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Newswise: University of Oklahoma Biomedical Engineering Researcher Ready to Transform TBI Surgery
Released: 19-Sep-2022 11:05 AM EDT
University of Oklahoma Biomedical Engineering Researcher Ready to Transform TBI Surgery
 University of Oklahoma, Gallogly College of Engineering

Patients who suffer a severe traumatic brain injury must undergo two surgeries: one to remove a part of the skull to allow the brain to swell and another surgery to replace the missing bone after brain swelling subsides. University of Oklahoma biomedical engineering researcher Michael Detamore and his team may have found a way to reduce the number of surgeries to just one.

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Released: 18-Sep-2022 12:00 PM EDT
Within-host virus evolution during the extended treatment of RSV infection with mutagenic drugs
 Preprints

Christopher Jr Illingworth, Alexandra Y Kreins, Adriana Margarit Soler, Tim Best, Patricia Dyal, Giovanna Lucchini, Kanchan Rao, Rachel Williams, Austen Jj Worth, Judith Breuer

Comment
Released: 18-Sep-2022 12:00 PM EDT
Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects
 Preprints

Holly Y Chen, Manju Swaroop, Samantha Papal, Anupam Mondal, Gregory Tawa, Florian Regent, Hiroko Shimada, Kunio Nagashima, Natalia de Val, Samuel G Jacobson, Wei Zheng, Anand Swaroop

Comment
Released: 18-Sep-2022 12:00 PM EDT
Differential expression of LINC00908 in amyotrophic lateral sclerosis.
 Preprints

Shahan Mamoor

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Released: 18-Sep-2022 12:00 PM EDT
Differential expression of SNX29P1 in amyotrophic lateral sclerosis.
 Preprints

Shahan Mamoor

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Released: 18-Sep-2022 12:00 PM EDT
Differential expression of LOC100507477 in amyotrophic lateral sclerosis.
 Preprints

Shahan Mamoor

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Released: 17-Sep-2022 12:00 PM EDT
Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation
 Preprints

Tianchi Xin, Sara Gallini, David Gonzalez, Lauren E. Gonzalez, Sergi Regot, Valentina Greco

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Newswise: Improved mineralized material can restore tooth enamel
Released: 16-Sep-2022 2:05 PM EDT
Improved mineralized material can restore tooth enamel
 Ural Federal University

Scientists have perfected hydroxyapatite, a material for mineralizing bones and teeth.

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Newswise: Lab experiments support COVID-19 bradykinin storm theory
Released: 16-Sep-2022 11:05 AM EDT
Lab experiments support COVID-19 bradykinin storm theory
 Oak Ridge National Laboratory

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.

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Released: 15-Sep-2022 12:00 PM EDT
The downstream PPARγ target LRRC1 participates in early-stage adipocytic differentiation
 Preprints

Xinping Wang, Jianyun Liu, Ting Wang, Baicheng Ma, Ping Wu, Xiaoyuan Xu, Jianjun Xiong

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Newswise: A Cut Above — Two Devices Are Teamed to Simplify, Quicken and Improve Ear Reconstruction
Released: 15-Sep-2022 10:00 AM EDT
A Cut Above — Two Devices Are Teamed to Simplify, Quicken and Improve Ear Reconstruction
 Johns Hopkins Medicine

Thanks to two novel tools developed by a Johns Hopkins Medicine resident and a former resident, the traditionally difficult surgery to create a replacement ear from a patient’s rib cartilage may soon be done faster, more simply and accurately.

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Released: 14-Sep-2022 12:00 PM EDT
NOTCH-pathway inactivation reprograms oral-stem-like cancer cells to JAK-STAT dependent state and provides the opportunity of synthetic lethality
 Preprints

Subhashis Ghosh, Paromita Mitra, Uday Saha, Arnab Ghosh, Nidhan Kumar Biswas, Shantanu Saha Roy, Moulinath Acharya, Sandeep Singh

Comment
Released: 14-Sep-2022 12:00 PM EDT
Clinicopathological correlation of p40/TTF1 co-expression in NSCLC and review of related literature
 Preprints

Lian Yang, Ming Xiao, Xian Li, Ya-Lan Wang

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Released: 14-Sep-2022 12:00 PM EDT
Trans-synaptic dwelling of SARS-CoV-2 particles perturbs neural synapse organization and function
 Preprints

Emma Partiot, Aurelie Hirschler, Sophie Colomb, Willy Lutz, Tine Claeys, Francois Delalande, Maika S Deffieu, Judith Roels, Joanna Bons, Domitille Callon, Laurent Andreoletti, Marc Labrousse, Frank Mj Jacobs, Valerie Rigau,

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Released: 14-Sep-2022 12:00 PM EDT
What are Factors Influencing on Life Space Mobility in Cancer Survivors after Hematopoietic Stem CellTransplantation? -Physical and Psychological Function, Physical Symptoms, Environment, or Employment Status?
 Preprints

Junichiro Inoue, Takashi Saito, Daisuke Makiura, Rei Ono, Hisayo Doi, Kimikazu Yakushijin, Yoshitada Sakai

Comment
Released: 14-Sep-2022 4:05 AM EDT
Bacteria from the sewer can become producers of hydrogen fuel
 Scientific Project Lomonosov

Scientists from the Federal Research Centre “Fundamentals of Biotechnology” of the Russian Academy of Sciences studied bacterium discovered in a wastewater treatment bioreactor. This microorganism has adapted to life in an acidic environment and breaks down carbohydrate-rich organic waste to form hydrogen.

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Released: 14-Sep-2022 4:05 AM EDT
Fungi, destroyers of tempera, can be used in pharmacy
 Scientific Project Lomonosov

The ability of microfungi to destruct organic compounds can be the object of envy for any processing plant. However, they sometimes destroy things that people prefer to keep safe – for example, paints of the masterpieces. The good news is that some of their biochemical reactions can be used in pharmacy.

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Released: 13-Sep-2022 4:55 PM EDT
DOE Announces $178 Million to Advance Bioenergy Technology
 Department of Energy, Office of Science

The U.S. Department of Energy (DOE) today announced $178 million for bioenergy research to advance sustainable technology breakthroughs that can improve public, health, help address climate change, improve food and agricultural production, and create more resilient supply chains. This funding will support cutting-edge biotechnology R&D of bioenergy crops, industrial microorganisms, and microbiomes. Alternative clean energy sources like bioenergy are playing a key role in reaching President Biden’s goal of a net-zero carbon economy by 2050.

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Newswise:Video Embedded johns-hopkins-team-finalist-in-collegiate-inventors-competition
VIDEO
Released: 13-Sep-2022 4:05 PM EDT
Johns Hopkins Team Finalist in Collegiate Inventors Competition
 Johns Hopkins University

The team developed a simpler and more comfortable brace to treat kids born with clubfoot.

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Released: 13-Sep-2022 12:00 PM EDT
What do the Transcriptome and Proteome of Menstrual Blood-derived Mesenchymal Stem Cells Tell us about Endometriosis?
 Preprints

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Released: 13-Sep-2022 11:45 AM EDT
The blood stem cell research that could change medicine of the future
 University of New South Wales

Biomedical engineers and medical researchers at UNSW Sydney have independently made discoveries about embryonic blood stem cell creation that could one day eliminate the need for blood stem cell donors.

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Released: 12-Sep-2022 12:00 PM EDT
Embryonic Vitamin D Deficiency Programs Hematopoietic Stem Cells to Induce Type 2 Diabetes
 Preprints

Carlos Bernal-Mizrachi, Jisu Oh, Amy E Riek, Kevin T Bauerle, Adriana Dusso, Kyle McNerney, Ruteja Barve, Isra Darwech, Jennifer Sprague, Clare Moynihan, Rong M Zhang, Ting Wang, Xiaoyun Xing, Daofeng Li,

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Released: 12-Sep-2022 12:00 PM EDT
A phase II study of chidamide, cytarabine, aclarubicin, granulocyte colony-stimulating factor, and donor lymphocyte infusion for relapsed acute myeloid leukemia and myelodysplastic syndrome after allogeneic hematopoietic stem cell transplantation
 Preprints

Yan Wei, Lijun Wang, Chengying Zhu, Honghua Li, Jian Bo, Ran Zhang, Ning Lu, Yongli Wu, Xiaoning Gao, Liping Dou, Daihong Liu, Chunji Gao

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Newswise: Call for Papers – The International Halal Science and Technology Conference 2022 (IHSATEC): 15th Halal Science Industry and Business (HASIB)
Released: 12-Sep-2022 8:55 AM EDT
Call for Papers – The International Halal Science and Technology Conference 2022 (IHSATEC): 15th Halal Science Industry and Business (HASIB)
 Chulalongkorn University

The Halal Science Center, Chulalongkorn University, and Research Synergy Foundation, invite all to attend “The International Halal Science and Technology Conference 2022 (IHSATEC): 15th Halal Science Industry and Business (HASIB)” and has opened up a call for papers. The conference sessions will be on December 15-16, 2022 at Chulalongkorn University, Bangkok, Thailand.

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Newswise: Biologists Create Nanogold for Medicine and Agronomy
Released: 12-Sep-2022 3:05 AM EDT
Biologists Create Nanogold for Medicine and Agronomy
 Scientific Project Lomonosov

RUDN biologists in collaboration with scientists from Iran have obtained gold nanoparticles using harmless fungi living on a peach tree. The resulting particles proved to be useful in the fight against a pathogenic fungus that infects rice and potatoes. Potentially, nanoparticles can be used in medicine.

Comment
Released: 10-Sep-2022 12:00 PM EDT
Developmental role of macrophages modelled in human pluripotent stem cell derived intestinal tissue
 Preprints

Gregor Andelfinger, Andrew Song, Renata H.M. Sindeaux, Yuanyi Li, Hicham Affia, Tapan Agnihotri, Severine Leclerc, Patrick Piet van Vliet, Mathieu Colas, Jean-Victor Guimond, Natasha Patey, Jean-Sebastien Joyal, Elie Haddad, Luis Barreiro

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Released: 10-Sep-2022 12:00 PM EDT
X-linked adrenoleukodystrophy patient fibroblast-iPSC-derived astrocytes reveal phenotype-specific metabolic, inflammatory, and microRNA alterations
 Preprints

Parveen Parasar, Navtej Kaur, Laila Poisson, Jaspreet Singh

Comment
Released: 9-Sep-2022 12:00 PM EDT
Engineering High-Quality Cartilage Microtissues using Hydrocortisone Functionalised Microwells
 Preprints

Ross Burdis, Gabriela Soares Kronemberger, Daniel J Kelly

Comment
Released: 9-Sep-2022 12:00 PM EDT
Genetically Engineered Human Pituitary Corticotroph Tumor Organoids Exhibit Divergent Responses To Glucocorticoid Receptor Modulators
 Preprints

Saptarshi Mallick, Jayati Chakrabarti, Jennifer Eschbacher, Andreas G Moraitis, Andrew E Greenstein, Jared Churko, Kelvin W Pond, Antonia Livolsi, Curtis A Thorne, Andrew S Little, Kevin Cj Yuen, Yana Zavros

Comment
Released: 9-Sep-2022 12:00 PM EDT
Platelet factor 4 induces bone loss by inhibiting the integrin α5-FAK-ERK pathway
 Preprints

Hao Liu, Qiwei Zhang, Ranli Gu, Wei Li, Yunsong Liu, Yongsheng Zhou

Comment
Released: 9-Sep-2022 12:00 PM EDT
Macromolecular crowding facilitates rapid fabrication of intact, robust cell sheets
 Preprints

Shuwen Guan, Shipeng Wu, Gang Li, Jiangwei Xiao, Botao Gao

Comment
Released: 9-Sep-2022 12:00 PM EDT
Unselfish traits and social decision-making patterns characterize six populations of real-world extraordinary altruists
 Preprints

Shawn A Rhoads, Kruti Vekaria, Katherine O'Connell, Hannah S Elizabeth, David Gertler Rand, Megan Kozak Williams, Abigail Marsh

Comment
Released: 9-Sep-2022 12:00 PM EDT
Apelin Stimulation of the Perivascular MuSC Niche Enhances Endogenous Repair in Muscular Dystrophy
 Preprints

Emmeran Le Moal, Yuguo Liu, Jasmin Collerette-Tremblay, Simon Dumontier, Joel Boutin, Junio Dort, Zakaria Orfi, Joris Michaud, Hugo Giguere, Alexandre Desroches, Francois Vezina, Sonia Bedard, Frederic Balg, Philippe Sarret,

Comment
Released: 9-Sep-2022 12:00 PM EDT
Impact of pretransplant donor-specific anti-HLA antibodies in HLA-mismatched peripheral blood stem cell transplantation
 Preprints

Takeshi Hagino, Kazuhiro Ikegame, Hidenori Tanaka, Yoshinobu Kanda, Katsuji Kaida, Takahiro Fukuda, Yukio Kondo, Maho Sato, Noriko Doki, Hirohisa Nakamae, Ken-Ichi Matsuoka, Yasuo Mori, Hideki Sano, Tetsuya Eto,

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Released: 9-Sep-2022 12:00 PM EDT
Placental mesenchymal stem cells ameliorate NLRP3 inflammasome induced ovarian insufficiency by modulating macrophage M2 polarization
 Preprints

Dongmei Chen, Na Hu, Shasha Xing, Li Yang, Feiyan Zhang, Songlin Guo, Shudan Liu, Xiaona Ma, Xueyun Liang, Huiming Ma

Comment
Released: 9-Sep-2022 12:00 PM EDT
Mediator 1 ablation induces enamel-to-hair lineage conversion through enhancer dynamics
 Preprints

Roman Thaler, Keigo Yoshizaki, Thai Nguyen, Satoshi Fukumoto, Pamela DenBesten, Daniel D Bikle, Yuko Oda

Comment
Released: 9-Sep-2022 12:00 PM EDT
Stem Cell Therapy Improves Human Islet Graft Survival in Mice via Regulation of Macrophages
 Preprints

Wenyu Gou, Wei Hua, Lindsay Swaby, Wanxing Cui, Erica Green, Katherine Morgan, Charlie Strange, Hongjun Wang

Comment
Released: 9-Sep-2022 12:00 PM EDT
p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation
 Preprints

Justine Creff, Ada Nowosad, Anne Prel, Anne Pizzocaro, Marion Aguirrebengoa, Nicolas Duquesnes, Caroline Callot, Thomas Jungas, Christine Dozier, Arnaud Besson

Comment
Released: 9-Sep-2022 12:00 PM EDT
Identification of the Metaphyseal Skeletal Stem Cell
 Preprints

Guan Yang, Qi He, Xiaoxiao Guo, Rong-Yu Li, Jingting Lin, Wanyu Tao, Wenjia Liu, Huisang Lin, Mingchuan Tang, Shilai Xing, Yini Qi, Yanli Peng, Lei Dong, Jing-Dong J Han, Bin

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Newswise: Ceramic material could improve MRIs by enabling faster times, better images
Released: 9-Sep-2022 9:30 AM EDT
Ceramic material could improve MRIs by enabling faster times, better images
 Penn State Materials Research Institute

An academic/enterprise partnership that includes Penn State researchers is developing a new dielectric material to enable magnetic resonance imaging (MRI) machines with shorter scan times and higher image resolutions, good news for cutting the cost of MRI scans for the hospitals and for patients who struggle with MRI-related anxiety.

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Released: 8-Sep-2022 12:00 PM EDT
A time and single-cell resolved model of hematopoiesis
 Preprints

Iwo Kucinski, Joana Campos, Melania Barile, Francesco Severi, Natacha Bohin, Pedro N Moreira, Lewis Allen, Hannah Lawson, Myriam L R Haltalli, Sarah J Kinston, Dónal O'Carroll, Kamil R Kranc, Berthold Göttgens

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Released: 7-Sep-2022 12:00 PM EDT
Single cell RNA sequencing analysis of mouse cochlear supporting cell transcriptomes with activated ERBB2 receptor, a candidate mediator of hearing restoration mechanisms.
 Preprints

Dorota Piekna-Przybylska, Daxiang Na, Jingyuan Zhang, Cameron Baker, John Ashton, Patricia White

Comment
Released: 7-Sep-2022 12:00 PM EDT
ESDR579 - Clinical grade human pluripotent stem cells derived engineered skin substitutes promote keratinocytes wound closure in vitro
 Preprints

Sophie Domingues, Annabelle Darle, Yolande Masson, Manoubia Saidani, Emilie Lagoutte, Ana Bejanariu, Julien Coutier, Raif Eren Ayata, Marielle Bouschbacher, Marc Peschanski, Lemaitre Gilles, Christine Baldeschi

Comment
Released: 7-Sep-2022 9:00 AM EDT
MD Anderson and Virogin Biotech announce strategic collaboration to accelerate oncolytic virus research and development for treating advanced cancers
 University of Texas MD Anderson Cancer Center

MD Anderson and Virogin Biotech today announced a strategic collaboration to accelerate the development of oncolytic virus therapies for advanced cancers.

Comment
Released: 6-Sep-2022 12:00 PM EDT
ATF3 Preserves Skeletal Muscle Stem Cell Quiescence by Preventing Precocious Activation
 Preprints

Suyang Zhang, Yile Huang, Feng Yang, Liangqiang He, Yuying Li, Yi Ching Esther Wan, Yingzhe Ding, Kui Ming Chan, Ting Xie, Hao Sun, Huating Wang

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Released: 6-Sep-2022 12:00 PM EDT
3D Human Induced Pluripotent Stem Cell-derived Bioengineered Skeletal Muscles for Tissue, Disease and Therapy Modelling
 Preprints

Luca Pinton, Moustafa Khedr, Valentina M. Lionello, Shilpita Sarcar, Sara M. Maffioletti, Sumitava Dastidar, Elisa Negroni, Sungwoo Choi, Noreen Khokhar, Anne Bigot, John R. Counsell, Andreia Sofia Bernardo, Peter S. Zammit, Francesco Saverio Tedesco

Comment
Released: 6-Sep-2022 12:00 PM EDT
Elevation of cAMP upregulates Cav1.2 expression and promotes odontogenic differentiation of dental pulp stem cells
 Preprints

Changlong Jin, Yanqin Ju, Shouliang Zhao, Han Xie

Comment
Released: 6-Sep-2022 12:00 PM EDT
CRISPR screens in 3D assembloids reveal disease genes associated with human interneuron development
 Preprints

Xiangling Meng, David Yao, Kevin W Kelley, Noah Reis, Mayuri V Thete, Shravanti Kulkarni, Michael C Bassik, Sergiu P Pasca

Comment
Released: 6-Sep-2022 12:00 PM EDT
Photoelectrochemical imaging of action potentials for single cardiomyocytes through contact force manipulation of organoids
 Preprints

Rachel Jacques, Bo Zhou, Emilie Marhuenda, Jon Gorecki, Anirban Das, Thomas Iskratsch, Steffi Krause

Comment
Newswise: Artificial Breathing System Reveals Alveoli Function in Lungs
31-Aug-2022 2:05 PM EDT
Artificial Breathing System Reveals Alveoli Function in Lungs
 American Institute of Physics (AIP)

In Biomicrofluidics, scientists in China created a model alveolar system that mimics the breathing action of the human lung and allows visualization of flow patterns within the alveoli. The chip they designed includes tubes arranged like the structure of a bifurcation point in the bronchial network. The upper layer of the chip is made of a flexible polymer molded into small tubes that mimic the alveolar structure. The lower layer is glass, which allows the authors to visualize fluid flow through the tubes.

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