Scientists from the Florida campus of The Scripps Research Institute have been awarded more than $1.4 million from the National Cancer Institute of the National Institutes of Health to create a potential new drug to attack the malignant cells that cause chronic lymphocytic leukemia (CLL), the most common leukemia in the Western world.
Researchers at Moffitt Cancer Center and colleagues at Louisiana State University have developed a method for identifying aggressive prostate cancers that require immediate therapy. It relies on understanding the genetic interaction between single nucleotide polymorphisms (SNPs). The goal is to better predict a prostate cancer’s aggressiveness to avoid unnecessary radical treatment.
The motor neuron disease Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, progresses in a stepwise, sequential pattern which can be classified into four distinct stages, report pathologists with the Perelman School of Medicine at the University of Pennsylvania in the Annals of Neurology.
In early April, senior leaders from medical, law enforcement, military, and fire/rescue agencies met in Hartford, Connecticut, to discuss one question: how can first responders improve survival after a mass casualty event?
The results of three important studies have been published in the June issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
The ongoing global growth in the human population will inevitably crowd out mammals and birds and has the potential to threaten hundreds of species with extinction within 40 years, new research shows.
A chemical hormone released in the body as a reaction to stress could be a key trigger of the mechanism for the late onset of Alzheimer’s disease.
A clinical trial published in the July issue of Anesthesiology may shed some light on whether nitrous oxide (“laughing gas”) causes an increased risk for cardiac events, including heart attacks after surgery, particularly among high-risk patients.
The use of a less-expensive, longer-acting anesthetic (isoflurane) resulted in no difference in duration of hospitalization compared to the use of a more expensive, shorter-acting anesthetic (desflurane or sevoflurane), according to a study from the July issue of Anesthesiology.
Nitrous oxide (laughing gas) is one of the world’s oldest and most widely used anesthetics, but concerns that it raises the risk of a heart attack during surgery or soon afterward are unfounded, according to a new study from researchers at Washington University School of Medicine in St. Louis.
A Cornell University study offers further proof that the divergence of humans from chimpanzees some 4 million to 6 million years ago was profoundly influenced by mutations to DNA sequences that play roles in turning genes on and off.
Highly sensitive and accurate test detects cancer-related microRNA in blood of patients even before the development of colorectal cancer.
Half a dozen regions could provide some of the Western Hemisphere's more heavily used thoroughfares for mammals, birds and amphibians seeking cooler environments in a warming world. This is the first broad-scale study to consider how animals might travel when confronted with barriers like cities.
New research from wildlife ecologists at Michigan Technological University indicates that white-tailed deer may be making the soil in their preferred winter homes unfit to grow the very trees that protect them there.
A team led by UCLA researchers has conducted a major study on the importance of the speed of treatment when using a clot-busting drug, and found that treatment time has a profound influence on outcome.
Like a stealthy enemy, blast disease invades rice crops around the world, killing plants and cutting production of one of the most important global food sources. Now, a study by an international team of researchers sheds light on how the rice blast fungus, Magnaporthe oryzae, invades plant tissue. The finding is a step toward learning how to control the disease, which by some estimates destroys enough rice to feed 60 million people annually.
A research team led by Assia Shisheva, Ph.D., professor of physiology in Wayne State University’s School of Medicine, has made breakthrough advancements on a molecule that may provide more answers in understanding the precise molecular mechanisms by which insulin regulates glucose uptake in fat and muscle cells.
More than 1,500 pedestrians were estimated to be treated in emergency rooms in 2010 for injuries related to using a cell phone while walking, according to a new nationwide study.
Greater relevance to patients could be realized by focusing information on services that are predictable, nonurgent, and subject to deductibles (e.g., routine outpatient care for chronic diseases) rather than services that are unpredictable, emergent, or would exceed most deductibles (e.g., hospitalizations for life-threatening conditions).
Among patients with suspected stage I/II pulmonary sarcoidosis who were undergoing confirmation of the condition via tissue sampling, the use of the procedure known as endosonographic nodal aspiration compared with bronchoscopic biopsy, the current diagnostic standard, resulted in greater diagnostic yield, according to a study in the June 19 issue of JAMA.
The majority of children at risk of type 1 diabetes who developed 2 or more diabetes-related autoantibodies developed type 1 diabetes within 15 years, findings that highlight the need for research into finding interventions to stop the development of multiple islet autoantibodies, according to a study in the June 19 issue of JAMA.
Among children with juvenile idiopathic arthritis (JIA) who had undergone primary immunization, the use of a measles-mumps-rubella (MMR) booster compared with no booster did not result in worse JIA disease activity, according to a study in the June 19 issue of JAMA.
Magnetic resonance imaging (MRI) at the site of injection of a contaminated lot of a steroid drug to treat symptoms such as back pain resulted in earlier identification of patients with probable or confirmed fungal spinal or paraspinal infection, allowing early initiation of medical and surgical treatment, according to a study in the June 19 issue of JAMA.
In a study that included nearly 60,000 patients with acute ischemic stroke, thrombolytic treatment (to help dissolve a blood clot) that was started more rapidly after symptom onset was associated with reduced in-hospital mortality and intracranial hemorrhage and higher rates of independent walking ability at discharge and discharge to home, according to a study in the June 19 issue of JAMA.
State websites that publicly report health service prices rarely provide information that is relevant or usable for consumers, analysis in JAMA shows.
Labeling foods and beverages as less-healthy and taxing them motivates people to make healthier choices, finds a recent study in the American Journal of Preventive Medicine.
People with HIV are more likely to keep their scheduled medical appointments — and their disease under control — if they feel their physician listens, explains things clearly and knows them as a person, not just a “case,” new Johns Hopkins research suggests.
The age at which many children in the U.S. take their first sip of alcohol is surprisingly young, finds a new study in the Journal of Adolescent Health.
TED Talks, the most popular conference and events website in the world with over 1 billion informational videos viewed, provides academics with increased popular exposure but does nothing to boost citations of their work by peers, new research led by Indiana University has found.
University of Iowa ophthalmologists have tested a new drug to treat age-related macular degeneration in older patients. The researchers report that half of the eyes treated responded to the new drug, Eylea, with reduced fluid in the eyes, while one in three had improved vision after six months. Results appear in the American Journal of Ophthalmology.
For less than $100, University of Washington researchers have designed a computer-interfaced drawing pad that helps scientists see inside the brains of children with learning disabilities while they read and write.
Magnetic resonance imaging (MRI) of aortic atherosclerosis can predict the risk of heart attacks and other cardiovascular events in otherwise healthy individuals, researchers at UT Southwestern Medical Center have found.
Local chemical signals released by fat cells in the mammary gland appear to provide a crucial link between exposure to unrelenting social stressors early in life, and the subsequent development of aggressive breast cancer.
A research team led by UCSF scientists has found that exposure in infancy to nitrogen dioxide (NO2), a component of motor vehicle air pollution, is strongly linked with later development of childhood asthma among African Americans and Latinos.
A study released by the RN Work Project finds that newly licensed RNs who experience verbal abuse from nurse colleagues report lower job satisfaction, unfavorable perceptions of their work place and are more likely to leave their job than nurses who do not experience abuse.
Similar genetic variations occur in both overweight newborns and obese adults, a large study finds. The results will be presented Tuesday at The Endocrine Society’s 95th Annual Meeting in San Francisco.
A research team led by David Alland, MD, of UMDNJ-New Jersey Medical School, has discovered a drug that cripples tuberculosis bacteria (Mycobacterium tuberculosis) in a novel way, by dissolving the protecting fatty coating of the bacteria. The drug killed the bacterium in culture without the emergence of drug resistance.
Kids whose moms encourage them to exercise and eat well, and model those healthy behaviors themselves, are more likely to be active and healthy eaters, according to researchers at Duke Medicine. Their findings, published online in the International Journal of Obesity on June 18, 2013, remind parents that they are role models for their children, and underscore the importance of parental policies promoting physical activity and healthy eating.
Research from the University of Adelaide shows that iodized salt used in bread is not enough to provide healthy levels of iodine for pregnant women and their unborn children.
New research from the University of Adelaide shows that weight gain and increased head size in the first month of a baby's life is linked to a higher IQ at early school age.
Dana-Farber researchers find many men with low-risk, localized prostate cancers can safely choose observation instead of undergoing immediate treatment and a have better quality of life while reducing health care costs.
A social media push boosted the number of people who registered themselves as organ donors 21-fold in a single day, Johns Hopkins researchers found, suggesting social media might be an effective tool to address the stubborn organ shortage in the United States.
Aspirin is known to lower risk for some cancers, and a new study led by a UC San Francisco scientist points to a possible explanation, with the discovery that aspirin slows the accumulation of DNA mutations in abnormal cells in at least one pre-cancerous condition.
Researchers have found that antibodies against the human papillomavirus (HPV) may help identify individuals who are at greatly increased risk of HPV-related cancer of the oropharynx, which is a portion of the throat that contains the tonsils.
An international team led by scientists at The Scripps Research Institute, the Howard Hughes Medical Institute and Albert Einstein College of Medicine of Yeshiva University has identified a highly promising new anti-tuberculosis compound that attacks the tuberculosis (TB) bacterium in two different ways.
The lipidation states (or modifications) in certain proteins in the brain that are related to the development of Alzheimer disease appear to differ depending on genotype and cognitive diseases, and levels of these protein and peptides appear to be influenced by diet, according to a report published Online First by JAMA Neurology, a JAMA Network publication.
Differences in parental beliefs and attitudes regarding the effects of media on early childhood development may help explain increasing racial/ethnic disparities in child media viewing/habits, according to a study by Wanjiku F. M. Njoroge, M.D., of Seattle Children’s Hospital and the University of Washington, Seattle, and colleagues.
Hispanic preschoolers, children and adolescents viewed, on average about 12 foods ads per day on television in 2010, with the majority of these ads appearing on English-language TV, whereas fast-food represented a higher proportion of the food ads on Spanish-language television, according to a study published Online First by JAMA Pediatrics, a JAMA Network publication.
Age disparities exist in the continuum of care for patients with the human immunodeficiency virus (HIV) with people younger than 45 years less likely to be aware of their infection or to have a suppressed viral load, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.
Eating more red meat over time is associated with an increased risk of type-2 diabetes mellitus (T2DM) in a follow-up of three studies of about 149,000 U.S. men and women, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.
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