Feature Channels: Asthma

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2016 ACAAI Annual Meeting media registration open

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A team of Wayne State University researchers led by Karen MacDonell, Ph.D., assistant professor of family medicine and public health sciences at Wayne State’s School of Medicine, recently received a $2.66 million award from the National Heart, Lung and Blood Institute of the National Institutes of Health to address research limitations on interventions and ultimately improve asthma management in racial minority populations, particularly minority adolescents and young adults.

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Experiments designed to reveal how a protein protects the lungs from asthma-related damage suggest a new way to treat a rare disease marked by the inability of cells to break down fats, according to a report in EBioMedicine published online Oct. 25.

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Children who have been in the U.S. foster care system are at a significantly higher risk of mental and physical health problems – ranging from learning disabilities, developmental delays and depression to behavioral issues, asthma and obesity – than children who haven’t been in foster care, according to a University of California, Irvine sociologist.

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Researchers at the University of Illinois at Chicago have been awarded a $1.5 million grant from the Agency for Healthcare Research and Quality to study the impact of diagnostic error on outcomes for pulmonary patients and the use of lung-function testing in primary care. Studies suggest 30 to 50 percent of patients may have an incorrect diagnosis.

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A fully-automated rat maze built by Technion researchers could help scientists better understand how individuals cooperate, and how this process may go awry in the brains of people with disorders ranging from autism to schizophrenia.

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A team of researchers led by Richard Slatcher, Ph.D., associate professor of psychology in the College of Liberal Arts and Sciences at Wayne State University, has been awarded $2.74 million from the National Heart, Lung and Blood Institute of the National Institutes of Health for a project that aims to improve asthma management in youth.

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Benjamin Gaston, MD, a pediatric pulmonologist and researcher at Case Western Reserve University School of Medicine and University Hospitals Rainbow Babies & Children’s Hospital, has received a five-year, $13.3 million federal grant to develop optimized, personalized combinations of medications tailored to the unique needs of children with cystic fibrosis and severe asthma.

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A drug commonly used for the prevention of allergies and asthma someday could find new use in preventing liver disease and reducing the need for transplants, according to new research published in the October 2016 edition of the scientific journal Hepatology.

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Bronchodilator responsiveness, nasal inflammation and allergy were among the most significant baseline features that distinguished hard-to-control asthma in inner-city children and adolescents. These characteristics identified patients whose asthma did not improve throughout the year, despite adherence to the most intensive treatment based on national guidelines. Patients with hard-to-control asthma also had exacerbations peaking in the spring and fall, and more nighttime symptoms in the fall and winter.

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Researchers at Henry Ford Health System found that some children with asthma may need a tailored approach to their treatment. Researchers found that although the children experienced few allergies, they suffered from frequent asthma symptoms, despite receiving high doses of preventive medication.

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Some common sense tips from the American College of Allergy, Asthma and Immunology help keep kids with allergies and asthma safe on Halloween.

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A component of red wine and grapes can help control inflammation induced by a bacterial pathogen that is linked to upper respiratory tract inflammatory diseases such as asthma, chronic obstructive pulmonary diseases (COPD) and middle ear infection (otitis media), according to a study by researchers at Georgia State University.

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Pediatric otolaryngologist George Harris, MD, FACS, FAAP, who specializes in aerodigestive track disorders, has joined Loyola Medicine.

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With so much attention on coughs lately, do you ever wonder – when is a cough just a cough? When is it more? When is it something to really worry about? Allergist Bob Lanier, MD, executive director of the American College of Allergy, Asthma and Immunology has answers for you.

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The microbes living in a baby’s gut during its first month of life may directly impact the developing immune system, leading to a higher risk of allergies and asthma later in childhood. The findings highlight the importance of developing early interventions to improve microbial health in young infants.

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Sometimes children with asthma live hundreds of miles away from the nearest allergist and therefore may not be getting the best and most cost-effective care. According to a new study, treatment via telemedicine can be as effective as an in-person visit for children suffering from asthma.

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Children with mild, persistent asthma did not have worse asthma symptoms after taking acetaminophen (e.g., Tylenol) for pain or fever, compared to using ibuprofen (e.g., Advil), according to the results of a randomized, double-blind clinical trial recently published in the New England Journal of Medicine.

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To harness the power of technology to help children live healthier lives, the Karen S. Rheuban Center for Telehealth at University of Virginia Health System is helping create four school-based telehealth centers in Bland County and Martinsville.  The project aims to provide children with conditions from autism to asthma better access to specialists and coordinated care in a region with a shortage of healthcare providers.

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A post-marketing safety study mandated by the U.S. Food and Drug Administration has shown that a combination drug therapy for the treatment of asthma is safe and effective.

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Children with a history of food allergy have a high risk of developing asthma and allergic rhinitis during childhood as well. The risk increases with the number of food allergies a child might have. Research suggests that U.S. disease rates may be changing for the common childhood conditions asthma, allergic rhinitis and eczema.

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Results of a study published in PLOS ONE show that asthma risk increased 17 times when children who had bronchiolitis in the first two years of life also had a common variation of the Plasminogen activator inhibitor-1 (PAI-1) gene.

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A study from Emory AIDS researchers shows how the expected disease severity when someone is newly infected by HIV reflects a balance between the virus' invisibility to the host's immune system and its ability to reproduce.

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The majority of smokers who successfully switch to vaping say they have fewer respiratory infections, according to a study led by Queen Mary University of London (QMUL).

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House dust differences between Amish and Hutterite communities affect immune development and asthma risk, according to a study co-authored by UA Health Sciences researcher Dr. Donata Vercelli.

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WHAT: On August 10, the American Thoracic Society and the Marron Institute of Urban Management at New York University will share findings from their seminal report on the annual health benefits of meeting more protective air pollution standards as recommended by the ATS. The report focuses on ozone (O3), a component of smog, and fine particulate matter (PM2.5), tiny particles that are released when fuel is burned by motor vehicles and power plants, and also other sources.

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A joint University of Adelaide-Shanghai Jiao Tong University study has provided the first broad picture of the evolution and possible functions in the plant of pollen allergens.

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By probing the differences between two farming communities, an interdisciplinary team of researchers found that substances in the house dust from Amish, but not Hutterite, homes is associated with changes to immune cells that appear to protect children from developing asthma.

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Cancer immunotherapy drugs that block the inhibitory PD-1 pathway have shown success in clinical trials and are now FDA-approved for melanoma, lung cancer and bladder cancer. Yet many patients' tumors do not respond to these drugs.

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Parents need to start at home in order to control asthma and allergies when kids are at school. Uncontrolled asthma accounts for almost 14 million lost school days a year.

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Dr. Marina Reznik receives grant from NIH to examine impact of asthma guidelines promotion through technology-based intervention and care coordination

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Exposure to airborne dust and high temperatures are significant risk factors for bacterial meningitis, a new study by the University of Liverpool's Institute of Infection and Global Health has found.

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Scientists at the University of Southampton have discovered a potential and novel way of preventing asthma at the origin of the disease, a finding that could challenge the current understanding of the condition.

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People with asthma who live near bigger or larger numbers of active unconventional natural gas wells operated by the fracking industry in Pennsylvania are 1.5 to four times likelier to have asthma attacks than those who live farther away, new Johns Hopkins Bloomberg School of Public Health research suggests.

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The atomic structure of an elusive cold virus linked to severe asthma and respiratory infections in children has been solved by a team of researchers at the University of Wisconsin–Madison and Purdue University. The findings provide the foundation for future antiviral drug and vaccine development against the virus, rhinovirus C.

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WORCESTER, MA - A long non-coding RNA (lincRNA) - called lincRNA-EPS - responsible for regulating innate immunity has been identified by a team of scientists at the University of Massachusetts Medical School. Abundantly found in macrophages, lincRNA-EPS keeps the genes that trigger inflammation turned off until a pathogen is encountered. This discovery points to an unrecognized role for lincRNAs in the immune system and may lead to new insights into inflammatory diseases caused by uncontrolled immune responses such as lupus or inflammatory bowel disease.

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Children’s hospitals vary greatly in managing inpatients with asthma, according to researchers who analyzed hospital records in a large national database. Even when patients were grouped by characteristics such as age or severity of illness, hospitals differed significantly in inpatient costs, length of stay, and time spent in the intensive care unit (ICU).

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London's Great Smog of 1952 resulted in thousands of premature deaths and even more people becoming ill. The five December days the smog lasted may have also resulted in thousands more cases of childhood and adult asthma. Researchers from Columbia University's Mailman School of Public Health, the University of California, San Diego and University of Massachusetts studied how London's Great Smog affected early childhood health and the long-term health consequences. Findings are published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

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July 8, 2016─London’s Great Smog of 1952 resulted in thousands of premature deaths and even more people becoming ill. The five December days the smog lasted may have also resulted in thousands more cases of childhood and adult asthma, according to research published in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.

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Research from life scientists at The University of Manchester has shone new light on the way cells tune in to different inflammatory signals to understand what is happening in the body.

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Children covered by Medicaid and equally sick children not covered by Medicaid received essentially similar asthma treatment in a given pediatric hospital, according to a new study. In a national sample, researchers analyzed hospital practice patterns by comparing inpatient costs, lengths of stay and use of the intensive care unit

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Researchers have identified immune cells vital for protecting us from potentially fatal C. difficile infection. Surprisingly, those cells are often vilified for their role in causing asthma and allergies. But when it comes to C. difficile, they could be the difference in life and death.

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Previous exposure to the dengue virus may increase the potency of Zika infection, according to research from Imperial College London.

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Residents on the South Side say cancer, violence prevention and sexually transmitted infections are among their top health concerns, according to the latest comprehensive assessment conducted by the University of Chicago Medicine. The 2016 Community Health Needs Assessment (CHNA), published online in mid-June, also identifies diabetes among adults, pediatric asthma and pediatric obesity as other critical health issues faced by South Siders. In addition to uncovering the community’s health needs, the report also includes a plan to advance outreach, prevention and education in those six health areas.

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An innovative primary care-based asthma program improves identification of poorly controlled asthma among children and enhances treatment plans, compared to care provided during routine office visits.

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Stony Brook University researchers believe the key to discovering better treatments for chronic lung diseases sits with the p73 gene. They found that this gene is the master regulator of a cell type that is responsible for constantly cleaning our airways from inhaled pollutants, pathogens and dust.

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Researchers have developed an integrated, wearable system that monitors a user’s environment, heart rate and other physical attributes with the goal of predicting and preventing asthma attacks. The researchers plan to begin testing the system on a larger subject population this summer.

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Patients with obstructive lung disease who take inhaled corticosteroids (ICS) may be at greater risk for nontuberculous mycobacteria pulmonary disease (NTM PD), according to new research presented at the ATS 2016 International Conference.