Differential expression of WNT16 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Feature Channels: Biotech
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Released: 20-Oct-2022 12:00 PM EDT
Released: 20-Oct-2022 12:00 PM EDT
Differential expression of PSMD5-AS1 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 20-Oct-2022 12:00 PM EDT
Differential expression of STX17-AS1 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 20-Oct-2022 12:00 PM EDT
Differential expression of DUSP6 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 20-Oct-2022 12:00 PM EDT
Differential expression of ALOX15 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 20-Oct-2022 12:00 PM EDT
Differential expression of CXCL8 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 18-Oct-2022 12:00 PM EDT
Ostrich Eggshell – Hydroxyapatite Composite as a Safe Scaffold with Osteoinductive Properties
PreprintsFarideh Alahgahi, Esmail Fattahi, Mohsen Saeidi, Mir Mahmoud Mortazavi
Released: 17-Oct-2022 12:00 PM EDT
Human organoid model of PCH2a recapitulates brain region-specific pathology
PreprintsTheresa Kagermeier, Stefan Hauser, Kseniia Sarieva, Lucia Laugwitz, Samuel Groeschel, Wibke Janzarik, Zeynep Yentuer, Katharina Becker, Ludger Schoels, Ingeborg Kraegeloh-Mann, Simone Mayer
Released: 17-Oct-2022 12:00 PM EDT
Differential expression of TXNRD2 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 17-Oct-2022 12:00 PM EDT
Differential expression of BIK in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 17-Oct-2022 12:00 PM EDT
Development of a highly sensitive immunoassay to measure ataxin2 as a target engagement marker in Spinocerebellar Ataxia Type 2
PreprintsJessica Bux, Nesli Ece Sen, Isa-Maria Klink, Stefan Hauser, Ludger Schöls, Georg Auburger, Olaf Horst Riess, Jeannette Hübener-Schmid
Released: 17-Oct-2022 12:00 PM EDT
Differential expression of COMT in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 17-Oct-2022 12:00 PM EDT
Leak current, even with gigaohm seals, can cause misinterpretation of stem cell-derived cardiomyocyte action potential recordings
PreprintsAlexander Phillip Clark, Michael Clerx, Siyu Wei, Chon Lok Lei, Teun de Boer, Gary R Mirams, David J Christini, Trine Krogh-Madsen
Released: 17-Oct-2022 12:00 PM EDT
Effective NGN2-based neuronal programming of hiPSCs in an automated microfluidic platform
PreprintsSilvia Angiolillo, Sara Micheli, Onelia Gagliano
Released: 17-Oct-2022 12:00 PM EDT
Type 2 Inflammation Drives an Airway Basal Stem Cell Program Through Insulin Receptor Substrate Signaling
PreprintsXin Wang, Nils Hallen, Minkyu Lee, Sachin Samuchiwal, Qihua Ye, Kathleen Buchheit, Alice Maxfield, Rachel Roditi, Regan Bergmark, Neil Bhattacharyya, Tessa Ryan, Deb Gakpo, Soumya Raychaudhuri, Dan Dwyer,
Released: 17-Oct-2022 12:00 PM EDT
Mitochondrial complex I controls blood brain barrier permeability
PreprintsGavin M Davis, Estelle Juere, Jerrard M Hayes, Gavin P Davey
Released: 17-Oct-2022 12:00 PM EDT
A novel brain penetrant PDGFRα inhibitor HY-008 is effective against glioblastoma
PreprintsChenxin Xu, Haizhong Feng, Weilin Sun
Released: 17-Oct-2022 12:00 PM EDT
MicroRNAs 7/17/155 As A Potential Breast Tumor Stemness miRNA Cluster: Detection of Breast Cancer Grade Specific miRNA-mRNA Interaction Network Inspiration from Mammary Gland Development
PreprintsSaeed Khodayari, Hamid Khodayari, Haniyeh Jallali, Elnaz Saeedi, Ali Faryabi, Meghdad Yeganeh, Ahad Mohammadnejad, Amirnader Emami Razavi, Mohammad Dashtkoohi, Farimah Hadjilooei, Reza Shirkoohi, Ramesh Omranipour, Karim Nayernia, Habibollah Mahmoodzadeh
Released: 17-Oct-2022 12:00 PM EDT
Inhibition of the NLRP3 Inflammasome Activation/Assembly through the Activation of the PI3K Pathway by Naloxone Protects Neural Stem Cells from Ischemic Condition
PreprintsJi Young Kim, Na-Young Choi, Mina Hwang, Seong-Ho Koh
Released: 17-Oct-2022 12:00 PM EDT
Single-cell Landscape Analysis of the Circulating Human B Cell Pool under Selective Pressure of Allogeneic Stem Cell Transplantation
PreprintsJonathan C Poe, Jiyuan Fang, Dadong Zhang, Marissa R Lee, Rachel A DiCioccio, Hsuan Su, Xiaodi Qin, Jennifer Zhang, Jonathan Visentin, Sonali J Bracken, Vincent T Ho, Kathy S Wang, Jeremy J Rose, Steven Z Pavletic,
Released: 17-Oct-2022 12:00 PM EDT
Poly(ε-caprolactone)-based nanofibrous scaffold incorporated with decellularized bone extracellular matrix as a potential strategy for bone regeneration
PreprintsMing Zhang, Quan Zhou, Qiangsheng Dong, Jue Zhang, Xin Zhou, Hao Huang, Junchen Bao, Hongjian Shan, Furong Sun, Liangliang Li
Released: 17-Oct-2022 10:05 AM EDT
Protein IDs, drug candidates, show promise for COVID science
Cornell UniversityA highly innovative method using the latest technology has generated a comprehensive list of SARS-CoV-2 viral and human proteins that interact with each other, with one such interaction showing the virus directly influencing proteins that regulate the human immune system.
Released: 14-Oct-2022 12:00 PM EDT
Predictive nonlinear modeling of malignant myelopoiesis and tyrosine kinase inhibitor therapy
PreprintsJonathan Dennis Rodriguez, Abdon Iniguez, Nilamani Jena, Prasanthi Tata, Joan Liu, Arthur D Lander, John Lowengrub, Richard Van Etten
Released: 14-Oct-2022 12:00 PM EDT
A stem cell zoo uncovers intracellular scaling of developmental tempo across mammals
PreprintsJorge Lazaro, Maria Costanzo, Marina Sanaki-Matsumiya, Charles Girardot, Masafumi Hayashi, Katsuhiko Hayashi, Sebastian Diecke, Thomas B Hildebrandt, Giovanna Lazzari, Jun Wu, Stoyan G Petkov, Rudiger Behr, Vikas Trivedi, Mitsuhiro M
Released: 14-Oct-2022 12:00 PM EDT
Machine-guided cell-fate engineering
PreprintsEvan M Appleton, Jenhan Tao, Gregory J Fonseca, Songlei Liu, Christopher H Glass, George M Church
Released: 14-Oct-2022 12:00 PM EDT
An integrated cell barcoding and computational analysis pipeline for scalable analysis of differentiation at single-cell resolution
PreprintsSophie Shen, Tessa Werner, Yuliangzi Sun, Woo Jun Shim, Samuel Lukowski, Stacey Andersen, Han Sheng Chiu, Di Xia, Xiaoli Chen, Duy Pham, Zezhuo Su, Joseph E Powell, Patrick P. L. Tam, Mikael Boden,
Released: 14-Oct-2022 12:00 PM EDT
Gamma Irradiation Processing on 3D PCL Devices - A Preliminary Biocompatibility Assessment
PreprintsFernando Guedes, Mariana V. Branquinho, Sara Biscaia, Rui D. Alvites, Ana C. Sousa, Bruna Lopes, Patrícia Sousa, Alexandra Rêma, Irina Amorim, Fátima Faria, Tatiana M. Patrício, António Bugalho, Nuno Alves, Ana C. Maurício
Released: 13-Oct-2022 1:05 PM EDT
Fast-food rubbish solution in sustainable seaweed-based wrapper
Flinders UniversityFlinders University materials researchers and pioneering German biomaterials developer one • fıve are using seaweed extracts to develop next-generation biopolymer coating materials that could solve packaging waste dilemmas for the fast-food industry.
Released: 13-Oct-2022 12:00 PM EDT
Surgical efficacy and quality of wide resection of the pelvic peritoneum in patients with epithelial ovarian cancer
PreprintsAkiho Nishimura, Takeshi Motohara, Jun Morinaga, Yutaka Iwagoi, Mayuko Yamamoto, Munekage Yamaguchi, Yo Miyahara, Hironori Tashiro, Hidetaka Katabuchi
Released: 13-Oct-2022 12:00 PM EDT
HDAC8-mediated inhibition of EP300 drives a neural crest-like transcriptional state that increases melanoma brain metastasis
PreprintsMichael F Emmons, Richard L Bennett, Alberto Riva, Chao Zhang, Robert Macaulay, Daphne Dupere-Richer, Bin Fang, Edward Seto, John Koomen, Jiannong Li, Ann Chen, Peter Forsyth, Jonathan Licht, Keiran S.M. Smalley
Released: 13-Oct-2022 12:00 PM EDT
Ablation of ZC3H11A causes early embryonic lethality and dysregulation of metabolic processes
Preprints
Released: 13-Oct-2022 12:00 PM EDT
Use of high-plex data reveals novel insights into the tumour microenvironment of clear cell renal cell carcinoma
PreprintsRaffaele De Filippis, Georg Wolflein, In Hwa Um, Peter D Caie, Sarah Warren, Andrew White, Elizabeth Suen, Emily To, Ognjen Arandjelovic, David J Harrison
Released: 13-Oct-2022 12:00 PM EDT
Concurrent temporal patterning of neural stem cells in the fly visual system
PreprintsUrfa Arain, Ishrat Maliha Islam, Priscilla Valentino, Ted Erclik
Released: 13-Oct-2022 12:00 PM EDT
Advanced physiological maturation of iPSC-derived human cardiomyocytes using an algorithm-directed optimization of defined media components
PreprintsNeal I. Callaghan, Lauren J. Durland, Wenliang Chen, Uros Kuzmanov, Maria Zena Miranda, Zahra Mirzaei, Ronald G. Ireland, Erika Yan Wang, Karl Wagner, Michelle M. Kim, Julie Audet, Paul Santerre, Anthony O. Gramolini, Filio Billia,
Released: 12-Oct-2022 1:05 PM EDT
Bionic Pancreas Improves Type 1 Diabetes Management in Kids and Adults
Ann and Robert H. Lurie Children's Hospital of ChicagoA device known as a bionic pancreas, which uses next-generation technology to automatically deliver insulin, was more effective at maintaining blood glucose (sugar) levels within normal range than standard-of-care management among people with type 1 diabetes, a new multicenter clinical trial has found.
Released: 12-Oct-2022 12:00 PM EDT
An Anti-EpCAM Monoclonal Antibody (EpMab-37-mG2a-f) Exerts Antitumor Activity against Breast Cancer in Mouse Xenograft Model
PreprintsTeizo Asano, Hiroyuki Suzuki, Guanjie Li, Tomokazu Ohishi, Manabu Kawada, Takeo Yoshikawa, Tomohiro Tanaka, Mika K. Kaneko, Yukinari Kato
Released: 12-Oct-2022 12:00 PM EDT
Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs
PreprintsDulce Lima Cunha, Jonathan Eintracht, Philippa Harding, Jo Huiqing Zhou, Mariya Moosajee
Released: 12-Oct-2022 12:00 PM EDT
CD146+ umbilical cord mesenchymal stem cells exhibit higher immunomodulatory activity and therapeutic efficacy in septic mice
PreprintsLin Zhang, Xiaoxu Zhang, Yubin Liu, Weiyuan Zhang, Chu-Tse Wu, Lisheng Wang
Released: 12-Oct-2022 12:00 PM EDT
Temporal Evolution and Differential Patterns of Cellular Reconstitution after Therapy for Childhood Cancers
PreprintsGina Hofmann, Jakob Zierk, Bettina Sobik, Zofia Wotschofsky, Stephanie Sembill, Manuela Krumbholz, Markus Metzler, Axel Karow
Released: 12-Oct-2022 12:00 PM EDT
Trophoblast stem-cell-derived exosomes alleviate cardiotoxicity of Doxorubicin via improving Mfn2-mediated mitochondrial fusion
PreprintsJunfeng Duan, Xiaoli Liu, Song Shen, Xi Tan, Yi Wang, Lian Wang, Lina Kang, Kun Wang, Zhonghai Wei, Yu Qi, Lei Hu, Biao Xu, Rong Gu
Released: 12-Oct-2022 12:00 PM EDT
Treatment of herpes zoster with brivudin in immunocompromised children
PreprintsClara Vogel, Laura Wetzel, Peter Wutzler, Bernd Gruhn
Released: 11-Oct-2022 12:00 PM EDT
Robust Advanced Modeling and Scheduling System (RAMS): From Space Exploration to Real-World Biomanufacturing
PreprintsMichael Saint-Guillain, Isabelle Sansdrap, Michaël Brion, Eric Pauly
Released: 11-Oct-2022 12:00 PM EDT
Production of cells with activated immunogenic properties from hematopoietic and non-hematopoietic progenitors by activation specific protective pathways
PreprintsIskra Ventseslavova Sainova, Iliana Ilieva, Milen Hristov, Tzvetanka Markova
Released: 11-Oct-2022 10:05 AM EDT
New Master’s Degree Prepares Future Regenmed Scientists, Business Leaders
Wake Forest Institute for Regenerative MedicineA new master’s degree program to prepare next and future generations of STEM professionals and business leaders for the regenerative medicine field has been established at the Wake Forest University School of Medicine in collaboration with regenerative medicine experts at the Wake Forest Institute for Regenerative Medicine (WFIRM).
Released: 10-Oct-2022 3:45 PM EDT
Gene Therapy Rapidly Improves Night Vision in Adults with Congenital Blindness
Perelman School of Medicine at the University of PennsylvaniaPatients’ low-light sensitivity improved by factors of thousands in a clinical trial
Released: 10-Oct-2022 2:05 PM EDT
Self-teaching AI uses pathology images to find similar cases, diagnose rare diseases
Brigham and Women’s HospitalNew model acts as search engine for large databases of pathology images, helping to identify rare diseases and determine patients likely to respond to similar therapies.
Released: 10-Oct-2022 12:00 PM EDT
Human endometrium derived induced pluripotent stem cells are amenable to directed erythroid differentiation
PreprintsHyun Kyung Kim, Si Hyun Cho, Young Sik Choi, Byung Seok Lee, Sinyoung Kim, Joo Hyun Park
Released: 10-Oct-2022 12:00 PM EDT
Differential expression of SGPP2 in amyotrophic lateral sclerosis.
PreprintsShahan Mamoor
Released: 10-Oct-2022 12:00 PM EDT
PRAMEL7/CUL2 axis regulates NuRD stability to establish ground-state pluripotency in embryonic stem cells
PreprintsMeneka Rupasinghe, Cristiana Bersaglieri, Deena M. Leslie Pedrioli, Patrick G.A. Pedrioli, Michael O. Hottiger, Paolo Cinelli, Raffaella Santoro
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