• Compared with kidney transplant recipients who did not report a disability, recipients with a visual disability were at higher risk of organ failure and recipients with a walking disability were at higher risk of early death. • Results from the study will be presented at ASN Kidney Week 2018 October 23–October 28 at the San Diego Convention Center.
• In patients with type 2 diabetes at high risk for cardiovascular disease, targeting blood sugar to normal levels (HbA1c<6.0%) reduced the risk for macroalbuminuria (a high amount of protein excreted in the urine) over an average follow-up of 7.7 years, but it had no impact on more significant kidney outcomes such as serum creatinine doubling (a marker of worsening kidney function) or the need for dialysis or transplantation. • Targeting low blood pressures (<120mmHg) or the use of fenofibrate to lower cholesterol increased the risk for doubling of serum creatinine, although it had no impact on the need for dialysis or transplantation.
• Results from biopsies taken when kidneys were procured from donors were not reliable for determining whether the organs were suitable for transplantation.
Glyn R. Morgan, MD, MSc, FRCSC, FACS, one of the nation's leading liver and kidney transplant surgeons, has been named director of Loyola Medicine's division of intra-abdominal transplant.
The American Society of Nephrology’s Kidney Health Initiative is releasing its Technology Roadmap for Innovative Approaches to Renal Replacement Therapy.
Results of a phase II clinical trial show that novel drug sparsentan is an effective treatment for the rare kidney disease focal segmental glomerulosclerosis (FSGS), which currently has no FDA-approved therapies.
Mount Sinai nephrologists will be in attendance and available to comment on breaking news, in addition to their own research.
• Receiving high-dose vs. standard dose influenza vaccine in 2016-17 was associated with lower rates of hospitalization in dialysis patients, although this association was not seen in 2015-16 (when few dialysis patients received the high-dose vaccine). • There were no differences in rates of death between patients receiving the high-dose vs. standard dose influenza vaccine during either time period.
Using a novel biomarker panel to track and measure kidney function, researchers at University of California San Diego School of Medicine and University of California San Francisco School of Medicine report that lowering systolic blood pressure to less than 120 mm Hg does not damage the kidney organ itself. Instead, any negative changes to clinical results are more likely due to decreased blood flow.
American Society of Nephrology Kidney Week Press Briefing
Treatment of renal cell carcinoma with stereotactic radiation therapy is as safe and effective for patients with one kidney as it is for those who have two, according to an analysis of the largest-ever, international dataset of solitary kidney patients to receive this emerging treatment. Findings will be presented in a news briefing today at noon ET from the American Society for Radiation Oncology (ASTRO) Annual Meeting.
Five leaders in the kidney health community are being honored by the American Society of Nephrology (ASN), the world’s largest organization of kidney disease specialists.
The American Society of Nephrology (ASN), will bestow the President’s Medal to Griffin P. Rodgers, MD, MACP, for his leadership in kidney research and advocacy.
• Lower perceived quality of patient-physician interaction was associated with a higher risk of hospitalization in Hispanics with chronic kidney disease. • Quality of patient-physician interaction was not associated with risk of developing kidney failure or dying.
Researchers have developed a new test that could diagnose chronic kidney disease early in patients with type 2 diabetes. This novel method, published today in AACC’s Clinical Chemistry journal, could improve quality of life for diabetic patients by potentially catching chronic kidney disease in time to stop its progression to full-blown kidney failure.
UAB transplant surgeon Jayme Locke recently shared six steps to building a dream career. To be a surgeon, you have to have confidence. “I tend to be grandiose in my thinking,” said Jayme Locke, M.D., MPH, director of the University of Alabama at Birmingham’s Incompatible Kidney Transplant Program and vice chair for Health Services Research in the Department of Surgery.
According to a study recently published in the Journal of Cellular Physiology, even low, allowable levels of arsenic may be enough to cause kidney disease. The good news, however, is there may be a way to treat such kidney disease using a drug already approved by the FDA – just not for this purpose.
To further its mission of facilitating timely and broad dissemination of kidney science, the American Society of Nephrology (ASN) today announced an addition to its journal portfolio, Kidney360. The journal will available online monthly beginning January 2020.
• In a study of young adults with kidney failure, poor wellbeing and lower medication adherence were both associated with psychological morbidity. • Dialysis treatment (vs. kidney transplantation) was associated with poorer wellbeing and medication adherence.
In 2016, the ASN Foundation for Kidney Research launched the Securing the Future Campaign with the goal to endow the Career Development Grants Program. The campaign has since raised more than $22 million through generous contributions from industry, individual donors, and the American Society of Nephrology (ASN).
The American Society of Nephrology (ASN), the world’s largest organization of kidney health professionals, released a new report on the annual survey of nephrology fellows authored by George Washington University (GW) researchers.
Adult patients who received liver and kidney transplants at Rush University Medical Center had better-than-expected one-year survival rates, according to the most recent transplantation on the 5-tier system report by the Scientific Registry of Transplant Recipients (SRTR), which was released on Oct. 9.
• Certain parameters measured by ultrasound helped predict the success of an arteriovenous fistula, the preferred type of hemodialysis vascular access, in individual patients.
Description: Papers on carcinogenesis; organophosphate flame retardants and zebrafish behavior; AHR gene targeting and hepatotoxicity; nontoxic substructures; and genistein and type 1 diabetes featured in latest issue of Toxicological Sciences.
• In a multi-ethnic study of individuals without kidney disease, high blood levels of an inflammatory marker, sTNFR-1, were associated with greater kidney function decline over time. • This association was independent of previously known risk factors for kidney disease progression and persisted across multiple sub-groups of participants.
Penn Medicine experts in nephrology and health policy call for more transparency about joint-venture ownership of dialysis clinics to better understand what impact these arrangements may have on patient referrals and clinical outcomes. The lack of transparency poses a major barrier for evidence-based health care policy research and deprives patients of critical information, the researchers write in a new Perspective published in the New England Journal of Medicine.
By investigating how genetic variations drive the expression of genes within the filtering cells of the kidney, researchers have found new pathways to explain CKD development and could inform its treatment.
The American Society of Nephrology (ASN), the world’s largest organization of kidney health professionals, released a new analysis of early career nephrologists authored by George Washington University (GW) researchers. GW’s report details significant differences between nephrologists beginning their careers in group practices compared to those starting in academic positions. The report noted the differences between these two groups of nephrologists included income, hours worked, job satisfaction, and whether they would recommend the specialty. More than 40 million Americans have kidney diseases, the 9th leading cause of death in the U.S.
The American Thyroid Association (ATA) announces with pleasure that the 2018 John B. Stanbury Thyroid Pathophysiology Medal will be awarded to Dr. Marvin C. Gershengorn at the ATA Annual Meeting this week. Dr. Gershengorn is Chief of the Clinical Endocrinology Branch (formerly the Laboratory of Endocrinology and Receptor Biology) at the National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, Maryland.
Participants from Congress, HHS, NIH, and the kidney community discussed greater coordination among public and private institutions to increase innovation in kidney care and research
A commonly used biomarker of kidney disease may also indicate lung problems, particularly COPD, or chronic obstructive pulmonary disease, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
• Among patients with kidney failure on dialysis, use of proton pump inhibitors was associated with a 19% higher risk of hip fracture. The association remained within subgroups of low, moderate, and high use, yielding of 16%, 21%, and 19% greater risks, respectively. • Histamine-2 receptor antagonists were not associated with hip fracture events.
The prevalence of kidney diseases in the United States is at a record high. As such, members of “kidney community” healthcare groups, including the American Society of Nephrology (ASN), will meet with Congress on Capitol Hill to commend them for a $2 billion funding increase for the NIH with an at least proportional increase for the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), and advocate for increased innovation in kidney medicine, including the Kidney Innovation Accelerator (KidneyX), and passage of the Living Donor Protection Act of 2017 (H.R. 1270).
The lives of two healthcare caregivers changed in two different, dramatic ways, thanks to generous organ donation.
根据发表在《美国肾脏病学会临床杂志》（Clinical Journal of the American Society of Nephrology）上的一项Mayo Clinic的研究显示，接受手术切除卵巢的绝经前妇女患慢性肾病的风险会增加。
Jacqueline Chang, MD, a pulmonologist at Beth Israel Deaconess Medical Center, shares common triggers of Restless Leg Syndrome (RLS).
• Among children on dialysis for end-stage kidney failure, patients with vasculitis, ischemic kidney failure, and hemolytic uremic syndrome were most likely to regain kidney function and no longer need dialysis. • Younger age and initiation on hemodialysis instead of peritoneal dialysis were also associated with recovery of kidney function.
Scientists, clinicians, and other members of the international kidney health community will join forces in sunny southern California this October 23–28 for the American Society of Nephrology’s (ASN) Kidney Week 2018. Held in San Diego, this largest event of its kind offers a forum to share and hear advances in basic, clinical, and translational research, and to discover the latest innovations in clinical practice.
De acuerdo al estudio de Mayo Clinic publicado el miércoles 19 de septiembre en el Clinical Journal of the American Society de Nephrology, la extirpación quirúrgica de los ovarios durante la perimenopausia incrementa el riesgo de que las mujeres desarrollen insuficiencia renal crónica.
روتشستر، مينيسوتا - النساء اللواتي قمن بإستئصال المبيضين قبل انقطاع الطمث يواجهن خطر الإصابة بأمراض الكلى المزمنة بصورة متزايدة وفقًا للدراسات التي أجرتها Mayo Clinic وتم نشرها في Clinical Journal of the American Society of Nephrology.
Mulheres na pré-menopausa que passaram por uma cirurgia para remoção do ovário enfrentam um maior risco de desenvolver a doença renal crônica, segundo o estudo da Mayo Clinic publicado no Clinical Journal of the American Society of Nephrology.
ROCHESTER, Minn. — Premenopausal women who have their ovaries surgically removed face an increased risk of developing chronic kidney disease, according to a Mayo Clinic study published on Wednesday, Sept. 19, in the Clinical Journal of the American Society of Nephrology.
• On the 10th anniversary of the Renal Fellow Network (RFN), one of the first nephrology blogs, the American Society of Nephrology has created a partnership with RFN to continue its legacy and forge new opportunities.
In an analysis of all relevant studies, exposure to environmental toxins called per- and polyfluoroalkyl substances was linked to worse kidney function and other signs of kidney damage.
The Keck School of Medicine of USC has received a generous $100,000 donation from PUMA for the Selena Gomez Fund for Lupus Research, two years after the singer/actress established the fund.
American Society of Nephrology (ASN) publications contribute to the improved health of more than 850,000,000 people worldwide affected by kidney diseases—including 40 million Americans.
Padmanee Sharma, M.D., Ph.D., professor of Genitourinary Medical Oncology and Immunology at The University of Texas MD Anderson Cancer Center, has been recognized for her innovative work understanding factors that enhance and hinder cancer immunotherapy. Sharma will receive the William B. Coley Award for Distinguished Research in Tumor Immunology, awarded annually by the Cancer Research Institute (CRI), at an annual meeting co-sponsored by CRI in New York Sept. 30 to Oct. 3.
Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research. Findings from the study, led by Boyi Gan, Ph.D., associate professor, Department of Experimental Radiation Oncology, were published in the Sept. 10 online issue of Nature Cell Biology.
The National Institutes of Health (NIH) has awarded New York University nearly $66 million over the next five years to study how exposure to environmental factors influences children’s health. This new funding is an extension of a previous award of nearly $15 million over the last two years from an NIH initiative called Environmental influences on Child Health Outcomes (ECHO), which investigates how a range of environmental factors in early development – from conception through early childhood – affects the health and development of children and adolescents.
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