Skin cancer is the most common form of cancer in the United States, with one in five Americans developing it over the course of their lives.
Research from Rutgers Cancer Institute of New Jersey and Rutgers School of Public Health shows more than a third of New Jersey high school students who engage in indoor tanning do so frequently and many would find it hard to stop the practice. Investigators also found that frequent indoor tanners were more likely to smoke and to engage in social media activities related to indoor tanning.
Once again, researchers at Penn’s Abramson Cancer Center have extended the reach of the immune system in the fight against metastatic melanoma, this time by combining the checkpoint inhibitor tremelimumab with an anti-CD40 monoclonal antibody drug.
If you have a cold sore – small blisters on the lip or around the mouth – you’re not alone. More than half of Americans ages 14 to 49 carry the virus that causes cold sores. The virus stays in the body even after the cold sores clear. If the virus reactivates, or wakes up, you could get cold sores.
A UNC Lineberger-led study found that people with higher-risk melanoma containing either BRAF or NRAS gene mutations had lower survival rates.
A new study finds that the incidence of pediatric melanoma in the United States decreased from 2004 to 2010.
"Tanning beds cause skin cancer. It is time to now more openly announce this causality," says Robert P. Dellavalle, MD, PhD, MSPH, investigator at the CU Cancer Center, in the American Journal of Preventive Medicine.
The significance of this work is its descriptions of alternative mechanisms by which tumors move and settle in new locations.
Personalized melanoma vaccines can be used to marshal a powerful immune response against unique mutations in patients' tumors, according to early data in a first-in-people clinical trial at Washington University School of Medicine in St. Louis. The research is reported April 2 in Science Express.
Spreading the success of cancer immunotherapy beyond those patients currently enjoying powerful, long-term responses to treatment requires greater understanding of the immune response to tumors, two leaders in the field note in a review in the April 3 Science.
Researchers at the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences produced 3D maps of molecular and microbial variations across the body. These maps provide a baseline for studies of the interplay between the molecules that make up our skin, our microbiomes, our personal hygiene routines and other environmental factors. The study, published March 30 by PNAS, may help further our understanding of the skin’s role in human health and disease.
An experimental therapy developed by researchers at Albert Einstein College of Medicine of Yeshiva University cut in half the time it takes to heal wounds compared to no treatment at all. Details of the therapy, which was successfully tested in mice, were published online in the Journal of Investigative Dermatology.
There are nearly 10,000 melanoma deaths in the U.S. each year, and while treatment advances have been made, a majority of melanoma patients will die from their disease. Building on these advances, Rutgers Cancer Institute of New Jersey investigators have demonstrated that removal of a gene involved in the cellular self-cannibalization process of autophagy could provide therapeutic benefit to patients with melanoma.
Sunbathers could soon tell when to take shelter in the shade thanks to an early warning sunburn indicator, developed by Queen’s University Belfast.
Medicine obviously can’t do much good if it sits on a pharmacy shelf. Yet more than one-quarter of the acne patients surveyed by Wake Forest Baptist Medical Center researchers didn’t get medications prescribed by their dermatologists.
Every sport is different, and every athlete has unique needs. No matter their game, though, athletes across the board are prone to five dermatologic issues: blisters, turf burns, athlete’s foot, acne mechanica and exposure to ultraviolet (UV) light. Fortunately, there are ways to prevent these problems and treat them when they occur.
Within the last five years, targeted therapy and immunotherapy have emerged as viable treatment options for patients with advanced melanoma. Although these therapies have promising implications, early detection still gives patients the best chance of survival.
Among the new research presented at the American Academy of Dermatology’s 73rd Annual Meeting are two studies examining skin cancer risk in minority populations. One investigation found that gay and bisexual men are more likely to use indoor tanning devices and develop skin cancer than straight men, while another found that Hispanic and Asian women have an increased risk of developing nonmelanoma skin cancer.
Vitiligo affects the skin, but it’s not just skin deep. This condition can be detrimental to patients’ emotional health, and a recent study indicates that it also may have implications for their physical health. According to research presented at the American Academy of Dermatology’s 73rd Annual Meeting in San Francisco, certain autoimmune diseases, including thyroid disease and alopecia areata, may be more prevalent among vitiligo patients.
Exfoliation can improve your skin’s appearance and make topical treatments more effective, but every type of exfoliation may not work for every skin type. In fact, some exfoliation treatments may actually make some people’s skin worse. A board-certified dermatologist can help individuals understand their skin and choose the exfoliation option that’s best for them.
In the last several years, targeted therapies – drugs that directly impact specific genes and proteins involved in the progression of cancer – have been approved for a wide variety of cancers, including melanoma, the deadliest form of skin cancer. Now, researchers at The Wistar Institute have discovered one way in which melanoma becomes resistant to a particular form of targeted therapy, and understanding this phenomenon may lead to a new melanoma target or prompt new designs of these treatments.
Today marked the publication of the first ever genome-wide association study of rosacea, a common and incurable skin disorder. Led by Dr. Anne Lynn S. Chang of Stanford University’s School of Medicine, and co-authored by 23andMe, the study is the first to identify genetic factors for this condition.
If you have ever had chickenpox, or been vaccinated for it, you are at risk for getting shingles – a painful, blistering rash. This is because after the chickenpox clears, the virus stays in the body. If the virus reactivates, or wakes up, you could get shingles.
The St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project found that melanoma in some adolescent and adult patients involves many of the same genetic alterations and would likely respond to the same therapy. The research appears in the March issue of the Journal of Investigational Dermatology.
Researchers find that melanoma cells are dependent on a source of glutamine for growth irrespective of the mutation(s) that drive the cancer.
Melanoma, the most deadly type of skin cancer, was to blame for approximately 9,700 deaths in 2014. And with the number of melanoma cases increasing each year, it is believed that the disease could become one of the most common types of cancer in the United States by 2030. Promoting and developing national screening strategies may help to reduce deaths due to melanoma. According to Vernon K. Sondak, M.D., chair of the Department of Cutaneous Oncology at Moffitt Cancer Center, “it is time to embrace the opportunity to decrease melanoma mortality through risk-stratified education and screening.”
In what is believed to be the largest epigenetic analysis to date of cell-signaling molecules in early-stage melanoma, researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center have identified two tiny bits of non-coding genetic material in primary tumors that appear critical to stalling the cancer’s spread -- and essentially setting the biological fate of the disease.
Despite advances in melanoma treatment, many patients with advanced melanoma will need several lines of therapy according to a recent paper in Current Opinion in Oncology.
Do you have a favorite black sweater, but you’re afraid to wear it because of dandruff? Fear not, say dermatologists from the American Academy of Dermatology (Academy). Although those pesky white flakes of dry skin can be annoying, especially if you’re wearing dark colors, it’s fairly easy to treat and control dandruff with patience – and the right dandruff shampoo.
The American Academy of Dermatology Association offers its thanks to FDA Commissioner Hamburg
Popularized by celebrities and featured in news segments, unique – sometimes offbeat – beauty treatments promise the fountain of youth. While some initial research studies have shown these fad treatments to be effective, dermatologists remain cautious about recommending them over proven therapies, which have been more extensively studied and can provide longer-lasting results.
Eating healthier is a common recommendation for people looking to reduce their risk of heart disease, cancer, diabetes and other medical concerns. Now a growing body of research is evaluating whether certain dietary changes can impact the skin by reducing the signs of aging and improving some skin conditions. Nutricosmetics – the use of nutrition or nutritional supplements for skin health and beauty – is popular abroad and may be the next frontier for improving skin health and beauty in the United States.
While complete scar removal is not possible, dermatologists are harnessing a laser technology originally developed as an anti-aging treatment to improve the appearance of scars – especially hard-to-treat or older ones. This new treatment option is bringing renewed self-confidence to patients, helping to ease traumatic memories, and in some cases, increasing lost mobility.
Nada Elbuluk, MD, MSc, from the Ronald O. Perelman Department of Dermatology at NYU Langone Medical Center, offers practical advice and treatment options for dealing with ingrown hair, also known as "razor bumps."
This feature provides tips from physicians on how those interested in getting a tattoo can protect themselves from also getting an unwanted disease during the tattoo process.
Winter months often bring in cold, harsh changes for skin and hair, but a few good habits can alleviate dryness as well as the discomfort of itchy skin. UT Southwestern dermatologists offer some insight on the role moisture plays, and how to keep your skin and hair healthy when the temperatures drop.
Case Western Reserve scientists have taken a leap toward identifying root causes of psoriasis. Of the roughly 50,000 proteins in the human body, researchers have zeroed in on four likely contributors to this inflammatory skin condition. The findings were published Molecular & Cellular Proteomics.
When the temperature dips below freezing, it’s critical to protect your skin from cold-weather health risks. Frostbite occurs when the skin – and sometimes the tissue beneath the skin – freezes due to prolonged exposure to cold temperatures. Depending on how long and how frozen the tissue, frostbite can result in severe, sometimes permanent, damage.
Researchers have discovered a way to repurpose fibroblasts into functional melanocytes, the body's pigment-producing cells. The technique has immediate and important implications for developing new cell-based treatments for skin diseases such as vitiligo, as well as new screening strategies for melanoma.
Everyone wants a happy, healthy baby, however, babies often experience discomfort from diaper rash. Help your baby by following dermatologists’ tips to prevent and treat diaper rash at home.
Clinical trials have shown that a preparation of rose bengal called PV-10 has induced regression of both injected lesions and uninjected bystander lesions in patients with melanoma, and tumor ablation with PV-10 has been shown to increase certain T-cell populations in patients' peripheral blood.
The stress of the holidays, poor nutrition and the cold weather can take its toll on nail health, according to Loyola University Health System dermatologist Rebecca Tung, MD.
A University of Colorado Cancer Center study published online this week in the journal Molecular Cancer Therapeutics reports anti-cancer activity in 10 out of 11 patient tumor samples grown in mice and treated with the experimental drug TAK-733, a small molecule inhibitor of MEK1/2.
UT Southwestern Medical Center researchers have determined the specific type of cell that gives rise to large, disfiguring tumors called plexiform neurofibromas, a finding that could lead to new therapies for preventing growth of these tumors.
Studies have demonstrated that exposure to ultraviolet (UV) radiation from the sun and indoor tanning damages the DNA in our skin cells. This not only increases a person’s risk for skin cancer, it can also lead to premature skin aging in the form of wrinkles and sun spots. November is National Healthy Skin Month – the perfect time to learn how to maintain healthy skin care habits.
The most obvious effects of too much sun exposure are cosmetic, like wrinkled and rough skin. Some damage, however, goes deeper—ultraviolet light can damage DNA and cause proteins in the body to break down into smaller, sometimes harmful pieces that may also damage DNA, increasing the risk of skin cancer and cataracts. Understanding the specific pathways by which this degradation occurs is an important step in developing protective mechanisms against it.
Study highlights need to monitor disease in developing countries even when burden of diseases is low.
Patients with more severe psoriasis are also more likely to have uncontrolled hypertension, according to new research by a team at the Perelman School of Medicine at the University of Pennsylvania. Through a cross-sectional study using information collected from a medical records database, the results provide further evidence of a strong link between psoriasis and hypertension. Full results are now available in JAMA Dermatology.
In rare cases, patients with allergies to metals develop persistent skin rashes after metal devices are implanted near the skin. New research suggests these patients may be at increased risk of an unusual and aggressive form of skin cancer.
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