Trending news releases with the most views in a single day. Topics include: nanotech treating cancer, immunology, autism, patient monitoring, research ethics, lingering effects of dispersant in Gulf of Mexico, wildlife conservation.
University of Illinois researchers found that Sulfolobus islandicus can go dormant, ceasing to grow and reproduce, in order to protect themselves from infection by Sulfolobus spindle-shaped virus 9 (SSV9). The dormant microbes are able to recover if the virus goes away within 24 to 48 hours—otherwise they die.
A team of Whitehead Institute scientists has discovered that during division, stem cells distinguish between old and young mitochondria and allocate them disproportionately between daughter cells.
By engineering antibacterial enzymes, Dartmouth investigators led by Karl Griswold, PhD are using novel strategies to target the prevalent drug-resistant bacterium Staphylococcus aureus.
CENTOGENE AG (“CENTOGENE”) announces the launch of the world’s largest genetic mutation database for rare diseases, CentoMD®.
A particular molecular pathway permits stem cells in pediatric bone cancers to grow rapidly and aggressively, according to researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center.
Lung diseases like emphysema and pulmonary fibrosis are common among people with malfunctioning telomeres, the “caps” or ends of chromosomes. Now, researchers from Johns Hopkins say they have discovered what goes wrong and why.
A new study out of West Virginia University suggests antioxidants may play a key role in reducing the long-term effects of concussions and could potentially offer a unique new approach for treatment.
A team led by James Eberwine was named one of 16 finalists in the first phase of the Follow that Cell Challenge funded by the National Institutes of Health (NIH).
Researchers at UC Davis have illuminated an important distinction between mice and humans: how human livers heal. The difference centers on a protein called PPARα, which activates liver regeneration. Normally, mouse PPARα is far more active and efficient than the human form, allowing mice to quickly regenerate damaged livers. However, the research shows that protein fibroblast growth factor 21 (FGF21) can boost the regenerative effects of human PPARα. The findings suggest that the molecule could offer significant therapeutic benefits for patients who have had a liver transplant or suffer from liver disease. The study was published in the journal Oncotarget.
Researchers at the Mechanobiology Institute (MBI) at the National University of Singapore have discovered that the inherent ‘handedness’ of molecular structures directs the behaviour of individual cells and confers them the ability to sense the difference between left and right. This is a significant step forward in the understanding of cellular biology.
Research has discovered a role for prolactin, the hormone that stimulates milk production in nursing mothers, in the bond between parents. The study on cotton-top tamarins found a link between prolactin levels and sexual activity and cuddling among paired adults. Although this was a first for prolactin, it has previously been found for oxytocin, a hormone that stimulates childbirth and is linked to a range of pleasurable emotions.
Yale researchers have uncovered new details about the relationship between two proteins associated with the formation of cerebral cavernous malformations, a little understood neurovascular disorder.
An international team of more than 18 research groups has demonstrated that the compounds they developed can safely prevent harmful protein aggregation in preliminary tests using animals. The findings raise hope that a new class of drugs may be on the horizon for the more than 30 diseases and conditions that involve protein aggregation, including diabetes, cancer, spinal cord injury, Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis (ALS).
The motion of coins in a “Penny Pusher” carnival game is similar to the movement of cells in the eye’s lens, as described in a new study published in Investigative Ophthalmology & Visual Science (IOVS). This new insight may help scientists understand how the eye maintains its precise shape — critical for clear vision — and how cataracts develop.
A certain class of proteins has challenged researchers’ conventional notion that proteins have a static and well-defined structure.
Researchers at the University of California, San Diego School of Medicine have discovered a control switch for the unfolded protein response (UPR), a cellular stress relief mechanism drawing major scientific interest because of its role in cancer, diabetes, inflammatory disorders and several neural degenerative disorders, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS).
Dartmouth bioengineers demonstrate a novel system that couples nano-engineered particles and microfluidic chips for capturing and manipulating circulating tumor cells.
An experimental drug that attacks brain tumor tissue by crippling the cells' energy source called the mitochondria has passed early tests in animal models and human tissue cultures, say Houston Methodist scientists.
Investigators from Dartmouth's Norris Cotton Cancer Center find that the protein Pom1 possesses the ability to modify different sets of proteins to coordinate the processes of cell growth and division.
Tumors that produce more stress granules are more likely to metastasize, according to researchers in Canada. The results suggest that drugs to inhibit the formation of these structures might rein in cancer metastasis.
Scientists at Albert Einstein College of Medicine have developed a fluorescence microscopy technique that for the first time shows where and when proteins are produced. This allows researchers to directly observe individual mRNAs as they are translated into proteins in living cells. It should help reveal how irregularities in protein synthesis contribute to human disease processes, including Alzheimer’s disease and other memory-related disorders. The research publishes in the March 20 edition of Science.
Working with lab animals and human heart cells, scientists from Johns Hopkins and other institutions have identified what they describe as “the long-sought culprit” in the mystery behind a cell-signaling breakdown that triggers heart failure.
Researchers figure out a way to isolate and grow thousands elusive intestinal stem cells at one time, a high throughput technological advance that could give scientists the ability to study stem cell biology gastrointestinal disorders like never before.
To pack two meters of DNA into a microscopic cell, the string of genetic information must be wound extremely carefully into chromosomes. Surprisingly the DNA’s sequence causes it to be coiled and uncoiled much like a yoyo, scientists reported in Cell.
University of Utah biologists report how a disposable molecular ruler or tape measure determines the length of needles bacteria use to infect cells. The findings have potential applications for new antibiotics and anticancer drugs and for helping people how to design nanomachines.
Scientists from the Florida campus of The Scripps Research Institute have confirmed the ribosome assembly process as a potentially fertile new target for anti-cancer drugs by detailing the essential function of a key component in the assembly process.
Three years after discovering that a single, unidentified mechanism was modifying about 800 proteins simultaneously during cell division, Florida State University researchers have identified that mystery enzyme.
Researchers conducted a study that looked at how proteasome-specific chaperones work at the molecular level to help in proteasome formation. Fully understanding this process may present new target sites for drugs and may lead to better treatments for neurological diseases, cancers and other disorders.
Researchers reveal how cells protect themselves from a protein that is a key driver of cancer.
Scientists at Benaroya Research Institute at Virginia Mason (BRI) have made an unexpected discovery that overturns a longstanding belief in the biological sciences. The research demonstrates that chitin, a molecule that was previously thought to be absent in vertebrates and that has been shown to trigger an allergy/immune reaction in mammals, is endogenously produced in fishes and amphibians.
Scientists have created a 3-D model of a complex protein machine, ORC, which helps prepare DNA to be duplicated. Like an image of a criminal suspect, the intricate model of ORC has helped build a “profile” of the activities of this crucial “protein of interest.” But the new information has uncovered another mystery: ORC’s structure reveals that it is not always “on” as was previously thought, and no one knows how it turns on and off.
A unique X-ray laser innovation developed at the Department of Energy's SLAC National Accelerator Laboratory may make it easier and faster for scientists to fully map medically important proteins whose structures have remained stubbornly out of reach.
Researchers at Johns Hopkins have successfully corrected a genetic error in stem cells from patients with sickle cell disease, and then used those cells to grow mature red blood cells, they report. The study represents an important step toward more effectively treating certain patients with sickle cell disease who need frequent blood transfusions and currently have few options.
New research from The Scripps Research Institute shows that two proteins critical for maintaining healthy day-night cycles also protect against mutations that could lead to cancer.
Salk scientists re-engineered the bacterial defense system CRISPR to recognize HIV inside human cells and destroy the virus, offering a potential new therapy.
A team led by scientists at The Scripps Research Institute has determined the basic structural organization of a molecular motor that hauls cargoes and performs other critical functions within cells.
Chemists at The Scripps Research Institute (TSRI) have developed a broadly useful technique for building new drug molecules and other chemical products.
Scientists at The University of Texas MD Anderson Cancer Center have discovered new information about a key pathway known as Hippo, a metaphoric name referencing its link to tissue “overgrowth.” The Hippo pathway has been shown to regulate cell death and cell growth, thus playing a role in the development or prevention of tumors.
The popular dietary supplement ubiquinone, also known as Coenzyme Q10, is widely believed to function as an antioxidant, protecting cells against damage from free radicals. But a new study by scientists at McGill University finds that ubiquinone is not a crucial antioxidant.
A new sequencing technique may provide a clearer picture of how genes in mitochondria, the “powerhouses” that turn sugar into energy in human cells.
Researchers at Vanderbilt University and in Germany have found that sodium – salt – accumulates in the skin and tissue in humans and mice to help control infection.
Cells control the adhesion protein desmoplakin by modifying the tail end of the protein, and this process goes awry in some patients with arrhythmogenic cardiomyopathy, according to a new study.
Researchers show that toning down the activity of the receptor TREM2 may help put a stop to neurodegeneration in Alzheimer's disease.
A protein that helps embryonic stem cells retain their identity also promotes DNA repair. The findings raise the possibility that the protein, Sall4, performs a similar role in cancer cells, helping them survive chemotherapy.
With the aid of X-ray crystallography, researchers at the University of Michigan have revealed the structures of two closely related enzymes that play essential roles in the body's ability to metabolize excess lipids, including cholesterol.
Scientists have captured the first detailed microscopy images of ultra-small bacteria that are believed to be about as small as life can get. The research was led by scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory and the University of California, Berkeley. The existence of ultra-small bacteria has been debated for two decades, but there hasn’t been a comprehensive electron microscopy and DNA-based description of the microbes until now.
Scientists at NYU Langone Medical Center and New York University have demonstrated that a specialized DNA-binding protein called CTCF is essential for the precise expression of genes that control the body plan of a developing embryo.
Targeting mechanisms in the central nervous system that sense energy generated by nutrients might yield the beneficial effects of low-calorie diets on healthy aging without the need to alter food intake, suggests new research from Harvard T.H. Chan School of Public Health.
A new study led by researchers at The Scripps Research Institute (TSRI) and the University of California (UC), San Diego School of Medicine shows that certain stem cell culture methods are associated with increased DNA mutations.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right