Myositis experts available to talk about Myositis during Rare Disease Month
Myositis Association
Together with other rare disease organizations, The Myositis Association is encouraging those who live with myositis diseases to Celebrate Your Rare by speaking out about the challenges they face and the need for more research into the causes, treatments, and possible cures for these diseases.
Researchers from Weill Cornell Medicine have used human embryonic stem cells to create a new model system that allows them to study the initiation and progression of small cell lung cancer (SCLC). The study, which will be published February 8 in the Journal of Experimental Medicine, reveals the distinct roles played by two critical tumor suppressor genes that are commonly mutated in these highly lethal cancers.
Researchers at Washington University School of Medicine in St. Louis have discovered clues to a particularly deadly form of rejection that can follow lung transplantation. Called antibody-mediated rejection, the condition remains impervious to available treatments and difficult to diagnose. The researchers have identified, in mice, a process that may prevent the condition and lead to possible therapies to treat it.
The International NCD Economics Research Network, a network of economists co-chaired by the independent, nonprofit research institute RTI International, the U.S. Centers for Disease Control and Prevention (CDC) and the University of Illinois at Chicago, has released a collection of articles on the economic reasons for prioritizing the prevention and control of non-communicable diseases (NCDs).
Two chemicals widely used to flavor electronic cigarettes may be impairing the function of cilia in the human airway, according to a new study led by Harvard T.H. Chan School of Public Health.
The American Thoracic Society has developed a new clinical practice guideline for home oxygen therapy for children. The guideline appears in the Feb. 1 edition of the Society’s American Journal of Respiratory and Critical Care Medicine.
Organic compounds from perfume, food, fabrics and soaps coat indoor surfaces. The film commonly found in our homes can impact the air we breathe and our health. Yet the details of how these compounds interact microscopically with indoor surfaces are not fully known. Researchers are learning more.
Many South Asian immigrants from countries where tuberculosis (TB) is common do not get tested even though they are at high risk for developing the disease, according to a recent study by Rutgers University and St. Peter’s University Hospital.
Experimenting with mice, Johns Hopkins Medicine researchers report that a low-calorie diet prevented asthma symptoms regardless of the diet’s fat and sugar content. The researchers also say they found that obesity resulting from a high-calorie diet led to asthma symptoms in the animals by causing lung inflammation, and a drug that blocks inflammation eased those symptoms.
John Theurer Cancer Center at Hackensack Meridian Health Hackensack University Medical Center announced today that it is leading enrollment worldwide for WIZARD 201G, a global Phase 2 study in glioblastoma (GBM). The trial, sponsored by Boston Biomedical, is evaluating DSP-7888, an investigational cancer vaccine, in combination with bevacizumab for recurrent disease.
Vanderbilt vaccine researchers are enrolling adult volunteers in a National Institutes of Health (NIH)-sponsored Phase II clinical trial that will study a next generation pertussis vaccine that may protect people from whooping cough.
Regionalizing lung cancer surgery is not only feasible, it’s also effective for patients, resulting in shorter hospital stays and fewer complications
Research from Rutgers Cancer Institute of New Jersey examined a potential approach to cancer therapy that disrupts a cancer cell’s ‘fuel supply’ by targeting a cellular survival mechanism known as autophagy. Using laboratory models for LKB1-deficient KRAS-mutant non-small cell lung cancer, they found that autophagy ablation reduced the frequency of tumor initiation and tumor growth in Lkb1-deficient lung tumors.
Fish oil does not appear to improve asthma control in adolescents and young adults with uncontrolled asthma who are overweight or obese, according to new research published online in the Annals of the American Thoracic Society.
An open label Phase 3 study conducted at Ann & Robert H. Lurie Children’s Hospital of Chicago and other centers established that a combination of cystic fibrosis drugs lumacaftor and ivacaftor is safe and effective in children aged 2-5 years, whose disease is caused by two copies of F508del-CFTR gene mutation – the most common and severe form of cystic fibrosis.
Rutgers Cancer Institute of New Jersey researcher Sharon R. Pine, PhD, has received a $200,000 Lung Cancer Discovery Award from the American Lung Association to examine potential new treatment options for patients with a sub-type of non-small cell lung cancer.
Scientists predict that certain regions of the United States will experience higher levels of pollutants that cause smog, acid rain and respiratory problems due changes in forest soils from climate change.
The world's first genetic sequencing of precancerous lung lesions could pave the way for very early detection and new treatments, reports a new study led by UCL researchers.
As levels of ozone and fine particulate pollution (PM2.5) rise, more patients end up in the ER with breathing problems, according to the largest U.S. study of air pollution and respiratory emergency room visits of patients of all ages. The study was published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
When new guidelines recommend that patients with severe ARDS be face-down most of the day, integrating the logistically challenging repositioning procedure into clinical practice requires a team approach. Christiana Care Health System shares how it made prone positioning the standard of care in its ICUs.
They say everything is bigger in Texas and this year Dallas is hosting the ATS 2019 International Conference, the biggest gathering of scientists and clinicians in pulmonary, critical care, and sleep medicine.
Surgeon and researcher Frederick L. Grover, MD, of the University of Colorado, was awarded the 2019 John P. McGovern Compleat Physician Award by the Houston Academy of Medicine and Harris County Medical Society.
Vanderbilt University Medical Center (VUMC) set a new record for total transplants among its five organ specialties in 2018 with more than 500 transplants.
Complication rates following invasive diagnostic procedures for lung abnormalities were twice as high in community settings compared to those reporter in lung screening trials, according to an MD Anderson study.
People with cancer are more than four times more likely to commit suicide than people without cancer, according to Penn State College of Medicine researchers.
Researchers have found a novel, pathogenic entity that is a fundamental link between chronic inflammation and tissue destruction in lungs of patients with COPD. These exosomes from activated neutrophils caused COPD damage when they were instilled into the lungs of healthy mice.
روتشستر، مينيسوتا — نشر باحثون من Mayo Clinic، بالتعاون مع باحثين من كلية ويك فورست للطب و مركز العلوم الصحية بجامعة تكساس في سان أنطونيو، نتائج دراسة سريرية حول سلامة وجدوى إزالة خلايا مُسنّة من مجموعة صغيرة من المرضى المصابين بالتليف الرئوي. وعُرِضت نتائج الدراسة في مجلة الطب الحيوي "إي بايو مديسن" EBioMedicine.
John “Chip” Tilton, MD, of Case Western Reserve University School of Medicine will receive $300,000 from the Dr. Ralph and Marian Falk Medical Research Trust to develop a virus-based “nanoPOD” (nanoscale PrOtein Delivery) platform to help treat rare genetic diseases. Tilton’s project will address a major challenge in developing nanoscale therapeutics: finding ways to deliver them to the right location inside the body.
Having two or more non-communicable diseases (multimorbidity) costs the country more than the sum of those individual diseases would cost, according to a new study published this week in PLOS Medicine by Tony Blakely from the University of Otago, New Zealand, and colleagues.
With $13.4 million dollars in awards from the National Institutes of Health (NIH), the University of Pennsylvania School of Nursing (Penn Nursing) retains its top spot for research funding for the 2018 fiscal year, among other schools of nursing. This is the second consecutive year Penn Nursing has earned first place.
Summaries of recent Fred Hutch research, with links for additional background and media contacts.
Smoking is a hard habit to kick but when you do, the health benefits are almost immediate. As you re-invent yourself as a non-smoker, here are three straightforward ways to combat weight gain and keep you distracted while coming off that smoking habit.
One of the classic cold symptoms is a cough. Usually after a week or so, the cold runs its course and most of the symptoms go away. But for some people, the cough remains. So why do we cough and what can we do about it? Here are five things you should know about that persistent cough.
Rutgers Cancer Institute experts share more about the importance of preventative screenings for colorectal and lung cancers.
In a new study by Yale Cancer Center (YCC), scientists suggest that as the number of clinical trials in cancer immunotherapy grows exponentially, some caution should be exercised as we continue to better understand the biology of these new therapeutic targets.
Scientists at McMaster University have discovered several new biomarkers from a single drop of blood that could allow earlier and more definitive detection of cystic fibrosis (CF), a genetic disease which strikes both children and adults, causing chronic problems with the digestive system and the lungs.
Getting the heart pumping with aerobic exercise, like walking or cycling for 35 minutes three times a week, may improve thinking skills in older adults with cognitive impairments, according to a study published in the December 19, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology. After six months of exercise, study participants’ scores on thinking tests improved by the equivalent of reversing nearly nine years of aging.
A focus on high-risk tuberculosis patients may be the answer to stalled progress in stamping out the illness in the United States.
In a tuberculosis screening and treatment initiative covering the entire population of Tibetan refugee schoolchildren in northern India, a team directed by researchers at Johns Hopkins Medicine and the University of Wisconsin says it has found not only a startlingly high prevalence of TB disease and infection, but also a potentially workable strategy to eliminate the disease in a large, high-risk group.
Researchers at McMaster University have identified trends linking health and lifestyle factors like access to public transit, the variety of fresh fruits and vegetables in grocery stores, the prices of popular foods, the availability and prices of cigarettes and alcohol, and the promotion, or lack thereof, of healthy foods in restaurants. The study findings are based on detailed data collected across Canada’s 10 provinces.
Results of a medical records study of more than 7,000 patients awaiting a lung transplant in the United States affirm the basis of a court filing in 2017 that called the organ allocation system geographically “rigged” in some regions of the nation.
The average primary care doctor needs to work six more hours a day than they already do, in order to make sure their patients get all the preventive and early-detection care they deserve, a new study finds. Fortunately, the new study was written as a parody -- no one is asking doctors to work past midnight every night. At least, not yet.
Manitoba has the highest provincial incident rate of active tuberculosis (TB) in Canada, and stopping its spread depends on, among other things, the availability of high-quality, comprehensive data to ensure early and complete treatment, according to a new study by the Manitoba Centre for Health Policy (MCHP) at the University of Manitoba.
Researchers at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago, and colleagues, used a blood test and microarray technology to identify distinct molecular signatures in children with cystic fibrosis. These patterns of gene expression ultimately could help predict disease severity and treatment response, and lead to therapies tailored to each patient’s precise biology.
Julia and Cameron were born with cystic fibrosis (CF), an inherited, chronic, progressive disease that affects respiratory and pancreatic function. Both artists and athletes, they refuse to let the disease define their lives, and consider themselves integral partners in the care they receive at the comprehensive Cystic Fibrosis Center at Rutgers Robert Wood Johnson Medical School, one of only three accredited CF centers in New Jersey. In 2016, the CF Center ranked highest nationally and in New Jersey in a composite score for lung function and nutritional status.
Mayo Clinic研究人员发现,一种在癌症治疗过程中用于治疗患者血栓的口服药物——阿哌沙班是安全有效的。 与低分子量的肝素相比,这种药物的大出血事件和血栓复发率都较低。这些研究结果由 Mayo Clinic 心脏病学专家、医学博士Robert McBane II在在美国血液学学会年会上提出。
In a letter to EPA Acting Administrator Andrew Wheeler members of the scientific community expressed concern about the agency’s decision to dissolve pollutant-specific advisory panels, including one charged with setting the National Ambient Air Quality Standard or NAAQS for airborne particulate matter or PM.
Researchers at The University of Texas MD Anderson Cancer Center have identified a link between an enzyme tied to cancer formation and therapy resistance in patients with epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC).