Machine Learning Helps Predict Protein Functions
Department of Energy, Office of ScienceTo engineer proteins for specific functions, scientists change a protein sequence and experimentally test how that change alters its function. Because there are too many possible amino acid sequence changes to test them all in the laboratory, researchers build computational models that predict protein function based on amino acid sequences. Scientists have now combined multiple machine learning approaches for building a simple predictive model that often works better than established, complex methods.