Feature Channels: Infectious Diseases

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Released: 23-Nov-2015 3:05 PM EST
Expensive Drugs That Cure Hepatitis C Are Worth the Cost, Even at Early Stages of Liver Fibrosis
University of California, San Francisco (UCSF)

It is worthwhile to give patients expensive new drugs that can cure their hepatitis C much earlier than some insurers are now willing to pay for them, according to a UC San Francisco study that models the effects of treating the disease early versus late in its development.

Released: 23-Nov-2015 9:05 AM EST
Vitamin D Does Not Reduce Colds in Asthma Patients
American Thoracic Society (ATS)

Vitamin D supplements do not reduce the number or severity of colds in asthma patients, according to a new study published online ahead of print publication in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine

19-Nov-2015 8:05 AM EST
The Complex Sneeze, Caught on Tape
American Physical Society's Division of Fluid Dynamics

However commonplace it may be in human life, the sneeze remains somewhat of an enigma to science, and we are still a long way from understanding the simple sneeze in all its phlegm-flam glory. This month during APS’s DFD 2015 Meeting, researchers will present new work that shows how droplets are formed within a high-propulsion sneeze cloud -- a critical piece of the puzzle that has so far been missing.

Released: 19-Nov-2015 5:05 PM EST
Researchers Investigate Dengue Virus Transmission
New Mexico State University (NMSU)

Certain strains of dengue virus, the agent of dengue fever, can progress into a severe infection called dengue hemorrhagic fever, killing about 5 percent of the people who develop it. To further research into dengue virus transmission, New Mexico State University received $400,000 from the NIH.

Released: 19-Nov-2015 1:05 PM EST
STD's in America at an All-Time High - Experts Needed
Newswise Trends

According to a report by the U.S. Centers for Disease Control and Prevention, rates of sexually transmitted diseases like chlamydia, gonorrhea and syphilis climbed considerably in the U.S. in 2014. The center called the increases "alarming." The new data also show that among the more than 3,000 counties in the nation, Los Angeles County had the most cases of all three diseases in 2014.

Released: 18-Nov-2015 4:05 PM EST
Hepatitis C Treatment Made Easy
RUSH

Study results just published in the New England Journal of Medicine have found that a new drug combination may simplify hepatitis C treatment for both patients and physicians.

17-Nov-2015 12:00 PM EST
Study in Mice Suggests Coconut Oil Can Control Overgrowth of a Fungal Pathogen in GI Tract
Tufts University

A new study from researchers at Tufts University found that coconut oil controlled the overgrowth of a fungal pathogen called Candida albicans in mice. In humans, high levels of C. albicans in the gastrointestinal tract can lead to bloodstream infections, including invasive candidiasis. The research suggests that it might be possible to use dietary approaches as an alternative to antifungal drugs in order to decrease the risk of infections caused by C. albicans.

Released: 17-Nov-2015 4:05 PM EST
Chagas Disease, a Deadly Bug-Borne Infection, Is Spreading in Texas
Newswise Trends

Chagas Disease, all a deadly bug-borne infection, Is spreading in Texas. Chagas is transmitted via the "kissing bug."

Released: 17-Nov-2015 12:05 PM EST
Vitamin D Deficiency May Limit Immune Recovery in HIV-Positive Adults
University of Georgia

A University of Georgia researcher has found that low levels of vitamin D may limit the effectiveness of HIV treatment in adults.

16-Nov-2015 12:00 PM EST
TSRI Scientists Find Surprising Trait in Anti-HIV Antibodies
Scripps Research Institute

Scientists at The Scripps Research Institute (TSRI) have new weapons in the fight against HIV. Their new study describes four prototype antibodies that target a specific weak spot on the virus.

Released: 17-Nov-2015 11:05 AM EST
Scripps Florida Scientists Discover New Compounds with Potential to Treat Persistent Tuberculosis
Scripps Research Institute

In a substantial number of cases—some two billion, in fact—the tuberculosis bacteria (Mycobacterium tuberculosis) isn’t active at all. Now, scientists from the Florida campus of The Scripps Research Institute (TSRI) have discovered several first-in-class compounds that target these hidden infections.

   
16-Nov-2015 4:05 PM EST
For Kids Prone to Wheezing with Respiratory Infections, Early Antibiotics Help​
Washington University in St. Louis

In children whose colds tend to progress and lead to severe wheezing and difficulty breathing — such that they are given oral corticosteroids as rescue therapy — researchers have shown that giving a common antibiotic at the first sign of cold symptoms can reduce the risk of the episode developing into a severe lower respiratory tract illness. The new study, led by researchers at Washington University School of Medicine in St. Louis, appears online Nov. 17 in JAMA.

Released: 16-Nov-2015 4:05 PM EST
Simple Drug Regimen Cures Hepatitis C Virus in Patients After 12 Weeks
University Health Network (UHN)

Researchers at the Toronto Western Hospital (TWH) Liver Clinic have found that a simple drug regimen delivered over 1​2 weeks achieved sustained eradication of several genotypes of the hepatitis C virus (HCV) in 99 per cent of the trial's patients.

11-Nov-2015 6:05 AM EST
Thrombosis During Sepsis Is a Consequence of Protective Host Immune Responses
University of Birmingham

Researchers from the University of Birmingham have, for the first time, identified how Salmonella infections that have spread to our blood and organs can lead to life-threatening thrombosis.

13-Nov-2015 6:05 PM EST
Study Sheds Light on Why Parasite Makes TB Infections Worse
Washington University in St. Louis

Scientists have shown how a parasitic worm infection common in the developing world increases susceptibility to tuberculosis. The study raises the possibility of using inexpensive and widely available anti-parasitic drugs as a preventive measure in places where the parasite and TB are common — stopping infection with the parasite and reducing susceptibility to TB and the risk of a latent TB infection progressing to disease.

Released: 16-Nov-2015 11:05 AM EST
Stony Brook Children’s Hospital Expert Shares Tips with Parents on When to Use Antibiotics and When At-Home Remedies May Do the Trick
Stony Brook Medicine

The CDC’s Get Smart campaign involves a number of initiatives to prevent antibiotic resistance, manage existing antibiotics to preserve their effectiveness and help healthcare providers and families understand when prescribing an antibiotic is appropriate — and when it is not.

Released: 16-Nov-2015 10:05 AM EST
Responding To "C-diff"—Concerted Action Needed to Control Health Care-Related Infection
Wolters Kluwer Health: Lippincott

Appropriate use of antibiotics is a critical step toward controlling the ongoing epidemic of health care-related Clostridium difficile infection (CDI), according to a special article in the November issue of Infectious Diseases in Clinical Practice. The journal, affiliated with the National Foundation for Infectious Diseases (NFID), the journal is published by Wolters Kluwer.

10-Nov-2015 3:35 PM EST
Child with Drug-Resistant TB Successfully Treated at Johns Hopkins Children's Center
Johns Hopkins Medicine

Johns Hopkins Children’s Center specialists report they have successfully treated and put in remission a 2-year-old, now age 5, with a highly virulent form of tuberculosis known as XDR TB, or extensively drug-resistant TB.

Released: 11-Nov-2015 4:05 PM EST
Study Finds Sexually Transmitted Infection Affecting Up to 1% of the Population Aged 16-44 in the UK
Oxford University Press

A new study strengthens growing evidence that Mycoplasma genitalium (MG) is a sexually transmitted infection (STI). The findings are recently published in the International Journal of Epidemiology.

Released: 11-Nov-2015 4:05 PM EST
Study Offers New Recommendations for TB Vaccine Testing in Humans
Colorado State University

CSU Professor Ian Orme recently conducted a study that provides new clues to what went wrong with a landmark TB vaccine trial in South Africa.

10-Nov-2015 9:00 AM EST
New Research Raises Questions About Using Certain Antibiotics to Treat “Superbug” MRSA
Cedars-Sinai

New Research in Cell Host & Microbe Indicates Commonly Prescribed Antibiotic Could Potentially Worsen Methicillin-Resistant Staphylococcus Aureus

Released: 10-Nov-2015 4:05 PM EST
Researchers Find Some Surprising Results Testing Mosquito Repellents
New Mexico State University (NMSU)

If you want to keep away blood-sucking insects, DEET products are your best bet according to a recent study from New Mexico State University. Researchers also discovered a certain perfume performed better at protecting against mosquitoes than some commercial insect repellents.

9-Nov-2015 5:05 AM EST
Using Copper to Prevent the Spread of Respiratory Viruses
University of Southampton

New research from the University of Southampton has found that copper can effectively help to prevent the spread of respiratory viruses, which are linked to severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS).

Released: 10-Nov-2015 9:05 AM EST
Research Points to Development of Single Vaccine for Chikungunya, Related Viruses
Washington University in St. Louis

What if a single vaccine could protect people from infection by many different viruses? That concept is a step closer to reality. Researchers at Washington University School of Medicine​ in St. Louis have identified “broadly neutralizing” antibodies that protect against infection by multiple, distantly related alphaviruses – including Chikungunya virus – that cause fever and debilitating joint pain. The discovery, in mice, lays the groundwork for a single vaccine or antibody-based treatment against many different alphaviruses.

Released: 9-Nov-2015 1:05 PM EST
Surgical Site Infections Decrease 100% After Trinity Medical Center Implements Infection Control Bundle with Xenex Germ-zapping Robots for Room Disinfection
Xenex Disinfection Services

/PRNewswire/ -- Surgical Site Infections (SSIs) are devastating for patients and pose a significant financial risk for hospitals. Surgical Site Infections resulting from total knee or hip procedures cause excruciating pain and suffering, have a three percent mortality rate and are associated with an additional $21,000 in additional care costs per infection. As hospitals worldwide struggle to prevent infections, Alabama-based Trinity Medical Center experienced a 100 percent decrease in Surgical Site Infection rates in its orthopedic Operating Rooms (ORs) after implementing a total joint infection control bundle that includes Xenex Germ-Zapping Robots™ to disinfect its ORs and patient rooms.

Released: 6-Nov-2015 1:05 PM EST
New Look at PrEP Study Points to Efficacy for Transgender Women
University of California, San Francisco (UCSF)

In a new look at the groundbreaking iPrEx trial for people at high risk of HIV infection, UCSF researchers have identified strong evidence of efficacy for transgender women when PrEP, a two-drug antiretroviral used to prevent HIV, is used consistently.

Released: 6-Nov-2015 10:05 AM EST
UGA Researchers Identify Essential Component of Antiviral Defense
University of Georgia

Infectious disease researchers at the University of Georgia have identified a signaling protein critical for host defense against influenza infection. The findings shed light on how a single component of the body’s defense system promotes effective immunity against viral infections—particularly respiratory viruses—that affect mucosal sites.

2-Nov-2015 9:05 AM EST
Vaccine Against Respiratory Syncytial Virus (RSV) Shows Promise in Early Trial
Johns Hopkins Bloomberg School of Public Health

Johns Hopkins Bloomberg School of Public Health researchers say a new candidate vaccine against respiratory syncytial virus (RSV) made with a weakened version of the virus shows great promise at fighting the disease, the leading cause of hospitalization for children under the age of one in the U.S.

Released: 4-Nov-2015 11:05 AM EST
Bat Disease Fungus Found to Be Widespread in Northeast China
University of California, Santa Cruz

Discovery greatly expands the known distribution of the fungus that causes white-nose syndrome, which has decimated bat populations in North America

28-Oct-2015 12:00 PM EDT
Forgotten but Not Gone: West Nile Virus Impacts Greater Number of Bird Species, Study Finds
Colorado State University

A new study led by Colorado State University finds that the West Nile virus is killing birds — more so than previously thought — in the short- and long-term.

Released: 2-Nov-2015 9:05 AM EST
Maglab Research Paves Way for Flu Treatments
Florida State University

Led by Professor of Chemistry & Biochemistry Tim Cross and his team at the Florida State University-based National High Magnetic Field Laboratory, scientists delved into the complexities of exactly how the flu virus works and why it’s so effective at making people so sick. With a better understanding of how it works, researchers will now be able to turn their attention to creating more effective prescription drugs to fight the flu.

Released: 2-Nov-2015 7:05 AM EST
DNA Sequencing Shows Divergent Genomes in Malaria Vectors of Brazilian Rainforest
St. Mary's College of Maryland

A new study by Kevin J. Emerson, PhD, assistant professor of biology at St. Mary’s College of Maryland and his international group of collaborators assessed the extent to which geographical barriers affected genetic variation among Anopheles darlingi populations. Such barriers may greatly influence the approaches used by scientists and physicians to control the spread of malaria throughout Brazil.

Released: 30-Oct-2015 9:05 AM EDT
New Immunotherapy Treatment May Clear Cancer-Causing HPV Infections Faster
University of Louisville

A new therapeutic vaccine, GTL001, developed by Genticel to clear HPV strains 16 and 18 – the types most likely to cause cancer – is being evaluated for safety in a Phase I clinical trial at the University of Louisville, along with Philadelphia and Columbus, Oh.

Released: 29-Oct-2015 11:45 AM EDT
HIV/AIDS Deaths Are Down in South Africa—But Most Are Still Unacknowledged
Wolters Kluwer Health: Lippincott

After peaking in 2007, AIDS mortality in South Africa has decreased with the widespread introduction of effective antiretroviral therapy, according to updated estimates published in AIDS, official journal of the International AIDS Society. AIDS is published by Wolters Kluwer.

Released: 28-Oct-2015 4:05 PM EDT
$5.8 Million NIH Contract to Saint Louis University to Fund ‘Omics’ Research
Saint Louis University Medical Center

Saint Louis University’s Vaccine Center is one of two sites in the nation selected by the NIH to conduct "omics" research on infectious diseases.

Released: 28-Oct-2015 11:05 AM EDT
Statement from American Thoracic Society Past President and TB Expert Dean Schraufnagel on WHO Report on TB
American Thoracic Society (ATS)

The American Thoracic Society applauds the World Health Organization (WHO) on today’s release of its Global Tuberculosis Report 2015, which finds that the number of TB deaths is now virtually equal to the number of HIV/AIDS deaths globally. The data shows that TB threatens to undo the tremendous progress made by the President's Emergency Plan for AIDS Relief (PEPFAR) and the Global Fund Against AIDS, TB and Malaria. The ATS joins the WHO in calling for increased funding to halt the global TB pandemic.

Released: 27-Oct-2015 6:30 AM EDT
Clorox Launches Cold & Flu Pulse: A Socially Predictive Cold & Flu Tracker
Clorox Company

The Clorox Cold & Flu Pulse analyzes millions of conversations in real time and reports how cold and flu is trending online, including what topics are being discussed, top cities where it’s trending, and tips related to the current virality of the cold and flu.

Released: 26-Oct-2015 7:05 PM EDT
Natural Immunity May Lead Fight Against Liver Disease
University of Adelaide

University of Adelaide researchers have uncovered the role played by a family of genes, which can suppress hepatitis C virus (HCV) infection within the liver.

Released: 26-Oct-2015 5:05 PM EDT
A Notable Honor for Ebola Response Team as It Planned and Prepared for the Ebola Virus
MedStar Washington Hospital Center

MedStar Washington Hospital Center’s Ebola Response Team has been honored with the 2015 Patient Safety Award from the District of Columbia Hospital Association (DCHA). The award recognizes the team’s outstanding efforts in its Ebola-related plans and training to care for potential or confirmed patients with the Ebola virus.

Released: 26-Oct-2015 4:40 PM EDT
Better Organized HIV Care Could Save Lives and Billions of Dollars, Computer Model Predicts
Johns Hopkins Medicine

A computer model developed by Johns Hopkins health care delivery specialists predicts that strengthening a handful of efforts to keep people with HIV in lifetime care, along with more rigorous testing, would potentially avert a projected 752,000 new HIV infections and 276,000 AIDS deaths in the United States alone over the next 20 years.

19-Oct-2015 10:00 AM EDT
Patients More Engaged in Their Anesthesia, Pain Relief Options When Given ‘Decision Aids’ or Brochures
American Society of Anesthesiologists (ASA)

“Decision aids” in the form of informational brochures help get patients talking about their anesthesia and pain relief options, according to a study presented at the ANESTHESIOLOGY® 2015 annual meeting. Shared decision making is critical to a more patient-centered process, as well as helping patients take an active role in their medical decisions.

14-Oct-2015 4:05 PM EDT
Scientists Discover Ancient Safety Valve Linking Pollen to Bacteria
Washington University in St. Louis

New research shows that an ancient protein that protects bacteria from bursting also helps pollen survive the dangerous transition from desiccated to hydrated once it lands on the female flower. But in pollen’s case, the protein has evolved to provide just the right amount of internal pressure: enough to power cell growth but not so much that the pollen bursts and dies.

Released: 22-Oct-2015 3:05 PM EDT
A DNA Study Shows That the Bubonic Plague Has Infected Humans Since the Bronze Age
Newswise Trends

According to a report from the Centers for Disease Control and Prevention, a total of 11 cases have been reported in the United States since April 1st, 2015.

15-Oct-2015 12:05 PM EDT
Could a Drug Engineered From Bananas Fight Many Deadly Viruses? New Results Show Promise
Michigan Medicine - University of Michigan

A banana a day may not keep the doctor away, but a substance originally found in bananas and carefully edited by scientists could someday fight off a wide range of viruses. And the process used to create it may help scientists harness the “sugar code” that our cells use to communicate.

Released: 21-Oct-2015 3:05 PM EDT
Findings on Immune Response Inform Direction of HIV Vaccine Development
Fred Hutchinson Cancer Center

Analyses of landmark RV144 HIV vaccine study volunteers revealed that those who developed a unique set of vaccine-induced antibodies in combination with a high level of CD4 T-cell responses to the outer portion of the HIV virus, called its envelope gene, correlated with reduced HIV infection.

Released: 21-Oct-2015 10:05 AM EDT
Staphylococcus aureus Achilles’ Heel
Université de Genève (University of Geneva)

Staphylococcus aureus is a formidable human pathogen. One of the bacterium’s most impressive weapons is α-toxin, which provokes the destruction of human cells. An international project allowed to identify the components of our cells that modulate the virulence of this toxin, in particular the PLEKHA7 protein.

Released: 20-Oct-2015 4:05 PM EDT
Studies Reveal a Unified Approach to Combating Several Bacterial Diseases
Argonne National Laboratory

Researchers at the University of Texas, the University of Connecticut, and the U.S. Department of Energy's (DOE's) Argonne National Laboratory have discovered structural similarities among bacteria of various types that create the possibility of using similar approaches to fight the infections they cause.

Released: 20-Oct-2015 10:05 AM EDT
Superbug Infection Greatest Increase in Children Ages 1-5
RUSH

Children are becoming infected with the highly fatal antibiotic resistant bacteria CRE at a much higher rate than the recent past, according to a data analysis by researchers at Rush University Medical Center. The study was published in the Centers for Disease Control’s publication Emerging Infectious Diseases on Oct. 14.

14-Oct-2015 2:05 PM EDT
Monkey Model Discovery Could Spur CMV Vaccine Development
Duke Health

Researchers at Duke Medicine have discovered that rhesus monkeys can, in fact, transmit Cytomegalovirus (CMV) across the placenta to their unborn offspring. This finding, reported online October 19 in the Proceedings of the National Academy of Sciences, establishes the first primate model that researchers can use to study mother-to-fetus CMV infections and spur development of potential vaccine approaches.



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