Feature Channels: Dermatology

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Current testing for Lyme disease, called the standard 2-tiered approach or the STT, involves running two complex assays (ELISA and western blot) to detect antibodies against the bacterium, and requires experienced personnel in a lab, and a few hours to carry out and interpret. Columbia biomedical engineers have developed a rapid microfluidic test that can detect Lyme disease with similar performance as the STT in a much shorter time—15 minutes.

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A new study led by UCLA researchers, have found that obtaining a second opinion from pathologists who are board certified or have fellowship training in dermatopathology can help improve the accuracy and reliability of diagnosing melanoma, one of the deadliest and most aggressive forms of skin cancer.

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Atopic dermatitis (also known as eczema) is a common skin condition in babies. It affects up to 25% of children, and an estimated 60% of people with eczema develop it during their first year of life. While there is no cure, dermatologists from the American Academy of Dermatology say most cases can be controlled with a customized skin care plan, which may include moisturizers, prescription medications and strategies to eliminate triggers.

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May also help predict therapeutic responses

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To conduct preclinical testing of locally-acting topical dermal and ophthalmic drug product formulations

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In a new study published in EBioMedicine, researchers with Moffitt Cancer Center’s Donald A. Adam Melanoma and Skin Cancer Center of Excellence reveal that differences at the single-cell level can predict responses to initial BRAF inhibitor therapy, and that leveraging these differences may improve patient outcomes.

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Head and neck melanoma among pediatric, adolescent and young adult populations in the United States and Canada increased by 51.1% from 1995 to 2014, per research from Saint Louis University.

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Results suggest that the combined treatment can lower the effective chemotherapy dosage, reduce side effects, improve tumor cell apoptosis, and reduce tumor cell migration.

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October is National Breast Cancer Awareness Month, a great time to spread the word about the importance breast cancer screening and being alert to breast changes. After skin cancer, breast cancer is the most common type of cancer diagnosed in women in the U.S.

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Millions of people with severe burns or diabetic skin ulcers could benefit from an experimental enhancement to a next-generation covering that is already healing difficult wounds.

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It’s often difficult to manage patients with lichen planus, but new research identifies a target that existing medications are able to address.

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Using a small noncoding RNA, microRNA 211, and tools that track the stability and decay of the protein-coding and noncoding RNAs in lab-grown melanoma cells, a team led by a Johns Hopkins Kimmel Cancer Center researcher identified highly unstable RNA molecules in human melanomas, including a novel miR-211 target gene DUSP3.

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A new study from a Binghamton University research team uses the topography of human skin as a model not for preventing cracks but for directing them in the best way possible to avoid critical components and make repairs easy.

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Skin cancer is the most common cancer in the United States, affecting one in five Americans during their lifetime. To help raise awareness of skin cancer prevention and detection, the American Academy of Dermatology will host Skin Cancer, Take a Hike!™ – Chicago on Sat., Sept. 28 in Elk Grove Village. The scenic, four-mile walk at Busse Woods—part of the AAD’s SPOT Skin Cancer™ campaign to create a world without skin cancer—will benefit skin cancer prevention and detection programs, including free skin cancer screenings, sunscreen dispensers, and permanent shade structures where children learn and play.

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Reversing baldness could someday be as easy as wearing a hat, thanks to a noninvasive, low-cost hair-growth-stimulating technology developed by engineers at the University of Wisconsin–Madison.

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Studying natural defenses in maize, a staple of diets around the world, UC San Diego biologists describe how they combined an array of scientific approaches to clearly define six genes that encode enzymes responsible for the production of key maize antibiotics known to control disease resistance.

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The American Academy of Dermatology has honored board-certified dermatologist Karen Wiss, MD, FAAD, as a Patient Care Hero for her role in treating a patient born with an extremely rare skin disease caused by a genetic mutation. The condition, known as recessive dystrophic epidermolysis bullosa (RDEB), is commonly called “the butterfly disease,” because it causes skin to be extremely fragile and blister easily after minor rubbing or scratching. It affects fewer than one in 1 million people.

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The American Academy of Dermatology has honored dermatologist Gloria Xu, MD, PhD, FAAD, and oncologist Mark Albertini, MD, as Patient Care Heroes for their leadership in launching a melanoma tumor board to optimize care for melanoma patients at the University of Wisconsin School of Medicine and Public Health.

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In a study published in mBio,, Jorge Benach and Rafal Tokarz, and their co-authors at Stony Brook University and Columbia University, reported on the prevalence of multiple agents capable of causing human disease that are present in three species of ticks in Long Island.

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Tattoos used to be considered permanent, but thanks to advances in laser technology, dermatologists from the American Academy of Dermatology say today’s lasers can get rid of tattoos more safely and effectively, including removing tattoo ink with fewer treatments and treating ink colors that were once difficult to remove.

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While there are several effective options for treating non-melanoma skin cancers, some may result in better cosmetic appearance after treatment, according to researchers.

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Scientists are using nanoparticle screening on personal care products and finding previously thought toxic chemicals may not be harmful. In Biomicrofluidics, researchers discuss their work successfully using microchips to demonstrate titanium dioxide, a chemical found in most sunscreens, not only is nontoxic but also offers protection against ultraviolet damage to skin cells.

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Anyone who has gone through the stress and discomfort of raw, irritated skin knows the relief that comes with slathering on a creamy lotion. Topical creams generally contain a few standard ingredients

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Melanoma is a deadly form of skin cancer that has been increasing in the U.S. for the past 30 years. Nearly 100,000 new cases of melanoma are diagnosed every year, and 20 Americans die every day from it

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Researchers at Binghamton University, State University of New York have discovered the mechanism through which ultraviolet radiation, given off by the sun, damages our skin.

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Johns Hopkins researchers report that prurigo nodularis (PN), a skin disease characterized by severely itchy, firm bumps on the skin, may be associated with other inflammatory skin disorders as well as systemic and mental health disorders. Compared with other skin diseases, however, not much is known about PN. While symptoms of PN can be managed, no cures exist. Researchers were looking to determine associated conditions that are more common in patients with PN, compared with similar patients without PN.

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A new study from Penn researchers has identified a key regulator of a process that controls skin regeneration, which can control whether cells turn into a common skin cancer.

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A study published this week in the journal Pigment Cell & Melanoma Research has found that genes have a greater influence than previously thought not only on the number of moles you have but also where they are on your body.

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The maturation of skin microbial communities during childhood is important for the skin health of children and development of the immune system into adulthood

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Head lice affect about six to 12 million children, ages three to 12, each year in the United States. Although head lice are not known to carry disease, dermatologists from the American Academy of Dermatology say an infestation can cause some uncomfortable symptoms. Knowing how to spot the signs of head lice early can help prevent the infestation from spreading.

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The Infectious Diseases Society of America (IDSA), the American Academy of Neurology (AAN), and the American College of Rheumatology (ACR) have extended the public comment period for the draft of their joint guidelines for the prevention, diagnosis, and treatment of Lyme disease for an additional 30 days. The deadline to submit comments is now Sept. 9, 2019.

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Burn injuries can diminish your confidence, campers say. Having a supportive community helps both physically and emotionally. Downloadable media assets are available.

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Diane and Phil Hannah of New Milford, Connecticut faced a series of health problems — including Phil’s skin cancer diagnosis — that made it difficult for them to keep up with everyday tasks, like shopping for groceries and preparing meals. The Eating Well program supported Diane and Phil during this challenging time by providing vouchers for free, nutritious meals from the New Milford Hospital café after each of Phil’s radiation therapy sessions. The Eating Well program aims to improve the overall well-being of patients and caregivers, and is fully supported by generous donors. Eating Well is a component of New Milford Hospital’s Plow to Plate program. Plow to Plate meals are freshly prepared with locally sourced, organic ingredients.

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An international team of dermatology experts including two from Henry Ford Hospital in Detroit have published – for the first time in North America - guidelines for diagnosing and managing hidradenitis suppurativa, a chronic and debilitating skin disease for which there is no cure.

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BIDMC podiatric surgeon Thanh Dinh, DPM, shares five simple tips for keeping your feet feeling their best.

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The George Washington University Cancer Center was selected as the first global site for a clinical trial for patients with high-risk cutaneous squamous cell carcinoma.

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A new study led by researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) and collaborators at Northwestern University (NW) and Oregon Health and Science University (OHSU) investigated whether genetic testing would motivate people at risk of developing melanoma to alter their behavior in order to reduce their risk. The study was published today in Genetics in Medicine.

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Skin cancer can strike anyone — and exposure to the sun’s ultraviolet rays is a leading risk factor.

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As the largest organ of the human body our skin is astounding. It protects us from infection, endures radiation, senses temperature, and is flexible enough to withstand our everyday activities.

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Data from two long-term study groups including nearly 125,000 health professionals in the U.S. were used to evaluate the association between intake of vitamin A, through diet and supplementation, and risk of cutaneous squamous cell cancer during a follow-up period of more than 26 years.

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The more rainfall a region in sub-Saharan Africa gets, the more mosquitoes proliferate there and the more likely its residents will sleep under their insecticide-treated bed nets to prevent malaria transmission, a new study from the Johns Hopkins Center for Communication Programs suggests. CCP is based at the Johns Hopkins Bloomberg School of Public Health.

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When temperatures throughout the sizzling Southwestern U.S. climb to over 100 degrees, the pavement can get hot enough to cause second-degree burns on human skin in a matter of seconds. In a new study published in the Journal of Burn Care & Research, a team of surgeons from the UNLV School of Medicine reviewed related admissions to a local burn center - and the temperature on the date of the visit - to determine how hot is too hot.

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Jefferson researchers unveil first demonstration of heritable mutations behind non-alcoholic fatty liver disease

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When board-certified dermatologists help prepare patients for treatment, outcomes improve

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Treatment can effectively control sweating and improve patients’ daily life and quality of life

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Scientists studying poison ivy rashes in mice have identified two proteins and a neurotransmitter involved in poison ivy itch in mice. They could be potential drug targets that could lead to treating the aggravating itch in people.

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Research highlights the need for further education around the dangers of UV exposure

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The right diagnosis is key for a successful treatment plan

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As Lyme disease increases, researchers have taken a significant step toward finding new ways to prevent its transmission. The experts, who include a pioneer in Lyme disease discovery, have sequenced the genome of the animal carrying the bacteria that causes the illness. The advance by researchers at the University of California, Irvine and colleagues provides a launching pad for fresh approaches to stopping Lyme disease from infecting people.