A team of researchers from UCLA, Cedars-Sinai and the Cystic Fibrosis Foundation has developed a first-of-its-kind molecular catalog of cells in healthy lungs and the lungs of people with cystic fibrosis.
After the Most Comprehensive Review to Date, a Panel of Leading Medical Experts Conclude that
Ivermectin Should be Systematically and Globally Adopted for the Prevention and Treatment of COVID-19
In their lab, CRCHUM scientists Emmanuelle Brochiero and Damien Adam are studying ways of better predicting the efficacy of medications and helping injured lungs repair and regenerate.
A team of researchers from UCLA, Cedars-Sinai and the Cystic Fibrosis Foundation has developed a first-of-its-kind molecular catalog of cells in healthy lungs and the lungs of people with cystic fibrosis. The findings could help scientists in their search for specific cell types that represent prime targets for genetic and cell therapies for cystic fibrosis.
Research finds that a commonly used risk-prediction model for lung cancer does not accurately identify high-risk Black patients who could benefit from early screening.
To mark Clean Air Month, the Pulmonary Fibrosis Foundation (PFF) aims to increase public understanding of the role air pollution has in the development of interstitial lung diseases (ILD) such as pulmonary fibrosis (PF), including how polluted air can make you sick and the telltale signs to be aware of.
A pair of Mayo Clinic studies shed light on something that is typically difficult to see with the eye: respiratory aerosols. Such aerosol particles of varying sizes are a common component of breath, and they are a typical mode of transmission for respiratory viruses like COVID-19 to spread to other people and surfaces.
April 8, 2021 – The Division of Rheumatology, Department of Medicine, Faculty of Medicine (CU Medi), Chulalongkorn University and King Chulalongkorn Memorial Hospital, the Thai Red Cross Society (Chulalongkorn Hospital), in collaboration with the Departments of Hematology, Pulmonary and Critical Care Medicine, and Infectious diseases, held a press conference on “Thailand’s first successful treatment of systemic sclerosis patients with pulmonary fibrosis by stem cell transplantation“.
In its latest clinical practice guideline on community-acquired pneumonia the American Thoracic Society’s guidelines panel addresses the use of nucleic acid-based testing for non-influenza viral pathogens. The guideline was published online in the May 1 issue of the American Journal of Respiratory and Critical Care Medicine. An explainer video may be viewed here.
A new study, presented today at the AATS 101st Annual Meeting, found that severely ill COVID-19 patients treated with ECMO did not suffer worse long-term outcomes than other mechanically-ventilated patients.
To anyone else, it’s just a walk around the block. But for Frank Coburn, 57, and his wife, it’s a miracle. A miracle that resulted from Coburn becoming the first Southern Californian—and possibly first in the U.S.—to receive a minimally invasive double lung transplant. The procedure was performed at the Smidt Heart Institute.
Asthma exacerbations rose following a catastrophic Christmas Eve fire that destroyed pollution controls at the Clairton Coke Works – the largest such facility in the nation, a University of Pittsburgh Graduate School of Public Health analysis concludes.
Using a newly developed mouse model of acute lung injury, researchers found that exposure to the SARS-CoV-2 spike protein alone was enough to induce COVID-19-like symptoms including severe inflammation of the lungs.
A new study found that non-pungent synthetic analog of capsaicin — the compound that makes chili peppers hot — made small cell lung cancer cells more responsive to treatment. Small cell lung cancer is a very aggressive form of cancer with a low survival rate.
Although bronchopulmonary dysplasia (BPD)—a chronic lung disease affecting newborns—is the most common complication of preterm birth, it remains difficult to diagnose and treat. Researchers from Fundación INFANT in Buenos Aires, Argentina, and The University of Oklahoma Health Sciences Center, hope to address these difficulties using machine learning to inform the clinical care of preemies with BPD.
A new treatment is among the first known to reduce the severity of acute respiratory distress syndrome caused by the flu in animals, according to a new study.
The American College of Radiology® (ACR®) today released an update to its ACR Appropriateness Criteria® (ACR AC), which includes 211 diagnostic imaging and interventional radiology topics with more than 1,000 clinical variants covering approximately 1,900 clinical scenarios.
Currently, there are no evidence-based rules that help physicians in the Emergency Department (ED) predict if a child with community-acquired pneumonia will have a mild disease course that can be treated at home or a more severe illness that requires hospitalization. A recent study published in the journal Pediatrics found that the predictive accuracy of clinical judgement was generally fair, but clinicians were least accurate when predicting progression to severe disease in children initially classified as having “low to moderate” risk, which accounts for a large portion of children presenting with pneumonia.
DALLAS – April 24, 2021 – UT Southwestern Medical Center scientists have identified the first cases of the Brazilian variant of COVID-19 infection in North Texas using next-generation sequencing technologies along with PCR testing.
Penn Medicine has been selected as one of five sites across the country to serve as a Center of Excellence for Influenza Research and Response (CEIRR), with the goal of better understanding influenza viruses around the world along with learning about the viral strains that have the potential to cause pandemics. Penn Medicine has been awarded nearly $7 million in first-year funding.
What can you expect at the ATS 2021 International Conference, taking place May 14-19? We’ve gone ahead and identified some “hot topics” for your consideration.
Investigators at Wake Forest School of Medicine, part of Wake Forest Baptist Health, have identified a set of new genetic markers that could potentially lead to new personalized treatments for lung cancer.
Wheezing, coughing that doesn’t stop, a pale and sweaty face: clinically, severe asthma attacks look very similar from patient to patient. But biologically, not all severe asthma is the same—and a team of scientists has, for the first time, identified the key difference in people, a finding that has important implications for treatment.
In a series of experiments that began with amoebas — single-celled organisms that extend podlike appendages to move around — Johns Hopkins Medicine scientists say they have identified a genetic pathway that could be activated to help sweep out mucus from the lungs of people with chronic obstructive pulmonary disease a widespread lung ailment.
E-cigarettes that deliver a cigarette-like amount of nicotine are associated with reduced smoking and reduced exposure to a major cancer-causing chemical, or carcinogen, in tobacco even with concurrent smoking, according to a new study led by researchers at Penn State College of Medicine and Virginia Commonwealth University (VCU). The study provides new and important information for smokers who may be trying to use e-cigarettes as a means to cut down on their smoking habit and lower their exposure to harmful toxicants.
A new commentary published online in the Annals of the American Thoracic Society provides an exhaustive examination of published research that discusses whether air pollution may be linked to worse COVID-19 outcomes. The studies that the authors examined look at several potential disease mechanisms, and also at the relationship between pollution, respiratory viruses and health disparities.
Even before the pandemic made telehealth a hot topic, people with minor urgent health needs had started to turn to companies that offer on-demand video chats. Some insurers and employers support this, hoping it might reduce in-person care, including emergency department visits. But a new study casts some doubt on whether that will actually happen.
In May 2020, a team led by thoracic surgeon Konrad Hoetzenecker of the Department of Surgery of MedUni Vienna and Vienna General Hospital performed a lung transplant on a 44-year-old patient who had been seriously ill with Covid-19, making her the first patient in Europe to receive a lung transplant for this indication.
Children hospitalized with breathing problems due to infection with respiratory syncytial virus (RSV) are likely to get sicker and remain hospitalized if they have high levels of defective copies of the virus, according to a new study by researchers at Washington University School of Medicine in St. Louis.
"SARS-CoV-2 and SARS-CoV are highly similar genetically, generate a homologous repertoire of viral proteins, and use the same receptor to infect human cells.
The College of American Pathologists (CAP), in collaboration with five other societies, developed a draft evidence-based clinical practice guideline that aims to optimize PD-L1 testing for patients with non-small cell lung cancer (NSCLC) who are being considered for immunooncology therapy.
Mount Sinai researchers have found that a widely available and inexpensive drug targeting inflammatory genes has reduced morbidity and mortality in mice infected with SARS-CoV-2, the virus that causes COVID-19.
Through his role on the U.S. Preventive Services Task Force, UVA Health’s Li Li, MD, PhD, MPH, has helped develop new lung cancer screening guidelines that expand screenings to more high-risk patients.
Noninfluenza respiratory viral infections (NIRV) are associated with illness and death rates similar to influenza in hospitalized adults, according to new research in CMAJ (Canadian Medical Association Journal).