئيسيٍ في ظهور مرضالتصلُّب الجانبي الضموري، المعروف أيضًا باسم مرض لو غيريغ. ووجد الفريق أيضًا أن العلاج التعديلي المناعي الذي يقوم بعملية إِحْصار للبروتين يمكنه استعادة الوظيفة الحركية في النماذج قبل السريرية. وتشير النتائج إلى أن البروتين، المعروف باسم أ5 إنتغرين (الذي يُنطق ألفا 5 إنتغرين)، هو مستهدف علاجي محتمل لعلاج مرض التصلُّب الجانبي الضموري.
Several whale species disappeared from Europe long before whaling became a major industry. Two of the most common species are no longer found here, and one of them is almost extinct.
Los investigadores y colaboradores de Mayo Clinic han identificado una proteína expresada en células inmunitarias que podría desempeñar un rol clave en el desarrollo de la esclerosis lateral amiotrófica (ELA), también conocida como enfermedad de Lou Gehrig. El equipo también descubrió que un tratamiento inmunomodulatorio que bloquea la proteína era capaz de restaurar la función motriz en modelos preclínicos. Los hallazgos indican que la proteína, conocida como integrina α5 (pronunciado integrina alfa 5), es un posible blanco terapéutico para la ELA.
Pesquisadores e colaboradores da Mayo Clinic identificaram uma proteína que é expressa por células imunológicas que pode desempenhar uma função importante no desenvolvimento daesclerose lateral amiotrófica (ELA), também conhecida como doença de Lou Gehrig. A equipe também descobriu que um tratamento imunomodulador que bloqueia a proteína conseguiu restaurar a função motora em modelos pré-clínicos. As descobertas sugerem que a proteína, conhecida como integrina α5 (pronunciada como integrina alfa 5), é um possível alvo terapêutico para ELA.
Researchers developed an artificial intelligence tool to quickly analyze gene activities in medical images and provide single-cell insight into diseases in tissues and tissue microenvironments.
The Matabele ants (Megaponera analis), which are widespread south of the Sahara, have a narrow diet: They only eat termites. Their hunting expeditions are dangerous because termite soldiers defend their conspecifics – and use their powerful mandibles to do so. It is therefore common for the ants to be injured while hunting.
The Lung Center at Mercy Medical Center is expanding to include Interventional Pulmonology (IP), essentially doubling the size of Mercy’s current Lung Center with greater access for pulmonary patients.
In a report just published in the journal Nature Climate Change, researchers argue that tackling inequality is vital in moving the world towards Net-Zero – because inequality constrains who can feasibly adopt low-carbon behaviours.
Farmers in sub-Saharan Africa need to diversify away from growing maize and switch to crops that are resilient to climate change and supply enough key micronutrients for the population, according to a major research study.
Monitoring glucose levels is one of the key elements in health monitoring. A research team has now developed a battery-independent fluorescent nanosensor based on single-wall carbon nanotubes and an inactive form of the enzyme glucose oxidase (GOx).
Our memories are rich in detail: we can vividly recall the color of our home, the layout of our kitchen, or the front of our favorite café. How the brain encodes this information has long puzzled neuroscientists.
An automated tool captures circulating tumor cells in children with central nervous system cancers. The tool could make it easier to identify tumors that don't respond to treatment.
Major cities on the U.S. Atlantic coast are sinking, in some cases as much as 5 millimeters per year – a decline at the ocean’s edge that well outpaces global sea level rise, confirms new research from Virginia Tech and the U.S. Geological Survey. Particularly hard hit population centers such as New York City and Long Island, Baltimore, and Virginia Beach and Norfolk are seeing areas of rapid “subsidence,” or sinking land, alongside more slowly sinking or relatively stable ground, increasing the risk to roadways, runways, building foundations, rail lines, and pipelines, according to a study published today in the Proceedings of the National Academies of Sciences.
Synthetic biology offers the opportunity to build biochemical pathways for the capture and conversion of carbon dioxide (CO2). Researchers at the Max-Planck-Institute for Terrestrial Microbiology have developed a synthetic biochemical cycle that directly converts CO2 into the central building block Acetyl-CoA.
Norway’s exports products derived from from tangle kelp (Laminoria hyperborea) and knotted kelp (Ascophyllum nodosu) to the tune of more than NOK 1 billion a year. The industry mainly extracts alginate from kelp, which is used in over 600 different products as diverse as paint, soft serve ice cream, sauces, bandages, nappies, acid reflux medicine and material for encapsulating cells and medicine.
A two-step screening protocol that combines clinical risk assessment with biomarker testing can more effectively identify which patients with Type 2 diabetes need medication to prevent heart failure, according to a study led by UT Southwestern Medical Center researchers.
Could healthy fats found in nuts and fish slow the progression of potentially deadly lung scarring known as pulmonary fibrosis and delay the need for lung transplants?
Researchers at Iowa State want to know whether different types and doses of exercise can improve mental health, either on their own or integrated into treatment plans. Two concurrent research projects funded by the National Institute of Mental Health will help fill in the gaps.
Discover the first images of cytonemes during mammalian neural development, serving as express routes to establish morphogen gradients and tissue patterning.
The number of Americans who watch or follow girls’ and women’s sports goes well beyond those who view TV coverage of women’s athletic events, a new study suggests. In fact, just over half of American adults spent some time watching or following female sports in the past year, the results showed
Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication asenapine, a possible therapeutic target for substance use and neuropsychiatric disorders. This discovery may pave the way for the development of improved medications targeting the same pathway. Their findings, detailed in the January 2 online issue of Nature Communications https://doi.org/10.1038/s41467-023-44601-4, show that a brain protein known as the TAAR1 receptor, a drug target known to regulate dopamine signaling in key reward pathways in the brain, differs significantly in humans compared to the preclinical rodent models on which drugs are typically tested. The study suggests considering species-specific differences in drug-receptor interactions and further investigation into ways asenapine affects the body, as steps toward potential therapeutic improvements.
Binghamton University, State University of New York Distinguished Professor and Nobel Laureate M. Stanley Whittingham has been chosen as the joint winner of the $3 million 2023 VinFuture Grand Prize in recognition of his contributions to the invention of lithium-ion batteries.
Researchers in the UNC School of Medicine’s Department of Psychiatry have found that enlarged perivascular spaces in the brains of babies, caused by an accumulation of excess cerebrospinal fluid, have a 2.2 times greater chance of developing autism later in life.
After a long day, there’s the age-old question of do we eat out or stay in? Over the last decade, that answer has increasingly shifted to eating out.
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