UNC-Chapel Hill scientists and colleagues provide indirect evidence for the existence of a distinct latent reservoir of CD4+ T cells in the central nervous system, by analyzing rebound virus in the cerebral spinal fluid during the period when people had just stopped taking ART.
A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.
UC San Diego scientists developed an artificial intelligence tool that could accelerate the development of new high affinity antibody drugs.
A new biomaterial that can be injected intravenously, reduces inflammation in tissue and promotes cell and tissue repair. The biomaterial was tested and proven effective in treating tissue damage caused by heart attacks in both rodent and large animal models. Researchers also provided proof of concept in a rodent model that the biomaterial could be beneficial to patients with traumatic brain injury and pulmonary arterial hypertension.
New Cornell research is providing a fresh view into the ways a common chemotherapy agent, etoposide, stalls and poisons the essential enzymes that allow cancer cells to flourish.
Scientists have developed a new lithium-ion battery cathode that is free of cobalt, making it more attractive geopolitically.
The speed of environmental change is very challenging for wild organisms. When exposed to a new environment individual plants and animals can potentially adjust their biology to better cope with new pressures they are exposed to - this is known as phenotypic plasticity.
On Oct. 5, 2020, the rapidly rotating corpse of a long-dead star about 30,000 light years from Earth changed speeds. In a cosmic instant, its spinning slowed. And a few days later, it abruptly started emitting radio waves.
The Department of Energy Systems Biology Knowledgebase (KBase) recently released a suite of features and a protocol for performing sophisticated microbiome analysis that can accelerate research in microbial ecology. KBase helps researchers understand which organisms live in an environment and how they interact. The tool’s new features reduce the time required to process sequencing data and characterize genomes and help scientists collaboratively analyze genomics data and build research communities.
The Latest Permian Mass Extinction (LPME) was the largest extinction in Earth’s history to date, killing between 80-90% of life on the planet, though finding definitive evidence for what caused the dramatic changes in climate has eluded experts.
A new species of microalgae was found in water from a home aquarium. While analyzing DNA samples taken from the algae, researchers from the University of Tokyo discovered Medakamo hakoo, whose DNA sequence didn’t match any on record.
Johns Hopkins Medicine investigators say their research indicates a new combination of drugs is needed to find an effective treatment for TB meningitis due to multidrug-resistant (MDR) strains
A University of Queensland-led study has shown that expanding global seaweed farming could go a long way to addressing the planet’s food security, biodiversity loss and climate change challenges.
China is a night-time ‘hot-spot’ for the production of nitrate radicals (PNO3) that could have a major impact on health-threatening ozone and fine particulates (PM2.5) in the atmosphere, a new study reveals.
As lithium-ion batteries have become a ubiquitous part of our lives through their use in consumer electronics, automobiles and electricity storage facilities, researchers have been working to improve their power, efficiency and longevity. As detailed in a paper published today in Nature Materials, scientists at the University of California, Irvine and Brookhaven National Laboratory conducted a detailed examination of high-nickel-content layered cathodes, considered to be components of promise in next-generation batteries.
Investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have found that a subset of mutations within the overall TMB, termed “persistent mutations,” are less likely to be edited out as cancer evolves, rendering tumors continuously visible to the immune system and predisposing them to respond to immunotherapy.
Researchers use cutting-edge X-ray techniques to observe how an operating solid-state battery degrades.
Human brain atlases can be used by medical professionals to track normative trends over time and to pinpoint crucial aspects of early brain development. By using these atlases, they are able to see what typical structural and functional development looks like, making it easier for them to spot the symptoms of abnormal development, such as attention-deficit / hyperactivity disorder (ADHD), dyslexia, and cerebral palsy.
Long-term treatment of healthy middle-aged mice with a cancer drug increases lifespan by 10% on average, equivalent to 3 years.
In recent years, there have been increasing reports of toxic blue-green algae blooms in summer, even in German lakes, caused by climate warming and increased nutrient inputs.
After years of research, an NIH-funded team has developed a wearable cardiac ultrasound imager that can non-invasively capture real-time images of the human heart. The prototype patch, which is about the size of a postage stamp, can be worn during exercise, providing valuable cardiac information when the heart is under stress.
Engineers and physicians have developed a wearable ultrasound device that can assess both the structure and function of the human heart. The portable device, which is roughly the size of a postage stamp, can be worn for up to 24 hours and works even during strenuous exercise.
Below is a brief roundup of news and story ideas from the experts at UCLA Health.
Tungsten heavy alloys show promise for nuclear fusion energy development, according to new research conducted at PNNL.
UCSF researchers systematically tested CSF1R inhibition using multiple drug analogs at several time points in transgenic mice developing spontaneous tauopathy. The researchers demonstrated a reduction of tau pathology in multiple dosing schemes without complete microglial ablation.
This study provides a mechanism for rapidly identifying the protein kinase that is driving the abnormal behavior of individual cancers.
Just as a choreographer’s notation tells a dancer to strike a particular pose, an enzyme newly discovered by Rice University scientists is able to tell specific molecules precisely how to arrange themselves, down to the angle of single hydrogen bonds.
Recent high temperatures on the ice sheet in central and northern Greenland lies are unique, when compared to 1000 years of reconstructed climate conditions on the ice sheet.
Recent experiments have shown that the loss of species from a plant community can reduce ecosystem functions and services such as productivity, carbon storage and soil health.
A team led by researchers at the University of Washington studied how artificial intelligence could help people on the platform TalkLife, where people give each other mental health support. The researchers developed an AI system that suggested changes to participants’ responses to make them more empathetic. The best responses resulted from a collaboration between AI and people.
The discovery of diverse ices in the darkest regions of a cold molecular cloud measured to date has been announced by an international team of astronomers using NASA’s James Webb Space Telescope. This result allows astronomers to examine the simple icy molecules that will be incorporated into future exoplanets, while opening a new window on the origin of more complex molecules that are the first step in the creation of the building blocks of life.
Scientists working in connectomics are creating comprehensive maps of how neurons connect to one another
Matter outflows in the form of jets are observed in astronomical systems at fast, medium and slow speeds. The fastest jets are highly relativistic, namely travel very close to the speed of light. The origin, as well as many properties of the jets, is uncertain.
A new study by researchers from Durham University, UK, Queen’s University Belfast, UK, University of Extremadura, Spain and Swansea University, UK have revealed that vertebrate species involved in the live wildlife trade have distinctive life history traits, biological characteristics that determine the frequency and timing of reproduction.
Steel is one of the most important materials in the world, integral to the cars we drive, the buildings we inhabit, and the infrastructure that allows us to travel from place to place.
Physicists from the STAR Collaboration have reported the first observation of a global spin alignment signal in heavy-ion collisions. Published in Nature on Jan. 18, the study provides a potential new avenue for understanding the strong interaction at work at the sub-nucleon level.
The next frontier of continuous health monitoring could be skin deep.
Investigating the interplay between the structure of water molecules that have been incorporated into layered materials such as clays and the configuration of ions in such materials has long proved a great experimental challenge.
An increase in anti-Chinese sentiment has led to consumer discrimination against Asian American-owned small businesses, according to new Ross School of Business research.
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a new drug target for Ewing sarcoma, a rare kind of cancer usually diagnosed in children and young adults. Their experiments show that the cells causing this cancer can essentially be reprogrammed with the flick of a genetic switch.
A transdisciplinary Northwestern University research team has developed a revolutionary transistor that is expected be ideal for lightweight, flexible, high-performance bioelectronics.
Methanogens are microorganisms that produce methane when little or no oxygen is present in their surroundings.
New research reveals the genes that likely allowed whales to grow to giant sizes compared to their ancestors, reports a study published in Scientific Reports.
Researchers have designed the first ‘living medicine’ to treat lung infections.
Two major health conditions appear to share a connection. Multiple sclerosis (MS), a disease which eats away at the body’s central nervous system, affects millions of people globally and depression, a mood disorder with debilitating symptoms, affects hundreds of millions of people globally.
Nearly 100 million years ago, the Earth experienced an extreme environmental disruption that choked oxygen from the oceans and led to elevated marine extinction levels that affected the entire globe.
Nearly half a million people missed out on starting medication to lower their blood pressure during the Covid-19 pandemic, according to research supported by the British Heart Foundation (BHF) Data Science Centre at Health Data Research UK published today in Nature Medicine [1].
Climate change and human activities strongly influence forests, but researchers have not fully understood the pervasiveness of these stressors and how they will shape future forest structure.
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