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Newswise: Charities can benefit by giving contributors more control over their donations, study shows
Released: 16-Mar-2022 9:40 AM EDT
Charities can benefit by giving contributors more control over their donations, study shows
University of Notre Dame

Donors feel more personal control over how their time (versus money) is used, according to new research from the University of Notre Dame

Newswise: Tracking arsenic contamination to former orchards
Released: 16-Mar-2022 8:00 AM EDT
Tracking arsenic contamination to former orchards
American Society of Agronomy (ASA), Crop Science Society of America (CSSA), Soil Science Society of America (SSSA)

Arsenic is a major drinking water contaminant, often linked to the bedrock where wells are drilled in the Northeastern part of the United States. However, new research suggests that pesticides used 100 years ago may also be to blame.

Newswise: Bacterial enzyme makes new type of biodegradable polymer
14-Mar-2022 7:00 AM EDT
Bacterial enzyme makes new type of biodegradable polymer
American Chemical Society (ACS)

Researchers reporting in ACS Central Science have identified a previously unknown bacterial enzyme that can make a new type of polysaccharide similar to the biopolymer chitin. The new molecule is biodegradable and could be useful for drug delivery, tissue engineering and other biomedical applications.

Released: 16-Mar-2022 7:05 AM EDT
Successful transfemoral-transcatheter aortic valve replacement in high-risk patients with a grade 4 atheroma in the ascending aorta: cerebral protection with a filter device
General Thoracic and Cardiovascular Surgery

… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

Released: 16-Mar-2022 7:05 AM EDT
Characterization of Cerebral Embolic Capture Using the SENTINEL Device During Transcatheter Aortic Valve Implantation in Low to IntermediateRisk Patients: The SENTINEL-LIR Study
Circulation: Cardiovascular Interventions

… Post-TAVR stroke causes acute and long-term morbidity and mortality. The stroke rate 30 days after TAVR was reported as 3.4% in low-risk … TAVR may reduce the incidence of ischemic stroke and in-hospital mortality.However, the effectiveness of …

Released: 16-Mar-2022 7:05 AM EDT
Cerebral Protection in TAVR—Can We Do Without? A Real-World All-Comer Intention-to-Treat Study—Impact on Stroke Rate, Length of Hospital Stay, and Twelve …
Journal of Personalized Medicine

… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

Released: 16-Mar-2022 7:05 AM EDT
Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
Journal of Clinical Medicine

… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%), and periprocedural AF was not associated with higher risk of stroke. Risk of stroke after TAVR can be affected by various factors, including antithrombotic regimens …

Newswise: LLNL study on tumor/immune cell interaction could impact cancer immunotherapies
15-Mar-2022 3:30 PM EDT
LLNL study on tumor/immune cell interaction could impact cancer immunotherapies
Lawrence Livermore National Laboratory

Lawrence Livermore National Laboratory (LLNL) scientists exploring the interaction between cancer cells and the extracellular matrix (ECM) — the “scaffolding” of organs — found that proteins in the ECM can dramatically impact the immune system’s ability to kill tumors.

   
Released: 15-Mar-2022 7:05 PM EDT
Increased support needed for a coordinated global HIV and COVID-19 response
HIV Vaccine Trials Network

In a JAMA perspective piece, leading infectious disease researchers call for a coordinated response to HIV and COVID-19 globally, building on the successes of key donor programs such as the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) program and Global Fund to Fight AIDS, TB and Malaria (GFATM).

Newswise:Video Embedded marine-snail-inspires-fast-acting-injectable-insulin-for-better-diabetes-control
VIDEO
Released: 15-Mar-2022 4:20 PM EDT
Marine Snail Inspires Fast-Acting Injectable Insulin for Better Diabetes Control
University of Utah Health

Scientists have created a modified form of human insulin that they hope could give patients with diabetes better, more immediate control over their blood sugar.

   
Released: 15-Mar-2022 4:00 PM EDT
Scale-up of Digital Innovations in Health Care: Expert Commentary on Enablers and Barriers
Journal of Medical Internet Research

Health care delivery is undergoing a rapid change from traditional processes toward the use of digital health interventions and personalized medicine. This movement has been accelerated by the COVID-19 crisis as a response to the need to guarantee ac...

Released: 15-Mar-2022 4:00 PM EDT
Improving the Development and Implementation of Audit and Feedback Systems to Support Health Care Workers in Limiting Antimicrobial Resistance in the Hospital: Scoping Review
Journal of Medical Internet Research

For eHealth technologies in general and audit and feedback (AF) systems specifically, integrating interdisciplinary theoretical underpinnings is essential, as it increases the likelihood of achieving desired outcomes by ensuring a fit among eHealth technology, stakeholders, and their context.

Released: 15-Mar-2022 3:30 PM EDT
The Mediating Role of Patients’ Trust Between Web-Based Health Information Seeking and Patients’ Uncertainty in China: Cross-sectional Web-Based Survey
Journal of Medical Internet Research

In the physician-patient relationship, patients’ uncertainty about diseases and the lack of trust in physicians not only hinder patients’ rehabilitation but also disrupt the harmony in this relationship.

Released: 15-Mar-2022 3:00 PM EDT
Use of Mobile and Wearable Artificial Intelligence in Child and Adolescent Psychiatry: Scoping Review
Journal of Medical Internet Research

Mental health disorders are a leading cause of medical disabilities across an individual’s lifespan.

Released: 15-Mar-2022 3:00 PM EDT
Modeling Access Across the Digital Divide for Intersectional Groups Seeking Web-Based Health Information: National Survey
Journal of Medical Internet Research

The digital divide refers to technological disparities based on demographic characteristics (eg, race and ethnicity). Lack of physical access to the internet inhibits online health information seeking (OHIS) and exacerbates health disparities.

Released: 15-Mar-2022 3:00 PM EDT
The Public Perception of the #GeneEditedBabies Event Across Multiple Social Media Platforms: Observational Study
Journal of Medical Internet Research

In November 2018, a Chinese researcher reported that his team had applied clustered regularly interspaced palindromic repeats or associated protein 9 to delete the gene C-C chemokine receptor type 5 from embryos and claimed that the 2 newborns would have lifetime immunity from HIV infection, an event referred to as #GeneEditedBabies on social media platforms.

Released: 15-Mar-2022 2:45 PM EDT
Workarounds in Electronic Health Record Systems and the Revised Sociotechnical Electronic Health Record Workaround Analysis Framework: Scoping Review
Journal of Medical Internet Research

Electronic health record (EHR) system users devise workarounds to cope with mismatches between workflows designed in the EHR and preferred workflows in practice. Although workarounds appear beneficial at first sight, they frequently jeopardize patient safety, the quality of care, and the efficiency of care.

Released: 15-Mar-2022 2:30 PM EDT
Influence of Forced Online Distance Education During the COVID-19 Pandemic on the Perceived Stress of Postsecondary Students: Cross-sectional Study
Journal of Medical Internet Research

One of the most significant changes in the majority of postsecondary educational institutions was the closure of those institutions and the shift of educational activities to online distance learning formats as a result of the COVID-19 pandemic.

Released: 15-Mar-2022 1:30 PM EDT
Emergency Medicine and Anesthesiology Specialties See Abnormally High Increases in Price
Johns Hopkins University Carey Business School

Emergency Medicine and Anesthesiology are two outlier medical specialties that had abnormally high increases in charges from 2010 to 2019, according to a new study in the Journal of General Internal Medicine by researchers at Johns Hopkins University and University of Toronto.

Released: 15-Mar-2022 12:50 PM EDT
Senolytic drugs boost key protective protein
Mayo Clinic

Mayo Clinic researchers say senolytic drugs can boost a key protein in the body that protects older people against aspects of aging and a range of diseases. Their findings, which are published in eBioMedicine demonstrate this in mice and human studies. Senolytics developed at Mayo Clinic and given once clear the bloodstream of senescent or "zombie" cells. These cells contribute to multiple diseases and negative aspects of aging. This study shows that the removal of senescent cells significantly boosts the production of a protective protein called a-klotho.

Released: 15-Mar-2022 12:50 PM EDT
Combing the cosmos: New color catalog aids hunt for life on frozen worlds
Cornell University

Aided by microbes found in the subarctic conditions of Canada’s Hudson Bay, an international team of scientists has created the first color catalog of icy planet surface signatures to uncover the existence of life in the cosmos.

Released: 15-Mar-2022 12:25 PM EDT
Permafrost peatlands approaching tipping point
University of Leeds

Researchers warn that permafrost peatlands in Europe and Western Siberia are much closer to a climatic tipping point than previous believed.

Newswise: Fast-melting alpine permafrost may contribute to rising global temperatures
Released: 15-Mar-2022 12:15 PM EDT
Fast-melting alpine permafrost may contribute to rising global temperatures
University of Arizona

From the ancient sludge of lakebeds in Asia's Tibetan Plateau, scientists can decipher a vision of Earth's future.

Released: 15-Mar-2022 12:10 PM EDT
Elevated inflammation persists in immune cells months after mild COVID-19
Karolinska Institute

There is a lack of understanding as to why some people suffer from long-lasting symptoms after COVID-19 infection.

Released: 15-Mar-2022 12:05 PM EDT
Autistic defendants are being failed by the criminal justice system
University of Cambridge

The criminal justice system (CJS) is failing autistic people, argue researchers at the Autism Research Centre, University of Cambridge, after a survey of lawyers found that an overwhelming majority of their clients were not provided with adequate support or adjustments.

Newswise: Molecular Networks Could Explain Racial Disparity in Triple Negative Breast Cancer Deaths
Released: 15-Mar-2022 12:05 PM EDT
Molecular Networks Could Explain Racial Disparity in Triple Negative Breast Cancer Deaths
Johns Hopkins Medicine

Different activity in two molecular networks could help explain why triple negative breast cancers tend to be more aggressive in African American (AA) women compared with white American (WA) women, a new study led by Johns Hopkins Kimmel Cancer Center researchers suggests.

Newswise: Furthering fat loss in the fasting response
Released: 15-Mar-2022 12:00 PM EDT
Furthering fat loss in the fasting response
Osaka University

The coming of spring harkens spring cleaning; a time to de-clutter your home and discard things that are no longer needed.

Newswise: A Potential New Test for Diagnosing Lyme Disease
11-Mar-2022 3:30 PM EST
A Potential New Test for Diagnosing Lyme Disease
Tufts University

Researchers at Tufts University School of Medicine have identified a key testing area for Lyme disease that could potentially help clinicians diagnose the disease sooner, know whether treatment with antibiotics is working, and identify patients who have been reinfected.

   
Newswise: Drug-resistant bacteria flaunt their curves
Released: 15-Mar-2022 11:45 AM EDT
Drug-resistant bacteria flaunt their curves
Osaka University

If you’ve been hitting the gym and getting results, you know it’s time to strut your stuff; and it turns out bacteria feel the same way.

Newswise: The next frontier for African genomics - safeguarding African biodiversity
Released: 15-Mar-2022 11:40 AM EDT
The next frontier for African genomics - safeguarding African biodiversity
University of South Africa

The African BioGenome Project (AfricaBP) published a position paper in the journal Nature highlighting the goals, priorities, and roadmap of the impressive Africa-led effort to sequence the genomes of plants, animals, fungi, and protists that are endemic to the continent of Africa.

Released: 15-Mar-2022 11:30 AM EDT
Amino acid supplements reduce complications after fracture surgery
Wolters Kluwer Health: Lippincott

For patients recovering from fracture fixation surgery, dietary supplementation with conditionally essential amino acids (CEAA) reduces complications and prevents skeletal muscle wasting, concludes a clinical trial in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.

Newswise: Newly Published Study Shows Link Between Socioeconomic Deprivation and Premature Cardiovascular Mortality
Released: 15-Mar-2022 11:10 AM EDT
Newly Published Study Shows Link Between Socioeconomic Deprivation and Premature Cardiovascular Mortality
University Hospitals Cleveland Medical Center

A new study, completed by researchers at University Hospitals Harrington Heart & Vascular Institute, found people living in socially-deprived areas of the United States are more likely to die prematurely from cardiovascular complications.

Released: 15-Mar-2022 11:05 AM EDT
Study Shows mRNA Vaccine Technology Can Be Used For HIV Vaccines
Duke Health

Using mRNA technology like that in the COVID-19 vaccines, researchers have demonstrated a successful way to deliver a potential HIV vaccine, researchers at Duke Human Vaccine Institute report.

14-Mar-2022 4:00 PM EDT
Hitting a Wall
Harvard Medical School

Researchers have identified a new mechanism that regulates the permeability of the blood-brain barrier in mice

Newswise: Gravitational Wave Mirror Experiments Can Evolve Into Quantum Entities
14-Mar-2022 1:55 PM EDT
Gravitational Wave Mirror Experiments Can Evolve Into Quantum Entities
American Institute of Physics (AIP)

In AVS Quantum Science, scientists in Germany review research on gravitational wave detectors as a historical example of quantum technologies and examine the fundamental research on the connection between quantum physics and gravity. The team examined recent gravitational wave experiments, showing it is possible to shield large objects from strong influences from the thermal and seismic environment to allow them to evolve as one quantum object. This decoupling from the environment enables measurement sensitivities that would otherwise be impossible.

Newswise: Optimizer Tool Designs, Evaluates, Maximizes Solar-Powered Cooling Systems
10-Mar-2022 9:45 AM EST
Optimizer Tool Designs, Evaluates, Maximizes Solar-Powered Cooling Systems
American Institute of Physics (AIP)

In the Journal of Renewable and Sustainable Energy, researchers have developed an optimizer tool to design, evaluate, and maximize the performance of different types of solar-powered adsorption under various operating scenarios. The tool was created using Visual Basic programming language that is easy to learn and enables rapid application development and predicted the proper material mass concentration ratios. The method calculated the cooling load, predicted maximal performance, and conducted the overall performance analysis of the cooling system.

Newswise: Treating Cancer with Light-Sensitive Nanoscale Biomaterials
9-Mar-2022 10:40 AM EST
Treating Cancer with Light-Sensitive Nanoscale Biomaterials
American Institute of Physics (AIP)

Treating cancer and other diseases with laser light is not currently considered routine, but new approaches using nanoparticles show some promise in improving existing techniques. In Applied Physics Reviews, researchers review the status of the field and by combining photothermal therapy or photodynamic therapy with nanomaterials, they have been able to apply these types of phototherapies while also delivering drugs to sites in the body that are otherwise inaccessible. It is also possible to combine PTT and PDT into a single treatment, creating an even more powerful treatment method.

   
Released: 15-Mar-2022 10:50 AM EDT
Novel CRISPR Imaging Technology Reveals Genes Controlling Tumor Immunity
Mount Sinai Health System

Mount Sinai scientists have developed a new technology allowing them to link specific genes to complex tumor characteristics at a scale and resolution not previously possible. The results could lead to new approaches for targeting anti-cancer drugs.

Newswise: New sabre-tooth predator precedes cats by millions of years
Released: 15-Mar-2022 10:45 AM EDT
New sabre-tooth predator precedes cats by millions of years
PeerJ

The fossil, housed in The Nat’s paleontology collection, offers a window into what the Earth was like during the Eocene Period, more than 40 million years ago.

Released: 15-Mar-2022 10:40 AM EDT
Groundbreaking earthquake discovery: Risk models overlook an important element
University of Copenhagen

Earthquakes themselves affect the movement of Earth's tectonic plates, which in turn could impact on future earthquakes, according to new research from the University of Copenhagen.

Released: 15-Mar-2022 10:35 AM EDT
Delayed recovery of consciousness is common for COVID patients on respirators
Weill Cornell Medicine

Most patients with severe COVID who are put on ventilators regain consciousness after removal of respiratory support, but recovery may take weeks after the period of mechanical ventilation has ended, according to a new study by investigators at Weill Cornell Medicine, Columbia University Vagelos College of Physicians and Surgeons, Harvard Medical School, NewYork-Presbyterian and Massachusetts General Hospital.

Released: 15-Mar-2022 10:25 AM EDT
How you think about money affects what you do with it
University of Georgia

You know you should set aside savings with every paycheck, live within your means and invest your money wisely. But do you do it? New research from the University of Georgia suggests that answering three questions could give people insight into their spending and potentially help them modify their behavior in the future.

Newswise: New Genome Editing Tools Can Edit Within Microbial Communities
Released: 15-Mar-2022 10:20 AM EDT
New Genome Editing Tools Can Edit Within Microbial Communities
Department of Energy, Office of Science

Natural microbial communities contain multiple species of bacteria, making it difficult to isolate and culture individual bacterial species. Two new tools allow researchers to genetically manipulate distinct bacterial species within their communities. Combined, these tools give researchers the ability to track genetic modifications as the community grows and to examine gene function in microorganisms that cannot be grown in the lab.

Released: 15-Mar-2022 10:05 AM EDT
Vaccine protects against ‘tough cookie’ parasite found in the Americas
Ohio State University

The parasites that cause a disfiguring skin disease affecting about 12 million people globally may have met their match in vaccines developed using CRISPR gene-editing technology, new research suggests.

Newswise: Higher Dose Antibiotic Shown Safe in TB Patients Likely More Effective in Treating Deadliest Form of TB
Released: 15-Mar-2022 10:00 AM EDT
Higher Dose Antibiotic Shown Safe in TB Patients Likely More Effective in Treating Deadliest Form of TB
Johns Hopkins Medicine

A Johns Hopkins Children’s Center-led study in animals suggests that high doses of a widely used antibiotic called rifampin may safely treat and reduce the duration of treatment for the deadliest form of tuberculosis that affects the brain.

Newswise: Record-breaking, ultrafast devices step to protecting the grid from EMPs
Released: 15-Mar-2022 10:00 AM EDT
Record-breaking, ultrafast devices step to protecting the grid from EMPs
Sandia National Laboratories

Scientists from Sandia National Laboratories have announced a tiny, electronic device that can shunt excess electricity within a few billionths of a second while operating at a record-breaking 6,400 volts — a significant step towards protecting the nation’s electric grid from an electromagnetic pulse.

Released: 15-Mar-2022 9:55 AM EDT
Study of Non-Cancer Pain Patient Data Finds State Opioid Prescription Laws Don’t Influence Prescribing Practices
Johns Hopkins Bloomberg School of Public Health

Pain experts and patient advocates had expressed concern that these laws may restrict access to opioid treatment for people with chronic pain without substituting effective non-opioid alternatives.

Released: 15-Mar-2022 9:35 AM EDT
International Multi-Center Study Confirms Stroke Risk in Younger Healthier COVID-19 Patients
Thomas Jefferson University

The largest study on severe stroke and COVID-19 published to date found even moderate COVID-19 infection increased risk of death in younger, healthier stroke patients



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