A large, multi-center study led by Johns Hopkins researchers has found a significant link between lifestyle factors and heart health, adding even more evidence in support of regular exercise, eating a Mediterranean-style diet, keeping a normal weight and, most importantly, not smoking.
A study at the University of California, San Diego School of Medicine identified a protein that is responsible for regulating blood vessel growth by mediating the efficient removal of cholesterol from the cells. Unregulated development of blood vessels can feed the growth of tumors.
• Compared with kidney disease patients who had zero or one heart healthy lifestyle component in the ideal range, those with two, three, and four ideal factors had progressively lower risks for kidney failure over four years. • No kidney disease patients with five to seven ideal factors developed kidney failure. • Patients’ risk of dying during the study followed a similar trend
New research from the UAB School of Public Health shows that patients with chronic kidney disease may improve their health by making lifestyle behavior changes.
UCLA researchers examining outcomes for advanced heart-failure patients over the past two decades have found that, coinciding with the increased availability and use of new therapies, overall mortality has decreased and sudden cardiac death, caused by the rapid onset of severe abnormal heart rhythms, has declined. However, the team found that even today, with these significant improvements, one-third of patients don’t survive more than three years after being diagnosed with advanced disease.
Patients with underlying heart failure are more likely to experience adverse outcomes from mild hypothyroidism, according to a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
A drug commonly used to treat depression and anxiety may improve a stress-related heart condition in people with stable coronary heart disease, according to researchers at Duke Medicine.
Both fine-particle air pollution and noise pollution may increase a person’s risk of developing cardiovascular disease, according to German researchers who have conducted a large population study, in which both factors were considered simultaneously.
A newer class of medications used to control blood sugar levels in type 2 diabetics may also improve cardiovascular health, researchers from The Ohio State University Wexner Medical Center reported.
The gene Dkk1 encodes a protein that plays a key role in increasing the population of connective-tissue cells during wound repair, but prolonged Dkk1 signaling in cells lining blood vessels can lead to fibrosis and a stiffening of artery walls.
Academic researchers have found that breathing motor vehicle emissions triggers a change in high-density lipoprotein (HDL) cholesterol, altering its cardiovascular protective qualities so that it actually contributes to clogged arteries. The finding, shown in mice, reveals how car emissions activate the early cell and tissue damage called oxidation that causes inflammation leading to hardening of the arteries and HDL cholesterol may play a key role.
Scientists at the Texas Biomedical Research Institute in San Antonio have identified four genes in baboons that influence levels of “bad” cholesterol. This discovery could lead to the development of new drugs to reduce the risk of heart disease.
The general training program used by most cardiac rehabs follows national guidelines but these programs often do not meet the various physical requirements of specific workplaces.
Strokes rates are high among African Americans, but concerns about medical cost, ambulance response time and unfamiliarity with the need for prompt hospital care impacted whether they called 9-1-1 immediately.
As part of a new personalized medicine initiative, the University of Maryland Medical Center is offering genetic testing to help doctors determine which medication a patient should take after a stenting procedure in order to prevent blood clots that could lead to serious – and potentially fatal – heart attacks and strokes.
Some materials dissolve too quickly, before cardiac arteries can fully heal, and some hang around forever. Zinc, however, may be just right.
Total anomalous pulmonary venous connection, one type of “blue baby” syndrome, is a potentially deadly congenital disorder that occurs when pulmonary veins don’t connect normally to the left atrium of the heart. TAPVC babies are born cyanotic from lack of oxygen. Semaphorin 3d guides the development of endothelial cells and is crucial for normal development of pulmonary veins. Mutations in Sema3d cause embryonic blood vessels to hook up in the wrong way.
Programming an implantable cardioverter-defibrillator (ICD) with a long-detection interval compared with a standard-detection interval resulted in a reduction in anti-tachycardia pacing episodes, ICD shocks delivered, and inappropriate shocks, according to a study in the May 8 issue of JAMA.
A study appearing in the Journal of Nutritional Biochemistry demonstrates that grapes are able to reduce heart failure associated with hypertension by increasing the activity of several genes responsible for antioxidant defense in the heart tissue.
When teenage girls are exposed to secondhand smoke at home, they tend to have lower levels of the “good” form of cholesterol that reduces heart disease risk, according to a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
Researchers claim to have calculated for the first time, the upper safe limit of vitamin D levels, above which the associated risk for cardiovascular events or death raises significantly, according to a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
Your genetic makeup can help determine how well your body will respond to weight loss efforts aimed at controlling high blood pressure, a new study confirms. The multi-institutional study, led by researchers at The Cardiovascular Institute, part of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, may help clarify how hypertension develops and progresses in certain individuals and also identify people for whom weight loss programs are most likely to help reduce blood pressure.
Researchers at Washington University School of Medicine in St. Louis have described a missing link in understanding how damage to the body’s cellular power plants leads to Parkinson’s disease and, perhaps surprisingly, to some forms of heart failure.
Using a one-of-a-kind computer-aided program, Mayo Clinic has developed and implemented a Mayo-wide electronic warning system to identify patients at risk of QT-related deaths from an abnormality in the heart’s electrical system. The system informs all physicians, regardless of their specialty or QT awareness, if their patient’s ECG activated the QT alarm. In addition, the researchers discovered that the death rate of patients whose 12-lead electrocardiogram (ECG) activated the QT alert was nearly four times greater than all other patients who had an ECG. The findings are published in the current issue of Mayo Clinic Proceedings.
Long-term exposure to air pollution may be linked to heart attacks and strokes by speeding up atherosclerosis, or "hardening of the arteries," according to a University of Michigan public health researcher and colleagues from across the U.S.
Taking a specific form of a vitamin E supplement can accelerate the health benefits that occur when people quit smoking, new research suggests.
Consuming grapes may help protect against organ damage associated with the progression of metabolic syndrome, according to research presented this week at the Experimental Biology conference in Boston.
Hair strands contain valuable information about senior citizens’ stress levels that can be used to determine an individual’s cardiovascular disease risk, according to a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
A new study by University of North Carolina School of Medicine researchers finds that patients who suffer a STEMI heart attack while hospitalized are 10 times more likely to die than patients who suffer a STEMI outside the hospital.
A common test that records the heart’s electrical activity could predict potentially serious cardiovascular illness, according to a UC San Francisco-led study.
New finding in European Heart Journal contradicts recent study in the same publication; suggests evidence is lacking that digoxin increases mortality as a treatment for atrial fibrillation.
Findings pinpoint 14 genetic targets in humans that may provide insight for the treatment of cardiovascular disease.
Researchers at the University of Michigan have identified a new potential therapeutic target for lowering cholesterol that could be an alternative or complementary therapy to statins.
Translating a Mayo Clinic stem-cell discovery, an international team has demonstrated that therapy with cardiopoietic (cardiogenically-instructed) or “smart” stem cells can improve heart health for people suffering from heart failure. This is the first application in patients of lineage-guided stem cells for targeted regeneration of a failing organ, paving the way to development of next generation regenerative medicine solutions. Results of the clinical trial appear online of the Journal of the American College of Cardiology.
Mayo Clinic physicians in Arizona have shown that tablet computers can be used to analyze electroencephalogram or EEG results outside of the clinic or hospital. Their study findings were recently presented at the American Academy of Neurology conference in San Diego.
A UCLA study shows that heart failure medications recommended by national guidelines are highly cost effective in saving lives and may also provide savings to the health care system.
Certified Primary Stroke Centers are three times more likely to administer clot-busting treatment for strokes than non-certified centers, reports a new study by researchers in the Perelman School of Medicine at the University of Pennsylvania.
In what promises to be an eye-opener for many doctors and patients who routinely depend on cholesterol testing, a study led by researchers at the Johns Hopkins University School of Medicine found that the standard formula used for decades to calculate low-density lipoprotein (LDL) cholesterol levels is often inaccurate. Of most concern, the researchers say, is their finding that the widely used formula underestimates LDL where accuracy matters most — in the range considered desirable for high-risk patients. Results of the study are published in an online article, ahead of print, in the Journal of the American College of Cardiology.
UCLA researchers have genetically engineered tomatoes to produce a peptide that mimics the actions of good cholesterol when consumed. In this early study, mice that were fed these tomatoes in freeze-dried, ground form had less inflammation and plaque build-up in their arteries.
A new study in the March 2013 Women’s Health Issues evaluates the Heart Truth educational campaign on provider knowledge of heart disease as it affects women. The team of researchers studied the delivery of The Heart Truth® Professional Education Campaign across three states to diverse audiences of healthcare providers. All of the healthcare providers showed improved knowledge on women and heart disease after participating in the lectures.
For the first time, a UCLA team has used a technique normally employed in treating brain aneurysms to treat severe, life-threatening irregular heart rhythms in two patients.
Millions of Americans take drugs to reduce their risk of heart attacks caused by blood clots. A new study suggests that a fear of brain bleeding if these patients receive stroke therapy may be unfounded, at least for most patients taking common clot-preventing therapies.
Data show need for OB/GYNs to play expanded role in educating, preventing heart disease for women in reproductive years.
Reduced costs, favorable outcomes with three-catheter ablation procedure in patients with Wolff-Parkinson-White Syndrome.
A single dose of an investigational anti-inflammatory drug called inclacumab considerably reduces damage to heart muscle during angioplasty (the opening of a blocked artery), according to a recent international clinical trial spearheaded by Dr. Jean-Claude Tardif, Director of the Research Centre at the Montreal Heart Institute, affiliated with the University of Montreal.
While two large clinical trials recently showed that adding niacin to statin therapy failed to improve clinical outcomes despite a significant increase in HDL-C levels, little is known about exactly why the increased HDL-C levels did not reduce the risk of cardiovascular events, including heart attack and stroke. Now, a small study from researchers the Perelman School of Medicine at the University of Pennsylvania, has shown that while niacin increased measured levels of HDL-C, it did not improve the functionality of HDL. This may provide an explanation for the failure of niacin to further reduce cardiovascular risk. The study results were reported today at the 62nd Annual Scientific Session of the American College of Cardiology in San Francisco.
New research from a multidisciplinary team at the Perelman School of Medicine at the University of Pennsylvania has shown that the combination of CPAP and weight loss for patients with OSA can help lower blood pressure better than either therapy alone. The study results were reported today at the 62nd Annual Scientific Session of the American College of Cardiology in San Francisco.
Award will support investigations of leading cause of sudden death in young people
Researchers use MRI to determine that thinned heart muscle can be saved and reversed with proper treatment.
RSS
Medicine keyboard_arrow_right
Sciencekeyboard_arrow_right
Life keyboard_arrow_right
Business keyboard_arrow_right
Journal News keyboard_arrow_right
By Location keyboard_arrow_right
Meetings, Grants, and Events keyboard_arrow_right